285. ファンコニ貧血 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 69 / 薬物数 : 109 - (DrugBank : 37) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 169
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
Abatacept
Emory University
2014 Phase 1 NCT01917708 United States
Afatinib
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
2024 Phase 1/Phase 2 NCT06648096 Germany;Spain
Alcohol
Masonic Cancer Center, University of Minnesota
2022 - NCT05973656 United States
Alefacept
Emory University
2010 - NCT01319851 United States
Alemtuzumab
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Allogeneic bone marrow transplantation
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
1998 Phase 1 NCT00317876 Brazil;United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Allogeneic hematopoietic stem cell transplantation
Fred Hutchinson Cancer Research Center
2000 Phase 1 NCT00093743 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
Amcell clinimacs
Children's Hospital Medical Center, Cincinnati
2007 Phase 1/Phase 2 NCT00479115 United States
AMD3100
Children's Hospital Medical Center, Cincinnati
2007 Phase 1/Phase 2 NCT00479115 United States
ANTI-CD45
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
ANTI-thymocyte globulin
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
AP1903
Bellicum Pharmaceuticals, Inc.
2017 Phase 1;Phase 2 EUCTR2016-003226-16-IT Italy
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
ATG
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States
Biopsy
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
2002 - NCT00896740 United States
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
Biospecimen collection
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Masonic Cancer Center, University of Minnesota
2022 - NCT05973656 United States
Bone marrow aspiration
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Bone marrow transplantation
Masonic Cancer Center, University of Minnesota
2006 Phase 2/Phase 3 NCT00352976 United States
BPX-501 cells
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
BPX-501 T cells
Bellicum Pharmaceuticals
2014 Phase 1/Phase 2 NCT02065869 Germany;Italy;Spain;United Kingdom;United States
Breath test
Masonic Cancer Center, University of Minnesota
2022 - NCT05973656 United States
Busulfan
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2002 Phase 2 NCT00258427 United States
1999 - NCT00290628 United States
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
2009 Phase 2 NCT00987480 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Campath 1H
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
CD34 selected haploidentical pbsct
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
CD34+ cell enriched stem cell graft
University of Florida
2025 - NCT06731036 -
CD34+ cells
FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO NIÑO JESUS
2013 - EUCTR2011-006100-12-ES Spain
CD34+ selected cells
Neena Kapoor, M.D.
2011 - NCT02127905 United States
CD34+cells
Rocket Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2018-002502-31-GB Spain;United Kingdom
2018 Phase 2 EUCTR2018-002502-31-ES Spain
Chemotherapy
Children's Hospital Medical Center, Cincinnati
2009 Phase 2 NCT01082133 United States
Clinimacs device
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States
Clinimacs prodigy system
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Computed tomography
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Cyclophosphamide
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
1998 Phase 1 NCT00317876 Brazil;United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2006 Phase 2/Phase 3 NCT00352976 United States
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
2009 Phase 2 NCT00987480 United States
2001 - NCT00595127 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Cyclophosphamide, fludarabine
Masonic Cancer Center, University of Minnesota
2004 Phase 1/Phase 2 NCT00167206 United States
Cyclosporine
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
1998 Phase 1 NCT00317876 Brazil;United States
Masonic Cancer Center, University of Minnesota
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States
Cytogenetic analysis
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
Danazol
Boston Children's Hospital
2009 Phase 1/Phase 2 NCT01001598 United States
Depleted stem cell transplant
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Donor mobilized pbsc infusion
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Eltrombopag
Julian Sevilla
2020 Phase 2 NCT06045052 Spain
National Heart, Lung, and Blood Institute (NHLBI)
2018 Phase 2 NCT03206086 United States
Enbrel*SC 4FL 25MG+4SIR 1ML
ISTITUTO GIANNINA GASLINI
2005 - EUCTR2004-004914-18-IT Italy
Etanercept
Children's Hospital Medical Center, Cincinnati
2005 Early Phase 1 NCT00965666 United States
ISTITUTO GIANNINA GASLINI
2005 - EUCTR2004-004914-18-IT Italy
Filgrastim
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Hospital Universitari Vall d'Hebron Research Institute
2013 Phase 2 NCT02931071 Spain
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Flow cytometry
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
Fludarabine
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2006 Phase 2/Phase 3 NCT00352976 United States
2000 Phase 1/Phase 2 NCT00630253 United States
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
2009 Phase 2 NCT00987480 United States
2001 - NCT00595127 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
University of California, San Francisco
2011 - NCT01316549 United States
Fludarabine phosphate
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Fluorescence IN situ hybridization
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
FP-045
Foresee Pharmaceuticals Co., Ltd.
2023 Phase 1/Phase 2 NCT04522375 Turkey;United States
G-CSF
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Assistance Publique - Hôpitaux de Paris
2017 Phase 1/Phase 2 NCT02678533 France
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
GENE-modified autologous stem cells
Shenzhen Geno-Immune Medical Institute
2017 - NCT03351868 China
Genetically engineered hematopoietic stem progenitor cells
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Genetically engineered hematopoietic stem/progenitor cells
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Graft-versus-tumor induction therapy
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Hematopoietic stem cell transplant
Masonic Cancer Center, University of Minnesota
2004 Phase 1/Phase 2 NCT00167206 United States
Hematopoietic stem cell transplantation
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
Horse ANTI-thymocyte globulin
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Human whole exome
Xiaofan Zhu
2013 - NCT01995305 China
Immunologic technique
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
JSP191
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Laboratory biomarker analysis
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Leukapheresis
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Magnetic resonance imaging
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Melphalan
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
1999 - NCT00290628 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
Metformin
Ain Shams University
2022 Phase 3 NCT06519786 Egypt
Metformin HCL
Boston Children's Hospital
2018 Phase 2 NCT03398824 United States
Methotrexate
Fred Hutchinson Cancer Research Center
1998 Phase 1 NCT00317876 Brazil;United States
Methylprednisolone
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Microarray analysis
OHSU Knight Cancer Institute
2002 - NCT00896740 United States
Miltenyi clinimacs
Children's Hospital Medical Center, Cincinnati
2009 Phase 2 NCT01082133 United States
Mozobil
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Mycophenolate mofetil
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
Masonic Cancer Center, University of Minnesota
2006 Phase 2/Phase 3 NCT00352976 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Neupogen
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Nonmyeloablative allogeneic hematopoietic stem cell transplantation
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
1998 Phase 1 NCT00317876 Brazil;United States
Olaparib
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Baptist Health South Florida
2020 Phase 2 NCT04483544 United States
Oxandrolone
Children's Hospital Medical Center, Cincinnati
2004 Phase 1 NCT00243399 United States
Pembrolizumab
Baptist Health South Florida
2020 Phase 2 NCT04483544 United States
Peripheral blood stem cell
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Peripheral blood stem cell transplantation
Fred Hutchinson Cancer Research Center
2000 Phase 1 NCT00093743 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Plerixafor
Assistance Publique - Hôpitaux de Paris
2017 Phase 1/Phase 2 NCT02678533 France
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Hospital Universitari Vall d'Hebron Research Institute
2013 Phase 2 NCT02931071 Spain
PLérixafor
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Polymerase chain reaction
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
Prednisone
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Quercetin
Children's Hospital Medical Center, Cincinnati
2018 Phase 2 NCT03476330 United States
2012 Phase 1 NCT01720147 United States
Rabbit
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Rabbit ANTI-thymocyte globulin
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Rabbit ATG
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Radiation therapy
Masonic Cancer Center, University of Minnesota
1999 - NCT00290628 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Ratg
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Retrovirus construct
Boston Children’s Hospital
2004 Phase 1 NCT00272857 United States
Rimiducid
Bellicum Pharmaceuticals
2017 Phase 1/Phase 2 NCT03733249 Italy;Saudi Arabia;United Kingdom
2014 Phase 1/Phase 2 NCT02065869 Germany;Italy;Spain;United Kingdom;United States
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
Rituximab
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Rivogenlecleucel
Bellicum Pharmaceuticals
2017 Phase 1/Phase 2 NCT03733249 Italy;Saudi Arabia;United Kingdom
Bellicum Pharmaceuticals, Inc.
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
Rivogenleucleucel
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
RP-L102
Rocket Pharmaceuticals Inc.
2020 Phase 2 NCT04248439 United States
2019 Phase 2 NCT04069533 Spain;United Kingdom
2019 Phase 1 NCT03814408 United States
Rocket Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2018-002502-31-GB Spain;United Kingdom
2018 Phase 2 EUCTR2018-002502-31-ES Spain
Sargramostim
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Sirolimus
Masonic Cancer Center, University of Minnesota
2006 Phase 2/Phase 3 NCT00352976 United States
T cell infusion
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
Tacrolimus
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
TBI
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Memorial Sloan Kettering Cancer Center
2001 - NCT00595127 United States
THE clinimacs device
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
Therapeutic allogeneic lymphocytes
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Thiotepa
University of California, San Francisco
2017 - NCT03609840 United States
Thymic shielding during radiation
Masonic Cancer Center, University of Minnesota
2004 Phase 1/Phase 2 NCT00167206 United States
Thymoglobulin
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Total body irradiation
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2006 Phase 2/Phase 3 NCT00352976 United States
2004 Phase 1/Phase 2 NCT00167206 United States
Memorial Sloan Kettering Cancer Center
2001 - NCT00595127 United States
Total-body irradiation
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
Transduced CD34+ cells
National Heart, Lung, and Blood Institute (NHLBI)
1993 Phase 1 NCT00001399 United States
Umbilical cord blood transplantation
Masonic Cancer Center, University of Minnesota
1999 - NCT00290628 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Whole genomic
Xiaofan Zhu
2013 - NCT01995305 China
Zarzio
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Emory University
2014 Phase 1 NCT01917708 United States
Afatinib
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
2024 Phase 1/Phase 2 NCT06648096 Germany;Spain
Alcohol
Masonic Cancer Center, University of Minnesota
2022 - NCT05973656 United States
Alefacept
Emory University
2010 - NCT01319851 United States
Alemtuzumab
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Allogeneic bone marrow transplantation
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
1998 Phase 1 NCT00317876 Brazil;United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Allogeneic hematopoietic stem cell transplantation
Fred Hutchinson Cancer Research Center
2000 Phase 1 NCT00093743 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
Amcell clinimacs
Children's Hospital Medical Center, Cincinnati
2007 Phase 1/Phase 2 NCT00479115 United States
AMD3100
Children's Hospital Medical Center, Cincinnati
2007 Phase 1/Phase 2 NCT00479115 United States
ANTI-CD45
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
ANTI-thymocyte globulin
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
AP1903
Bellicum Pharmaceuticals, Inc.
2017 Phase 1;Phase 2 EUCTR2016-003226-16-IT Italy
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
ATG
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States
Biopsy
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
2002 - NCT00896740 United States
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
Biospecimen collection
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Masonic Cancer Center, University of Minnesota
2022 - NCT05973656 United States
Bone marrow aspiration
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Bone marrow transplantation
Masonic Cancer Center, University of Minnesota
2006 Phase 2/Phase 3 NCT00352976 United States
BPX-501 cells
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
BPX-501 T cells
Bellicum Pharmaceuticals
2014 Phase 1/Phase 2 NCT02065869 Germany;Italy;Spain;United Kingdom;United States
Breath test
Masonic Cancer Center, University of Minnesota
2022 - NCT05973656 United States
Busulfan
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2002 Phase 2 NCT00258427 United States
1999 - NCT00290628 United States
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
2009 Phase 2 NCT00987480 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Campath 1H
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
CD34 selected haploidentical pbsct
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
CD34+ cell enriched stem cell graft
University of Florida
2025 - NCT06731036 -
CD34+ cells
FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO NIÑO JESUS
2013 - EUCTR2011-006100-12-ES Spain
CD34+ selected cells
Neena Kapoor, M.D.
2011 - NCT02127905 United States
CD34+cells
Rocket Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2018-002502-31-GB Spain;United Kingdom
2018 Phase 2 EUCTR2018-002502-31-ES Spain
Chemotherapy
Children's Hospital Medical Center, Cincinnati
2009 Phase 2 NCT01082133 United States
Clinimacs device
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States
Clinimacs prodigy system
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Computed tomography
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Cyclophosphamide
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
1998 Phase 1 NCT00317876 Brazil;United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2006 Phase 2/Phase 3 NCT00352976 United States
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
2009 Phase 2 NCT00987480 United States
2001 - NCT00595127 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Cyclophosphamide, fludarabine
Masonic Cancer Center, University of Minnesota
2004 Phase 1/Phase 2 NCT00167206 United States
Cyclosporine
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
1998 Phase 1 NCT00317876 Brazil;United States
Masonic Cancer Center, University of Minnesota
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States
Cytogenetic analysis
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
Danazol
Boston Children's Hospital
2009 Phase 1/Phase 2 NCT01001598 United States
Depleted stem cell transplant
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Donor mobilized pbsc infusion
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Eltrombopag
Julian Sevilla
2020 Phase 2 NCT06045052 Spain
National Heart, Lung, and Blood Institute (NHLBI)
2018 Phase 2 NCT03206086 United States
Enbrel*SC 4FL 25MG+4SIR 1ML
ISTITUTO GIANNINA GASLINI
2005 - EUCTR2004-004914-18-IT Italy
Etanercept
Children's Hospital Medical Center, Cincinnati
2005 Early Phase 1 NCT00965666 United States
ISTITUTO GIANNINA GASLINI
2005 - EUCTR2004-004914-18-IT Italy
Filgrastim
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Hospital Universitari Vall d'Hebron Research Institute
2013 Phase 2 NCT02931071 Spain
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Flow cytometry
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
Fludarabine
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2006 Phase 2/Phase 3 NCT00352976 United States
2000 Phase 1/Phase 2 NCT00630253 United States
Medical College of Wisconsin
2009 Phase 2 NCT01071239 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
2009 Phase 2 NCT00987480 United States
2001 - NCT00595127 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
University of California, San Francisco
2011 - NCT01316549 United States
Fludarabine phosphate
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Fluorescence IN situ hybridization
OHSU Knight Cancer Institute
2002 - NCT00899795 United States
FP-045
Foresee Pharmaceuticals Co., Ltd.
2023 Phase 1/Phase 2 NCT04522375 Turkey;United States
G-CSF
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Assistance Publique - Hôpitaux de Paris
2017 Phase 1/Phase 2 NCT02678533 France
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
GENE-modified autologous stem cells
Shenzhen Geno-Immune Medical Institute
2017 - NCT03351868 China
Genetically engineered hematopoietic stem progenitor cells
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Genetically engineered hematopoietic stem/progenitor cells
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Graft-versus-tumor induction therapy
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Hematopoietic stem cell transplant
Masonic Cancer Center, University of Minnesota
2004 Phase 1/Phase 2 NCT00167206 United States
Hematopoietic stem cell transplantation
Masonic Cancer Center, University of Minnesota
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
Horse ANTI-thymocyte globulin
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Human whole exome
Xiaofan Zhu
2013 - NCT01995305 China
Immunologic technique
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
JSP191
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Laboratory biomarker analysis
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Leukapheresis
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Magnetic resonance imaging
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Melphalan
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
1999 - NCT00290628 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
Metformin
Ain Shams University
2022 Phase 3 NCT06519786 Egypt
Metformin HCL
Boston Children's Hospital
2018 Phase 2 NCT03398824 United States
Methotrexate
Fred Hutchinson Cancer Research Center
1998 Phase 1 NCT00317876 Brazil;United States
Methylprednisolone
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2002 Phase 2 NCT00258427 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Microarray analysis
OHSU Knight Cancer Institute
2002 - NCT00896740 United States
Miltenyi clinimacs
Children's Hospital Medical Center, Cincinnati
2009 Phase 2 NCT01082133 United States
Mozobil
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Mycophenolate mofetil
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
Masonic Cancer Center, University of Minnesota
2006 Phase 2/Phase 3 NCT00352976 United States
2000 Phase 1/Phase 2 NCT00630253 United States
1999 - NCT00290628 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Neupogen
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Nonmyeloablative allogeneic hematopoietic stem cell transplantation
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
1998 Phase 1 NCT00317876 Brazil;United States
Olaparib
Academic and Community Cancer Research United
2020 Phase 2 NCT04042831 United States
Baptist Health South Florida
2020 Phase 2 NCT04483544 United States
Oxandrolone
Children's Hospital Medical Center, Cincinnati
2004 Phase 1 NCT00243399 United States
Pembrolizumab
Baptist Health South Florida
2020 Phase 2 NCT04483544 United States
Peripheral blood stem cell
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Peripheral blood stem cell transplantation
Fred Hutchinson Cancer Research Center
2000 Phase 1 NCT00093743 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Plerixafor
Assistance Publique - Hôpitaux de Paris
2017 Phase 1/Phase 2 NCT02678533 France
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Great Ormond Street Hospital NHS foundation Trust
2015 Phase 2 EUCTR2014-004272-29-GB France;Spain;United Kingdom
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
2016 Phase 1/Phase 2 NCT03157804 Spain
Hospital Universitari Vall d'Hebron Research Institute
2013 Phase 2 NCT02931071 Spain
PLérixafor
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France
Polymerase chain reaction
University Hospital Freiburg
2007 - NCT00499070 Austria;Belgium;Czech Republic;Denmark;Germany;Ireland;Italy;Netherlands;Poland;Spain;Switzerland
Prednisone
Fred Hutchinson Cancer Center
2012 Phase 1 NCT01331018 United States
Quercetin
Children's Hospital Medical Center, Cincinnati
2018 Phase 2 NCT03476330 United States
2012 Phase 1 NCT01720147 United States
Rabbit
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Rabbit ANTI-thymocyte globulin
Columbia University
2002 Phase 2/Phase 3 NCT01019876 United States
Rabbit ATG
Children's Hospital Medical Center, Cincinnati
2014 Phase 2 NCT02143830 United States
Radiation therapy
Masonic Cancer Center, University of Minnesota
1999 - NCT00290628 United States
Milton S. Hershey Medical Center
2003 Phase 2 NCT00084695 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Ratg
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Retrovirus construct
Boston Children’s Hospital
2004 Phase 1 NCT00272857 United States
Rimiducid
Bellicum Pharmaceuticals
2017 Phase 1/Phase 2 NCT03733249 Italy;Saudi Arabia;United Kingdom
2014 Phase 1/Phase 2 NCT02065869 Germany;Italy;Spain;United Kingdom;United States
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
Rituximab
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Rivogenlecleucel
Bellicum Pharmaceuticals
2017 Phase 1/Phase 2 NCT03733249 Italy;Saudi Arabia;United Kingdom
Bellicum Pharmaceuticals, Inc.
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom
Rivogenleucleucel
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom
RP-L102
Rocket Pharmaceuticals Inc.
2020 Phase 2 NCT04248439 United States
2019 Phase 2 NCT04069533 Spain;United Kingdom
2019 Phase 1 NCT03814408 United States
Rocket Pharmaceuticals, Inc.
2020 Phase 2 EUCTR2018-002502-31-GB Spain;United Kingdom
2018 Phase 2 EUCTR2018-002502-31-ES Spain
Sargramostim
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Sirolimus
Masonic Cancer Center, University of Minnesota
2006 Phase 2/Phase 3 NCT00352976 United States
T cell infusion
Baylor College of Medicine
2002 Phase 1 NCT00586274 United States
Tacrolimus
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
TBI
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
Memorial Sloan Kettering Cancer Center
2001 - NCT00595127 United States
THE clinimacs device
Memorial Sloan Kettering Cancer Center
2018 Phase 2 NCT03600909 United States
Therapeutic allogeneic lymphocytes
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
Thiotepa
University of California, San Francisco
2017 - NCT03609840 United States
Thymic shielding during radiation
Masonic Cancer Center, University of Minnesota
2004 Phase 1/Phase 2 NCT00167206 United States
Thymoglobulin
Porteus, Matthew, MD
2021 Phase 1/Phase 2 NCT04784052 United States
Total body irradiation
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States
2006 Phase 2/Phase 3 NCT00352976 United States
2004 Phase 1/Phase 2 NCT00167206 United States
Memorial Sloan Kettering Cancer Center
2001 - NCT00595127 United States
Total-body irradiation
Fred Hutchinson Cancer Research Center
2007 Phase 2 NCT00453388 Brazil;United States
2000 Phase 1 NCT00093743 United States
Roswell Park Cancer Institute
2009 - NCT00856388 United States
Transduced CD34+ cells
National Heart, Lung, and Blood Institute (NHLBI)
1993 Phase 1 NCT00001399 United States
Umbilical cord blood transplantation
Masonic Cancer Center, University of Minnesota
1999 - NCT00290628 United States
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States
University of California, San Francisco
2000 Phase 1/Phase 2 NCT00305708 United States
Whole genomic
Xiaofan Zhu
2013 - NCT01995305 China
Zarzio
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2014-005264-14-FR France