70. 広範脊柱管狭窄症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 127 / 薬物数 : 178 - (DrugBank : 67) / 標的遺伝子数 : 87 - 標的パスウェイ数 : 99
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
0.5% marcaine
University of Southern California
2016 - NCT02932020 United States
0.9% saline
Vanderbilt University Medical Center
2009 Phase 4 NCT00808665 United States
0.9% sodium chloride injection
Poznan University of Medical Sciences
2024 Phase 4 NCT06233617 Poland
0002-8971
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
124I-evuzamitide
University of Tennessee Graduate School of Medicine
2025 Phase 2 NCT06907849 United States
1MG/KG/HR TXA intravenous infusion till THE last suture
Peking Union Medical College Hospital
2017 - NCT03011866 -
Acetaminophen
Hospital for Special Surgery, New York
2016 - NCT02700451 United States
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Acetate
Qilu Hospital of Shandong University
2018 - ChiCTR1800016968 China
Activematrix
Baylor College of Medicine
2022 Phase 4 NCT05297513 -
Acupuncture
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Shaozhou People's Hospital
2022 - ChiCTR2200063478 China
Taipei Medical University Hospital
2019 - NCT03801512 Taiwan
Adjunctive analgesics
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Adjunctive ANTI-depressants
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
AK1320 MS
Asahi Kasei Pharma Corporation
2020 Phase 1 NCT04483297 Canada
Alanine
University of California, Irvine
2025 - NCT06579391 United States
Allogen-LI
University of Southern California
2016 - NCT02932020 United States
Allograft
Mesoblast, Ltd.
2010 Phase 2 NCT01097486 United States
Alprostadil
Tokai University Hospital Department of Orthopaedic Surgery
2010 - JPRN-UMIN000005959 Japan
Amino acids
Wakayama Medical University
2018 - JPRN-UMIN000030881 Japan
Aminocaproic acid
National Heart, Lung, and Blood Institute (NHLBI)
2000 - NCT00320619 United States
Amniotic fluid allograft
University of Utah
2021 Phase 1/Phase 2 NCT04537026 United States
Apple watch and APP
Stanford University
2020 - NCT04379921 United States
Baclofen (baclofen TAB. 10MG) treatment
Yonsei University
2022 - NCT05392361 Korea, Republic of
BEE venom pharmacopuncture
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Bilateral transforaminal epidural steroid injections
Marshfield Clinic Research Foundation
2013 - NCT01995461 United States
Bioactive glass-ceramic spacer
BioAlpha Inc.
2010 - NCT03532945 -
Bone marrow concentrate
Stem Cures
2018 Phase 2/Phase 3 NCT04559295 United States
Botulinum toxin type A (nabota®) injection into THE gastrocnemius muscle
Yonsei University
2015 - NCT02444351 Korea, Republic of
Bupivacaine
2020 Phase 4 EUCTR2019-003590-25-NL Netherlands
Bupivacaine-epinephrine 0.25%-1:200,000 injectable solution plus clonidine
John O'Toole
2022 Phase 4 NCT05029726 United States
BupivacaïNE HCL 0,125% / sufentanil 50 µG flacon à 50 ML
2020 Phase 4 EUCTR2019-003590-25-NL Netherlands
Buprenorphine
Seoul National University Hospital
2015 Phase 4 NCT02416804 Korea, Republic of
Caudal epidural injection with celestone
Pain Management Center of Paducah
2007 Phase 0 NCT00370799 United States
Caudal epidural injection with depomedrol
Pain Management Center of Paducah
2007 Phase 0 NCT00370799 United States
Caudal epidural injection with generic celestone
Pain Management Center of Paducah
2007 Phase 0 NCT00370799 United States
Celebrex 200MG capsule
Seoul National University Bundang Hospital
2018 Phase 4 NCT03584074 -
Celecoxib
Department of Orthopedic Surgery Kobe University Graduate School of Medicine
2012 - JPRN-UMIN000007419 Japan
The First Affiliated Hospital of Chongqing Medical University
2020 Phase 0 ChiCTR2000028775 China
The Third Affiliated Hospital of Southern Medical University
2024 Phase 4 ChiCTR2400092866 China
University of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
2011 Phase 3 JPRN-UMIN000004825 Japan
Wang Jing Hospital, Chinese Academy of Traditional Chinese Medicine
2021 - ChiCTR2100046515 China
Centerpiece titanium plate
Xijing Hospital
2023 - NCT05786313 China
Cervical interbody fusion
Induce Biologics USA Inc.
2024 - NCT06000319 United States
Chuna manipulation
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2017 - NCT02975011 Korea, Republic of
Chuna manual medicine
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
Cilostazol
Juntendo University Department of Orthopaedic Surgery
2011 - JPRN-UMIN000006588 Japan
Creatinine
Nikaido Takuya
2020 - JPRN-jRCTs021200007 -
Cupping
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Darvocet
University of Rochester
2008 Phase 4 NCT00652093 United States
Decadron phosphate, injectable
Hospital for Special Surgery, New York
2017 Phase 4 NCT03245671 United States
Definity perflutren lipid microsphere ultrasound contrast
Medical University of South Carolina
2023 - NCT05530798 United States
Deksmedetomidiini
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Demineralized bone matrix
OhioHealth
2014 - NCT02070484 United States
Denosumab
The First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology
2021 Phase 4 ChiCTR2100053054 China
DEPO-medrol 40MG/ML suspension FOR injection
Hospital for Special Surgery, New York
2021 Phase 3 NCT05058287 United States
Depomedrol
Europainclinics z.ú.
2021 - NCT02459392 Czech Republic;Czechia
University of Southern California
2016 - NCT02932020 United States
Dexamethasone
Potsawat Surabotsopon
2024 Phase 4 NCT06367855 -
Dexamethasone 4 MG/ML injectable solution
Poznan University of Medical Sciences
2024 Phase 4 NCT06233617 Poland
Dexamethasone sodium phosphate
University of Utah
2021 Phase 1/Phase 2 NCT04537026 United States
Dexdor
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Dexmedetomidine
Vanderbilt University Medical Center
2009 Phase 4 NCT00808665 United States
Dexmedetomidine group
New York University School of Medicine
2010 - NCT01377623 United States
Yonsei University
2016 - NCT02902380 Korea, Republic of
Dexmedetomidine hydrochloride
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Dexmedetomidine injection
Poznan University of Medical Sciences
2024 Phase 4 NCT06233617 Poland
Dexmedetomidine with ropivacaine
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Diphenhydramine
University of Rochester
2008 Phase 4 NCT00638443 United States
Eaca
National Heart, Lung, and Blood Institute (NHLBI)
2000 - NCT00320619 United States
Elcatonin
Zhejiang province hospital of Chinese medicine
2024 Phase 0 ChiCTR2400083358 China
Electroacupuncture
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Epidural injection
Tel-Aviv Sourasky Medical Center
2016 Phase 2/Phase 3 NCT02725723 -
Epidural local anesthetic injection
University of Washington
2011 Phase 4 NCT01238536 United States
Epidural steroid (dexamethasone) injection
Keimyung University Dongsan Medical Center
2016 - NCT02838615 -
Epidural steroid injection
Coastal Orthopedics & Sports Medicine
2009 Phase 4 NCT00995371 United States
Hadassah Medical Organization
2013 Phase 4 NCT01934868 Israel
Hospital for Special Surgery, New York
2017 Phase 4 NCT03245671 United States
University of Washington
2011 Phase 4 NCT01238536 United States
Vertos Medical, Inc.
2014 - NCT02093520 United States
2011 - NCT01315145 United States
Epidural steroid with local anesthetic injection
University of Washington
2011 Phase 4 NCT01238536 United States
Epiduroscopy
Europainclinics z.ú.
2021 - NCT02459392 Czech Republic;Czechia
Erythropoietin
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
2017 - ChiCTR-INR-17012403 China
Esketamine hydrochloride
Helsinki Universiy Central Hospital
2012 Phase 4 EUCTR2012-000747-26-FI Finland
Essential amino acids
University of California, Irvine
2025 - NCT06579391 United States
Etoricoxib
Zhejiang province hospital of Chinese medicine
2024 Phase 0 ChiCTR2400083358 China
Fentanyl
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Forsteo
Department of Orthopaedics IKE
2011 Phase 4 EUCTR2011-002917-12-SE Sweden
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Forteo
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Gabapentin
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Gabapentin (neurontin® capsule 300MG) treatment
Yonsei University
2022 - NCT05392361 Korea, Republic of
Gelatin
Weifang People's Hospital
2023 - ChiCTR2300077538 China
2023 - ChiCTR2300076789 China
Goldic serum
Sutherland Medical Center
2020 Phase 4 NCT04492774 Poland
Group exercise: community setting
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Heparin
Seoul National University Bundang Hospital
2012 - NCT01522846 Korea, Republic of
Herbal medicine
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Hyaluronic acid
Europainclinics z.ú.
2021 - NCT02459392 Czech Republic;Czechia
Hydromorphone
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
I-factor
Sygehus Lillebaelt
2012 Phase 3 NCT01618435 Denmark
Individualized exercises: clinical setting
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Interleukin-6
Dept. of Orthopaedic Surgery, Graduate School of Medicine, Chiba University
2014 - JPRN-UMIN000015670 Japan
Kenalog injectable product
Hospital for Special Surgery, New York
2017 Phase 4 NCT03245671 United States
Ketamine
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
University of California, San Francisco
2023 Phase 3 NCT06140927 United States
University of Turku
2016 Phase 1;Phase 4 EUCTR2016-002887-14-FI Finland
Ketanest-S
Helsinki Universiy Central Hospital
2012 Phase 4 EUCTR2012-000747-26-FI Finland
University of Turku
2016 Phase 1;Phase 4 EUCTR2016-002887-14-FI Finland
Ketorolac
Hospital for Special Surgery, New York
2016 - NCT02700451 United States
Lidocaine hydrochloride, injectable
Stanford University
2021 Early Phase 1 NCT04992572 United States
Limaprost
Kansai LSS Forum
2014 - JPRN-UMIN000012918 Japan
Peking University Third Hospital
2023 Phase 4 ChiCTR2300076153 china
The Third Affiliated Hospital of Southern Medical University
2024 Phase 4 ChiCTR2400092866 China
University of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
2011 Phase 3 JPRN-UMIN000004825 Japan
Yungjin Pharm. Co., Ltd.
2013 Phase 4 NCT01888536 Korea, Republic of
Liposomal bupivacaine
Allina Health System
2019 Phase 4 NCT03745040 United States
University of Colorado, Denver
2019 Phase 2 NCT04066296 United States
Lobster device
Diametros Medical srl
2022 - NCT05587465 Italy
Lumbar epidural injection
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Lumbar interbody fusion
Induce Biologics USA Inc.
2024 - NCT06000319 United States
Lumbar interbody fusion with autograft
Mesoblast, Ltd.
2009 Phase 2 NCT00996073 United States
Lumbar interbody fusion with neofuse
Mesoblast, Ltd.
2009 Phase 2 NCT00996073 United States
Lumbar interlaminar epidural steroid injection
Emory University
2014 - NCT02103543 United States
Magnesium with ropivacaine
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Manual therapy
Sutherland Medical Center
2020 Phase 4 NCT04492774 Poland
Mastergraft granules
Mesoblast, Ltd.
2010 Phase 1/Phase 2 NCT01106417 Australia
Mecobalamin
Peking University Shougang Hospital
2023 Phase 4 ChiCTR2300073153 China
Wang Jing Hospital, Chinese Academy of Traditional Chinese Medicine
2021 - ChiCTR2100046515 China
Zhejiang province hospital of Chinese medicine
2024 Phase 0 ChiCTR2400083358 China
Metaxalone 640 MG oral tablet
Primus Pharmaceuticals
2023 Phase 4 NCT06157177 United States
Mild procedure
Vertos Medical, Inc.
2014 - NCT02093520 United States
Mirogabalin
Nikaido Takuya
2020 - JPRN-jRCTs021200007 -
Misoprostol
Dallas VA Medical Center
2019 - NCT04611464 United States
Modified-thoracolumbar interfascial plane block
Medipol University
2020 - NCT04189341 Turkey
Morphine PCA
University Hospital, Basel, Switzerland
2011 Phase 2/Phase 3 NCT01275547 Switzerland
Natural matrix protein (NMP) fibers
Induce Biologics USA Inc.
2024 - NCT06000319 United States
Neofuse
Mesoblast, Ltd.
2010 Phase 1/Phase 2 NCT01106417 Australia
2010 Phase 2 NCT01097486 United States
2007 Phase 1/Phase 2 NCT00549913 United States
Nicardipine
Yonsei University
2012 Phase 4 NCT02271191 -
Normal saline
John O'Toole
2022 Phase 4 NCT05029726 United States
Potsawat Surabotsopon
2024 Phase 4 NCT06367855 -
Seoul National University Hospital
2019 Phase 4 NCT04401735 Korea, Republic of
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
2017 - ChiCTR-INR-17012403 China
Xuanwu Hospital Capital Medical University
2023 - ChiCTR2500095855 China
Nsaids
Higashi Ohmiya general hospital
2010 - JPRN-UMIN000005382 Japan
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Nikaido Takuya
2020 - JPRN-jRCTs021200007 -
Nucel
OhioHealth
2014 - NCT02070484 United States
Oksikodoni
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Opana
University of Rochester
2008 Phase 4 NCT00652093 United States
Oxanest
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Oxycodone hydrochloride
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Oxycodone orion
University of Turku
2016 Phase 1;Phase 4 EUCTR2016-002887-14-FI Finland
Oxygen
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Yonsei University
2016 - NCT02625194 Korea, Republic of
Oxytocin nasal spray
Zhejiang University
2025 Phase 2 NCT06945926 China
Ozone
Shaozhou People's Hospital
2022 - ChiCTR2200063478 China
Parathyroid hormone
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Percutaneous lumbar decompression
Vertos Medical, Inc.
2011 - NCT01315145 United States
Phosphate
Histograft Co., Ltd.
2023 - NCT06365307 Russian Federation
Physical therapy
Emory University
2014 - NCT02103543 United States
Platelet rich plasma
Taipei Medical University Hospital
2019 - NCT03801512 Taiwan
PLF with autograft
Mesoblast, Ltd.
2008 Phase 1/Phase 2 NCT00810212 United States
PLF with neofuse
Mesoblast, Ltd.
2008 Phase 1/Phase 2 NCT00810212 United States
Polydeoxyribonucleotides
Seoul National University Hospital
2019 Phase 4 NCT04401735 Korea, Republic of
Posterolateral spinal fusion with instrumentation
Mesoblast, Ltd.
2007 Phase 1/Phase 2 NCT00549913 United States
Predinose oral
Federal University of São Paulo
2011 - NCT01456377 Brazil
Pregabalin
Department of Orthopedic Surgery Kobe University Graduate School of Medicine
2012 - JPRN-UMIN000007419 Japan
Northwestern University
2009 Phase 4 NCT00908375 United States
The First Affiliated Hospital of Chongqing Medical University
2020 Phase 0 ChiCTR2000028775 China
University of Rochester
2008 Phase 4 NCT00638443 United States
Yungjin Pharm. Co., Ltd.
2013 Phase 4 NCT01888536 Korea, Republic of
Pregabalin 75MG
Seoul National University Bundang Hospital
2018 Phase 4 NCT03584074 -
Prolotherapy solution OF 20% dextrose
Hadassah Medical Organization
2013 Phase 4 NCT01934868 Israel
Propofol
Beijing Municipal Geriatric Medical Research Center
2022 Phase 0 ChiCTR2200058808 China
Propofol injection
Stanford University
2021 Early Phase 1 NCT04992572 United States
Remifentanil
Peking University Third Hospital
2012 - ChiCTR-TRC-13003639 China
Yonsei University
2010 Phase 4 NCT01052324 Korea, Republic of
Rhpth
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Rocuronium bromide
Zheng Guo
2022 Early Phase 1 NCT05619848 China
Ropivacaine
Beijing Beijing Coal Group General Hospital
2023 - ChiCTR2300076493 China
Binzhou Medical University Hospital
2022 - ChiCTR2200061908 China
Higashi Ohmiya general hospital
2010 - JPRN-UMIN000005382 Japan
Second Hospital of Lanzhou University
2023 Phase 0 ChiCTR2300070414 China
Ropivacaine hydrochloride injection
Ilse van de Wijgert
2022 Phase 4 NCT05345249 Netherlands
Ropivacaine plus normal saline
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Ropivacaine, epinephrine, clonidine, and ketorolac injection cocktail
University of Maryland, Baltimore
2025 Phase 1/Phase 2 NCT06447194 United States
S-ketamine & midazolam
University Hospital, Basel, Switzerland
2011 Phase 2/Phase 3 NCT01275547 Switzerland
Selective nerve root block
The Cleveland Clinic
2018 Phase 4 NCT03801356 United States
Selexipag
Nippon Shinyaku Co., Ltd.
2018 Phase 2 JPRN-jRCT2080223810 Japan
Sevoflurane
Saglik Bilimleri Universitesi
2023 - NCT06558695 Turkey
Sodium chloride
Ilse van de Wijgert
2022 Phase 4 NCT05345249 Netherlands
Steroid
Taipei Medical University Hospital
2019 - NCT03801512 Taiwan
Steroid injections
Sutherland Medical Center
2020 Phase 4 NCT04492774 Poland
Sufentanil
Beijing Beijing Coal Group General Hospital
2023 - ChiCTR2300076493 China
Sugar pill
Northwestern University
2009 Phase 4 NCT00908375 United States
Surgical espb
Bursa City Hospital
2022 - NCT05630404 Turkey
Synthetic osteoplastic material based ON ß-TCP or bone autograft
Histograft Co., Ltd.
2023 - NCT06365307 Russian Federation
Teicoplanin
Bezmialem Vakif University
2020 Phase 3 NCT04341831 -
Teriparatide
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Qilu Hospital of Shandong University
2018 - ChiCTR1800016968 China
University Hospital, Linkoeping
2012 Phase 4 NCT02090244 Sweden
Therm-apptm TH, thermographic camera
Tel-Aviv Sourasky Medical Center
2016 Phase 2/Phase 3 NCT02725723 -
Titanium
Farhan Karim
2021 - NCT05023733 United States
Titanium cage
BioAlpha Inc.
2010 - NCT03532945 -
Tiva
Saglik Bilimleri Universitesi
2023 - NCT06558695 Turkey
Tramadol
Seoul National University Hospital
2015 Phase 4 NCT02416804 Korea, Republic of
Tramadol with ropivacaine
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Tranexamic acid
Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region
2022 Phase 4 ChiCTR2200063132 China
Massachusetts General Hospital
2012 Phase 4 NCT02063035 United States
Tranexamic acid 100 MG/ML
Hospital for Special Surgery, New York
2018 Phase 3 NCT03553186 United States
Transdermal fentanyl matrix, gabapentin
Seoul National University Hospital
2010 Phase 4 NCT01127100 Korea, Republic of
Transforaminal epidural injection
Eduard Verheijen
2020 - NCT04540068 Netherlands
Triamcinolone acetonide and normal saline solution
Navamindradhiraj University
2016 - NCT02939482 Thailand
Tylenol
Peking University Third Hospital
2019 - NCT04042948 China
Ulinastatin
Xuanwu Hospital Capital Medical University
2023 - ChiCTR2500095855 China
US guided espb
Bursa City Hospital
2022 - NCT05630404 Turkey
Vancomycin
Department of Spinal Surgery, Shenzhen Second People's Hospital
2023 Phase 0 ChiCTR2300073231 China
Taipei Veterans General Hospital, Taiwan
2018 - NCT03883022 Taiwan
Vivigen cellular bone matrix
Ohio State University
2019 Phase 4 NCT04007094 United States
Wound topically irrigated with 500MG TXA
Peking Union Medical College Hospital
2017 - NCT03011866 -
University of Southern California
2016 - NCT02932020 United States
0.9% saline
Vanderbilt University Medical Center
2009 Phase 4 NCT00808665 United States
0.9% sodium chloride injection
Poznan University of Medical Sciences
2024 Phase 4 NCT06233617 Poland
0002-8971
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
124I-evuzamitide
University of Tennessee Graduate School of Medicine
2025 Phase 2 NCT06907849 United States
1MG/KG/HR TXA intravenous infusion till THE last suture
Peking Union Medical College Hospital
2017 - NCT03011866 -
Acetaminophen
Hospital for Special Surgery, New York
2016 - NCT02700451 United States
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Acetate
Qilu Hospital of Shandong University
2018 - ChiCTR1800016968 China
Activematrix
Baylor College of Medicine
2022 Phase 4 NCT05297513 -
Acupuncture
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Shaozhou People's Hospital
2022 - ChiCTR2200063478 China
Taipei Medical University Hospital
2019 - NCT03801512 Taiwan
Adjunctive analgesics
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Adjunctive ANTI-depressants
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
AK1320 MS
Asahi Kasei Pharma Corporation
2020 Phase 1 NCT04483297 Canada
Alanine
University of California, Irvine
2025 - NCT06579391 United States
Allogen-LI
University of Southern California
2016 - NCT02932020 United States
Allograft
Mesoblast, Ltd.
2010 Phase 2 NCT01097486 United States
Alprostadil
Tokai University Hospital Department of Orthopaedic Surgery
2010 - JPRN-UMIN000005959 Japan
Amino acids
Wakayama Medical University
2018 - JPRN-UMIN000030881 Japan
Aminocaproic acid
National Heart, Lung, and Blood Institute (NHLBI)
2000 - NCT00320619 United States
Amniotic fluid allograft
University of Utah
2021 Phase 1/Phase 2 NCT04537026 United States
Apple watch and APP
Stanford University
2020 - NCT04379921 United States
Baclofen (baclofen TAB. 10MG) treatment
Yonsei University
2022 - NCT05392361 Korea, Republic of
BEE venom pharmacopuncture
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Bilateral transforaminal epidural steroid injections
Marshfield Clinic Research Foundation
2013 - NCT01995461 United States
Bioactive glass-ceramic spacer
BioAlpha Inc.
2010 - NCT03532945 -
Bone marrow concentrate
Stem Cures
2018 Phase 2/Phase 3 NCT04559295 United States
Botulinum toxin type A (nabota®) injection into THE gastrocnemius muscle
Yonsei University
2015 - NCT02444351 Korea, Republic of
Bupivacaine
2020 Phase 4 EUCTR2019-003590-25-NL Netherlands
Bupivacaine-epinephrine 0.25%-1:200,000 injectable solution plus clonidine
John O'Toole
2022 Phase 4 NCT05029726 United States
BupivacaïNE HCL 0,125% / sufentanil 50 µG flacon à 50 ML
2020 Phase 4 EUCTR2019-003590-25-NL Netherlands
Buprenorphine
Seoul National University Hospital
2015 Phase 4 NCT02416804 Korea, Republic of
Caudal epidural injection with celestone
Pain Management Center of Paducah
2007 Phase 0 NCT00370799 United States
Caudal epidural injection with depomedrol
Pain Management Center of Paducah
2007 Phase 0 NCT00370799 United States
Caudal epidural injection with generic celestone
Pain Management Center of Paducah
2007 Phase 0 NCT00370799 United States
Celebrex 200MG capsule
Seoul National University Bundang Hospital
2018 Phase 4 NCT03584074 -
Celecoxib
Department of Orthopedic Surgery Kobe University Graduate School of Medicine
2012 - JPRN-UMIN000007419 Japan
The First Affiliated Hospital of Chongqing Medical University
2020 Phase 0 ChiCTR2000028775 China
The Third Affiliated Hospital of Southern Medical University
2024 Phase 4 ChiCTR2400092866 China
University of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
2011 Phase 3 JPRN-UMIN000004825 Japan
Wang Jing Hospital, Chinese Academy of Traditional Chinese Medicine
2021 - ChiCTR2100046515 China
Centerpiece titanium plate
Xijing Hospital
2023 - NCT05786313 China
Cervical interbody fusion
Induce Biologics USA Inc.
2024 - NCT06000319 United States
Chuna manipulation
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2017 - NCT02975011 Korea, Republic of
Chuna manual medicine
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
Cilostazol
Juntendo University Department of Orthopaedic Surgery
2011 - JPRN-UMIN000006588 Japan
Creatinine
Nikaido Takuya
2020 - JPRN-jRCTs021200007 -
Cupping
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Darvocet
University of Rochester
2008 Phase 4 NCT00652093 United States
Decadron phosphate, injectable
Hospital for Special Surgery, New York
2017 Phase 4 NCT03245671 United States
Definity perflutren lipid microsphere ultrasound contrast
Medical University of South Carolina
2023 - NCT05530798 United States
Deksmedetomidiini
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Demineralized bone matrix
OhioHealth
2014 - NCT02070484 United States
Denosumab
The First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology
2021 Phase 4 ChiCTR2100053054 China
DEPO-medrol 40MG/ML suspension FOR injection
Hospital for Special Surgery, New York
2021 Phase 3 NCT05058287 United States
Depomedrol
Europainclinics z.ú.
2021 - NCT02459392 Czech Republic;Czechia
University of Southern California
2016 - NCT02932020 United States
Dexamethasone
Potsawat Surabotsopon
2024 Phase 4 NCT06367855 -
Dexamethasone 4 MG/ML injectable solution
Poznan University of Medical Sciences
2024 Phase 4 NCT06233617 Poland
Dexamethasone sodium phosphate
University of Utah
2021 Phase 1/Phase 2 NCT04537026 United States
Dexdor
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Dexmedetomidine
Vanderbilt University Medical Center
2009 Phase 4 NCT00808665 United States
Dexmedetomidine group
New York University School of Medicine
2010 - NCT01377623 United States
Yonsei University
2016 - NCT02902380 Korea, Republic of
Dexmedetomidine hydrochloride
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Dexmedetomidine injection
Poznan University of Medical Sciences
2024 Phase 4 NCT06233617 Poland
Dexmedetomidine with ropivacaine
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Diphenhydramine
University of Rochester
2008 Phase 4 NCT00638443 United States
Eaca
National Heart, Lung, and Blood Institute (NHLBI)
2000 - NCT00320619 United States
Elcatonin
Zhejiang province hospital of Chinese medicine
2024 Phase 0 ChiCTR2400083358 China
Electroacupuncture
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Epidural injection
Tel-Aviv Sourasky Medical Center
2016 Phase 2/Phase 3 NCT02725723 -
Epidural local anesthetic injection
University of Washington
2011 Phase 4 NCT01238536 United States
Epidural steroid (dexamethasone) injection
Keimyung University Dongsan Medical Center
2016 - NCT02838615 -
Epidural steroid injection
Coastal Orthopedics & Sports Medicine
2009 Phase 4 NCT00995371 United States
Hadassah Medical Organization
2013 Phase 4 NCT01934868 Israel
Hospital for Special Surgery, New York
2017 Phase 4 NCT03245671 United States
University of Washington
2011 Phase 4 NCT01238536 United States
Vertos Medical, Inc.
2014 - NCT02093520 United States
2011 - NCT01315145 United States
Epidural steroid with local anesthetic injection
University of Washington
2011 Phase 4 NCT01238536 United States
Epiduroscopy
Europainclinics z.ú.
2021 - NCT02459392 Czech Republic;Czechia
Erythropoietin
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
2017 - ChiCTR-INR-17012403 China
Esketamine hydrochloride
Helsinki Universiy Central Hospital
2012 Phase 4 EUCTR2012-000747-26-FI Finland
Essential amino acids
University of California, Irvine
2025 - NCT06579391 United States
Etoricoxib
Zhejiang province hospital of Chinese medicine
2024 Phase 0 ChiCTR2400083358 China
Fentanyl
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Forsteo
Department of Orthopaedics IKE
2011 Phase 4 EUCTR2011-002917-12-SE Sweden
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Forteo
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Gabapentin
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Gabapentin (neurontin® capsule 300MG) treatment
Yonsei University
2022 - NCT05392361 Korea, Republic of
Gelatin
Weifang People's Hospital
2023 - ChiCTR2300077538 China
2023 - ChiCTR2300076789 China
Goldic serum
Sutherland Medical Center
2020 Phase 4 NCT04492774 Poland
Group exercise: community setting
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Heparin
Seoul National University Bundang Hospital
2012 - NCT01522846 Korea, Republic of
Herbal medicine
Jaseng Hospital of Korean Medicine
2012 - NCT02257723 Korea, Republic of
Jaseng Medical Foundation
2019 - NCT03879447 Korea, Republic of
2017 - NCT02975011 Korea, Republic of
Hyaluronic acid
Europainclinics z.ú.
2021 - NCT02459392 Czech Republic;Czechia
Hydromorphone
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
I-factor
Sygehus Lillebaelt
2012 Phase 3 NCT01618435 Denmark
Individualized exercises: clinical setting
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Interleukin-6
Dept. of Orthopaedic Surgery, Graduate School of Medicine, Chiba University
2014 - JPRN-UMIN000015670 Japan
Kenalog injectable product
Hospital for Special Surgery, New York
2017 Phase 4 NCT03245671 United States
Ketamine
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
University of California, San Francisco
2023 Phase 3 NCT06140927 United States
University of Turku
2016 Phase 1;Phase 4 EUCTR2016-002887-14-FI Finland
Ketanest-S
Helsinki Universiy Central Hospital
2012 Phase 4 EUCTR2012-000747-26-FI Finland
University of Turku
2016 Phase 1;Phase 4 EUCTR2016-002887-14-FI Finland
Ketorolac
Hospital for Special Surgery, New York
2016 - NCT02700451 United States
Lidocaine hydrochloride, injectable
Stanford University
2021 Early Phase 1 NCT04992572 United States
Limaprost
Kansai LSS Forum
2014 - JPRN-UMIN000012918 Japan
Peking University Third Hospital
2023 Phase 4 ChiCTR2300076153 china
The Third Affiliated Hospital of Southern Medical University
2024 Phase 4 ChiCTR2400092866 China
University of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
2011 Phase 3 JPRN-UMIN000004825 Japan
Yungjin Pharm. Co., Ltd.
2013 Phase 4 NCT01888536 Korea, Republic of
Liposomal bupivacaine
Allina Health System
2019 Phase 4 NCT03745040 United States
University of Colorado, Denver
2019 Phase 2 NCT04066296 United States
Lobster device
Diametros Medical srl
2022 - NCT05587465 Italy
Lumbar epidural injection
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Lumbar interbody fusion
Induce Biologics USA Inc.
2024 - NCT06000319 United States
Lumbar interbody fusion with autograft
Mesoblast, Ltd.
2009 Phase 2 NCT00996073 United States
Lumbar interbody fusion with neofuse
Mesoblast, Ltd.
2009 Phase 2 NCT00996073 United States
Lumbar interlaminar epidural steroid injection
Emory University
2014 - NCT02103543 United States
Magnesium with ropivacaine
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Manual therapy
Sutherland Medical Center
2020 Phase 4 NCT04492774 Poland
Mastergraft granules
Mesoblast, Ltd.
2010 Phase 1/Phase 2 NCT01106417 Australia
Mecobalamin
Peking University Shougang Hospital
2023 Phase 4 ChiCTR2300073153 China
Wang Jing Hospital, Chinese Academy of Traditional Chinese Medicine
2021 - ChiCTR2100046515 China
Zhejiang province hospital of Chinese medicine
2024 Phase 0 ChiCTR2400083358 China
Metaxalone 640 MG oral tablet
Primus Pharmaceuticals
2023 Phase 4 NCT06157177 United States
Mild procedure
Vertos Medical, Inc.
2014 - NCT02093520 United States
Mirogabalin
Nikaido Takuya
2020 - JPRN-jRCTs021200007 -
Misoprostol
Dallas VA Medical Center
2019 - NCT04611464 United States
Modified-thoracolumbar interfascial plane block
Medipol University
2020 - NCT04189341 Turkey
Morphine PCA
University Hospital, Basel, Switzerland
2011 Phase 2/Phase 3 NCT01275547 Switzerland
Natural matrix protein (NMP) fibers
Induce Biologics USA Inc.
2024 - NCT06000319 United States
Neofuse
Mesoblast, Ltd.
2010 Phase 1/Phase 2 NCT01106417 Australia
2010 Phase 2 NCT01097486 United States
2007 Phase 1/Phase 2 NCT00549913 United States
Nicardipine
Yonsei University
2012 Phase 4 NCT02271191 -
Normal saline
John O'Toole
2022 Phase 4 NCT05029726 United States
Potsawat Surabotsopon
2024 Phase 4 NCT06367855 -
Seoul National University Hospital
2019 Phase 4 NCT04401735 Korea, Republic of
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
2017 - ChiCTR-INR-17012403 China
Xuanwu Hospital Capital Medical University
2023 - ChiCTR2500095855 China
Nsaids
Higashi Ohmiya general hospital
2010 - JPRN-UMIN000005382 Japan
Michael Schneider, DC, PhD
2013 - NCT01943435 United States
Nikaido Takuya
2020 - JPRN-jRCTs021200007 -
Nucel
OhioHealth
2014 - NCT02070484 United States
Oksikodoni
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Opana
University of Rochester
2008 Phase 4 NCT00652093 United States
Oxanest
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Oxycodone hydrochloride
University of Turku
2015 Phase 1;Phase 4 EUCTR2014-003252-31-FI Finland
Oxycodone orion
University of Turku
2016 Phase 1;Phase 4 EUCTR2016-002887-14-FI Finland
Oxygen
Johns Hopkins University
2017 Early Phase 1 NCT03088306 United States
Yonsei University
2016 - NCT02625194 Korea, Republic of
Oxytocin nasal spray
Zhejiang University
2025 Phase 2 NCT06945926 China
Ozone
Shaozhou People's Hospital
2022 - ChiCTR2200063478 China
Parathyroid hormone
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Percutaneous lumbar decompression
Vertos Medical, Inc.
2011 - NCT01315145 United States
Phosphate
Histograft Co., Ltd.
2023 - NCT06365307 Russian Federation
Physical therapy
Emory University
2014 - NCT02103543 United States
Platelet rich plasma
Taipei Medical University Hospital
2019 - NCT03801512 Taiwan
PLF with autograft
Mesoblast, Ltd.
2008 Phase 1/Phase 2 NCT00810212 United States
PLF with neofuse
Mesoblast, Ltd.
2008 Phase 1/Phase 2 NCT00810212 United States
Polydeoxyribonucleotides
Seoul National University Hospital
2019 Phase 4 NCT04401735 Korea, Republic of
Posterolateral spinal fusion with instrumentation
Mesoblast, Ltd.
2007 Phase 1/Phase 2 NCT00549913 United States
Predinose oral
Federal University of São Paulo
2011 - NCT01456377 Brazil
Pregabalin
Department of Orthopedic Surgery Kobe University Graduate School of Medicine
2012 - JPRN-UMIN000007419 Japan
Northwestern University
2009 Phase 4 NCT00908375 United States
The First Affiliated Hospital of Chongqing Medical University
2020 Phase 0 ChiCTR2000028775 China
University of Rochester
2008 Phase 4 NCT00638443 United States
Yungjin Pharm. Co., Ltd.
2013 Phase 4 NCT01888536 Korea, Republic of
Pregabalin 75MG
Seoul National University Bundang Hospital
2018 Phase 4 NCT03584074 -
Prolotherapy solution OF 20% dextrose
Hadassah Medical Organization
2013 Phase 4 NCT01934868 Israel
Propofol
Beijing Municipal Geriatric Medical Research Center
2022 Phase 0 ChiCTR2200058808 China
Propofol injection
Stanford University
2021 Early Phase 1 NCT04992572 United States
Remifentanil
Peking University Third Hospital
2012 - ChiCTR-TRC-13003639 China
Yonsei University
2010 Phase 4 NCT01052324 Korea, Republic of
Rhpth
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Rocuronium bromide
Zheng Guo
2022 Early Phase 1 NCT05619848 China
Ropivacaine
Beijing Beijing Coal Group General Hospital
2023 - ChiCTR2300076493 China
Binzhou Medical University Hospital
2022 - ChiCTR2200061908 China
Higashi Ohmiya general hospital
2010 - JPRN-UMIN000005382 Japan
Second Hospital of Lanzhou University
2023 Phase 0 ChiCTR2300070414 China
Ropivacaine hydrochloride injection
Ilse van de Wijgert
2022 Phase 4 NCT05345249 Netherlands
Ropivacaine plus normal saline
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Ropivacaine, epinephrine, clonidine, and ketorolac injection cocktail
University of Maryland, Baltimore
2025 Phase 1/Phase 2 NCT06447194 United States
S-ketamine & midazolam
University Hospital, Basel, Switzerland
2011 Phase 2/Phase 3 NCT01275547 Switzerland
Selective nerve root block
The Cleveland Clinic
2018 Phase 4 NCT03801356 United States
Selexipag
Nippon Shinyaku Co., Ltd.
2018 Phase 2 JPRN-jRCT2080223810 Japan
Sevoflurane
Saglik Bilimleri Universitesi
2023 - NCT06558695 Turkey
Sodium chloride
Ilse van de Wijgert
2022 Phase 4 NCT05345249 Netherlands
Steroid
Taipei Medical University Hospital
2019 - NCT03801512 Taiwan
Steroid injections
Sutherland Medical Center
2020 Phase 4 NCT04492774 Poland
Sufentanil
Beijing Beijing Coal Group General Hospital
2023 - ChiCTR2300076493 China
Sugar pill
Northwestern University
2009 Phase 4 NCT00908375 United States
Surgical espb
Bursa City Hospital
2022 - NCT05630404 Turkey
Synthetic osteoplastic material based ON ß-TCP or bone autograft
Histograft Co., Ltd.
2023 - NCT06365307 Russian Federation
Teicoplanin
Bezmialem Vakif University
2020 Phase 3 NCT04341831 -
Teriparatide
Middelfart Rygsektor
2012 Phase 2 EUCTR2011-006152-36-DK Denmark
Qilu Hospital of Shandong University
2018 - ChiCTR1800016968 China
University Hospital, Linkoeping
2012 Phase 4 NCT02090244 Sweden
Therm-apptm TH, thermographic camera
Tel-Aviv Sourasky Medical Center
2016 Phase 2/Phase 3 NCT02725723 -
Titanium
Farhan Karim
2021 - NCT05023733 United States
Titanium cage
BioAlpha Inc.
2010 - NCT03532945 -
Tiva
Saglik Bilimleri Universitesi
2023 - NCT06558695 Turkey
Tramadol
Seoul National University Hospital
2015 Phase 4 NCT02416804 Korea, Republic of
Tramadol with ropivacaine
Aristotle University Of Thessaloniki
2020 Phase 4 NCT04391855 Greece
Tranexamic acid
Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region
2022 Phase 4 ChiCTR2200063132 China
Massachusetts General Hospital
2012 Phase 4 NCT02063035 United States
Tranexamic acid 100 MG/ML
Hospital for Special Surgery, New York
2018 Phase 3 NCT03553186 United States
Transdermal fentanyl matrix, gabapentin
Seoul National University Hospital
2010 Phase 4 NCT01127100 Korea, Republic of
Transforaminal epidural injection
Eduard Verheijen
2020 - NCT04540068 Netherlands
Triamcinolone acetonide and normal saline solution
Navamindradhiraj University
2016 - NCT02939482 Thailand
Tylenol
Peking University Third Hospital
2019 - NCT04042948 China
Ulinastatin
Xuanwu Hospital Capital Medical University
2023 - ChiCTR2500095855 China
US guided espb
Bursa City Hospital
2022 - NCT05630404 Turkey
Vancomycin
Department of Spinal Surgery, Shenzhen Second People's Hospital
2023 Phase 0 ChiCTR2300073231 China
Taipei Veterans General Hospital, Taiwan
2018 - NCT03883022 Taiwan
Vivigen cellular bone matrix
Ohio State University
2019 Phase 4 NCT04007094 United States
Wound topically irrigated with 500MG TXA
Peking Union Medical College Hospital
2017 - NCT03011866 -