CK-2017357
( DrugBank: - / KEGG DRUG: - )
1 disease
| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 2 | 筋萎縮性側索硬化症 | 25 |
2. 筋萎縮性側索硬化症
臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225
Showing 1 to 10 of 25 trials
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2016-002629-13-BE (EUCTR) | 04/09/201720170904 | 21/04/201720170421 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 19.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 19.1;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;France;United States;Canada;Spain;Belgium;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 2 | EUCTR2016-002629-13-PT (EUCTR) | 28/08/201720170828 | 04/05/201720170504 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders ;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | France;United States;Portugal;Canada;Belgium;Spain;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 3 | EUCTR2016-002629-13-NL (EUCTR) | 07/06/201720170607 | 14/03/201720170314 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 19.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 19.1;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;France;United States;Canada;Belgium;Spain;Ireland;Germany;Netherlands;Italy;United Kingdom | ||
| 4 | EUCTR2016-002629-13-GB (EUCTR) | 05/06/201720170605 | 09/02/201820180209 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders ;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;France;United States;Canada;Belgium;Spain;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 5 | EUCTR2016-002629-13-FR (EUCTR) | 22/05/201720170522 | 16/05/201720170516 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders ;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;United States;France;Canada;Belgium;Spain;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 6 | EUCTR2016-002629-13-ES (EUCTR) | 12/04/201720170412 | 10/03/201720170310 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 19.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 19.1;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;France;United States;Canada;Belgium;Spain;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 7 | EUCTR2016-002629-13-IT (EUCTR) | 28/03/201720170328 | 20/01/202120210120 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | CYTOKINETICS, INC. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;France;United States;Canada;Spain;Belgium;Ireland;Netherlands;Germany;United Kingdom;Italy | ||
| 8 | EUCTR2016-002629-13-IE (EUCTR) | 28/02/201720170228 | 25/11/201620161125 | An Open-Label Extension Study for Patients Who Completed VITALITY-ALS (CY 4031) | A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) who Completed VITALITY-ALS (CY 4031) - VIGOR-ALS A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Portugal;France;United States;Canada;Belgium;Spain;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 9 | EUCTR2014-005413-23-IE (EUCTR) | 30/11/201620161130 | 10/09/201520150910 | Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year (VITALITY-ALS) Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a ... | A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, Study to Evaluate the Safety, Tolerability and Efficacy of Tirasemtiv in Patients with Amyotrophic Lateral Sclerosis (ALS) A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | Cytokinetics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 600 | Phase 3 | Portugal;France;United States;Canada;Belgium;Spain;Ireland;Netherlands;Germany;Italy;United Kingdom | ||
| 10 | EUCTR2014-005413-23-IT (EUCTR) | 30/05/201620160530 | 16/02/201820180216 | Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year (VITALITY-ALS) Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a ... | A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, Study to Evaluate the Safety, Tolerability and Efficacy of Tirasemtiv in Patients with Amyotrophic Lateral Sclerosis (ALS) - - A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ... | Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive name: 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2(3H)-one Product Name: Tirasemtiv Product Code: CK-2017357 INN or Proposed INN: Tirasemtiv Other descriptive nam ... | CYTOKINETICS, INC. | NULL | Not Recruiting | Female: yes Male: yes | 600 | Phase 3 | Portugal;France;United States;Canada;Belgium;Spain;Ireland;Netherlands;Germany;United Kingdom;Italy |