Glycerol

( DrugBank: Glycerol / KEGG DRUG: Glycerin )

5 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	1
13	多発性硬化症／視神経脊髄炎	3
79	家族性高コレステロール血症（ホモ接合体）	3

告示番号	疾患名（ページ内リンク）	臨床試験数
316	カルニチン回路異常症	1
317	三頭酵素欠損症	1

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02046434 (ClinicalTrials.gov)	January 2014	23/1/2014	Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain	Phenylbutyrate Response As a Biomarker for Alpha-Synuclein Clearance From Brain	Parkinson's Disease	Drug: Glycerol Phenylbutyrate	University of Colorado, Denver	NULL	Active, not recruiting	21 Years	80 Years	All	40	Phase 1	United States

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13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2009-011585-28-FR (EUCTR)	21/10/2009	05/08/2009	A randomised double-blind placebo-controlled phase IIa study of orally administered BGC20-0134 in pa ...	A randomised double-blind placebo-controlled phase IIa study of orally administered BGC20-0134 in pa ...	relapsing-remitting multiple sclerosis MedDRA version: 9.1;Level: LLT;Classification code 10063399;T ...	Product Name: BCG20-0134 Product Code: BCG20-0134 Other descriptive name: Glycerol-1,3-didecanoate-2-o ...	BTG International Ltd	NULL	Authorised-recruitment may be ongoing or finished	Female: yes Male: yes	166	Phase 2	Germany;Belgium;France;Spain
2	EUCTR2009-011585-28-DE (EUCTR)	08/10/2009	07/07/2009	Early phase clinical trial to evaluate the effectiveness and safety of a new orally administered dru ...	A randomised double-blind placebo-controlled phase IIa study of orally administered BGC20-0134 in pa ...	relapsing-remitting multiple sclerosis MedDRA version: 14.0;Level: PT;Classification code 10063399;T ...	Product Name: BCG20-0134 Product Code: BCG20-0134 Other descriptive name: Glycerol-1,3-didecanoate-2-o ...	BTG International Ltd	NULL	Not Recruiting	Female: yes Male: yes	184	Phase 2	France;European Union;Spain;Belgium;Russian Federation;Germany
3	EUCTR2009-011585-28-BE (EUCTR)	28/09/2009	13/07/2009	Early phase clinical trial to evaluate the effectiveness and safety of a new orally administered dru ...	A randomised double-blind placebo-controlled phase IIa study of orally administered BGC20-0134 in pa ...	relapsing-remitting multiple sclerosis MedDRA version: 14.0;Level: PT;Classification code 10063399;T ...	Product Name: BCG20-0134 Product Code: BCG20-0134 Other descriptive name: Glycerol-1,3-didecanoate-2-o ...	BTG International Ltd	NULL	Not Recruiting	Female: yes Male: yes	184	Phase 2	France;European Union;Spain;Belgium;Russian Federation;Germany

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79. 家族性高コレステロール血症（ホモ接合体）

臨床試験数 : 145 / 薬物数 : 114 - (DrugBank : 26) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 17

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-003998-28-NL (EUCTR)	28/02/2012	14/11/2011	Effect of CER-001 on blockage of arteries (plaque) in subjects with homozygous familial hypercholest ...	Modifying Orphan Disease Evaluation (MODE) Study: A Multicenter, Open-Label Study of the Effects of ...	homozygous familial hypercholesterolemia MedDRA version: 16.0;Level: LLT;Classification code 1002060 ...	Product Name: Recombinant Human Apolipoprotein A-I/Phospholipids Complex Product Code: CER-001 Other d ...	Cerenis Therapeutics	NULL	Not Recruiting	Female: yes Male: yes	30		France;United States;Canada;Netherlands;Italy;United Kingdom
2	EUCTR2011-003998-28-IT (EUCTR)	16/02/2012	08/03/2012	Effect of CER-001 on blockage of arteries (plaque) in subjects with homozygous familial hypercholest ...	Modifying Orphan Disease Evaluation (MODE) Study: A Multicenter, Open-Label Study of the Effects of ...	Homozygous familial hypercholesterolemia MedDRA version: 15.1;Level: SOC;Classification code 1002743 ...	Product Name: Recombinant Human Apolipoprotein Product Code: CER-001 Other descriptive name: Recombina ...	CERENIS THERAPEUTICS SA	NULL	Not Recruiting	Female: yes Male: yes	30		United States;Canada;Netherlands;United Kingdom;Italy
3	EUCTR2011-003998-28-GB (EUCTR)	24/01/2012	19/10/2011	Effect of CER-001 on blockage of arteries (plaque) in subjects with homozygous familial hypercholest ...	Modifying Orphan Disease Evaluation (MODE) Study: A Multicenter, Open-Label Study of the Effects of ...	homozygous familial hypercholesterolemia MedDRA version: 15.0;Level: LLT;Classification code 1002060 ...	Product Name: Recombinant Human Apolipoprotein A-I/Phospholipids Complex Product Code: CER-001 INN or ...	Cerenis Therapeutics	NULL	Not Recruiting	Female: yes Male: yes	30	Phase 2	United States;Canada;Netherlands;Italy;United Kingdom

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316. カルニチン回路異常症

臨床試験数 : 4 / 薬物数 : 10 - (DrugBank : 4) / 標的遺伝子数 : 2 - 標的パスウェイ数 : 11

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02517307 (ClinicalTrials.gov)	February 2016	2/7/2015	Fatty Acid Oxidation Defects and Insulin Sensitivity	Role of Fatty Acid Oxidation Defects in Insulin Sensitivity	Very Long-chain Acyl-CoA Dehydrogenase Deficiency;Trifunctional Protein Deficiency;Long-chain 3-hydr ...	Drug: Intralipid/Heparin;Drug: Glycerol/Saline;Drug: Hyperinsulinemic euglycemic clamp	Oregon Health and Science University	NULL	Completed	18 Years	N/A	All	52	N/A	United States

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317. 三頭酵素欠損症

臨床試験数 : 4 / 薬物数 : 9 - (DrugBank : 4) / 標的遺伝子数 : 1 - 標的パスウェイ数 : 1

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02517307 (ClinicalTrials.gov)	February 2016	2/7/2015	Fatty Acid Oxidation Defects and Insulin Sensitivity	Role of Fatty Acid Oxidation Defects in Insulin Sensitivity	Very Long-chain Acyl-CoA Dehydrogenase Deficiency;Trifunctional Protein Deficiency;Long-chain 3-hydr ...	Drug: Intralipid/Heparin;Drug: Glycerol/Saline;Drug: Hyperinsulinemic euglycemic clamp	Oregon Health and Science University	NULL	Completed	18 Years	N/A	All	52	N/A	United States

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