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Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

ABCDEFGH I JKLMNOPQRSTUVWXYZother

14 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Apelin signaling pathway 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
2 Apelin signaling pathway 💬
 [1] PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
3 cAMP signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
4 cAMP signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
5 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
6 cGMP-PKG signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
7 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
8 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
9 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
10 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
11 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
12 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
13 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
14 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
15 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
16 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
17 Glucagon signaling pathway 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
18 Glucagon signaling pathway 💬
 [1] PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
19 Insulin signaling pathway 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
20 Insulin signaling pathway 💬
 [1] PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
21 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
22 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
23 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
24 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
25 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
26 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
27 Metabolic pathways 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
28 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
29 Morphine addiction 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
30 Morphine addiction 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
31 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
32 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D01207 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
33 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D05259 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
34 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 D05261 💬 Omeprazole [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
35 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
36 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
37 Purine metabolism 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
38 Purine metabolism 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
39 Purine metabolism 💬
 [1] PDE5A 💬 D02229 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
40 Purine metabolism 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
41 Regulation of lipolysis in adipocytes 💬
 [1] PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
42 Regulation of lipolysis in adipocytes 💬
 [1] PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
43 Renin secretion 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
44 Renin secretion 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬

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