Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 JAK-STAT signaling pathway 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 JAK-STAT signaling pathway 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 JAK-STAT signaling pathway 💬
1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
4 JAK-STAT signaling pathway 💬
1件: CSF2RA 💬 Mavrilimumab 💬 Mavrilimumab 2件: 41, 46 💬
5 JAK-STAT signaling pathway 💬
1件: CSF2RA 💬 Molgramostim 💬 Molgramostim 2件: 229, 299 💬
6 JAK-STAT signaling pathway 💬
1件: CSF2RA 💬 Regramostim 💬 Regramostim 1件: 229 💬
7 JAK-STAT signaling pathway 💬
1件: CSF2RA 💬 Sargramostim 💬 Sargramostim 7件:  6 , 28, 60, 62, 96, 229, 285 💬
8 JAK-STAT signaling pathway 💬
1件: CSF3R 💬 Filgrastim 💬 Filgrastim 29件:  2 ,  6 , 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
9 JAK-STAT signaling pathway 💬
1件: CSF3R 💬 Lenograstim 💬 Lenograstim 8件:  2 , 13, 16, 18, 19, 57, 65, 97 💬
10 JAK-STAT signaling pathway 💬
1件: CSF3R 💬 Pegfilgrastim 💬 Pegfilgrastim 1件: 60 💬
11 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
12 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
13 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
14 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
15 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
16 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
17 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
18 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
19 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
20 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
21 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
22 JAK-STAT signaling pathway 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
23 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Epoetin beta 💬 Epoetin beta 2件: 13, 18 💬
24 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Epoetin alfa 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
25 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Epoetin epsilon 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
26 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Epoetin theta 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
27 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Epoetin zeta 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
28 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Peginesatide 💬 Peginesatide 1件: 283 💬
29 JAK-STAT signaling pathway 💬
1件: EPOR 💬 Peginesatide acetate 💬 Peginesatide 1件: 283 💬
30 JAK-STAT signaling pathway 💬
1件: GHR 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
31 JAK-STAT signaling pathway 💬
1件: GHR 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
32 JAK-STAT signaling pathway 💬
1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 77, 265 💬
33 JAK-STAT signaling pathway 💬
1件: GHR 💬 Somapacitan 💬 Somapacitan 1件: 195 💬
34 JAK-STAT signaling pathway 💬
1件: GHR 💬 Somatropin 💬 Somatotropin 28件:  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
35 JAK-STAT signaling pathway 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
36 JAK-STAT signaling pathway 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
37 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
38 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
39 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
40 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
41 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
42 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
43 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
44 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
45 JAK-STAT signaling pathway 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
46 JAK-STAT signaling pathway 💬
1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
47 JAK-STAT signaling pathway 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
48 JAK-STAT signaling pathway 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
49 JAK-STAT signaling pathway 💬
2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
50 JAK-STAT signaling pathway 💬
2件: IL10, IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
51 JAK-STAT signaling pathway 💬
1件: IL11RA 💬 Oprelvekin 💬 Oprelvekin 3件: 96, 97, 288 💬
52 JAK-STAT signaling pathway 💬
3件: IL12A, IL12B, IL23A 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
53 JAK-STAT signaling pathway 💬
1件: IL13 💬 Anrukinzumab 💬 Anrukinzumab 1件: 97 💬
54 JAK-STAT signaling pathway 💬
1件: IL13 💬 Cendakimab 💬 Cendakimab 1件: 98 💬
55 JAK-STAT signaling pathway 💬
1件: IL13 💬 Lebrikizumab 💬 Lebrikizumab 1件: 85 💬
56 JAK-STAT signaling pathway 💬
1件: IL13 💬 Tralokinumab 💬 Tralokinumab 2件: 85, 97 💬
57 JAK-STAT signaling pathway 💬
1件: IL20 💬 Fletikumab 💬 Fletikumab 1件: 46 💬
58 JAK-STAT signaling pathway 💬
1件: IL22 💬 Efmarodocokin alfa 💬 Efmarodocokin alfa 2件: 96, 97 💬
59 JAK-STAT signaling pathway 💬
1件: IL23A 💬 Brazikumab 💬 Brazikumab 2件: 96, 97 💬
60 JAK-STAT signaling pathway 💬
1件: IL23A 💬 Guselkumab 💬 Guselkumab 7件: 37, 41, 51, 96, 97, 161, 269 💬
61 JAK-STAT signaling pathway 💬
1件: IL23A 💬 Mirikizumab 💬 Mirikizumab 3件: 37, 96, 97 💬
62 JAK-STAT signaling pathway 💬
1件: IL23A 💬 Risankizumab 💬 Risankizumab 4件: 37, 96, 97, 271 💬
63 JAK-STAT signaling pathway 💬
1件: IL23A 💬 Tildrakizumab 💬 Tildrakizumab 2件: 162, 271 💬
64 JAK-STAT signaling pathway 💬
1件: IL2RA 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
65 JAK-STAT signaling pathway 💬
1件: IL2RA 💬 Basiliximab 💬 Basiliximab 5件:  2 , 50, 97, 222, 228 💬
66 JAK-STAT signaling pathway 💬
1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
67 JAK-STAT signaling pathway 💬
3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
68 JAK-STAT signaling pathway 💬
1件: IL31RA 💬 Nemolizumab 💬 Nemolizumab 1件: 51 💬
69 JAK-STAT signaling pathway 💬
1件: IL4R 💬 Dupilumab 💬 Dupilumab 5件: 51, 97, 98, 160, 162 💬
70 JAK-STAT signaling pathway 💬
1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
71 JAK-STAT signaling pathway 💬
1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
72 JAK-STAT signaling pathway 💬
1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
73 JAK-STAT signaling pathway 💬
1件: IL5RA 💬 Benralizumab 💬 Benralizumab 5件: 44, 45, 98, 162, 299 💬
74 JAK-STAT signaling pathway 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
75 JAK-STAT signaling pathway 💬
1件: IL6 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
76 JAK-STAT signaling pathway 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
77 JAK-STAT signaling pathway 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
78 JAK-STAT signaling pathway 💬
1件: IL6R 💬 Sarilumab 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬
79 JAK-STAT signaling pathway 💬
1件: IL6R 💬 Satralizumab 💬 Satralizumab 4件: 11, 13, 86, 113 💬
80 JAK-STAT signaling pathway 💬
1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 24件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
81 JAK-STAT signaling pathway 💬
1件: IL7R 💬 Lusvertikimab 💬 Lusvertikimab 1件: 97 💬
82 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
83 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
84 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
85 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
86 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
87 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
88 JAK-STAT signaling pathway 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
89 JAK-STAT signaling pathway 💬
2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
90 JAK-STAT signaling pathway 💬
2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
91 JAK-STAT signaling pathway 💬
2件: JAK1, JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
92 JAK-STAT signaling pathway 💬
3件: JAK1, JAK2, JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
93 JAK-STAT signaling pathway 💬
3件: JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
94 JAK-STAT signaling pathway 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
95 JAK-STAT signaling pathway 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
96 JAK-STAT signaling pathway 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
97 JAK-STAT signaling pathway 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
98 JAK-STAT signaling pathway 💬
1件: JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
99 JAK-STAT signaling pathway 💬
1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
100 JAK-STAT signaling pathway 💬
1件: LEPR 💬 Metreleptin 💬 Metreleptin 1件: 265 💬
101 JAK-STAT signaling pathway 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
102 JAK-STAT signaling pathway 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
103 JAK-STAT signaling pathway 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
104 JAK-STAT signaling pathway 💬
1件: OSMR 💬 Vixarelimab 💬 Vixarelimab 3件: 51, 85, 97 💬
105 JAK-STAT signaling pathway 💬
1件: PDGFRA 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
106 JAK-STAT signaling pathway 💬
1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
107 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
108 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
109 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
110 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
111 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
112 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Seralutinib 💬 Seralutinib 1件: 86 💬
113 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
114 JAK-STAT signaling pathway 💬
2件: PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
115 JAK-STAT signaling pathway 💬
1件: PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
116 JAK-STAT signaling pathway 💬
1件: PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
117 JAK-STAT signaling pathway 💬
2件: PDGFRB, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
118 JAK-STAT signaling pathway 💬
2件: PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
119 JAK-STAT signaling pathway 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
120 JAK-STAT signaling pathway 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
121 JAK-STAT signaling pathway 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
122 JAK-STAT signaling pathway 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
123 JAK-STAT signaling pathway 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
124 JAK-STAT signaling pathway 💬
1件: PRL 💬 Bromocriptine mesylate 💬 Bromocriptine 2件:  6 , 74 💬
125 JAK-STAT signaling pathway 💬
1件: PRL 💬 Bromocriptine 💬 Bromocriptine 2件:  6 , 74 💬
126 JAK-STAT signaling pathway 💬
1件: PRL 💬 Cabergoline 💬 Cabergoline 4件:  6 , 74, 75, 77 💬
127 JAK-STAT signaling pathway 💬
1件: PRL 💬 Terguride 💬 Terguride 2件: 51, 86 💬
128 JAK-STAT signaling pathway 💬
1件: TPOR 💬 Avatrombopag 💬 Avatrombopag 2件: 60, 63 💬
129 JAK-STAT signaling pathway 💬
1件: TPOR 💬 Avatrombopag maleate 💬 Avatrombopag 2件: 60, 63 💬
130 JAK-STAT signaling pathway 💬
1件: TPOR 💬 Eltrombopag olamine 💬 Eltrombopag 5件: 60, 63, 65, 284, 285 💬
131 JAK-STAT signaling pathway 💬
1件: TPOR 💬 Eltrombopag choline 💬 Eltrombopag 5件: 60, 63, 65, 284, 285 💬
132 JAK-STAT signaling pathway 💬
1件: TPOR 💬 Lusutrombopag 💬 Lusutrombopag 2件: 60, 63 💬
133 JAK-STAT signaling pathway 💬
1件: TPOR 💬 Romiplostim 💬 Romiplostim 4件: 60, 63, 64, 65 💬
134 JAK-STAT signaling pathway 💬
1件: TSLP 💬 Tezepelumab 💬 Tezepelumab 3件: 44, 45, 98 💬
135 JAK-STAT signaling pathway 💬
1件: TSLPR 💬 Solrikitug 💬 Solrikitug 1件: 98 💬
136 JAK-STAT signaling pathway 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
137 JAK-STAT signaling pathway 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬