269. 化膿性無菌性関節炎・壊疽性膿皮症・アクネ症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 32 / 薬物数 : 32 - (DrugBank : 16) / 標的遺伝子数 : 17 - 標的パスウェイ数 : 106
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
Adalimumab
AbbVie
2017 Phase 3 NCT03311464 Japan
Wake Forest University Health Sciences
2007 Phase 2 NCT00690846 United States
ANTI-(complement C5A) IGG4 chimeric monoclonal antibody
InflaRx GmbH
2020 Phase 2 EUCTR2020-003273-21-PL Poland;United States
APD334
Arena Pharmaceuticals
2017 Phase 2 NCT03072953 Australia;New Zealand
Baricitinib
Oregon Health and Science University
2023 Phase 2 NCT04901325 United States
Canakinumab
IRCCS ISTITUTO GIANNINA GASLINI
2023 Phase 3 EUCTR2021-005754-28-IT Italy
University of Zurich
2011 Phase 2 NCT01302795 Switzerland
Ciclosporin
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Cosentyx
Technische Universität München, School of Medicine, represented by Dean
2015 Phase 2;Phase 3 EUCTR2015-000762-65-DE Germany
Dehydrated human amnion/chorion membrane
Louisiana State University Health Sciences Center in New Orleans
2021 Phase 4 NCT05120726 United States
Deucravacitinib
Dartmouth-Hitchcock Medical Center
2025 Early Phase 1 NCT05821374 United States
EU/1/14/980/002
Technische Universität München, School of Medicine, represented by Dean
2015 Phase 2;Phase 3 EUCTR2015-000762-65-DE Germany
EU/1/14/980/003
Technische Universität München, School of Medicine, represented by Dean
2015 Phase 2;Phase 3 EUCTR2015-000762-65-DE Germany
Gevokizumab
MedDerm Associates
2015 Phase 3 NCT02366260 United States
XOMA (US) LLC
2014 Phase 3 NCT02318914 Australia;Canada;United States
2013 Phase 2 NCT01882504 United States
Gevokizumab OPEN-label
XOMA (US) LLC
2014 Phase 3 NCT02326740 Australia;Canada;United States
2014 Phase 3 NCT02315417 United States
Guselkumab
Oregon Health and Science University
2025 Phase 2 NCT06563323 United States
Humira
Wright State University
2009 Phase 2 NCT00730717 United States
Hyperbaric oxygen
Erasmus Medical Center
2022 Phase 3 NCT05343754 Netherlands
IFX-1
InflaRx GmbH
2020 Phase 2 EUCTR2020-003273-21-PL Poland;United States
Infliximab
University Hospitals Cleveland Medical Center
2008 - NCT00791557 United States
Ixekizumab
Ohio State University
2017 Phase 2 NCT03137160 United States
Monoclonal antibody (MAB) SB24M
SWISS BIOPHARMA MED GmbH
2021 Early Phase 1 NCT04895566 Belarus;Latvia
Neoral oral solution
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Neoral soft gelatin capsules
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Platelet rich plasma therapy
Ohio State University
2024 - NCT05984654 United States
Prednisolone
Boehringer Ingelheim
2025 Phase 3 NCT06624670 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Finland;France;Germany;Hungary;Italy;Japan;Malaysia;Norway;Poland;Portugal;Puerto Rico;Spain;Sweden;Switzerland;United States
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Prednisone
Boehringer Ingelheim
2025 Phase 3 NCT06624670 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Finland;France;Germany;Hungary;Italy;Japan;Malaysia;Norway;Poland;Portugal;Puerto Rico;Spain;Sweden;Switzerland;United States
Secukinumab
Technical University of Munich
2016 Phase 1/Phase 2 NCT02733094 Germany
Secukinumab 150 MG (2 injections PER dose
Wake Forest University Health Sciences
2021 Phase 2 NCT04274166 United States
Spesolimab
Boehringer Ingelheim
2025 Phase 3 NCT06624670 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Finland;France;Germany;Hungary;Italy;Japan;Malaysia;Norway;Poland;Portugal;Puerto Rico;Spain;Sweden;Switzerland;United States
Icahn School of Medicine at Mount Sinai
2023 Phase 2 NCT06092216 United States
Stelara
University Hospital Tübingen
2012 Phase 2 EUCTR2011-002920-41-DE Germany
Ustekinumab
University Hospital Tübingen
2012 Phase 2 EUCTR2011-002920-41-DE Germany
Vilobelimab
InflaRx GmbH
2023 Phase 3 NCT05964413 Australia;Belgium;France;Germany;Hungary;Italy;Poland;Spain;Switzerland;United States
2019 Phase 2 NCT03971643 Canada;Poland;United States
Xilonix
Janssen Research & Development, LLC
2014 Phase 2 NCT01965613 United States
AbbVie
2017 Phase 3 NCT03311464 Japan
Wake Forest University Health Sciences
2007 Phase 2 NCT00690846 United States
ANTI-(complement C5A) IGG4 chimeric monoclonal antibody
InflaRx GmbH
2020 Phase 2 EUCTR2020-003273-21-PL Poland;United States
APD334
Arena Pharmaceuticals
2017 Phase 2 NCT03072953 Australia;New Zealand
Baricitinib
Oregon Health and Science University
2023 Phase 2 NCT04901325 United States
Canakinumab
IRCCS ISTITUTO GIANNINA GASLINI
2023 Phase 3 EUCTR2021-005754-28-IT Italy
University of Zurich
2011 Phase 2 NCT01302795 Switzerland
Ciclosporin
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Cosentyx
Technische Universität München, School of Medicine, represented by Dean
2015 Phase 2;Phase 3 EUCTR2015-000762-65-DE Germany
Dehydrated human amnion/chorion membrane
Louisiana State University Health Sciences Center in New Orleans
2021 Phase 4 NCT05120726 United States
Deucravacitinib
Dartmouth-Hitchcock Medical Center
2025 Early Phase 1 NCT05821374 United States
EU/1/14/980/002
Technische Universität München, School of Medicine, represented by Dean
2015 Phase 2;Phase 3 EUCTR2015-000762-65-DE Germany
EU/1/14/980/003
Technische Universität München, School of Medicine, represented by Dean
2015 Phase 2;Phase 3 EUCTR2015-000762-65-DE Germany
Gevokizumab
MedDerm Associates
2015 Phase 3 NCT02366260 United States
XOMA (US) LLC
2014 Phase 3 NCT02318914 Australia;Canada;United States
2013 Phase 2 NCT01882504 United States
Gevokizumab OPEN-label
XOMA (US) LLC
2014 Phase 3 NCT02326740 Australia;Canada;United States
2014 Phase 3 NCT02315417 United States
Guselkumab
Oregon Health and Science University
2025 Phase 2 NCT06563323 United States
Humira
Wright State University
2009 Phase 2 NCT00730717 United States
Hyperbaric oxygen
Erasmus Medical Center
2022 Phase 3 NCT05343754 Netherlands
IFX-1
InflaRx GmbH
2020 Phase 2 EUCTR2020-003273-21-PL Poland;United States
Infliximab
University Hospitals Cleveland Medical Center
2008 - NCT00791557 United States
Ixekizumab
Ohio State University
2017 Phase 2 NCT03137160 United States
Monoclonal antibody (MAB) SB24M
SWISS BIOPHARMA MED GmbH
2021 Early Phase 1 NCT04895566 Belarus;Latvia
Neoral oral solution
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Neoral soft gelatin capsules
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Platelet rich plasma therapy
Ohio State University
2024 - NCT05984654 United States
Prednisolone
Boehringer Ingelheim
2025 Phase 3 NCT06624670 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Finland;France;Germany;Hungary;Italy;Japan;Malaysia;Norway;Poland;Portugal;Puerto Rico;Spain;Sweden;Switzerland;United States
Nottingham University Hospitals NHS Trust
2010 - EUCTR2008-008291-14-IE Ireland;United Kingdom
2009 Phase 4 EUCTR2008-008291-14-GB Ireland;United Kingdom
Prednisone
Boehringer Ingelheim
2025 Phase 3 NCT06624670 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Finland;France;Germany;Hungary;Italy;Japan;Malaysia;Norway;Poland;Portugal;Puerto Rico;Spain;Sweden;Switzerland;United States
Secukinumab
Technical University of Munich
2016 Phase 1/Phase 2 NCT02733094 Germany
Secukinumab 150 MG (2 injections PER dose
Wake Forest University Health Sciences
2021 Phase 2 NCT04274166 United States
Spesolimab
Boehringer Ingelheim
2025 Phase 3 NCT06624670 Argentina;Australia;Austria;Belgium;Brazil;Canada;China;Finland;France;Germany;Hungary;Italy;Japan;Malaysia;Norway;Poland;Portugal;Puerto Rico;Spain;Sweden;Switzerland;United States
Icahn School of Medicine at Mount Sinai
2023 Phase 2 NCT06092216 United States
Stelara
University Hospital Tübingen
2012 Phase 2 EUCTR2011-002920-41-DE Germany
Ustekinumab
University Hospital Tübingen
2012 Phase 2 EUCTR2011-002920-41-DE Germany
Vilobelimab
InflaRx GmbH
2023 Phase 3 NCT05964413 Australia;Belgium;France;Germany;Hungary;Italy;Poland;Spain;Switzerland;United States
2019 Phase 2 NCT03971643 Canada;Poland;United States
Xilonix
Janssen Research & Development, LLC
2014 Phase 2 NCT01965613 United States