167. マルファン症候群/ロイス・ディーツ症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 23 / 薬物数 : 31 - (DrugBank : 8) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 51
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
Aliskiren
Samsung Medical Center
2010 Phase 3 NCT01715207 Korea, Republic of
Aprovel
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Royal Brompton and Harefield NHS Foundation Trust
2010 Phase 3 EUCTR2010-019302-16-GB United Kingdom
Atenolol
Brigham and Women's Hospital
2007 Phase 3 NCT00723801 United States
Cardiff University
2006 Phase 4 NCT01295047 United Kingdom
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Forteza, Albert, M.D.
2008 Phase 3 NCT01145612 Spain
New England Research Institutes
2007 Phase 3 NCT00429364 Belgium;Canada;United States
Samsung Medical Center
2010 Phase 3 NCT01715207 Korea, Republic of
University Hospital Gent
2006 - EUCTR2006-003991-37-BE Belgium
University of British Columbia
2008 Phase 2 NCT00593710 Canada
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Atenolol or propranolol
National Taiwan University Hospital
2007 Phase 2 NCT00651235 Taiwan
Blokium 50 MG comprimidos
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Blood samples
Hospices Civils de Lyon
2022 - NCT05472519 France
Bloodsampling
University Hospital, Antwerp
2020 - NCT06257004 Belgium
Collection OF samples OF blood and urine
University Hospital, Toulouse
2022 - NCT04970459 France
Coozar
University Hospital Ghent
2009 - EUCTR2007-005862-10-BE Belgium
Coversyl
Bayside Health
2004 Phase 3 NCT00485368 -
Cardiff University
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Cozaar
University Hospital Ghent
2009 - EUCTR2007-005862-10-BE Belgium
Cozaar 50
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Cozaar inicio 12,5 MG comprimidos recubiertos CON pelicula
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Doxycycline 100-200MG capsules daily FOR 6 months
University of Oxford
2013 Phase 2 NCT01949233 United Kingdom
Doxycycline hyclate PH.EUR
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Irbesartan
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Royal Brompton and Harefield NHS Foundation Trust
2010 Phase 3 EUCTR2010-019302-16-GB United Kingdom
Irbesartan 150-300MG capsules daily FOR 6 months
University of Oxford
2013 Phase 2 NCT01949233 United Kingdom
Lobivon*28CPR 5MG
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
Lortaan*28CPR RIV DIV 50MG
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
Losartan
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00763893 France
Brigham and Women's Hospital
2007 Phase 3 NCT00723801 United States
Forteza, Albert, M.D.
2008 Phase 3 NCT01145612 Spain
National Taiwan University Hospital
2007 Phase 2 NCT00651235 Taiwan
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
University Hospital, Ghent
2009 Phase 3 NCT00782327 Belgium
University of British Columbia
2008 Phase 2 NCT00593710 Canada
Losartan and nebivolol
IRCCS Policlinico S. Matteo
2008 Phase 3 NCT00683124 Italy
Losartan potassium
New England Research Institutes
2007 Phase 3 NCT00429364 Belgium;Canada;United States
University Hospital Gent
2006 - EUCTR2006-003991-37-BE Belgium
University Hospital Ghent
2009 - EUCTR2007-005862-10-BE Belgium
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Nebivolol
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
Perindopril
Bayside Health
2004 Phase 3 NCT00485368 -
Cardiff University
2006 Phase 4 NCT01295047 United Kingdom
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Valsacor
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Valsartanum 40 MG / placebo 1
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Valsartanum 80 MG / placebo 2
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Valzek
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Verapamil
Cardiff University
2006 Phase 4 NCT01295047 United Kingdom
Verapamil SR
Cardiff University
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Vibrox 100MG capsules
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Samsung Medical Center
2010 Phase 3 NCT01715207 Korea, Republic of
Aprovel
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Royal Brompton and Harefield NHS Foundation Trust
2010 Phase 3 EUCTR2010-019302-16-GB United Kingdom
Atenolol
Brigham and Women's Hospital
2007 Phase 3 NCT00723801 United States
Cardiff University
2006 Phase 4 NCT01295047 United Kingdom
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Forteza, Albert, M.D.
2008 Phase 3 NCT01145612 Spain
New England Research Institutes
2007 Phase 3 NCT00429364 Belgium;Canada;United States
Samsung Medical Center
2010 Phase 3 NCT01715207 Korea, Republic of
University Hospital Gent
2006 - EUCTR2006-003991-37-BE Belgium
University of British Columbia
2008 Phase 2 NCT00593710 Canada
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Atenolol or propranolol
National Taiwan University Hospital
2007 Phase 2 NCT00651235 Taiwan
Blokium 50 MG comprimidos
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Blood samples
Hospices Civils de Lyon
2022 - NCT05472519 France
Bloodsampling
University Hospital, Antwerp
2020 - NCT06257004 Belgium
Collection OF samples OF blood and urine
University Hospital, Toulouse
2022 - NCT04970459 France
Coozar
University Hospital Ghent
2009 - EUCTR2007-005862-10-BE Belgium
Coversyl
Bayside Health
2004 Phase 3 NCT00485368 -
Cardiff University
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Cozaar
University Hospital Ghent
2009 - EUCTR2007-005862-10-BE Belgium
Cozaar 50
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Cozaar inicio 12,5 MG comprimidos recubiertos CON pelicula
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Doxycycline 100-200MG capsules daily FOR 6 months
University of Oxford
2013 Phase 2 NCT01949233 United Kingdom
Doxycycline hyclate PH.EUR
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Irbesartan
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom
Royal Brompton and Harefield NHS Foundation Trust
2010 Phase 3 EUCTR2010-019302-16-GB United Kingdom
Irbesartan 150-300MG capsules daily FOR 6 months
University of Oxford
2013 Phase 2 NCT01949233 United Kingdom
Lobivon*28CPR 5MG
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
Lortaan*28CPR RIV DIV 50MG
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
Losartan
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00763893 France
Brigham and Women's Hospital
2007 Phase 3 NCT00723801 United States
Forteza, Albert, M.D.
2008 Phase 3 NCT01145612 Spain
National Taiwan University Hospital
2007 Phase 2 NCT00651235 Taiwan
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
University Hospital, Ghent
2009 Phase 3 NCT00782327 Belgium
University of British Columbia
2008 Phase 2 NCT00593710 Canada
Losartan and nebivolol
IRCCS Policlinico S. Matteo
2008 Phase 3 NCT00683124 Italy
Losartan potassium
New England Research Institutes
2007 Phase 3 NCT00429364 Belgium;Canada;United States
University Hospital Gent
2006 - EUCTR2006-003991-37-BE Belgium
University Hospital Ghent
2009 - EUCTR2007-005862-10-BE Belgium
alberto forteza
2008 - EUCTR2007-001125-97-ES Spain
Nebivolol
OSPEDALE POLICLINICO S. MATTEO
2008 Phase 3 EUCTR2008-001462-81-IT Italy
Perindopril
Bayside Health
2004 Phase 3 NCT00485368 -
Cardiff University
2006 Phase 4 NCT01295047 United Kingdom
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Valsacor
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Valsartanum 40 MG / placebo 1
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Valsartanum 80 MG / placebo 2
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Valzek
Medical University of Gdansk
2023 Phase 3 EUCTR2022-000513-14-PL Poland
Verapamil
Cardiff University
2006 Phase 4 NCT01295047 United Kingdom
Verapamil SR
Cardiff University
2005 Phase 4 EUCTR2005-000749-13-GB United Kingdom
Vibrox 100MG capsules
Clinical Trials and Research Governance
2013 Phase 2 EUCTR2010-023612-14-GB United Kingdom