195. ヌーナン症候群 Disease details / Clinical trials / Drug dev / DR info


臨床試験数 : 38 / 薬物数 : 27 - (DrugBank : 7) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 96

薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
Blood and urine sampling
   University Hospital, Toulouse
      2022   -   NCT05202210   France
Blood sample
   Assistance Publique - Hôpitaux de Paris
      2024   -   NCT06147414   France
Growth hormone
   Fujioka Koichi
      2022   Phase 3   JPRN-jRCT2031220263   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russia;Saudi Arabia;Serbia;Slovenia;South Africa;South Korea;Spain;Switzerland
Human growth hormone
   BioMarin Pharmaceutical
      2024   Phase 2   NCT06668805   France;Spain;United States
   Shallghai Children's Medical Center
      2022   Phase 4   ChiCTR2200065823   China
Lamotrigin beta
   Technische Universität München, Fakultät für Medizin
      2018   Phase 2   EUCTR2016-005022-10-DE   Germany
Lovastatin
   Technische Universität München, Fakultät für Medizin
      2018   Phase 2   EUCTR2016-005022-10-DE   Germany
Maxomat ®, biosynthetic growth hormone
   Sanofi
      1997   Phase 3   NCT00452725   France
MEK162
   Array Biopharma, now a wholly owned subsidiary of Pfizer
      2012   Phase 2   NCT01556568   United Kingdom;United States
   Novartis Pharma Services AG
      2012   -   EUCTR2011-003392-10-GB   United Kingdom;United States
Norditropin
   Fujioka Koichi
      2022   Phase 3   JPRN-jRCT2031220263   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russia;Saudi Arabia;Serbia;Slovenia;South Africa;South Korea;Spain;Switzerland
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
   Novo Nordisk A/S
      2023   Phase 3   EUCTR2021-005607-13-LT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   NCT05330325   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   -   NCT05308927   France
      2022   Phase 3   EUCTR2021-005607-13-FR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Norditropin 24 IU
   Novo Nordisk A/S
      2005   -   EUCTR2005-000042-37-SE   Sweden
Norditropin flexpro 10 MG/1.5 ML, solution FOR injection IN PRE-filled PEN
   Novo Nordisk A/S
      2023   Phase 3   EUCTR2021-005607-13-PT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-SI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-NL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-LV   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-IE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-HR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-FI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-DE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BG   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-PL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-GR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Norditropin simplexx
   Novo Nordisk A/S
      2005   -   EUCTR2005-000042-37-SE   Sweden
Oral glucose tolerance test
   University Hospital, Toulouse
      2015   -   NCT02383316   France
Polyethylene glycol
   Shallghai Children's Medical Center
      2022   Phase 4   ChiCTR2200065823   China
Rhigf-1/rhigfbp-3
   Insmed Incorporated
      2006   Phase 2   NCT00351221   United States
Simvastatin
   University Hospital Toulouse
      2016   Phase 3   EUCTR2016-000647-14-FR   France
   University Hospital, Toulouse
      2017   Phase 3   NCT02713945   France
Sogroya 10 MG/1.5 ML solution FOR injection IN PRE-filled PEN
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
   Novo Nordisk A/S
      2023   Phase 3   EUCTR2021-005607-13-PT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-SI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-NL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-LV   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-IE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-HR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-FI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-DE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BG   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-PL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-GR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Sogroya 10 MG/1.5 ML soluzione PER iniezione IN penna PRE-riempita
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Sogroya 5 MG/1.5 ML solution FOR injection IN PRE-filled PEN
   Novo Nordisk A/S
      2022   Phase 3   EUCTR2021-005607-13-BE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Somapacitan
   Fujioka Koichi
      2022   Phase 3   JPRN-jRCT2031220263   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russia;Saudi Arabia;Serbia;Slovenia;South Africa;South Korea;Spain;Switzerland
   Novo Nordisk A/S
      2023   Phase 3   NCT05723835   Korea, Republic of;Malaysia;Netherlands;Poland;Spain;United States
      2023   Phase 3   EUCTR2021-005607-13-LT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   NCT05330325   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-FR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Somapacitan 15 MG/1.5 ML PDS290
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
   Novo Nordisk A/S
      2023   Phase 3   EUCTR2021-005607-13-PT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-SI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-NL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-LV   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-IE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-HR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-FI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-DE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BG   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-PL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-GR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Somapacitan 5 MG/1.5 ML PDS290
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
   Novo Nordisk A/S
      2023   Phase 3   EUCTR2021-005607-13-PT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-SI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-NL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-LV   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-IE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-HR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-FI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-DE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BG   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-PL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-GR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Somatropin
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
   Novo Nordisk A/S
      2023   Phase 3   EUCTR2021-005607-13-PT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-SI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-NL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-LV   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-IE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-HR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-FI   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-DE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BG   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2022   Phase 3   EUCTR2021-005607-13-BE   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      2018   -   NCT03435627   Japan
      2013   Phase 3   NCT01927861   Japan
      2008   Phase 3   NCT01529944   Sweden
      2006   -   NCT00960128   Argentina;Belgium;Brazil;Czech Republic;Czechia;Denmark;Finland;Former Serbia and Montenegro;France;Germany;Hungary;Ireland;Israel;Italy;Lithuania;Luxembourg;Netherlands;Norway;Russian Federation;Saudi Arabia;Serbia;Slovenia;Spain;Sweden;Switzerland;United Kingdom
      2005   -   EUCTR2005-000042-37-SE   Sweden
      1990   Phase 3   NCT01529840   Sweden
      -   Phase 3   EUCTR2021-005607-13-PL   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
      -   Phase 3   EUCTR2021-005607-13-GR   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;European Union;Finland;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Somatropina
   NOVO NORDISK. S.P.A.
      2022   Phase 3   EUCTR2021-005607-13-IT   Austria;Belgium;Brazil;Bulgaria;Canada;China;Croatia;Finland;France;Germany;Greece;India;Ireland;Israel;Italy;Japan;Korea, Republic of;Latvia;Lithuania;Malaysia;Mexico;Netherlands;Poland;Portugal;Russian Federation;Saudi Arabia;Serbia;Slovenia;South Africa;Spain;Switzerland;Thailand;United Kingdom;United States
Standard therapy
   Medical University of Warsaw
      2024   Phase 2   NCT06555237   Poland
Trametinib tablet
   Medical University of Warsaw
      2024   Phase 2   NCT06555237   Poland
Vosoritide injection
   BioMarin Pharmaceutical
      2024   Phase 2   NCT06668805   France;Spain;United States