DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway💬 Info on mouse-over

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151 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
4	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
5	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
6	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
7	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
8	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
9	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
10	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
11	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
12	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
14	Adrenergic signaling in cardiomyocytes 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
15	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D00639 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
16	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D08215 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
17	African trypanosomiasis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
18	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
19	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
20	AGE-RAGE signaling pathway in diabetic complications 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
21	AGE-RAGE signaling pathway in diabetic complications 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
22	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
23	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
24	Alcoholism 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
25	Alcoholism 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
26	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
27	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
28	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
29	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D01115 💬	Eplerenone	[4] 75, 113, 210, 215 💬
30	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D00443 💬	Spironolactone	[7] 58, 67, 86, 113, 210, 218, 225 💬
31	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
32	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
33	Alzheimer disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
34	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
35	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
36	Alzheimer disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
37	Alzheimer disease 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
38	Alzheimer disease 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
39	Alzheimer disease 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
40	Alzheimer disease 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
41	Alzheimer disease 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
42	Amoebiasis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
43	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
44	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
45	Amphetamine addiction 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
46	Amphetamine addiction 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
47	Amphetamine addiction 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
48	Amphetamine addiction 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
49	Amphetamine addiction 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
50	AMPK signaling pathway 💬	[1] ADRA1A 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
51	AMPK signaling pathway 💬	[1] ADRA1A 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
52	AMPK signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
53	AMPK signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
54	Amyotrophic lateral sclerosis 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
55	Amyotrophic lateral sclerosis 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
56	Amyotrophic lateral sclerosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
57	Amyotrophic lateral sclerosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
58	Amyotrophic lateral sclerosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
59	Amyotrophic lateral sclerosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
60	Antifolate resistance 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
61	Apelin signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
62	Apelin signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
63	Apelin signaling pathway 💬	[1] CCN2 💬	D10969 💬	Pamrevlumab	[2] 85, 113 💬
64	Apelin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
65	Apelin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
66	Arachidonic acid metabolism 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
67	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
68	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
69	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
70	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
71	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
72	Arrhythmogenic right ventricular cardiomyopathy 💬	[1] DMD 💬	D11988 💬	Casimersen	[1] 113 💬
73	Arrhythmogenic right ventricular cardiomyopathy 💬	[1] DMD 💬	D10114 💬	Drisapersen	[1] 113 💬
74	Arrhythmogenic right ventricular cardiomyopathy 💬	[1] DMD 💬	D09900 💬	Eteplirsen	[1] 113 💬
75	Arrhythmogenic right ventricular cardiomyopathy 💬	[1] DMD 💬	D11707 💬	Golodirsen	[1] 113 💬
76	Arrhythmogenic right ventricular cardiomyopathy 💬	[1] DMD 💬	D11528 💬	Viltolarsen	[1] 113 💬
77	Autophagy - animal 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
78	Autophagy - animal 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
79	Axon guidance 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
80	Axon guidance 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
81	Axon guidance 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
82	B cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
83	B cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
84	B cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
85	Breast cancer 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
86	Breast cancer 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
87	Breast cancer 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
88	C-type lectin receptor signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
89	C-type lectin receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
90	C-type lectin receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
91	C-type lectin receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
92	C-type lectin receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
93	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
94	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
95	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
96	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
97	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
98	Calcium signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
99	Calcium signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
100	Calcium signaling pathway 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
101	Calcium signaling pathway 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
102	Calcium signaling pathway 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
103	Calcium signaling pathway 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
104	Calcium signaling pathway 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
105	Calcium signaling pathway 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
106	Calcium signaling pathway 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
107	Calcium signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
108	Calcium signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
109	Calcium signaling pathway 💬	[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
110	Calcium signaling pathway 💬	[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
111	Calcium signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
112	Calcium signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
113	Calcium signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
114	Calcium signaling pathway 💬	[1] TBXA2R 💬	D04500 💬	Ifetroban	[3] 51, 86, 113 💬
115	cAMP signaling pathway 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
116	cAMP signaling pathway 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
117	cAMP signaling pathway 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
118	cAMP signaling pathway 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
119	cAMP signaling pathway 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
120	cAMP signaling pathway 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
121	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
122	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
123	cAMP signaling pathway 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
124	cAMP signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
125	cAMP signaling pathway 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
126	cAMP signaling pathway 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
127	Cellular senescence 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
128	Cellular senescence 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
129	Cellular senescence 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
130	Cellular senescence 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
131	cGMP-PKG signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
132	cGMP-PKG signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
133	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬	D00514 💬	Dexmedetomidine	[12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
134	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬	D01205 💬	Dexmedetomidine	[12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
135	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
136	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
137	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
138	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
139	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
140	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
141	cGMP-PKG signaling pathway 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
142	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
143	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
144	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
145	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
146	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D02008 💬	Tadalafil	[7] 6 , 51, 75, 84, 86, 113, 210 💬
147	cGMP-PKG signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
148	cGMP-PKG signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
149	cGMP-PKG signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
150	Chagas disease 💬	[1] ACE 💬	D00621 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
151	Chagas disease 💬	[1] ACE 💬	D07892 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
152	Chagas disease 💬	[1] ACE 💬	D00362 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
153	Chagas disease 💬	[1] ACE 💬	D08131 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
154	Chagas disease 💬	[1] ACE 💬	D00624 💬	Perindopril	[3] 113, 167, 222 💬
155	Chagas disease 💬	[1] ACE 💬	D03753 💬	Perindopril	[3] 113, 167, 222 💬
156	Chagas disease 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
157	Chagas disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
158	Chagas disease 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
159	Chemical carcinogenesis 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
160	Chemical carcinogenesis 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
161	Chemical carcinogenesis 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
162	Chemical carcinogenesis 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
163	Chemical carcinogenesis 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
164	Circadian entrainment 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
165	Circadian entrainment 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
166	Circadian rhythm 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
167	Circadian rhythm 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
168	Cocaine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
169	Cocaine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
170	Cocaine addiction 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
171	Cocaine addiction 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
172	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00621 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
173	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D07892 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
174	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00362 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
175	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D08131 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
176	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00624 💬	Perindopril	[3] 113, 167, 222 💬
177	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D03753 💬	Perindopril	[3] 113, 167, 222 💬
178	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
179	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
180	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
181	Coronavirus disease - COVID-19 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
182	Coronavirus disease - COVID-19 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
183	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
184	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
185	Cortisol synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
186	Cushing syndrome 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
187	Cushing syndrome 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
188	Cushing syndrome 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
189	Cytokine-cytokine receptor interaction 💬	[1] CSF3R 💬	D03235 💬	Filgrastim	[33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
190	Cytokine-cytokine receptor interaction 💬	[1] GHR 💬	D02691 💬	Somatotropin	[20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
191	Cytokine-cytokine receptor interaction 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
192	Cytokine-cytokine receptor interaction 💬	[1] MSTN 💬	D11047 💬	Domagrozumab	[1] 113 💬
193	Cytosolic DNA-sensing pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
194	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00621 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
195	Diabetic cardiomyopathy 💬	[1] ACE 💬	D07892 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
196	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00362 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
197	Diabetic cardiomyopathy 💬	[1] ACE 💬	D08131 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
198	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00624 💬	Perindopril	[3] 113, 167, 222 💬
199	Diabetic cardiomyopathy 💬	[1] ACE 💬	D03753 💬	Perindopril	[3] 113, 167, 222 💬
200	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
201	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
202	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
203	Diabetic cardiomyopathy 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
204	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
205	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
206	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
207	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
208	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
209	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
210	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
211	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
212	Dilated cardiomyopathy 💬	[1] DMD 💬	D11988 💬	Casimersen	[1] 113 💬
213	Dilated cardiomyopathy 💬	[1] DMD 💬	D10114 💬	Drisapersen	[1] 113 💬
214	Dilated cardiomyopathy 💬	[1] DMD 💬	D09900 💬	Eteplirsen	[1] 113 💬
215	Dilated cardiomyopathy 💬	[1] DMD 💬	D11707 💬	Golodirsen	[1] 113 💬
216	Dilated cardiomyopathy 💬	[1] DMD 💬	D11528 💬	Viltolarsen	[1] 113 💬
217	Dopaminergic synapse 💬	[2] GRIN2A, GRIN2B 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
218	Dopaminergic synapse 💬	[2] GRIN2A, GRIN2B 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
219	Dopaminergic synapse 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
220	Dopaminergic synapse 💬	[3] PPP3CA, PPP3CB, PPP3CC 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
221	Dopaminergic synapse 💬	[3] PPP3CA, PPP3CB, PPP3CC 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
222	Dopaminergic synapse 💬	[3] PPP3CA, PPP3CB, PPP3CC 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
223	Dopaminergic synapse 💬	[1] SCN1A 💬	D00639 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
224	Dopaminergic synapse 💬	[1] SCN1A 💬	D08215 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
225	Dopaminergic synapse 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
226	Dopaminergic synapse 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
227	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
228	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
229	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
230	Endocrine and other factor-regulated calcium reabsorption 💬	[1] VDR 💬	D00122 💬	Calcifediol	[2] 113, 299 💬
231	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
232	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
233	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
234	Endocrine resistance 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
235	Epithelial cell signaling in Helicobacter pylori infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
236	Epstein-Barr virus infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
237	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
238	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
239	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
240	Fc epsilon RI signaling pathway 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
241	Fc epsilon RI signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
242	Fluid shear stress and atherosclerosis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
243	Fluid shear stress and atherosclerosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
244	Fluid shear stress and atherosclerosis 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
245	Fluid shear stress and atherosclerosis 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
246	FoxO signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
247	FoxO signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
248	FoxO signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
249	Gap junction 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
250	Gap junction 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
251	Gap junction 💬	[1] ADRB1 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
252	Gap junction 💬	[1] ADRB1 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
253	Gap junction 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
254	Gap junction 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
255	Gap junction 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
256	Gap junction 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
257	Glucagon signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
258	Glucagon signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
259	Glucagon signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
260	Glucagon signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
261	Glucagon signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
262	Glutamatergic synapse 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
263	Glutamatergic synapse 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
264	Glutamatergic synapse 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
265	Glutamatergic synapse 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
266	Glutamatergic synapse 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
267	GnRH secretion 💬	[1] ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
268	GnRH secretion 💬	[1] ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
269	GnRH secretion 💬	[1] ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
270	GnRH signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
271	Graft-versus-host disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
272	Growth hormone synthesis, secretion and action 💬	[1] GHR 💬	D02691 💬	Somatotropin	[20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
273	Growth hormone synthesis, secretion and action 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
274	Hematopoietic cell lineage 💬	[1] CSF3R 💬	D03235 💬	Filgrastim	[33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
275	Hematopoietic cell lineage 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
276	Hepatitis B 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
277	Herpes simplex virus 1 infection 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
278	Hippo signaling pathway 💬	[1] CCN2 💬	D10969 💬	Pamrevlumab	[2] 85, 113 💬
279	Human cytomegalovirus infection 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
280	Human cytomegalovirus infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
281	Human cytomegalovirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
282	Human cytomegalovirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
283	Human cytomegalovirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
284	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
285	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
286	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
287	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
288	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
289	Human immunodeficiency virus 1 infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
290	Human immunodeficiency virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
291	Human immunodeficiency virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
292	Human immunodeficiency virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
293	Human papillomavirus infection 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
294	Human papillomavirus infection 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
295	Human papillomavirus infection 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
296	Human papillomavirus infection 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
297	Human papillomavirus infection 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
298	Human T-cell leukemia virus 1 infection 💬	[1] FDPS 💬	D00942 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
299	Human T-cell leukemia virus 1 infection 💬	[1] FDPS 💬	D03234 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
300	Human T-cell leukemia virus 1 infection 💬	[1] FDPS 💬	D08484 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
301	Human T-cell leukemia virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
302	Human T-cell leukemia virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
303	Human T-cell leukemia virus 1 infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
304	Huntington disease 💬	[2] GRIN1, GRIN2B 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
305	Huntington disease 💬	[2] GRIN1, GRIN2B 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
306	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00621 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
307	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D07892 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
308	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00362 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
309	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D08131 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
310	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00624 💬	Perindopril	[3] 113, 167, 222 💬
311	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D03753 💬	Perindopril	[3] 113, 167, 222 💬
312	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
313	Hypertrophic cardiomyopathy 💬	[1] DMD 💬	D11988 💬	Casimersen	[1] 113 💬
314	Hypertrophic cardiomyopathy 💬	[1] DMD 💬	D10114 💬	Drisapersen	[1] 113 💬
315	Hypertrophic cardiomyopathy 💬	[1] DMD 💬	D09900 💬	Eteplirsen	[1] 113 💬
316	Hypertrophic cardiomyopathy 💬	[1] DMD 💬	D11707 💬	Golodirsen	[1] 113 💬
317	Hypertrophic cardiomyopathy 💬	[1] DMD 💬	D11528 💬	Viltolarsen	[1] 113 💬
318	Hypertrophic cardiomyopathy 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
319	Hypertrophic cardiomyopathy 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
320	IL-17 signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
321	IL-17 signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
322	IL-17 signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
323	IL-17 signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
324	IL-17 signaling pathway 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
325	IL-17 signaling pathway 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
326	IL-17 signaling pathway 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
327	Inflammatory bowel disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
328	Inflammatory mediator regulation of TRP channels 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
329	Inflammatory mediator regulation of TRP channels 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
330	Influenza A 💬	[1] FDPS 💬	D00942 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
331	Influenza A 💬	[1] FDPS 💬	D03234 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
332	Influenza A 💬	[1] FDPS 💬	D08484 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
333	Influenza A 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
334	Insulin resistance 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
335	Insulin resistance 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
336	Insulin secretion 💬	[1] SNAP25 💬	D00783 💬	Botulinum toxin type A	[13] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
337	Insulin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
338	Insulin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
339	JAK-STAT signaling pathway 💬	[1] CSF3R 💬	D03235 💬	Filgrastim	[33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
340	JAK-STAT signaling pathway 💬	[1] GHR 💬	D02691 💬	Somatotropin	[20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
341	Kaposi sarcoma-associated herpesvirus infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
342	Kaposi sarcoma-associated herpesvirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
343	Kaposi sarcoma-associated herpesvirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
344	Kaposi sarcoma-associated herpesvirus infection 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
345	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
346	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
347	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
348	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
349	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
350	Legionellosis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
351	Leishmaniasis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
352	Leishmaniasis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
353	Leishmaniasis 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
354	Leishmaniasis 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
355	Leishmaniasis 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
356	Leishmaniasis 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
357	Leishmaniasis 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
358	Leukocyte transendothelial migration 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
359	Long-term potentiation 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
360	Long-term potentiation 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
361	Long-term potentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
362	Long-term potentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
363	Long-term potentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
364	Longevity regulating pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
365	Longevity regulating pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
366	Longevity regulating pathway - multiple species 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
367	Longevity regulating pathway - multiple species 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
368	Malaria 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
369	MAPK signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
370	MAPK signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
371	MAPK signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
372	MAPK signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
373	MAPK signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
374	Measles 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
375	Metabolic pathways 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
376	Metabolic pathways 💬	[1] FDPS 💬	D00942 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
377	Metabolic pathways 💬	[1] FDPS 💬	D03234 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
378	Metabolic pathways 💬	[1] FDPS 💬	D08484 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
379	Metabolic pathways 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
380	Metabolic pathways 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
381	Metabolic pathways 💬	[1] PDE5A 💬	D02008 💬	Tadalafil	[7] 6 , 51, 75, 84, 86, 113, 210 💬
382	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
383	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
384	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
385	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
386	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
387	MicroRNAs in cancer 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
388	MicroRNAs in cancer 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
389	MicroRNAs in cancer 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
390	MicroRNAs in cancer 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
391	MicroRNAs in cancer 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
392	Mineral absorption 💬	[1] VDR 💬	D00122 💬	Calcifediol	[2] 113, 299 💬
393	mTOR signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
394	mTOR signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
395	Natural killer cell mediated cytotoxicity 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
396	Natural killer cell mediated cytotoxicity 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
397	Natural killer cell mediated cytotoxicity 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
398	Necroptosis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
399	Neuroactive ligand-receptor interaction 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
400	Neuroactive ligand-receptor interaction 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
401	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬	D00514 💬	Dexmedetomidine	[12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
402	Neuroactive ligand-receptor interaction 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬	D01205 💬	Dexmedetomidine	[12] 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
403	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
404	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
405	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
406	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
407	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
408	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
409	Neuroactive ligand-receptor interaction 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
410	Neuroactive ligand-receptor interaction 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
411	Neuroactive ligand-receptor interaction 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
412	Neuroactive ligand-receptor interaction 💬	[1] GHR 💬	D02691 💬	Somatotropin	[20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
413	Neuroactive ligand-receptor interaction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
414	Neuroactive ligand-receptor interaction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
415	Neuroactive ligand-receptor interaction 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
416	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D03671 💬	Deflazacort	[2] 30, 113 💬
417	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00472 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
418	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00980 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
419	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00981 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
420	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00982 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
421	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D01239 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
422	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D01998 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
423	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D02156 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
424	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D03301 💬	Prednisolone	[40] 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
425	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00473 💬	Prednisone	[47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
426	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D11000 💬	Vamorolone	[2] 97, 113 💬
427	Neuroactive ligand-receptor interaction 💬	[1] TBXA2R 💬	D04500 💬	Ifetroban	[3] 51, 86, 113 💬
428	Neurotrophin signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
429	Neutrophil extracellular trap formation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
430	NF-kappa B signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
431	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
432	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
433	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
434	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
435	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
436	Nicotine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
437	Nicotine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
438	NOD-like receptor signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
439	NOD-like receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
440	Non-alcoholic fatty liver disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
441	Non-alcoholic fatty liver disease 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
442	Non-alcoholic fatty liver disease 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
443	Oocyte meiosis 💬	[1] AR 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
444	Oocyte meiosis 💬	[1] AR 💬	D00075 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
445	Oocyte meiosis 💬	[1] AR 💬	D00957 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
446	Oocyte meiosis 💬	[1] AR 💬	D00958 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
447	Oocyte meiosis 💬	[1] AR 💬	D00959 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
448	Oocyte meiosis 💬	[1] AR 💬	D06085 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
449	Oocyte meiosis 💬	[1] AR 💬	D06087 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
450	Oocyte meiosis 💬	[1] AR 💬	D08573 💬	Testosterone decanoate	[1] 113 💬
451	Oocyte meiosis 💬	[1] AR 💬	D00958 💬	Testosterone enanthate	[2] 13, 113 💬
452	Oocyte meiosis 💬	[1] AR 💬	D08574 💬	Testosterone phenylpropionate	[1] 113 💬
453	Oocyte meiosis 💬	[1] AR 💬	D00959 💬	Testosterone propionate	[1] 113 💬
454	Oocyte meiosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
455	Oocyte meiosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
456	Oocyte meiosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
457	Oocyte meiosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
458	Osteoclast differentiation 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
459	Osteoclast differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
460	Osteoclast differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
461	Osteoclast differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
462	Osteoclast differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
463	Ovarian steroidogenesis 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
464	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
465	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
466	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
467	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
468	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
469	Oxytocin signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
470	Oxytocin signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
471	Oxytocin signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
472	Oxytocin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
473	Oxytocin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
474	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
475	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
476	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
477	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
478	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
479	Parathyroid hormone synthesis, secretion and action 💬	[1] VDR 💬	D00122 💬	Calcifediol	[2] 113, 299 💬
480	Parkinson disease 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
481	Parkinson disease 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
482	Pathogenic Escherichia coli infection 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
483	Pathogenic Escherichia coli infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
484	Pathways in cancer 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
485	Pathways in cancer 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
486	Pathways in cancer 💬	[1] AR 💬	D00075 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
487	Pathways in cancer 💬	[1] AR 💬	D00957 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
488	Pathways in cancer 💬	[1] AR 💬	D00958 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
489	Pathways in cancer 💬	[1] AR 💬	D00959 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
490	Pathways in cancer 💬	[1] AR 💬	D06085 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
491	Pathways in cancer 💬	[1] AR 💬	D06087 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
492	Pathways in cancer 💬	[1] AR 💬	D08573 💬	Testosterone decanoate	[1] 113 💬
493	Pathways in cancer 💬	[1] AR 💬	D00958 💬	Testosterone enanthate	[2] 13, 113 💬
494	Pathways in cancer 💬	[1] AR 💬	D08574 💬	Testosterone phenylpropionate	[1] 113 💬
495	Pathways in cancer 💬	[1] AR 💬	D00959 💬	Testosterone propionate	[1] 113 💬
496	Pathways in cancer 💬	[3] AR, ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
497	Pathways in cancer 💬	[1] CSF3R 💬	D03235 💬	Filgrastim	[33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
498	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
499	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
500	Pathways in cancer 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
501	Pathways in cancer 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
502	Pathways in cancer 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
503	Pathways in cancer 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
504	Pathways in cancer 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
505	Pathways of neurodegeneration - multiple diseases 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
506	Pathways of neurodegeneration - multiple diseases 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
507	Pathways of neurodegeneration - multiple diseases 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
508	Pathways of neurodegeneration - multiple diseases 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
509	Pathways of neurodegeneration - multiple diseases 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
510	Pathways of neurodegeneration - multiple diseases 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
511	Pathways of neurodegeneration - multiple diseases 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
512	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
513	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
514	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
515	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
516	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
517	Pathways of neurodegeneration - multiple diseases 💬	[1] SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
518	Pathways of neurodegeneration - multiple diseases 💬	[1] SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
519	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
520	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
521	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
522	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
523	Pertussis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
524	Pertussis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
525	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
526	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
527	PI3K-Akt signaling pathway 💬	[1] CSF3R 💬	D03235 💬	Filgrastim	[33] 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
528	PI3K-Akt signaling pathway 💬	[1] GHR 💬	D02691 💬	Somatotropin	[20] 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
529	PI3K-Akt signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
530	PI3K-Akt signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
531	Platelet activation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
532	Platelet activation 💬	[1] PTGS1 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
533	Platelet activation 💬	[1] PTGS1 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
534	Platelet activation 💬	[1] PTGS1 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
535	Platelet activation 💬	[1] PTGS1 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
536	Platelet activation 💬	[1] PTGS1 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
537	Platelet activation 💬	[1] TBXA2R 💬	D04500 💬	Ifetroban	[3] 51, 86, 113 💬
538	Prion disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
539	Prion disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
540	Prion disease 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
541	Prion disease 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
542	Prion disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
543	Prion disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
544	Prion disease 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
545	Progesterone-mediated oocyte maturation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
546	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
547	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
548	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
549	Prolactin signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
550	Prostate cancer 💬	[1] AR 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
551	Prostate cancer 💬	[1] AR 💬	D00075 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
552	Prostate cancer 💬	[1] AR 💬	D00957 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
553	Prostate cancer 💬	[1] AR 💬	D00958 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
554	Prostate cancer 💬	[1] AR 💬	D00959 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
555	Prostate cancer 💬	[1] AR 💬	D06085 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
556	Prostate cancer 💬	[1] AR 💬	D06087 💬	Testosterone	[8] 1 , 2 , 3 , 13, 60, 78, 113, 265 💬
557	Prostate cancer 💬	[1] AR 💬	D08573 💬	Testosterone decanoate	[1] 113 💬
558	Prostate cancer 💬	[1] AR 💬	D00958 💬	Testosterone enanthate	[2] 13, 113 💬
559	Prostate cancer 💬	[1] AR 💬	D08574 💬	Testosterone phenylpropionate	[1] 113 💬
560	Prostate cancer 💬	[1] AR 💬	D00959 💬	Testosterone propionate	[1] 113 💬
561	Proteoglycans in cancer 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
562	Proteoglycans in cancer 💬	[1] ESR1 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
563	Proteoglycans in cancer 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
564	Proteoglycans in cancer 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
565	Purine metabolism 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
566	Purine metabolism 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
567	Purine metabolism 💬	[1] PDE5A 💬	D02008 💬	Tadalafil	[7] 6 , 51, 75, 84, 86, 113, 210 💬
568	Rap1 signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
569	Rap1 signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
570	Rap1 signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
571	Ras signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
572	Ras signaling pathway 💬	[3] GRIN1, GRIN2A, GRIN2B 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
573	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
574	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
575	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
576	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
577	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
578	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
579	Regulation of lipolysis in adipocytes 💬	[2] ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
580	Regulation of lipolysis in adipocytes 💬	[2] ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
581	Regulation of lipolysis in adipocytes 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
582	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
583	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
584	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
585	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
586	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
587	Relaxin signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
588	Renin secretion 💬	[1] ACE 💬	D00621 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
589	Renin secretion 💬	[1] ACE 💬	D07892 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
590	Renin secretion 💬	[1] ACE 💬	D00362 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
591	Renin secretion 💬	[1] ACE 💬	D08131 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
592	Renin secretion 💬	[1] ACE 💬	D00624 💬	Perindopril	[3] 113, 167, 222 💬
593	Renin secretion 💬	[1] ACE 💬	D03753 💬	Perindopril	[3] 113, 167, 222 💬
594	Renin secretion 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
595	Renin secretion 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
596	Renin secretion 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
597	Renin secretion 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
598	Renin secretion 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
599	Renin secretion 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
600	Renin secretion 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
601	Renin secretion 💬	[2] ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
602	Renin secretion 💬	[2] ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
603	Renin secretion 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
604	Renin secretion 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
605	Renin secretion 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
606	Renin secretion 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
607	Renin secretion 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
608	Renin secretion 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
609	Renin-angiotensin system 💬	[1] ACE 💬	D00621 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
610	Renin-angiotensin system 💬	[1] ACE 💬	D07892 💬	Enalapril	[7] 19, 46, 66, 113, 210, 222, 223 💬
611	Renin-angiotensin system 💬	[1] ACE 💬	D00362 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
612	Renin-angiotensin system 💬	[1] ACE 💬	D08131 💬	Lisinopril	[7] 19, 46, 49, 66, 67, 113, 222 💬
613	Renin-angiotensin system 💬	[1] ACE 💬	D00624 💬	Perindopril	[3] 113, 167, 222 💬
614	Renin-angiotensin system 💬	[1] ACE 💬	D03753 💬	Perindopril	[3] 113, 167, 222 💬
615	Renin-angiotensin system 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
616	Renin-angiotensin system 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
617	Renin-angiotensin system 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
618	Retrograde endocannabinoid signaling 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
619	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
620	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
621	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
622	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
623	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
624	Rheumatoid arthritis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
625	RIG-I-like receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
626	Salivary secretion 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
627	Salivary secretion 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
628	Salivary secretion 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
629	Salivary secretion 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
630	Salivary secretion 💬	[1] ADRB1 💬	D00601 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
631	Salivary secretion 💬	[1] ADRB1 💬	D02358 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
632	Salivary secretion 💬	[1] ADRB1 💬	D05011 💬	Metoprolol	[6] 17, 57, 58, 113, 193, 226 💬
633	Salivary secretion 💬	[1] ADRB1 💬	D05127 💬	Nebivolol	[3] 17, 113, 167 💬
634	Salivary secretion 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
635	Salmonella infection 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
636	Salmonella infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
637	Serotonergic synapse 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
638	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
639	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
640	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
641	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
642	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
643	Shigellosis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
644	Shigellosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
645	Signaling pathways regulating pluripotency of stem cells 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
646	Small cell lung cancer 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
647	Small cell lung cancer 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
648	Small cell lung cancer 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
649	Small cell lung cancer 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
650	Small cell lung cancer 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
651	Sphingolipid signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
652	Spinocerebellar ataxia 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
653	Spinocerebellar ataxia 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
654	Synaptic vesicle cycle 💬	[2] SLC6A2, SLC6A3 💬	D01296 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
655	Synaptic vesicle cycle 💬	[2] SLC6A2, SLC6A3 💬	D04999 💬	Methylphenidate	[7] 6 , 13, 34, 84, 113, 179, 206 💬
656	Synaptic vesicle cycle 💬	[1] SNAP25 💬	D00783 💬	Botulinum toxin type A	[13] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
657	Systemic lupus erythematosus 💬	[2] GRIN2A, GRIN2B 💬	D00711 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
658	Systemic lupus erythematosus 💬	[2] GRIN2A, GRIN2B 💬	D08098 💬	Ketamine	[8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬
659	T cell receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
660	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
661	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
662	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
663	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00639 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
664	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08215 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
665	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D00942 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
666	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D03234 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
667	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D08484 💬	Risedronic acid	[8] 46, 50, 66, 93, 95, 96, 113, 274 💬
668	Terpenoid backbone biosynthesis 💬	[2] FNTA, FNTB 💬	D04768 💬	Lonafarnib	[2] 113, 333 💬
669	Th1 and Th2 cell differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
670	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
671	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
672	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
673	Th17 cell differentiation 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
674	Th17 cell differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
675	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
676	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
677	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
678	Thermogenesis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
679	Thermogenesis 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
680	Thermogenesis 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
681	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
682	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
683	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
684	Tight junction 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
685	Tight junction 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
686	TNF signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
687	TNF signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
688	TNF signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
689	TNF signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
690	TNF signaling pathway 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
691	TNF signaling pathway 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
692	TNF signaling pathway 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
693	Toll-like receptor signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
694	Toll-like receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
695	Toxoplasmosis 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
696	Toxoplasmosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
697	Tuberculosis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
698	Tuberculosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
699	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
700	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
701	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
702	Tuberculosis 💬	[1] VDR 💬	D00122 💬	Calcifediol	[2] 113, 299 💬
703	Type I diabetes mellitus 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
704	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
705	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
706	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D00357 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
707	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D08146 💬	Losartan	[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
708	VEGF signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
709	VEGF signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
710	VEGF signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
711	VEGF signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
712	VEGF signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
713	VEGF signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
714	VEGF signaling pathway 💬	[1] PTGS2 💬	D01122 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
715	VEGF signaling pathway 💬	[1] PTGS2 💬	D04490 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
716	VEGF signaling pathway 💬	[1] PTGS2 💬	D06606 💬	Ibuprofen	[6] 13, 46, 65, 113, 271, 299 💬
717	Viral myocarditis 💬	[1] DMD 💬	D11988 💬	Casimersen	[1] 113 💬
718	Viral myocarditis 💬	[1] DMD 💬	D10114 💬	Drisapersen	[1] 113 💬
719	Viral myocarditis 💬	[1] DMD 💬	D09900 💬	Eteplirsen	[1] 113 💬
720	Viral myocarditis 💬	[1] DMD 💬	D11707 💬	Golodirsen	[1] 113 💬
721	Viral myocarditis 💬	[1] DMD 💬	D11528 💬	Viltolarsen	[1] 113 💬
722	Wnt signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
723	Wnt signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
724	Wnt signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[32] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 299 💬
725	Yersinia infection 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
726	Yersinia infection 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬