272. 進行性骨化性線維異形成症 Disease details / Clinical trials / Drug dev / DR info

Acido fusidico/idrocortisone acetato
   IPSEN PHARMA SAS
      -   Phase 3   EUCTR2021-002244-70-IT   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
Andecaliximab
   Ashibio Inc
      2024   Phase 2/Phase 3   NCT06508021   United States
AZD0530
   VU University Medical Center
      2020   Phase 2   EUCTR2019-003324-20-NL   Netherlands
AZD0530 difumarate
   Amsterdam UMC, location VUmc
      2020   Phase 2   NCT04307953   Germany;Netherlands;United Kingdom
Covid-19 vaccine moderna
   Amsterdam University Medical Center
      2023   Phase 2   EUCTR2022-000692-39-NL   Netherlands
Emea/H/C/005791
   Amsterdam University Medical Center
      2023   Phase 2   EUCTR2022-000692-39-NL   Netherlands
Fidrisertib
   Negar Karimian
      2023   Phase 2   JPRN-jRCT2041220080   Argentina;Australia;Belgium;Brazil;Canada;China;Columbia;France;Germany;Italy;Japan;Korea republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
Fidrisertib (IPN60130) 10 MG capsules
   Clementia Pharmaceuticals Inc, an Ipsen Company
      2023   Phase 2   EUCTR2020-002858-24-BE   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2022   Phase 2   EUCTR2020-002858-24-SE   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2022   Phase 2   EUCTR2020-002858-24-NL   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
Fidrisertib (IPN60130) 50 MG capsules
   Clementia Pharmaceuticals Inc, an Ipsen Company
      2023   Phase 2   EUCTR2020-002858-24-BE   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2022   Phase 2   EUCTR2020-002858-24-SE   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2022   Phase 2   EUCTR2020-002858-24-NL   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
Fidsertib
   Clementia Pharmaceuticals Inc, an Ipsen Company
      2022   Phase 2   EUCTR2020-002858-24-NL   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
Garetosmab
   Regeneron Pharmaceuticals
      2022   Phase 3   NCT05394116   Australia;Brazil;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Republic of;Malaysia;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
      2021   Phase 3   NCT04577820   -
   Regeneron Pharmaceuticals, Inc.
      2023   Phase 3   EUCTR2022-000880-40-NL   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Democratic People's Republic of;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2022-000880-40-FR   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Democratic People's Republic of;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2022-000880-40-FI   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Democratic People's Republic of;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
   Rhee Susan
      2023   Phase 3   JPRN-jRCT2041220096   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
Idrocortisone acetato dynacren - 1 % crema 1 tubo DA 30 G
   IPSEN PHARMA SAS
      -   Phase 3   EUCTR2021-002244-70-IT   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
Idrocortisone acetato dynacren 1% crema
   IPSEN PHARMA SAS
      -   Phase 3   EUCTR2021-002244-70-IT   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
INCB000928
   Incyte Corporation
      2022   Phase 2   NCT05090891   Argentina;Australia;Brazil;Canada;Chile;China;France;Germany;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;Russian Federation;South Africa;Spain;Turkey;United Kingdom;United States
      2022   Phase 2   EUCTR2021-002286-17-FR   Australia;Brazil;Canada;France;Germany;Korea, Republic of;Netherlands;Portugal;Russian Federation;United Kingdom;United States
      -   Phase 2   EUCTR2021-002286-17-DE   Australia;Brazil;Canada;Chile;China;France;Germany;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;South Africa;Spain;Switzerland;Türkiye;United Kingdom;United States
INCB000928 fumarate dihydrate
   Incyte Corporation
      2023   Phase 2   EUCTR2021-002286-17-PT   Australia;Brazil;Canada;Chile;China;France;Germany;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;South Africa;Spain;Switzerland;Turkey;United Kingdom;United States
      2023   Phase 2   EUCTR2021-002286-17-NL   Australia;Brazil;Canada;Chile;China;France;Germany;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;South Africa;Spain;Switzerland;Turkey;United Kingdom;United States
IPN60120
   IPSEN PHARMA SAS
      -   Phase 3   EUCTR2021-002244-70-IT   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
   Ipsen Pharma SAS
      2022   Phase 3   EUCTR2021-002244-70-FR   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
      -   Phase 3   EUCTR2021-002244-70-SE   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
IPN60130
   Clementia Pharmaceuticals Inc.
      2021   Phase 2   NCT05039515   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
IPN60130 10 MG capsules
   CLEMENTIA PHARMACEUTICALS INC.
      2021   Phase 2   EUCTR2020-002858-24-IT   Argentina;Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
   Clementia Pharmaceuticals Inc, an Ipsen Company
      2023   Phase 2   EUCTR2020-002858-24-PT   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2021   Phase 2   EUCTR2020-002858-24-FR   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;United Kingdom;United States
      2021   Phase 2   EUCTR2020-002858-24-ES   Argentina;Australia;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
      -   Phase 2   EUCTR2020-002858-24-DE   Argentina;Australia;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
IPN60130 50 MG capsules
   CLEMENTIA PHARMACEUTICALS INC.
      2021   Phase 2   EUCTR2020-002858-24-IT   Argentina;Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
   Clementia Pharmaceuticals Inc, an Ipsen Company
      2023   Phase 2   EUCTR2020-002858-24-PT   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2021   Phase 2   EUCTR2020-002858-24-FR   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;United Kingdom;United States
      2021   Phase 2   EUCTR2020-002858-24-ES   Argentina;Australia;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
      -   Phase 2   EUCTR2020-002858-24-DE   Argentina;Australia;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
Midazolam
   Clementia Pharmaceuticals Inc.
      2019   Phase 1   NCT04829773   United States
Palovarotene
   Clementia Pharmaceuticals Inc
      2018   Phase 3   EUCTR2017-002541-29-NL   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002541-29-SE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002541-29-GB   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Spain;Sweden;United Kingdom;United States
      2017   Phase 3   EUCTR2017-002541-29-ES   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
      -   Phase 3   EUCTR2017-002541-29-FR   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
   Clementia Pharmaceuticals Inc.
      2022   Phase 2   EUCTR2016-002526-36-FR   France
      2019   Phase 1   NCT04829773   United States
      2017   Phase 3   NCT03312634   Argentina;Australia;Brazil;Canada;France;Italy;Japan;Spain;Sweden;United Kingdom;United States
      2015   Phase 2   NCT02521792   France;United Kingdom;United States
      2015   Phase 2   EUCTR2014-002496-28-GB   Argentina;Australia;United Kingdom;United States
      2015   Phase 2   EUCTR2014-001453-17-GB   Argentina;United Kingdom;United States
      2014   Phase 2   NCT02190747   France;United Kingdom;United States
      -   Phase 3   EUCTR2017-002541-29-Outside-EU/EEA   Argentina;Australia;Brazil;Canada;Japan;United States
      -   Phase 2   EUCTR2014-002496-28-Outside-EU/EEA   Argentina;Australia;United States
   IPSEN PHARMA SAS
      -   Phase 3   EUCTR2021-002244-70-IT   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
   Ipsen
      2022   Phase 3   NCT05027802   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
   Ipsen Pharma SAS
      2022   Phase 3   EUCTR2021-002244-70-FR   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
      -   Phase 3   EUCTR2021-002244-70-SE   Argentina;Australia;Brazil;Canada;France;Italy;Spain;Sweden;United Kingdom;United States
Palovarotene - 1.5MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 10 MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 1MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 2 MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 2.5 MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 3 MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 4 MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene - 5 MG
   Clementia Pharmaceuticals Inc
      -   Phase 3   EUCTR2017-002541-29-DE   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene 1.5 MG
   CLEMENTIA PHARMACEUTICALS INC.
      2018   Phase 3   EUCTR2017-002541-29-IT   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene dose level 1
   Clementia Pharmaceuticals Inc.
      2014   Phase 2   NCT02279095   Argentina;Australia;France;United Kingdom;United States
Palovarotene dose level 2
   Clementia Pharmaceuticals Inc.
      2014   Phase 2   NCT02279095   Argentina;Australia;France;United Kingdom;United States
Palovarotene dose level 3
   Clementia Pharmaceuticals Inc.
      2014   Phase 2   NCT02279095   Argentina;Australia;France;United Kingdom;United States
Palovarotene dose level 4
   Clementia Pharmaceuticals Inc.
      2014   Phase 2   NCT02279095   Argentina;Australia;France;United Kingdom;United States
Palovarotene-2 MG
   CLEMENTIA PHARMACEUTICALS INC.
      2018   Phase 3   EUCTR2017-002541-29-IT   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene-3 MG
   CLEMENTIA PHARMACEUTICALS INC.
      2018   Phase 3   EUCTR2017-002541-29-IT   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Palovarotene-4 MG
   CLEMENTIA PHARMACEUTICALS INC.
      2018   Phase 3   EUCTR2017-002541-29-IT   Argentina;Australia;Brazil;Canada;France;Germany;Italy;Japan;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;Russian Federation;South Africa;Spain;Sweden;United Kingdom;United States
Perhexiline
   Nagoya University Graduate School of Medicine
      2010   Phase 1,2   JPRN-UMIN000019348   Japan
Piperazine
   CLEMENTIA PHARMACEUTICALS INC.
      2021   Phase 2   EUCTR2020-002858-24-IT   Argentina;Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
   Clementia Pharmaceuticals Inc, an Ipsen Company
      2023   Phase 2   EUCTR2020-002858-24-PT   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2023   Phase 2   EUCTR2020-002858-24-BE   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2022   Phase 2   EUCTR2020-002858-24-SE   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2022   Phase 2   EUCTR2020-002858-24-NL   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Spain;Sweden;United Kingdom;United States
      2021   Phase 2   EUCTR2020-002858-24-FR   Argentina;Australia;Belgium;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Portugal;Russian Federation;Spain;Sweden;United Kingdom;United States
      2021   Phase 2   EUCTR2020-002858-24-ES   Argentina;Australia;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
      -   Phase 2   EUCTR2020-002858-24-DE   Argentina;Australia;Brazil;Canada;China;Colombia;France;Germany;Italy;Japan;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;United States
REGN2477
   REGENERON PHARMACEUTICALS, INC.
      2017   Phase 2   EUCTR2016-005035-33-IT   Argentina;Brazil;France;Italy;Netherlands;Spain;United Kingdom;United States
   Regeneron Pharmaceuticals
      2018   Phase 2   NCT03188666   Canada;Colombia;France;Italy;Netherlands;Poland;Spain;United Kingdom;United States
   Regeneron Pharmaceuticals, Inc.
      2023   Phase 3   EUCTR2022-000880-40-NL   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Democratic People's Republic of;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2022-000880-40-FR   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Democratic People's Republic of;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
      2022   Phase 3   EUCTR2022-000880-40-FI   Australia;Brazil;Canada;Chile;China;Colombia;Finland;France;Hong Kong;Italy;Japan;Korea, Democratic People's Republic of;Malaysia;Mexico;Netherlands;Poland;South Africa;Spain;United Kingdom;United States
      2019   Phase 2   EUCTR2016-005035-33-ES   Canada;Colombia;France;Italy;Mexico;Netherlands;Poland;Spain;United Kingdom;United States
      2018   Phase 2   EUCTR2016-005035-33-NL   Argentina;Brazil;France;Italy;Netherlands;Spain;United Kingdom;United States
      2017   Phase 2   EUCTR2016-005035-33-GB   Canada;Colombia;France;Italy;Mexico;Netherlands;Poland;Spain;United Kingdom;United States
Saracatinib difumarate
   VU University Medical Center
      2020   Phase 2   EUCTR2019-003324-20-NL   Netherlands
Zilurgisertib
   Incyte Corporation
      2023   Phase 2   EUCTR2021-002286-17-NL   Australia;Brazil;Canada;Chile;China;France;Germany;Italy;Korea, Republic of;Mexico;Netherlands;New Zealand;Portugal;South Africa;Spain;Switzerland;Turkey;United Kingdom;United States