152. PCDH19関連症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 11 / 薬物数 : 4 - (DrugBank : 1) / 標的遺伝子数 : 16 - 標的パスウェイ数 : 8
薬物、開発者（Primary Sponsor）、臨床試験情報（症例登録開始年（Enrollment year）、フェーズ、ID、実施国）
CCD 1042, MD 9150000, mepalon 1042, SPT316
Marinus Pharmaceuticals, Inc
2019 Phase 3 EUCTR2018-004496-12-IT Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
Marinus Pharmaceuticals, Inc.
2019 Phase 3 EUCTR2018-004496-12-FR Australia;France;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2015 - EUCTR2015-001324-36-IT Italy;United States
- Phase 3 EUCTR2018-004496-12-DK Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
CCD 1042, MD 9150000, mepalon 1042, SPT3162
Marinus Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2018-004496-12-HU Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2020 Phase 3 EUCTR2018-004496-12-GB Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
2019 Phase 2 EUCTR2018-004496-12-NL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
- Phase 2 EUCTR2018-004496-12-PL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;Poland;Spain;United Kingdom;United States
Exome and/or whole genome sequencing
Boston Children's Hospital
2010 - NCT01858285 United States
Ganaxolone
Marinus Pharmaceuticals
2019 Phase 2 NCT03865732 Australia;France;Hungary;Italy;Netherlands;Poland;United States
2015 Phase 2 NCT02358538 Italy;United States
Marinus Pharmaceuticals, Inc
2019 Phase 3 EUCTR2018-004496-12-IT Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
Marinus Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2018-004496-12-HU Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2020 Phase 3 EUCTR2018-004496-12-GB Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
2019 Phase 2 EUCTR2018-004496-12-NL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2019 Phase 3 EUCTR2018-004496-12-FR Australia;France;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2015 - EUCTR2015-001324-36-IT Italy;United States
- Phase 2 EUCTR2018-004496-12-PL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;Poland;Spain;United Kingdom;United States
- Phase 3 EUCTR2018-004496-12-DK Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
Marinus Pharmaceuticals, Inc
2019 Phase 3 EUCTR2018-004496-12-IT Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
Marinus Pharmaceuticals, Inc.
2019 Phase 3 EUCTR2018-004496-12-FR Australia;France;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2015 - EUCTR2015-001324-36-IT Italy;United States
- Phase 3 EUCTR2018-004496-12-DK Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
CCD 1042, MD 9150000, mepalon 1042, SPT3162
Marinus Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2018-004496-12-HU Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2020 Phase 3 EUCTR2018-004496-12-GB Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
2019 Phase 2 EUCTR2018-004496-12-NL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
- Phase 2 EUCTR2018-004496-12-PL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;Poland;Spain;United Kingdom;United States
Exome and/or whole genome sequencing
Boston Children's Hospital
2010 - NCT01858285 United States
Ganaxolone
Marinus Pharmaceuticals
2019 Phase 2 NCT03865732 Australia;France;Hungary;Italy;Netherlands;Poland;United States
2015 Phase 2 NCT02358538 Italy;United States
Marinus Pharmaceuticals, Inc
2019 Phase 3 EUCTR2018-004496-12-IT Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
Marinus Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2018-004496-12-HU Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2020 Phase 3 EUCTR2018-004496-12-GB Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;United Kingdom;United States
2019 Phase 2 EUCTR2018-004496-12-NL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2019 Phase 3 EUCTR2018-004496-12-FR Australia;France;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States
2015 - EUCTR2015-001324-36-IT Italy;United States
- Phase 2 EUCTR2018-004496-12-PL Australia;Belgium;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;Poland;Spain;United Kingdom;United States
- Phase 3 EUCTR2018-004496-12-DK Australia;Belgium;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Spain;United Kingdom;United States