25. 進行性多巣性白質脳症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 28 / 薬物数 : 31 - (DrugBank : 20) / 標的遺伝子数 : 7 - 標的パスウェイ数 : 35
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
111jc101
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom
89 ZR-DF-crefmirlimab
National Institute of Neurological Disorders and Stroke (NINDS)
2023 Phase 1 NCT05849467 United States
Brain MRI
University Hospital, Toulouse
2021 - NCT04453917 France
CE-VST01-JC
Cellevolve Bio Inc
2023 Phase 2 NCT05541549 -
Cidofovir
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States
Collection OF blood and urine
University Hospital, Toulouse
2021 - NCT04453917 France
CYT107
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States
Cytarabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Didanosine
Bristol-Myers Squibb
1997 - NCT00002274 United States
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Enfuvirtide
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France
Filgrastim
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Interferon ALFA-2B
University of Miami
1997 - NCT00002270 United States
Lariam
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom
Mefloquine
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom
Biogen
2009 Phase 1/Phase 2 NCT00746941 Australia;Brazil;France;Germany;Italy;Puerto Rico;Spain;United Kingdom;United States
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom
Department of Neurology, Shimane University Hospital
2016 - JPRN-UMIN000022151 Japan
Nagoya City University
2016 - JPRN-UMIN000023752 Japan
Methylprednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States
Biogen Idec
2010 - EUCTR2010-020369-26-DE Germany
Natalizumab
Biogen
2019 - NCT05236777 Czechia
Neurological evaluation
University Hospital, Toulouse
2021 - NCT04453917 France
NT-I7
National Institute of Neurological Disorders and Stroke (NINDS)
2021 Early Phase 1 NCT04781309 United States
Pembrolizumab
First Affiliated Hospital of Zhejiang University
2019 Phase 2 NCT04091932 China
Pembrolizumab, 25 MG/ML solution FOR intravenous (IV) injection
Assistance Publique - Hôpitaux de Paris
2024 Phase 2/Phase 3 NCT06276504 France
Prednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States
Biogen Idec
2010 - EUCTR2010-020369-26-DE Germany
Probenecid
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States
Pyvst
National Institute of Neurological Disorders and Stroke (NINDS)
2016 Early Phase 1 NCT02694783 United States
Recombinant human interleukin-7
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States
Spinal TAP
University Hospital, Toulouse
2021 - NCT04453917 France
Tenofovir-emtricitabine
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France
Teriflunomide
Providence Health & Services
2013 Phase 4 NCT01970410 United States
Topotecan
SmithKline Beecham
1996 Phase 2 NCT00002395 United States
Tysabri
Biogen
2017 - NCT03399981 United States
Zalcitabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Zidovudine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
University of Miami
1997 - NCT00002270 United States
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom
89 ZR-DF-crefmirlimab
National Institute of Neurological Disorders and Stroke (NINDS)
2023 Phase 1 NCT05849467 United States
Brain MRI
University Hospital, Toulouse
2021 - NCT04453917 France
CE-VST01-JC
Cellevolve Bio Inc
2023 Phase 2 NCT05541549 -
Cidofovir
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States
Collection OF blood and urine
University Hospital, Toulouse
2021 - NCT04453917 France
CYT107
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States
Cytarabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Didanosine
Bristol-Myers Squibb
1997 - NCT00002274 United States
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Enfuvirtide
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France
Filgrastim
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Interferon ALFA-2B
University of Miami
1997 - NCT00002270 United States
Lariam
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom
Mefloquine
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom
Biogen
2009 Phase 1/Phase 2 NCT00746941 Australia;Brazil;France;Germany;Italy;Puerto Rico;Spain;United Kingdom;United States
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom
2008 Phase 2 EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom
Department of Neurology, Shimane University Hospital
2016 - JPRN-UMIN000022151 Japan
Nagoya City University
2016 - JPRN-UMIN000023752 Japan
Methylprednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States
Biogen Idec
2010 - EUCTR2010-020369-26-DE Germany
Natalizumab
Biogen
2019 - NCT05236777 Czechia
Neurological evaluation
University Hospital, Toulouse
2021 - NCT04453917 France
NT-I7
National Institute of Neurological Disorders and Stroke (NINDS)
2021 Early Phase 1 NCT04781309 United States
Pembrolizumab
First Affiliated Hospital of Zhejiang University
2019 Phase 2 NCT04091932 China
Pembrolizumab, 25 MG/ML solution FOR intravenous (IV) injection
Assistance Publique - Hôpitaux de Paris
2024 Phase 2/Phase 3 NCT06276504 France
Prednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States
Biogen Idec
2010 - EUCTR2010-020369-26-DE Germany
Probenecid
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States
Pyvst
National Institute of Neurological Disorders and Stroke (NINDS)
2016 Early Phase 1 NCT02694783 United States
Recombinant human interleukin-7
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States
Spinal TAP
University Hospital, Toulouse
2021 - NCT04453917 France
Tenofovir-emtricitabine
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France
Teriflunomide
Providence Health & Services
2013 Phase 4 NCT01970410 United States
Topotecan
SmithKline Beecham
1996 Phase 2 NCT00002395 United States
Tysabri
Biogen
2017 - NCT03399981 United States
Zalcitabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
Zidovudine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States
University of Miami
1997 - NCT00002270 United States