109. 非典型溶血性尿毒症症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 123 / 薬物数 : 29 - (DrugBank : 6) / 標的遺伝子数 : 2 - 標的パスウェイ数 : 11
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
ALN-CC5
Alnylam Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2017-001082-24-SE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LV Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LT Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-EE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
2019 Phase 2 EUCTR2018-004382-13-IT Italy
ALXN1210
ALEXION PHARMACEUTICALS INCORPORATED
2017 Phase 3 EUCTR2016-002027-29-IT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Alexion Pharmaceuticals Inc.
2017 Phase 3 EUCTR2016-002499-29-DE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-DE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Alexion Pharmaceuticals Incorporated
2019 Phase 3 EUCTR2016-002499-29-FR Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-SE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-IT Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-GB Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-ES Spain;United States
2017 Phase 3 EUCTR2016-002499-29-BE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-AT Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-SE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-ES Austria;Belgium;Czech Republic;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-BE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2016 Phase 3 EUCTR2016-002027-29-GB Australia;Austria;Belgium;Czech Republic;France;Germany;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2016 Phase 3 EUCTR2016-002027-29-AT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
- Phase 3 EUCTR2016-002027-29-CZ Australia;Austria;Belgium;Czech Republic;France;Germany;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
ANTI-C5 antibody
ALEXION PHARMACEUTICALS, INC.
2013 Phase 2 EUCTR2010-020326-18-FR Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020326-18-NL Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-BE Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-NL Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-GB Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-ES Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2011 - EUCTR2010-020310-28-DE Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020310-28-BE Australia;Austria;Belgium;Canada;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2010 - EUCTR2010-020326-18-GB Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020326-18-DE Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020310-28-AT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-SE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-NL Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006955-28-GB Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-DE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-AT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006954-17-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-SE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-NL Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-GB Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-DE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-AT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
- Phase 2 EUCTR2010-020310-28-FR Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
C5 INH MAB, SKY59, RO/CH7092230
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002475-35-IT Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002475-35-PL Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-HU Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-FR Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-DE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-BE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
CCX168
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
2015 Phase 2 EUCTR2014-004261-24-IT Italy
Mario Negri Institute for Pharmacological Research
2015 Phase 2 NCT02464891 Italy
Cemdisiran
Alnylam Pharmaceuticals
2017 Phase 2 NCT03303313 Bosnia and Herzegovina;Canada;Estonia;Georgia;Latvia;Lithuania;Macedonia, The Former Yugoslav Republic of;Moldova, Republic of;Serbia;Sweden
Alnylam Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2017-001082-24-SE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LV Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LT Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-EE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
2019 Phase 2 EUCTR2018-004382-13-IT Italy
Mario Negri Institute for Pharmacological Research
2021 Phase 2 NCT03999840 Italy
Coversin
Akari Therapeutics Plc
2019 Phase 3 EUCTR2016-004129-18-LT Argentina;France;Germany;India;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
2018 Phase 3 EUCTR2016-004129-18-NL Argentina;Lithuania;Netherlands;Poland;United Kingdom
2017 Phase 3 EUCTR2016-004129-18-PL Argentina;France;Germany;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
Crovalimab
Camelia Sima
2022 Phase 3 JPRN-jRCT2031210061 BELGIUM;BRAZIL;CANADA;CHINA;FRANCE;GERMANY;HUNGARY;ISRAEL;ITALY;Japan;MEXICO;PERU;POLAND;SOUTH AFRICA;SPAIN;TURKEY;UNITED STATES
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002475-35-IT Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002475-35-PL Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-HU Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-FR Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-DE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-BE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Hoffmann-La Roche
2021 Phase 3 NCT04958265 Belgium;Brazil;Canada;China;France;Hungary;India;Israel;Italy;Japan;Mexico;Poland;South Africa;Spain;United States
2021 Phase 3 NCT04861259 Belgium;Brazil;Canada;China;France;Germany;Hungary;India;Israel;Italy;Japan;Mexico;New Zealand;Peru;Poland;South Africa;Spain;Turkey;United States
Mona D. Shah
2022 Phase 3 JPRN-jRCT2041210086 Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Eculizumab
ALEXION PHARMACEUTICALS
2011 - EUCTR2010-020310-28-IT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-IT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-IT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
ALEXION PHARMACEUTICALS INCORPORATED
- Phase 4 EUCTR2015-003135-35-IT Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
ALEXION PHARMACEUTICALS, INC.
2013 Phase 2 EUCTR2010-020326-18-FR Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020326-18-NL Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-ES Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-BE Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-NL Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-GB Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-ES Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2011 - EUCTR2010-020310-28-DE Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020310-28-BE Australia;Austria;Belgium;Canada;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2010 - EUCTR2010-020326-18-GB Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020326-18-DE Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020310-28-AT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-SE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-NL Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006955-28-GB Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-ES Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-DE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-AT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006954-17-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-SE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-NL Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-GB Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-DE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-AT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
- Phase 2 EUCTR2010-020310-28-FR Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP)
2023 Phase 3 EUCTR2022-002329-84-FR France
Alexion Pharmaceuticals
2015 - NCT02614898 Australia;Germany;United Kingdom;United States
2012 Phase 2 NCT01757431 Japan
2010 Phase 2 NCT01194973 Belgium;France;Germany;Italy;Spain;United Kingdom;United States
2010 Phase 2 NCT01193348 Australia;Belgium;Canada;France;Germany;Italy;Netherlands;United Kingdom;United States
2009 Phase 2 NCT00844844 Austria;Canada;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
2009 Phase 2 NCT00844545 Austria;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
2009 Phase 2 NCT00844428 Austria;Canada;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
2009 Phase 2 NCT00838513 Austria;Canada;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
Alexion Pharmaceuticals, Inc.
2023 Phase 3 NCT05876351 China
2016 Phase 4 EUCTR2015-003135-35-DE Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
Children's Hospital Medical Center, Cincinnati
2018 Phase 2 NCT03518203 United States
HOSPITAL UNIVERSITARI DE BELLVITGE- IDIBELL
2019 Phase 4 EUCTR2019-001619-21-ES Spain
Nantes University Hospital
2015 Phase 4 NCT02574403 France
Newcastle Upon Tyne Hospitals NHS Foundation Trust
2018 Phase 2 EUCTR2017-003916-37-GB United Kingdom
FC- and CDR-modified humanised monoclonal antibody against C5
ALEXION PHARMACEUTICALS INCORPORATED
2017 Phase 3 EUCTR2016-002027-29-IT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Alexion Pharmaceuticals Inc.
2017 Phase 3 EUCTR2016-002499-29-DE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals Incorporated
2019 Phase 3 EUCTR2016-002499-29-FR Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-SE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-IT Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-GB Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-ES Spain;United States
2017 Phase 3 EUCTR2016-002499-29-BE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-AT Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-SE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-BE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2016 Phase 3 EUCTR2016-002027-29-AT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
- Phase 3 EUCTR2016-002027-29-CZ Australia;Austria;Belgium;Czech Republic;France;Germany;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Iptacopan
Iwasaki Ryohei
2024 Phase 3 JPRN-jRCT2031230686 China;France;Germany;Italy;Japan;Spain;Turkey;United Kingdom;United Status
Novartis Pharma AG
2022 Phase 3 EUCTR2020-005186-13-SK Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-CZ Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-AT Austria;Brazil;China;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovenia;Taiwan;United Kingdom;United States
Novartis Pharmaceuticals
2024 Phase 3 NCT05935215 China;Japan;Spain;Turkey;United Kingdom
2022 Phase 3 NCT04889430 Austria;Brazil;China;Czechia;Greece;India;Japan;Korea, Republic of;Slovakia;Slovenia;Taiwan;United Kingdom;United States
Iptacopan hydrochloride
Novartis Pharma AG
2021 Phase 3 EUCTR2020-005186-13-SI Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
Iptcaopan 200 MG
Novartis Pharmaceuticals
2024 Phase 3 NCT05795140 Brazil;China;Czechia;India
LNP023
Novartis Pharma AG
2022 Phase 3 EUCTR2020-005186-13-SK Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-SI Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-CZ Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-AT Austria;Brazil;China;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovenia;Taiwan;United Kingdom;United States
NM8074
NovelMed Therapeutics
2025 Phase 2 NCT05684159 -
OMS00620646, OMS620646, MASP-2 antibody
Omeros Corporation
2018 Phase 3 EUCTR2017-002057-11-PL Lithuania;Poland;Taiwan;United States
2017 Phase 3 EUCTR2017-002057-11-LT Lithuania;Poland;Taiwan;United States
OMS721
Omeros Corporation
2017 Phase 3 NCT03205995 United States
OMS721 100 MG/ML injection solution, OMS00620646, OMS620646, MASP-2 antibody
OMEROS CORPORATION
- Phase 2 EUCTR2014-001032-11-IT Belarus;Belgium;Bulgaria;Czechia;Germany;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
Omeros Corporation
2014 Phase 2 EUCTR2014-001032-11-PL Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
2014 Phase 2 EUCTR2014-001032-11-LT Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
2014 Phase 2 EUCTR2014-001032-11-BE Belarus;Belgium;Bulgaria;Germany;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
OMS721 185 MG/ML injection solution, OMS00620646, OMS620646, MASP-2 antibody
Omeros Corporation
2014 Phase 2 EUCTR2014-001032-11-PL Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
2014 Phase 2 EUCTR2014-001032-11-LT Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
OMS721 drug product 185 MG/ML
Omeros Corporation
2018 Phase 3 EUCTR2017-002057-11-PL Lithuania;Poland;Taiwan;United States
2017 Phase 3 EUCTR2017-002057-11-LT Lithuania;Poland;Taiwan;United States
Ravulizumab
Alexion
2017 Phase 3 NCT02949128 Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals Inc.
2017 Phase 3 EUCTR2016-002499-29-DE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals Incorporated
2017 Phase 3 EUCTR2016-002499-29-SE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-GB Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-BE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-AT Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals, Inc.
2017 Phase 3 NCT03131219 Belgium;Germany;Italy;Japan;Korea, Republic of;Spain;United Kingdom;United States
RO7112689/F03-01
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
RO7112689/F03-10
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002475-35-IT Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002475-35-PL Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-HU Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-FR Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-DE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-BE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
RVA576
Akari Therapeutics Plc
2019 Phase 3 EUCTR2016-004129-18-LT Argentina;France;Germany;India;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
2018 Phase 3 EUCTR2016-004129-18-NL Argentina;Lithuania;Netherlands;Poland;United Kingdom
2017 Phase 3 EUCTR2016-004129-18-PL Argentina;France;Germany;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
2017 Phase 3 EUCTR2016-004129-18-GB Argentina;France;Germany;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
Solaris
Newcastle Upon Tyne Hospitals NHS Foundation Trust
2018 Phase 2 EUCTR2017-003916-37-GB United Kingdom
Soliris
ALEXION PHARMACEUTICALS
2011 - EUCTR2010-020326-18-IT Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-IT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-IT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
ALEXION PHARMACEUTICALS INCORPORATED
- Phase 4 EUCTR2015-003135-35-IT Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
ALEXION PHARMACEUTICALS, INC.
2013 Phase 2 EUCTR2010-020326-18-FR Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020326-18-NL Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-BE Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-NL Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-GB Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-ES Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2011 - EUCTR2010-020310-28-DE Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020310-28-BE Australia;Austria;Belgium;Canada;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2010 - EUCTR2010-020326-18-GB Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020326-18-DE Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020310-28-AT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-SE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-NL Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006955-28-GB Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-DE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-AT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006954-17-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-SE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-NL Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-GB Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-DE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-AT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
- Phase 2 EUCTR2010-020310-28-FR Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
Alexion Pharmaceuticals, Inc.
2016 Phase 4 EUCTR2015-003135-35-DE Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
HOSPITAL UNIVERSITARI DE BELLVITGE- IDIBELL
2019 Phase 4 EUCTR2019-001619-21-ES Spain
Soliris 300 MG concentrado para solucióN para perfusióN
ALEXION PHARMACEUTICALS, INC.
2011 Phase 2 EUCTR2010-020326-18-ES Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-ES Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
Soliris 300 MG solution à diluer pour perfusion
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP)
2023 Phase 3 EUCTR2022-002329-84-FR France
Ultomiris
Alexion Pharmaceuticals, Inc.
2024 - NCT06312644 United States
Alnylam Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2017-001082-24-SE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LV Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LT Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-EE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
2019 Phase 2 EUCTR2018-004382-13-IT Italy
ALXN1210
ALEXION PHARMACEUTICALS INCORPORATED
2017 Phase 3 EUCTR2016-002027-29-IT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Alexion Pharmaceuticals Inc.
2017 Phase 3 EUCTR2016-002499-29-DE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-DE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Alexion Pharmaceuticals Incorporated
2019 Phase 3 EUCTR2016-002499-29-FR Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-SE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-IT Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-GB Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-ES Spain;United States
2017 Phase 3 EUCTR2016-002499-29-BE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-AT Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-SE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-ES Austria;Belgium;Czech Republic;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-BE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2016 Phase 3 EUCTR2016-002027-29-GB Australia;Austria;Belgium;Czech Republic;France;Germany;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2016 Phase 3 EUCTR2016-002027-29-AT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
- Phase 3 EUCTR2016-002027-29-CZ Australia;Austria;Belgium;Czech Republic;France;Germany;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
ANTI-C5 antibody
ALEXION PHARMACEUTICALS, INC.
2013 Phase 2 EUCTR2010-020326-18-FR Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020326-18-NL Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-BE Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-NL Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-GB Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-ES Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2011 - EUCTR2010-020310-28-DE Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020310-28-BE Australia;Austria;Belgium;Canada;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2010 - EUCTR2010-020326-18-GB Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020326-18-DE Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020310-28-AT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-SE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-NL Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006955-28-GB Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-DE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-AT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006954-17-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-SE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-NL Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-GB Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-DE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-AT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
- Phase 2 EUCTR2010-020310-28-FR Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
C5 INH MAB, SKY59, RO/CH7092230
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002475-35-IT Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002475-35-PL Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-HU Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-FR Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-DE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-BE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
CCX168
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
2015 Phase 2 EUCTR2014-004261-24-IT Italy
Mario Negri Institute for Pharmacological Research
2015 Phase 2 NCT02464891 Italy
Cemdisiran
Alnylam Pharmaceuticals
2017 Phase 2 NCT03303313 Bosnia and Herzegovina;Canada;Estonia;Georgia;Latvia;Lithuania;Macedonia, The Former Yugoslav Republic of;Moldova, Republic of;Serbia;Sweden
Alnylam Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2017-001082-24-SE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LV Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-LT Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
2017 Phase 2 EUCTR2017-001082-24-EE Albania;Bosnia and Herzegovina;Canada;Estonia;Georgia;India;Latvia;Lithuania;Macedonia, the former Yugoslav Republic of;Moldova, Republic of;Romania;Serbia;Sweden
IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
2019 Phase 2 EUCTR2018-004382-13-IT Italy
Mario Negri Institute for Pharmacological Research
2021 Phase 2 NCT03999840 Italy
Coversin
Akari Therapeutics Plc
2019 Phase 3 EUCTR2016-004129-18-LT Argentina;France;Germany;India;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
2018 Phase 3 EUCTR2016-004129-18-NL Argentina;Lithuania;Netherlands;Poland;United Kingdom
2017 Phase 3 EUCTR2016-004129-18-PL Argentina;France;Germany;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
Crovalimab
Camelia Sima
2022 Phase 3 JPRN-jRCT2031210061 BELGIUM;BRAZIL;CANADA;CHINA;FRANCE;GERMANY;HUNGARY;ISRAEL;ITALY;Japan;MEXICO;PERU;POLAND;SOUTH AFRICA;SPAIN;TURKEY;UNITED STATES
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002475-35-IT Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002475-35-PL Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-HU Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-FR Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-DE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-BE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Hoffmann-La Roche
2021 Phase 3 NCT04958265 Belgium;Brazil;Canada;China;France;Hungary;India;Israel;Italy;Japan;Mexico;Poland;South Africa;Spain;United States
2021 Phase 3 NCT04861259 Belgium;Brazil;Canada;China;France;Germany;Hungary;India;Israel;Italy;Japan;Mexico;New Zealand;Peru;Poland;South Africa;Spain;Turkey;United States
Mona D. Shah
2022 Phase 3 JPRN-jRCT2041210086 Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Eculizumab
ALEXION PHARMACEUTICALS
2011 - EUCTR2010-020310-28-IT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-IT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-IT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
ALEXION PHARMACEUTICALS INCORPORATED
- Phase 4 EUCTR2015-003135-35-IT Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
ALEXION PHARMACEUTICALS, INC.
2013 Phase 2 EUCTR2010-020326-18-FR Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020326-18-NL Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-ES Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-BE Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-NL Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-GB Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-ES Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2011 - EUCTR2010-020310-28-DE Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020310-28-BE Australia;Austria;Belgium;Canada;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2010 - EUCTR2010-020326-18-GB Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020326-18-DE Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020310-28-AT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-SE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-NL Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006955-28-GB Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-ES Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-DE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-AT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006954-17-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-SE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-NL Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-GB Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-DE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-AT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
- Phase 2 EUCTR2010-020310-28-FR Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP)
2023 Phase 3 EUCTR2022-002329-84-FR France
Alexion Pharmaceuticals
2015 - NCT02614898 Australia;Germany;United Kingdom;United States
2012 Phase 2 NCT01757431 Japan
2010 Phase 2 NCT01194973 Belgium;France;Germany;Italy;Spain;United Kingdom;United States
2010 Phase 2 NCT01193348 Australia;Belgium;Canada;France;Germany;Italy;Netherlands;United Kingdom;United States
2009 Phase 2 NCT00844844 Austria;Canada;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
2009 Phase 2 NCT00844545 Austria;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
2009 Phase 2 NCT00844428 Austria;Canada;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
2009 Phase 2 NCT00838513 Austria;Canada;France;Germany;Italy;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
Alexion Pharmaceuticals, Inc.
2023 Phase 3 NCT05876351 China
2016 Phase 4 EUCTR2015-003135-35-DE Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
Children's Hospital Medical Center, Cincinnati
2018 Phase 2 NCT03518203 United States
HOSPITAL UNIVERSITARI DE BELLVITGE- IDIBELL
2019 Phase 4 EUCTR2019-001619-21-ES Spain
Nantes University Hospital
2015 Phase 4 NCT02574403 France
Newcastle Upon Tyne Hospitals NHS Foundation Trust
2018 Phase 2 EUCTR2017-003916-37-GB United Kingdom
FC- and CDR-modified humanised monoclonal antibody against C5
ALEXION PHARMACEUTICALS INCORPORATED
2017 Phase 3 EUCTR2016-002027-29-IT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Alexion Pharmaceuticals Inc.
2017 Phase 3 EUCTR2016-002499-29-DE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals Incorporated
2019 Phase 3 EUCTR2016-002499-29-FR Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-SE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-IT Austria;Belgium;France;Germany;Italy;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-GB Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-ES Spain;United States
2017 Phase 3 EUCTR2016-002499-29-BE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-AT Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-SE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2017 Phase 3 EUCTR2016-002027-29-BE Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
2016 Phase 3 EUCTR2016-002027-29-AT Australia;Austria;Belgium;Czech Republic;France;Germany;Italy;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
- Phase 3 EUCTR2016-002027-29-CZ Australia;Austria;Belgium;Czech Republic;France;Germany;Japan;Korea, Republic of;Spain;Sweden;United Kingdom;United States
Iptacopan
Iwasaki Ryohei
2024 Phase 3 JPRN-jRCT2031230686 China;France;Germany;Italy;Japan;Spain;Turkey;United Kingdom;United Status
Novartis Pharma AG
2022 Phase 3 EUCTR2020-005186-13-SK Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-CZ Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-AT Austria;Brazil;China;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovenia;Taiwan;United Kingdom;United States
Novartis Pharmaceuticals
2024 Phase 3 NCT05935215 China;Japan;Spain;Turkey;United Kingdom
2022 Phase 3 NCT04889430 Austria;Brazil;China;Czechia;Greece;India;Japan;Korea, Republic of;Slovakia;Slovenia;Taiwan;United Kingdom;United States
Iptacopan hydrochloride
Novartis Pharma AG
2021 Phase 3 EUCTR2020-005186-13-SI Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
Iptcaopan 200 MG
Novartis Pharmaceuticals
2024 Phase 3 NCT05795140 Brazil;China;Czechia;India
LNP023
Novartis Pharma AG
2022 Phase 3 EUCTR2020-005186-13-SK Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-SI Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-CZ Austria;Brazil;China;Czech Republic;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovakia;Slovenia;Taiwan;United Kingdom;United States
2021 Phase 3 EUCTR2020-005186-13-AT Austria;Brazil;China;Czechia;Greece;Hungary;India;Japan;Korea, Republic of;Russian Federation;Slovenia;Taiwan;United Kingdom;United States
NM8074
NovelMed Therapeutics
2025 Phase 2 NCT05684159 -
OMS00620646, OMS620646, MASP-2 antibody
Omeros Corporation
2018 Phase 3 EUCTR2017-002057-11-PL Lithuania;Poland;Taiwan;United States
2017 Phase 3 EUCTR2017-002057-11-LT Lithuania;Poland;Taiwan;United States
OMS721
Omeros Corporation
2017 Phase 3 NCT03205995 United States
OMS721 100 MG/ML injection solution, OMS00620646, OMS620646, MASP-2 antibody
OMEROS CORPORATION
- Phase 2 EUCTR2014-001032-11-IT Belarus;Belgium;Bulgaria;Czechia;Germany;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Sweden;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
Omeros Corporation
2014 Phase 2 EUCTR2014-001032-11-PL Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
2014 Phase 2 EUCTR2014-001032-11-LT Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
2014 Phase 2 EUCTR2014-001032-11-BE Belarus;Belgium;Bulgaria;Germany;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Switzerland;Taiwan;Thailand;Turkey;United Kingdom;United States
OMS721 185 MG/ML injection solution, OMS00620646, OMS620646, MASP-2 antibody
Omeros Corporation
2014 Phase 2 EUCTR2014-001032-11-PL Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
2014 Phase 2 EUCTR2014-001032-11-LT Belgium;Bulgaria;Hong Kong;Italy;Lithuania;Malaysia;New Zealand;Poland;Singapore;Taiwan;Thailand;United States
OMS721 drug product 185 MG/ML
Omeros Corporation
2018 Phase 3 EUCTR2017-002057-11-PL Lithuania;Poland;Taiwan;United States
2017 Phase 3 EUCTR2017-002057-11-LT Lithuania;Poland;Taiwan;United States
Ravulizumab
Alexion
2017 Phase 3 NCT02949128 Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals Inc.
2017 Phase 3 EUCTR2016-002499-29-DE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals Incorporated
2017 Phase 3 EUCTR2016-002499-29-SE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-GB Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-BE Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
2017 Phase 3 EUCTR2016-002499-29-AT Australia;Austria;Belgium;Canada;France;Germany;Italy;Japan;Korea, Republic of;Russian Federation;Spain;Sweden;Taiwan;United Kingdom;United States
Alexion Pharmaceuticals, Inc.
2017 Phase 3 NCT03131219 Belgium;Germany;Italy;Japan;Korea, Republic of;Spain;United Kingdom;United States
RO7112689/F03-01
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
RO7112689/F03-10
F. HOFFMANN - LA ROCHE LTD.
2021 Phase 3 EUCTR2020-002475-35-IT Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002437-15-IT Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002475-35-PL Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-HU Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-FR Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-DE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
2021 Phase 3 EUCTR2020-002475-35-BE Australia;Belgium;Brazil;Canada;China;Czechia;France;Germany;Hungary;Israel;Italy;Korea, Republic of;Luxembourg;Mexico;Peru;Poland;South Africa;Spain;Turkey;United Kingdom;United States
F.Hoffmann-La Roche Ltd
2022 Phase 3 EUCTR2020-002437-15-HU Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2022 Phase 3 EUCTR2020-002437-15-BE Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
2021 Phase 3 EUCTR2020-002437-15-PL Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
Roche Farma S. A. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
2021 Phase 3 EUCTR2020-002437-15-ES Belgium;Brazil;Canada;China;France;Hungary;Israel;Italy;Japan;Poland;South Africa;Spain;United States
RVA576
Akari Therapeutics Plc
2019 Phase 3 EUCTR2016-004129-18-LT Argentina;France;Germany;India;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
2018 Phase 3 EUCTR2016-004129-18-NL Argentina;Lithuania;Netherlands;Poland;United Kingdom
2017 Phase 3 EUCTR2016-004129-18-PL Argentina;France;Germany;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
2017 Phase 3 EUCTR2016-004129-18-GB Argentina;France;Germany;Kazakhstan;Lithuania;Netherlands;Poland;Sri Lanka;United Kingdom
Solaris
Newcastle Upon Tyne Hospitals NHS Foundation Trust
2018 Phase 2 EUCTR2017-003916-37-GB United Kingdom
Soliris
ALEXION PHARMACEUTICALS
2011 - EUCTR2010-020326-18-IT Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-IT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-IT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-IT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
ALEXION PHARMACEUTICALS INCORPORATED
- Phase 4 EUCTR2015-003135-35-IT Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
ALEXION PHARMACEUTICALS, INC.
2013 Phase 2 EUCTR2010-020326-18-FR Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020326-18-NL Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020326-18-BE Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-NL Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-GB Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2011 Phase 2 EUCTR2010-020310-28-ES Australia;Austria;Belgium;Canada;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2011 - EUCTR2010-020310-28-DE Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2011 - EUCTR2010-020310-28-BE Australia;Austria;Belgium;Canada;Germany;Italy;Netherlands;Spain;United Kingdom;United States
2010 - EUCTR2010-020326-18-GB Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020326-18-DE Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2010 - EUCTR2010-020310-28-AT Austria;Belgium;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-SE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-NL Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006955-28-GB Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-DE Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006955-28-AT Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006954-17-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-SE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-NL Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-GB Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006953-41-DE Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006953-41-AT Austria;Germany;Italy;Netherlands;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-SE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-NL Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-GB Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 Phase 2 EUCTR2008-006952-23-FR Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-DE Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-AT Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
- Phase 2 EUCTR2010-020310-28-FR Austria;Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
Alexion Pharmaceuticals, Inc.
2016 Phase 4 EUCTR2015-003135-35-DE Australia;Belgium;Canada;Czech Republic;Germany;Israel;Italy;Norway;Poland;Russian Federation;Spain;United Arab Emirates;United Kingdom;United States
HOSPITAL UNIVERSITARI DE BELLVITGE- IDIBELL
2019 Phase 4 EUCTR2019-001619-21-ES Spain
Soliris 300 MG concentrado para solucióN para perfusióN
ALEXION PHARMACEUTICALS, INC.
2011 Phase 2 EUCTR2010-020326-18-ES Belgium;France;Germany;Italy;Netherlands;Spain;United Kingdom
2009 - EUCTR2008-006955-28-ES Austria;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006954-17-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
2009 - EUCTR2008-006952-23-ES Austria;France;Germany;Italy;Netherlands;Spain;Sweden;United Kingdom
Soliris 300 MG solution à diluer pour perfusion
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP)
2023 Phase 3 EUCTR2022-002329-84-FR France
Ultomiris
Alexion Pharmaceuticals, Inc.
2024 - NCT06312644 United States