95. 自己免疫性肝炎 Disease details / Clinical trials / Drug dev / DR info

Abatacept
   Stuart Knechtle, M.D.
      2020   Phase 1   NCT04203875   United States
ANTI-baffr antibody
   Novartis Farmacéutica S.A
      2017   Phase 2;Phase 3   EUCTR2017-001555-32-ES   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
   Novartis Pharma AG
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-NL   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-GB   Argentina;Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-DK   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-DE   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-BE   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 2;Phase 3   EUCTR2017-001555-32-SE   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
Azathioprine
   Leiden university medical centre
      2018   Phase 4   EUCTR2016-001038-91-BE   Belgium;Netherlands
      2016   Phase 4   EUCTR2016-001038-91-NL   Netherlands
   Radboud University Medical Center
      2017   Phase 4   NCT02900443   Belgium;Netherlands
   University of Sao Paulo General Hospital
      2003   Phase 4   NCT02463331   -
   Veloxis Pharmaceuticals
      2007   Phase 2   NCT00608894   Canada;United States
Azathioprine + prednisolone
   Institute of Liver and Biliary Sciences, India
      2024   Phase 2/Phase 3   NCT06650124   -
Belimumab
   University Health Network, Toronto
      2024   Phase 2   NCT06381453   Canada
Budesonid
   Umeå University Hospital
      2020   Phase 4   EUCTR2018-003381-14-SE   Sweden
Budesonide
   Dr. Falk Pharma GmbH
      2001   Phase 2/Phase 3   NCT00838214   Germany
   Mayo Clinic
      2007   -   NCT00587119   United States
Calcium
   Juntendo University School of Medicine
      2014   -   JPRN-UMIN000013659   Japan
Cannabidiol
   Stero Biotechs Ltd.
      2019   Phase 2   NCT04129489   Israel
Chloroquine diphosphate
   University of Sao Paulo General Hospital
      2003   Phase 4   NCT02463331   -
Chloroquine diphosphate 250MG
   University of Sao Paulo General Hospital
      2002   Phase 4   NCT01980745   Brazil
Collection OF samples
   Institut National de la Santé Et de la Recherche Médicale, France
      2021   -   NCT04902807   -
Cyclosporin A
   West China Hospital
      2021   Phase 4   NCT04376528   China
Cyclosporine-A
   Tehran University of Medical Sciences
      2005   Phase 3   NCT01170351   Iran, Islamic Republic of
Denosumab
   Juntendo University School of Medicine
      2014   -   JPRN-UMIN000013659   Japan
Dietary assignment
   Indiana University
      2023   -   NCT06250309   United States
Efalizumab
   Merck Serono International S.A.
      2009   -   EUCTR2007-001377-28-PT   Austria;France;Germany;Netherlands;Portugal
      2008   -   EUCTR2007-001377-28-NL   Austria;France;Germany;Netherlands;Portugal
      2008   Phase 4   EUCTR2007-001377-28-FR   Austria;France;Germany;Netherlands;Portugal
      2008   -   EUCTR2007-001377-28-DE   Austria;France;Germany;Netherlands;Portugal
      2008   -   EUCTR2007-001377-28-AT   Austria;France;Germany;Netherlands;Portugal
Erythropoietin
   Northwestern University
      2019   Early Phase 1   NCT03842254   United States
High protein high fiber diet
   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
      2012   -   NCT01655121   Mexico
HR19042 capsule
   Jiangsu HengRui Medicine Co., Ltd.
      2023   Phase 1   NCT06922305   China
HR19042 capsules
   Jiangsu HengRui Medicine Co., Ltd.
      2022   Phase 2   NCT05476900   China
Ianalumab
   Novartis Pharma AG
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-NL   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-GB   Argentina;Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-DK   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-DE   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-CZ   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-BE   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 2;Phase 3   EUCTR2017-001555-32-SE   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
IGG IL2/RO7049665
   F. HOFFMANN - LA ROCHE LTD.
      2021   Phase 2   EUCTR2020-003990-23-IT   Australia;Canada;Germany;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
   F. Hoffmann-La Roche Ltd
      2021   Phase 2   EUCTR2020-003990-23-PT   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
      2021   Phase 2   EUCTR2020-003990-23-NL   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
      2021   Phase 2   EUCTR2020-003990-23-DE   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
Infliximab
   University Medical Centre Hamburg-Eppendorf
      2018   Phase 2   EUCTR2017-003311-19-DE   Germany
Interleukin 2
   Assistance Publique - Hôpitaux de Paris
      2014   Phase 2   NCT01988506   France
JKB-122
   TaiwanJ Pharmaceuticals Co., Ltd
      2020   Phase 2   NCT04371718   -
      2016   Phase 2   NCT02556372   United States
JKB-122 IN capsule or tablet form
   TaiwanJ Pharmaceuticals Co., Ltd
      2020   Phase 1   NCT04313205   -
Methylprednisolone and azathioprine
   Xiaoli Fan
      2021   Phase 4   NCT04933292   China
Methylprednisolone and mycophenolate mofetil
   Xiaoli Fan
      2021   Phase 4   NCT04933292   China
Minodronic acid
   Juntendo University School of Medicine
      2014   -   JPRN-UMIN000013659   Japan
Mycophenolate mofeti
   Leiden university medical centre
      2018   Phase 4   EUCTR2016-001038-91-BE   Belgium;Netherlands
      2016   Phase 4   EUCTR2016-001038-91-NL   Netherlands
Mycophenolate mofetil
   Institute of Liver and Biliary Sciences, India
      2024   Phase 2/Phase 3   NCT06650124   -
   Leiden university medical centre
      2018   Phase 4   EUCTR2016-001038-91-BE   Belgium;Netherlands
      2016   Phase 4   EUCTR2016-001038-91-NL   Netherlands
   Radboud University Medical Center
      2017   Phase 4   NCT02900443   Belgium;Netherlands
   West China Hospital
      2021   Phase 4   NCT04376528   China
Orbcel-C
   University of Birmingham
      2018   Phase 1/Phase 2   NCT02997878   United Kingdom
Plasma exchange
   Institute of Liver and Biliary Sciences, India
      2025   -   NCT06855667   India
Prednisolon
   Umeå University Hospital
      2020   Phase 4   EUCTR2018-003381-14-SE   Sweden
Prednisolone sodium succinate
   Leiden university medical centre
      2018   Phase 4   EUCTR2016-001038-91-BE   Belgium;Netherlands
      2016   Phase 4   EUCTR2016-001038-91-NL   Netherlands
Prednisone
   Dr. Falk Pharma GmbH
      2001   Phase 2/Phase 3   NCT00838214   Germany
   University of Sao Paulo General Hospital
      2003   Phase 4   NCT02463331   -
Raptiva 100 MG/ML powder and solvent FOR solution FOR injection
   Merck Serono International S.A.
      2009   -   EUCTR2007-001377-28-PT   Austria;France;Germany;Netherlands;Portugal
      2008   -   EUCTR2007-001377-28-NL   Austria;France;Germany;Netherlands;Portugal
      2008   Phase 4   EUCTR2007-001377-28-FR   Austria;France;Germany;Netherlands;Portugal
      2008   -   EUCTR2007-001377-28-DE   Austria;France;Germany;Netherlands;Portugal
      2008   -   EUCTR2007-001377-28-AT   Austria;France;Germany;Netherlands;Portugal
Regulatory T cells
   Nanjing Medical University
      2016   Phase 1/Phase 2   NCT02704338   -
Risedronic acid
   Juntendo University School of Medicine
      2014   -   JPRN-UMIN000013659   Japan
RO7049665
   Hoffmann-La Roche
      2021   Phase 2   NCT04790916   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;Portugal;United Kingdom
RO7049665/IGG-IL2/ IGG-IL2nd2
   F. HOFFMANN - LA ROCHE LTD.
      2021   Phase 2   EUCTR2020-003990-23-IT   Australia;Canada;Germany;Italy;Korea, Democratic People's Republic of;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
   F. Hoffmann-La Roche Ltd
      2021   Phase 2   EUCTR2020-003990-23-PT   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
      2021   Phase 2   EUCTR2020-003990-23-NL   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
      2021   Phase 2   EUCTR2020-003990-23-DE   Australia;Canada;Germany;Italy;Korea, Republic of;Netherlands;New Zealand;Portugal;United Kingdom
Siplizumab
   Elizabeth C. Verna
      2024   Phase 1   NCT06455280   United States
Spif
   Christopher O'Brien, MD
      2014   Phase 1   NCT02239562   United States
Steroid
   Institute of Liver and Biliary Sciences, India
      2025   -   NCT06855667   India
Synthetic preimplantation factor
   Christopher O'Brien, MD
      2019   Phase 2   NCT03593460   -
Tacrolimus
   Hiroshima University Hospital
      2019   -   JPRN-UMIN000030743   Japan
   Veloxis Pharmaceuticals
      2007   Phase 2   NCT00608894   Canada;United States
Treatment with azathioprin
   Rigshospitalet, Denmark
      2005   Phase 4   NCT00687180   Denmark
Treatment with mycophenolat mofetil
   Rigshospitalet, Denmark
      2005   Phase 4   NCT00687180   Denmark
Ursodeoxycholic acid combination OF immunosuppressive agents
   Xiaoli Fan
      2016   -   NCT02936596   China
Various
   Umeå University Hospital
      2020   Phase 4   EUCTR2018-003381-14-SE   Sweden
VAY736
   Novartis Farmacéutica S.A
      2017   Phase 2;Phase 3   EUCTR2017-001555-32-ES   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
   Novartis Pharma AG
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-NL   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-GB   Argentina;Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-DK   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-DE   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-CZ   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2018   Phase 2;Phase 3   EUCTR2017-001555-32-BE   Argentina;Belgium;Canada;Czech Republic;Czechia;Denmark;Germany;Japan;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
      2017   Phase 2;Phase 3   EUCTR2017-001555-32-SE   Belgium;Canada;Czech Republic;Denmark;Germany;Japan;Netherlands;Spain;Sweden;Switzerland;United Kingdom;United States
   Novartis Pharmaceuticals
      2018   Phase 2/Phase 3   NCT03217422   Argentina;Belgium;Canada;Czechia;Denmark;Germany;Japan;Netherlands;Singapore;Spain;Sweden;Switzerland;United Kingdom;United States
Vitamin D
   Juntendo University School of Medicine
      2014   -   JPRN-UMIN000013659   Japan
Zetomipzomib IN OPEN-label extension
   Kezar Life Sciences, Inc.
      2023   Phase 2   NCT05569759   United States
Zoledronic acid
   Hyogo college of medicine
      2018   -   JPRN-UMIN000031353   Japan