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Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

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66 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
3 Adrenergic signaling in cardiomyocytes 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
4 Aldosterone synthesis and secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
5 Aldosterone-regulated sodium reabsorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
6 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 D01115 💬 Eplerenone [4] 75, 113, 210, 215 💬
7 Aldosterone-regulated sodium reabsorption 💬
 [1] NR3C2 💬 D00443 💬 Spironolactone [7] 58, 67, 86, 113, 210, 218, 225 💬
8 Alzheimer disease 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
9 Alzheimer disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
10 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
11 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
12 Amyotrophic lateral sclerosis 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
13 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
14 Bile secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
15 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
16 Calcium signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
17 Calcium signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
18 Calcium signaling pathway 💬
 [2] AVPR1A, AVPR1B 💬 D00101 💬 Vasopressin [1] 210 💬
19 Calcium signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
20 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
21 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
22 Calcium signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
23 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
24 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
25 cAMP signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
26 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
27 cAMP signaling pathway 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
28 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
29 cAMP signaling pathway 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
30 Carbohydrate digestion and absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
31 Cardiac muscle contraction 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
32 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
33 cGMP-PKG signaling pathway 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
34 cGMP-PKG signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
35 cGMP-PKG signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
36 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
37 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
38 cGMP-PKG signaling pathway 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
39 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
40 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
41 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
42 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
43 Chagas disease 💬
 [1] ACE 💬 D00621 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
44 Chagas disease 💬
 [1] ACE 💬 D07892 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
45 Chemical carcinogenesis 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
46 Complement and coagulation cascades 💬
 [1] F10 💬 D07086 💬 Rivaroxaban [5] 46, 49, 75, 91, 210 💬
47 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 D00621 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
48 Coronavirus disease - COVID-19 💬
 [1] ACE 💬 D07892 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
49 Diabetic cardiomyopathy 💬
 [1] ACE 💬 D00621 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
50 Diabetic cardiomyopathy 💬
 [1] ACE 💬 D07892 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
51 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
52 Dilated cardiomyopathy 💬
 [1] ADRB1 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
53 Endocrine and other factor-regulated calcium reabsorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
54 Gap junction 💬
 [1] ADRB1 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
55 Gap junction 💬
 [1] ADRB1 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
56 Gap junction 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
57 Gastric acid secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
58 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
59 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
60 Huntington disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
61 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 D00621 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
62 Hypertrophic cardiomyopathy 💬
 [1] ACE 💬 D07892 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
63 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
64 Insulin secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
65 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
66 Leishmaniasis 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
67 Melanogenesis 💬
 [1] EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
68 Melanogenesis 💬
 [1] EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
69 Melanogenesis 💬
 [1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
70 Metabolic pathways 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
71 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
72 Metabolic pathways 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
73 Metabolic pathways 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
74 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
75 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
76 Mineral absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
77 Neuroactive ligand-receptor interaction 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
78 Neuroactive ligand-receptor interaction 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
79 Neuroactive ligand-receptor interaction 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 D00101 💬 Vasopressin [1] 210 💬
80 Neuroactive ligand-receptor interaction 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
81 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
82 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
83 Neuroactive ligand-receptor interaction 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
84 Neuroactive ligand-receptor interaction 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
85 Neuroactive ligand-receptor interaction 💬
 [2] THRA, THRB 💬 D01011 💬 Liothyronine [4] 13, 78, 210, 212 💬
86 Neuroactive ligand-receptor interaction 💬
 [2] THRA, THRB 💬 D08128 💬 Liothyronine [4] 13, 78, 210, 212 💬
87 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
88 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
89 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
90 Pancreatic secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
91 Parkinson disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
92 Pathogenic Escherichia coli infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
93 Pathways in cancer 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
94 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
95 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
96 Pathways in cancer 💬
 [2] EDNRA, EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
97 Pathways in cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
98 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
99 Pathways of neurodegeneration - multiple diseases 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
100 Phagosome 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
101 Phospholipase D signaling pathway 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 D00101 💬 Vasopressin [1] 210 💬
102 Platelet activation 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
103 Platelet activation 💬
 [1] PTGS1 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
104 Prion disease 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
105 Protein digestion and absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
106 Proximal tubule bicarbonate reclamation 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
107 Purine metabolism 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
108 Purine metabolism 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
109 Purine metabolism 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
110 Purine metabolism 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
111 Regulation of lipolysis in adipocytes 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
112 Regulation of lipolysis in adipocytes 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
113 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
114 Relaxin signaling pathway 💬
 [1] EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
115 Relaxin signaling pathway 💬
 [1] EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
116 Relaxin signaling pathway 💬
 [1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
117 Renin secretion 💬
 [1] ACE 💬 D00621 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
118 Renin secretion 💬
 [1] ACE 💬 D07892 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
119 Renin secretion 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
120 Renin secretion 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
121 Renin secretion 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
122 Renin secretion 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
123 Renin secretion 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
124 Renin secretion 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
125 Renin-angiotensin system 💬
 [1] ACE 💬 D00621 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
126 Renin-angiotensin system 💬
 [1] ACE 💬 D07892 💬 Enalapril [7] 19, 46, 66, 113, 210, 222, 223 💬
127 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
128 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
129 Salivary secretion 💬
 [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
130 Salivary secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
131 Salmonella infection 💬
 [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine [7]  2 , 42, 46, 56, 93, 210, 266 💬
132 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
133 Small cell lung cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
134 Thyroid hormone signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
135 Thyroid hormone signaling pathway 💬
 [2] THRA, THRB 💬 D01011 💬 Liothyronine [4] 13, 78, 210, 212 💬
136 Thyroid hormone signaling pathway 💬
 [2] THRA, THRB 💬 D08128 💬 Liothyronine [4] 13, 78, 210, 212 💬
137 Thyroid hormone synthesis 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
138 TNF signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
139 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
140 Vascular smooth muscle contraction 💬
 [3] ADRA1A, ADRA1B, ADRA1D 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
141 Vascular smooth muscle contraction 💬
 [2] AVPR1A, AVPR1B 💬 D00101 💬 Vasopressin [1] 210 💬
142 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
143 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
144 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
145 Vascular smooth muscle contraction 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
146 Vascular smooth muscle contraction 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
147 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 D00101 💬 Vasopressin [1] 210 💬
148 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬

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