DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway💬 Info on mouse-over

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185 / 286 pathways

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[4] BRAF, FLT3, KIT, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
2	Acute myeloid leukemia 💬	[4] BRAF, FLT3, KIT, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
3	Acute myeloid leukemia 💬	[1] KIT 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
4	Acute myeloid leukemia 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5	Acute myeloid leukemia 💬	[1] KIT 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
6	Acute myeloid leukemia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
7	Adherens junction 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
8	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
9	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
10	Adipocytokine signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
11	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
12	Adrenergic signaling in cardiomyocytes 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
13	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
14	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
15	Adrenergic signaling in cardiomyocytes 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
16	Adrenergic signaling in cardiomyocytes 💬	[2] AGTR1, AGTR2 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
17	Adrenergic signaling in cardiomyocytes 💬	[2] AGTR1, AGTR2 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
18	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
19	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
20	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
21	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
22	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
23	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D00358 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
24	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D02086 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
25	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D08127 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
26	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
27	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
28	AGE-RAGE signaling pathway in diabetic complications 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
29	Alcoholism 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
30	Alcoholism 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
31	Alcoholism 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
32	Alcoholism 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
33	Alcoholism 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
34	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
35	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
36	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
37	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
38	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
39	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
40	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
41	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
42	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
43	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D00443 💬	Spironolactone	[7] 58, 67, 86, 113, 210, 218, 225 💬
44	Alzheimer disease 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
45	Alzheimer disease 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
46	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
47	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
48	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
49	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
50	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
51	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
52	Alzheimer disease 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
53	Alzheimer disease 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
54	Alzheimer disease 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
55	Alzheimer disease 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
56	Amoebiasis 💬	[2] IL1R1, IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
57	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
58	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
59	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
60	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
61	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
62	AMPK signaling pathway 💬	[1] ADRA1A 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
63	AMPK signaling pathway 💬	[1] ADRA1A 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
64	AMPK signaling pathway 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
65	AMPK signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
66	AMPK signaling pathway 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
67	AMPK signaling pathway 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
68	AMPK signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
69	AMPK signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
70	Amyotrophic lateral sclerosis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
71	Amyotrophic lateral sclerosis 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
72	Apelin signaling pathway 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
73	Apelin signaling pathway 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
74	Apelin signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
75	Apelin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
76	Apelin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
77	Apelin signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
78	Apelin signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
79	Apoptosis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
80	Apoptosis 💬	[2] PARP1, PARP2 💬	D09730 💬	Olaparib	[2] 86, 285 💬
81	Apoptosis 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
82	Apoptosis 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
83	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
84	Arachidonic acid metabolism 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
85	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
86	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
87	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
88	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
89	Arrhythmogenic right ventricular cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
90	Autophagy - animal 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
91	Autophagy - animal 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
92	Autophagy - animal 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
93	Autophagy - animal 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
94	Autophagy - animal 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
95	Autophagy - other 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
96	Axon guidance 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
97	Axon guidance 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
98	Axon guidance 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
99	Axon guidance 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
100	Axon guidance 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
101	B cell receptor signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
102	B cell receptor signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
103	Base excision repair 💬	[2] PARP1, PARP2 💬	D09730 💬	Olaparib	[2] 86, 285 💬
104	Bile secretion 💬	[1] CA2 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
105	Bile secretion 💬	[1] CA2 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
106	Bile secretion 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
107	Bladder cancer 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
108	Bladder cancer 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
109	Bladder cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
110	Bladder cancer 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
111	Breast cancer 💬	[4] BRAF, FLT4, KIT, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
112	Breast cancer 💬	[4] BRAF, FLT4, KIT, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
113	Breast cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
114	Breast cancer 💬	[2] ESR1, ESR2 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
115	Breast cancer 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
116	Breast cancer 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
117	Breast cancer 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
118	Breast cancer 💬	[1] KIT 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
119	Breast cancer 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
120	Breast cancer 💬	[1] KIT 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
121	Breast cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
122	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
123	C-type lectin receptor signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
124	C-type lectin receptor signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
125	C-type lectin receptor signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
126	Calcium signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
127	Calcium signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
128	Calcium signaling pathway 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
129	Calcium signaling pathway 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
130	Calcium signaling pathway 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
131	Calcium signaling pathway 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
132	Calcium signaling pathway 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
133	Calcium signaling pathway 💬	[1] AVPR1A 💬	D01236 💬	Conivaptan	[1] 86 💬
134	Calcium signaling pathway 💬	[1] AVPR1A 💬	D07748 💬	Conivaptan	[1] 86 💬
135	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
136	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
137	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
138	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
139	Calcium signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
140	Calcium signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
141	Calcium signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
142	Calcium signaling pathway 💬	[4] CHRM1, CHRM2, CHRM3, CHRM5 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
143	Calcium signaling pathway 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
144	Calcium signaling pathway 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
145	Calcium signaling pathway 💬	[2] EDNRA, EDNRB 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
146	Calcium signaling pathway 💬	[2] EDNRA, EDNRB 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
147	Calcium signaling pathway 💬	[2] EDNRA, EDNRB 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
148	Calcium signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
149	Calcium signaling pathway 💬	[4] FLT4, KDR, PDGFRB, RET 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
150	Calcium signaling pathway 💬	[4] FLT4, KDR, PDGFRB, RET 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
151	Calcium signaling pathway 💬	[1] HRH1 💬	D00300 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
152	Calcium signaling pathway 💬	[1] HRH1 💬	D00669 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
153	Calcium signaling pathway 💬	[1] HRH1 💬	D02419 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
154	Calcium signaling pathway 💬	[1] HRH1 💬	D03285 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
155	Calcium signaling pathway 💬	[1] HRH1 💬	D03360 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
156	Calcium signaling pathway 💬	[1] HRH1 💬	D03854 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
157	Calcium signaling pathway 💬	[1] HRH2 💬	D00318 💬	Famotidine	[4] 6 , 46, 86, 98 💬
158	Calcium signaling pathway 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
159	Calcium signaling pathway 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
160	Calcium signaling pathway 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
161	Calcium signaling pathway 💬	[1] TBXA2R 💬	D04500 💬	Ifetroban	[3] 51, 86, 113 💬
162	Calcium signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
163	cAMP signaling pathway 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
164	cAMP signaling pathway 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
165	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
166	cAMP signaling pathway 💬	[2] ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
167	cAMP signaling pathway 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
168	cAMP signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
169	cAMP signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
170	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
171	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
172	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
173	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
174	cAMP signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
175	cAMP signaling pathway 💬	[2] CHRM1, CHRM2 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
176	cAMP signaling pathway 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
177	cAMP signaling pathway 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
178	cAMP signaling pathway 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
179	cAMP signaling pathway 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
180	cAMP signaling pathway 💬	[1] EDNRA 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
181	cAMP signaling pathway 💬	[1] EDNRA 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
182	cAMP signaling pathway 💬	[1] EDNRA 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
183	cAMP signaling pathway 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
184	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
185	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
186	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
187	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
188	Carbohydrate digestion and absorption 💬	[1] CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
189	Carbohydrate digestion and absorption 💬	[2] TAS1R2, TAS1R3 💬	D02381 💬	Aspartame	[5] 6 , 13, 67, 86, 230 💬
190	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
191	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
192	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
193	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
194	Cardiac muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
195	Cell cycle 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
196	Cell cycle 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
197	Cell cycle 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
198	Cellular senescence 💬	[1] CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
199	Cellular senescence 💬	[1] CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
200	Cellular senescence 💬	[1] CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
201	Cellular senescence 💬	[1] CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
202	Cellular senescence 💬	[1] CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
203	Cellular senescence 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
204	Cellular senescence 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
205	Cellular senescence 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
206	Central carbon metabolism in cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
207	Central carbon metabolism in cancer 💬	[5] FLT3, KIT, PDGFRB, RAF1, RET 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
208	Central carbon metabolism in cancer 💬	[5] FLT3, KIT, PDGFRB, RAF1, RET 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
209	Central carbon metabolism in cancer 💬	[2] KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
210	Central carbon metabolism in cancer 💬	[2] KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
211	Central carbon metabolism in cancer 💬	[3] KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
212	Central carbon metabolism in cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
213	cGMP-PKG signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
214	cGMP-PKG signaling pathway 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
215	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
216	cGMP-PKG signaling pathway 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
217	cGMP-PKG signaling pathway 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
218	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
219	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
220	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
221	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
222	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
223	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
224	cGMP-PKG signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
225	cGMP-PKG signaling pathway 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
226	cGMP-PKG signaling pathway 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
227	cGMP-PKG signaling pathway 💬	[2] EDNRA, EDNRB 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
228	cGMP-PKG signaling pathway 💬	[2] EDNRA, EDNRB 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
229	cGMP-PKG signaling pathway 💬	[2] EDNRA, EDNRB 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
230	cGMP-PKG signaling pathway 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
231	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
232	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
233	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D02008 💬	Tadalafil	[7] 6 , 51, 75, 84, 86, 113, 210 💬
234	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D10027 💬	Udenafil	[2] 86, 210 💬
235	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D02731 💬	Vardenafil	[3] 13, 86, 299 💬
236	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D03260 💬	Vardenafil	[3] 13, 86, 299 💬
237	cGMP-PKG signaling pathway 💬	[1] PDE5A 💬	D08668 💬	Vardenafil	[3] 13, 86, 299 💬
238	cGMP-PKG signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
239	cGMP-PKG signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
240	Chagas disease 💬	[1] ACE 💬	D00251 💬	Captopril	[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬
241	Chemical carcinogenesis 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
242	Chemical carcinogenesis 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
243	Chemokine signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
244	Chemokine signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
245	Choline metabolism in cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
246	Choline metabolism in cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
247	Choline metabolism in cancer 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
248	Choline metabolism in cancer 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
249	Choline metabolism in cancer 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
250	Choline metabolism in cancer 💬	[2] PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
251	Choline metabolism in cancer 💬	[2] PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
252	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
253	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
254	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
255	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
256	Cholinergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
257	Cholinergic synapse 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
258	Chronic myeloid leukemia 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
259	Chronic myeloid leukemia 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
260	Chronic myeloid leukemia 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
261	Chronic myeloid leukemia 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
262	Chronic myeloid leukemia 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
263	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
264	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
265	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
266	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
267	Circadian entrainment 💬	[2] CACNA1C, CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
268	Circadian entrainment 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
269	Circadian entrainment 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
270	Circadian entrainment 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
271	Circadian rhythm 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
272	Circadian rhythm 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
273	Cocaine addiction 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
274	Cocaine addiction 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
275	Cocaine addiction 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
276	Collecting duct acid secretion 💬	[2] ATP4A, ATP4B 💬	D01984 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
277	Collecting duct acid secretion 💬	[2] ATP4A, ATP4B 💬	D04056 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
278	Collecting duct acid secretion 💬	[2] ATP4A, ATP4B 💬	D07917 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
279	Collecting duct acid secretion 💬	[2] ATP4A, ATP4B 💬	D09339 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
280	Collecting duct acid secretion 💬	[1] CA2 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
281	Collecting duct acid secretion 💬	[1] CA2 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
282	Colorectal cancer 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
283	Colorectal cancer 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
284	Colorectal cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
285	Colorectal cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
286	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00251 💬	Captopril	[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬
287	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
288	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
289	Coronavirus disease - COVID-19 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
290	Coronavirus disease - COVID-19 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
291	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
292	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
293	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
294	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
295	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
296	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
297	Cortisol synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
298	Cortisol synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
299	Cortisol synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
300	Cushing syndrome 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
301	Cushing syndrome 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
302	Cushing syndrome 💬	[1] BRAF 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
303	Cushing syndrome 💬	[1] BRAF 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
304	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
305	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
306	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
307	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
308	Cushing syndrome 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
309	Cushing syndrome 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
310	Cushing syndrome 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
311	Cushing syndrome 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
312	Cytokine-cytokine receptor interaction 💬	[1] ACVR2A 💬	D09670 💬	Sotatercept	[2] 86, 284 💬
313	Cytokine-cytokine receptor interaction 💬	[2] IL1R1, IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
314	Cytokine-cytokine receptor interaction 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
315	Cytokine-cytokine receptor interaction 💬	[1] PRL 💬	D01348 💬	Terguride	[2] 51, 86 💬
316	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00251 💬	Captopril	[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬
317	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
318	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
319	Diabetic cardiomyopathy 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
320	Diabetic cardiomyopathy 💬	[1] PARP1 💬	D09730 💬	Olaparib	[2] 86, 285 💬
321	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
322	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
323	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
324	Dilated cardiomyopathy 💬	[1] ADRB1 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
325	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
326	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
327	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
328	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
329	Dilated cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
330	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
331	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
332	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
333	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
334	Dopaminergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
335	Dopaminergic synapse 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
336	Dopaminergic synapse 💬	[3] DRD2, DRD3, DRD4 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
337	Dopaminergic synapse 💬	[3] DRD2, DRD3, DRD4 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
338	Dopaminergic synapse 💬	[1] SCN1A 💬	D00358 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
339	Dopaminergic synapse 💬	[1] SCN1A 💬	D02086 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
340	Dopaminergic synapse 💬	[1] SCN1A 💬	D08127 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
341	Drug metabolism - other enzymes 💬	[1] RRM2 💬	D00341 💬	Hydroxyurea	[8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
342	EGFR tyrosine kinase inhibitor resistance 💬	[4] BRAF, KDR, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
343	EGFR tyrosine kinase inhibitor resistance 💬	[4] BRAF, KDR, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
344	EGFR tyrosine kinase inhibitor resistance 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
345	EGFR tyrosine kinase inhibitor resistance 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
346	EGFR tyrosine kinase inhibitor resistance 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
347	EGFR tyrosine kinase inhibitor resistance 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
348	EGFR tyrosine kinase inhibitor resistance 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
349	EGFR tyrosine kinase inhibitor resistance 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
350	EGFR tyrosine kinase inhibitor resistance 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
351	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
352	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
353	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
354	Endocrine and other factor-regulated calcium reabsorption 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
355	Endocrine resistance 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
356	Endocrine resistance 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
357	Endocrine resistance 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
358	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
359	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
360	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
361	Endocrine resistance 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
362	Endocrine resistance 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
363	Endocytosis 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
364	Endocytosis 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
365	Endocytosis 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
366	Endocytosis 💬	[1] PDGFRA 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
367	Endometrial cancer 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
368	Endometrial cancer 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
369	Endometrial cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
370	Epithelial cell signaling in Helicobacter pylori infection 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
371	ErbB signaling pathway 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
372	ErbB signaling pathway 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
373	ErbB signaling pathway 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
374	ErbB signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
375	ErbB signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
376	ErbB signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
377	ErbB signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
378	Estrogen signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
379	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
380	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
381	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
382	Estrogen signaling pathway 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
383	Estrogen signaling pathway 💬	[1] OPRM1 💬	D00842 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
384	Estrogen signaling pathway 💬	[1] OPRM1 💬	D02271 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
385	Estrogen signaling pathway 💬	[1] OPRM1 💬	D08233 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
386	Estrogen signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
387	Estrogen signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
388	Fc epsilon RI signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
389	Fc epsilon RI signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
390	Fc gamma R-mediated phagocytosis 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
391	Fc gamma R-mediated phagocytosis 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
392	Fluid shear stress and atherosclerosis 💬	[1] ACVR2A 💬	D09670 💬	Sotatercept	[2] 86, 284 💬
393	Fluid shear stress and atherosclerosis 💬	[2] IL1R1, IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
394	Fluid shear stress and atherosclerosis 💬	[1] KDR 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
395	Fluid shear stress and atherosclerosis 💬	[1] KDR 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
396	Fluid shear stress and atherosclerosis 💬	[1] KEAP1 💬	D03846 💬	Dimethyl fumarate	[4] 13, 51, 86, 296 💬
397	Fluid shear stress and atherosclerosis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
398	Fluid shear stress and atherosclerosis 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
399	Fluid shear stress and atherosclerosis 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
400	Fluid shear stress and atherosclerosis 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
401	Focal adhesion 💬	[5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
402	Focal adhesion 💬	[5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
403	Focal adhesion 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
404	Focal adhesion 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
405	Focal adhesion 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
406	Focal adhesion 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
407	Focal adhesion 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
408	FoxO signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
409	FoxO signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
410	FoxO signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
411	FoxO signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
412	FoxO signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
413	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
414	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
415	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
416	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
417	GABAergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
418	Gap junction 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
419	Gap junction 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
420	Gap junction 💬	[1] ADRB1 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
421	Gap junction 💬	[1] ADRB1 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
422	Gap junction 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
423	Gap junction 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
424	Gap junction 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
425	Gap junction 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
426	Gap junction 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
427	Gap junction 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
428	Gap junction 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
429	Gap junction 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
430	Gap junction 💬	[2] PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
431	Gap junction 💬	[2] PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
432	Gastric acid secretion 💬	[2] ATP4A, ATP4B 💬	D01984 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
433	Gastric acid secretion 💬	[2] ATP4A, ATP4B 💬	D04056 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
434	Gastric acid secretion 💬	[2] ATP4A, ATP4B 💬	D07917 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
435	Gastric acid secretion 💬	[2] ATP4A, ATP4B 💬	D09339 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
436	Gastric acid secretion 💬	[1] CA2 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
437	Gastric acid secretion 💬	[1] CA2 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
438	Gastric acid secretion 💬	[1] CHRM3 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
439	Gastric acid secretion 💬	[1] HRH2 💬	D00318 💬	Famotidine	[4] 6 , 46, 86, 98 💬
440	Gastric cancer 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
441	Gastric cancer 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
442	Gastric cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
443	Gastric cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
444	Glioma 💬	[3] BRAF, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
445	Glioma 💬	[3] BRAF, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
446	Glioma 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
447	Glioma 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
448	Glioma 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
449	Glioma 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
450	Glioma 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
451	Glucagon signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
452	Glucagon signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
453	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
454	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
455	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
456	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
457	Glutamatergic synapse 💬	[2] CACNA1C, CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
458	Glutathione metabolism 💬	[1] ANPEP 💬	D00087 💬	Ubenimex	[1] 86 💬
459	Glutathione metabolism 💬	[1] RRM2 💬	D00341 💬	Hydroxyurea	[8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
460	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
461	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
462	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
463	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
464	GnRH secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
465	GnRH secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
466	GnRH secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
467	GnRH secretion 💬	[1] ESR2 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
468	GnRH secretion 💬	[1] ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
469	GnRH secretion 💬	[1] ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
470	GnRH secretion 💬	[1] ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
471	GnRH secretion 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
472	GnRH secretion 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
473	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
474	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
475	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
476	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
477	GnRH signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
478	GnRH signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
479	GnRH signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
480	GnRH signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
481	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
482	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
483	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
484	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
485	Growth hormone synthesis, secretion and action 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
486	Growth hormone synthesis, secretion and action 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
487	Growth hormone synthesis, secretion and action 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
488	Growth hormone synthesis, secretion and action 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
489	Hematopoietic cell lineage 💬	[1] ANPEP 💬	D00087 💬	Ubenimex	[1] 86 💬
490	Hematopoietic cell lineage 💬	[2] FLT3, KIT 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
491	Hematopoietic cell lineage 💬	[2] FLT3, KIT 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
492	Hematopoietic cell lineage 💬	[2] IL1R1, IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
493	Hematopoietic cell lineage 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
494	Hematopoietic cell lineage 💬	[1] KIT 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
495	Hematopoietic cell lineage 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
496	Hematopoietic cell lineage 💬	[1] KIT 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
497	Hematopoietic cell lineage 💬	[1] MS4A1 💬	D02994 💬	Rituximab	[47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
498	Hepatitis B 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
499	Hepatitis B 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
500	Hepatitis C 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
501	Hepatitis C 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
502	Hepatitis C 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
503	Hepatocellular carcinoma 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
504	Hepatocellular carcinoma 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
505	Hepatocellular carcinoma 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
506	Hepatocellular carcinoma 💬	[1] KEAP1 💬	D03846 💬	Dimethyl fumarate	[4] 13, 51, 86, 296 💬
507	Hepatocellular carcinoma 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
508	Herpes simplex virus 1 infection 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
509	HIF-1 signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
510	HIF-1 signaling pathway 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
511	HIF-1 signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
512	HIF-1 signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
513	Human cytomegalovirus infection 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
514	Human cytomegalovirus infection 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
515	Human cytomegalovirus infection 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
516	Human cytomegalovirus infection 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
517	Human cytomegalovirus infection 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
518	Human cytomegalovirus infection 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
519	Human cytomegalovirus infection 💬	[1] PDGFRA 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
520	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
521	Human cytomegalovirus infection 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
522	Human cytomegalovirus infection 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
523	Human cytomegalovirus infection 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
524	Human cytomegalovirus infection 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
525	Human immunodeficiency virus 1 infection 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
526	Human immunodeficiency virus 1 infection 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
527	Human immunodeficiency virus 1 infection 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
528	Human papillomavirus infection 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
529	Human papillomavirus infection 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
530	Human papillomavirus infection 💬	[1] PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
531	Human papillomavirus infection 💬	[2] PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
532	Human papillomavirus infection 💬	[2] PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
533	Human papillomavirus infection 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
534	Human papillomavirus infection 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
535	Human papillomavirus infection 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
536	Human T-cell leukemia virus 1 infection 💬	[2] IL1R1, IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
537	Huntington disease 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
538	Huntington disease 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
539	Huntington disease 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
540	Huntington disease 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
541	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00251 💬	Captopril	[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬
542	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
543	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
544	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
545	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
546	Hypertrophic cardiomyopathy 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
547	Hypertrophic cardiomyopathy 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
548	Hypertrophic cardiomyopathy 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
549	IL-17 signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
550	IL-17 signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
551	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬	D00300 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
552	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬	D00669 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
553	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬	D02419 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
554	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬	D03285 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
555	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬	D03360 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
556	Inflammatory mediator regulation of TRP channels 💬	[1] HRH1 💬	D03854 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
557	Inflammatory mediator regulation of TRP channels 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
558	Inflammatory mediator regulation of TRP channels 💬	[1] TRPV1 💬	D00250 💬	Capsaicin	[5] 2 , 6 , 19, 86, 226 💬
559	Influenza A 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
560	Influenza A 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
561	Insulin resistance 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
562	Insulin resistance 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
563	Insulin resistance 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
564	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
565	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
566	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
567	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
568	Insulin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
569	Insulin secretion 💬	[1] CHRM3 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
570	Insulin signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
571	Insulin signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
572	Insulin signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
573	Insulin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
574	Insulin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
575	JAK-STAT signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
576	JAK-STAT signaling pathway 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
577	JAK-STAT signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
578	JAK-STAT signaling pathway 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
579	JAK-STAT signaling pathway 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
580	JAK-STAT signaling pathway 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
581	JAK-STAT signaling pathway 💬	[2] PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
582	JAK-STAT signaling pathway 💬	[2] PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
583	JAK-STAT signaling pathway 💬	[1] PRL 💬	D01348 💬	Terguride	[2] 51, 86 💬
584	Kaposi sarcoma-associated herpesvirus infection 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
585	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
586	Kaposi sarcoma-associated herpesvirus infection 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
587	Kaposi sarcoma-associated herpesvirus infection 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
588	Kaposi sarcoma-associated herpesvirus infection 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
589	Kaposi sarcoma-associated herpesvirus infection 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
590	Leishmaniasis 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
591	Leishmaniasis 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
592	Long-term depression 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
593	Long-term depression 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
594	Long-term depression 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
595	Long-term potentiation 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
596	Long-term potentiation 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
597	Long-term potentiation 💬	[1] CACNA1C 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
598	Long-term potentiation 💬	[1] CACNA1C 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
599	Long-term potentiation 💬	[1] CACNA1C 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
600	Long-term potentiation 💬	[1] CACNA1C 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
601	Long-term potentiation 💬	[1] CACNA1C 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
602	Longevity regulating pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
603	Longevity regulating pathway 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
604	Longevity regulating pathway 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
605	Longevity regulating pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
606	Longevity regulating pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
607	Longevity regulating pathway - multiple species 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
608	Longevity regulating pathway - multiple species 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
609	Longevity regulating pathway - multiple species 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
610	MAPK signaling pathway 💬	[7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
611	MAPK signaling pathway 💬	[7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
612	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
613	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
614	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
615	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
616	MAPK signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
617	MAPK signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
618	MAPK signaling pathway 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
619	MAPK signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
620	MAPK signaling pathway 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
621	MAPK signaling pathway 💬	[2] KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
622	MAPK signaling pathway 💬	[2] KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
623	MAPK signaling pathway 💬	[3] KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
624	MAPK signaling pathway 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
625	MAPK signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
626	Melanogenesis 💬	[1] EDNRB 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
627	Melanogenesis 💬	[1] EDNRB 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
628	Melanogenesis 💬	[1] EDNRB 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
629	Melanogenesis 💬	[1] KIT 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
630	Melanogenesis 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
631	Melanogenesis 💬	[1] KIT 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
632	Melanogenesis 💬	[2] KIT, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
633	Melanogenesis 💬	[2] KIT, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
634	Melanoma 💬	[3] BRAF, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
635	Melanoma 💬	[3] BRAF, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
636	Melanoma 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
637	Melanoma 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
638	Melanoma 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
639	Melanoma 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
640	Metabolic pathways 💬	[1] ANPEP 💬	D00087 💬	Ubenimex	[1] 86 💬
641	Metabolic pathways 💬	[2] ATP4A, ATP4B 💬	D01984 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
642	Metabolic pathways 💬	[2] ATP4A, ATP4B 💬	D04056 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
643	Metabolic pathways 💬	[2] ATP4A, ATP4B 💬	D07917 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
644	Metabolic pathways 💬	[2] ATP4A, ATP4B 💬	D09339 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
645	Metabolic pathways 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
646	Metabolic pathways 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
647	Metabolic pathways 💬	[1] CYP19A1 💬	D00960 💬	Anastrozole	[3] 78, 86, 193 💬
648	Metabolic pathways 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
649	Metabolic pathways 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
650	Metabolic pathways 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
651	Metabolic pathways 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
652	Metabolic pathways 💬	[1] PDE5A 💬	D02008 💬	Tadalafil	[7] 6 , 51, 75, 84, 86, 113, 210 💬
653	Metabolic pathways 💬	[1] PDE5A 💬	D10027 💬	Udenafil	[2] 86, 210 💬
654	Metabolic pathways 💬	[1] PDE5A 💬	D02731 💬	Vardenafil	[3] 13, 86, 299 💬
655	Metabolic pathways 💬	[1] PDE5A 💬	D03260 💬	Vardenafil	[3] 13, 86, 299 💬
656	Metabolic pathways 💬	[1] PDE5A 💬	D08668 💬	Vardenafil	[3] 13, 86, 299 💬
657	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
658	Metabolic pathways 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
659	Metabolic pathways 💬	[1] RRM2 💬	D00341 💬	Hydroxyurea	[8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
660	MicroRNAs in cancer 💬	[2] ABL1, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
661	MicroRNAs in cancer 💬	[2] ABL1, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
662	MicroRNAs in cancer 💬	[3] ABL1, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
663	MicroRNAs in cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
664	MicroRNAs in cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
665	MicroRNAs in cancer 💬	[2] PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
666	MicroRNAs in cancer 💬	[2] PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
667	MicroRNAs in cancer 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
668	MicroRNAs in cancer 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
669	MicroRNAs in cancer 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
670	Morphine addiction 💬	[1] OPRM1 💬	D00842 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
671	Morphine addiction 💬	[1] OPRM1 💬	D02271 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
672	Morphine addiction 💬	[1] OPRM1 💬	D08233 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
673	mTOR signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
674	mTOR signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
675	mTOR signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
676	mTOR signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
677	mTOR signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
678	Natural killer cell mediated cytotoxicity 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
679	Natural killer cell mediated cytotoxicity 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
680	Necroptosis 💬	[1] PARP1 💬	D09730 💬	Olaparib	[2] 86, 285 💬
681	Neuroactive ligand-receptor interaction 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
682	Neuroactive ligand-receptor interaction 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
683	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
684	Neuroactive ligand-receptor interaction 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
685	Neuroactive ligand-receptor interaction 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
686	Neuroactive ligand-receptor interaction 💬	[2] AGTR1, AGTR2 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
687	Neuroactive ligand-receptor interaction 💬	[2] AGTR1, AGTR2 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
688	Neuroactive ligand-receptor interaction 💬	[2] AVPR1A, AVPR2 💬	D01236 💬	Conivaptan	[1] 86 💬
689	Neuroactive ligand-receptor interaction 💬	[2] AVPR1A, AVPR2 💬	D07748 💬	Conivaptan	[1] 86 💬
690	Neuroactive ligand-receptor interaction 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
691	Neuroactive ligand-receptor interaction 💬	[3] DRD2, DRD3, DRD4 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
692	Neuroactive ligand-receptor interaction 💬	[3] DRD2, DRD3, DRD4 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
693	Neuroactive ligand-receptor interaction 💬	[2] DRD2, PRL 💬	D01348 💬	Terguride	[2] 51, 86 💬
694	Neuroactive ligand-receptor interaction 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
695	Neuroactive ligand-receptor interaction 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
696	Neuroactive ligand-receptor interaction 💬	[2] EDNRA, EDNRB 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
697	Neuroactive ligand-receptor interaction 💬	[2] EDNRA, EDNRB 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
698	Neuroactive ligand-receptor interaction 💬	[2] EDNRA, EDNRB 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
699	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬	D00300 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
700	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬	D00669 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
701	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬	D02419 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
702	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬	D03285 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
703	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬	D03360 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
704	Neuroactive ligand-receptor interaction 💬	[1] HRH1 💬	D03854 💬	Diphenhydramine	[8] 11, 49, 51, 70, 86, 96, 222, 256 💬
705	Neuroactive ligand-receptor interaction 💬	[1] HRH2 💬	D00318 💬	Famotidine	[4] 6 , 46, 86, 98 💬
706	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00407 💬	Methylprednisolone	[44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
707	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00751 💬	Methylprednisolone	[44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
708	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00979 💬	Methylprednisolone	[44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
709	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D05000 💬	Methylprednisolone	[44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
710	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D05001 💬	Methylprednisolone	[44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
711	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D05002 💬	Methylprednisolone	[44] 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
712	Neuroactive ligand-receptor interaction 💬	[1] NR3C1 💬	D00473 💬	Prednisone	[47] 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
713	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬	D00842 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
714	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬	D02271 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
715	Neuroactive ligand-receptor interaction 💬	[1] OPRM1 💬	D08233 💬	Morphine	[5] 36, 46, 70, 85, 86 💬
716	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D02720 💬	Beraprost	[1] 86 💬
717	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D00106 💬	Epoprostenol	[1] 86 💬
718	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D01337 💬	Epoprostenol	[1] 86 💬
719	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D02721 💬	Iloprost	[4] 51, 84, 85, 86 💬
720	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D10725 💬	Ralinepag	[1] 86 💬
721	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D09994 💬	Selexipag	[5] 51, 70, 84, 86, 88 💬
722	Neuroactive ligand-receptor interaction 💬	[1] PTGIR 💬	D06213 💬	Treprostinil	[6] 51, 84, 85, 86, 88, 210 💬
723	Neuroactive ligand-receptor interaction 💬	[1] TBXA2R 💬	D04500 💬	Ifetroban	[3] 51, 86, 113 💬
724	Neuroactive ligand-receptor interaction 💬	[1] TRPV1 💬	D00250 💬	Capsaicin	[5] 2 , 6 , 19, 86, 226 💬
725	Neurotrophin signaling pathway 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
726	Neurotrophin signaling pathway 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
727	Neurotrophin signaling pathway 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
728	Neurotrophin signaling pathway 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
729	Neurotrophin signaling pathway 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
730	Neurotrophin signaling pathway 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
731	Neutrophil extracellular trap formation 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
732	Neutrophil extracellular trap formation 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
733	Neutrophil extracellular trap formation 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
734	NF-kappa B signaling pathway 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
735	NF-kappa B signaling pathway 💬	[1] PARP1 💬	D09730 💬	Olaparib	[2] 86, 285 💬
736	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
737	NF-kappa B signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
738	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
739	Nitrogen metabolism 💬	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
740	Non-alcoholic fatty liver disease 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
741	Non-alcoholic fatty liver disease 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
742	Non-alcoholic fatty liver disease 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
743	Non-alcoholic fatty liver disease 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
744	Non-small cell lung cancer 💬	[3] BRAF, RAF1, RET 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
745	Non-small cell lung cancer 💬	[3] BRAF, RAF1, RET 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
746	Non-small cell lung cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
747	Oocyte meiosis 💬	[1] AR 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
748	Osteoclast differentiation 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
749	Osteoclast differentiation 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
750	Osteoclast differentiation 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
751	Ovarian steroidogenesis 💬	[1] CYP19A1 💬	D00960 💬	Anastrozole	[3] 78, 86, 193 💬
752	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
753	Ovarian steroidogenesis 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
754	Oxidative phosphorylation 💬	[2] ATP4A, ATP4B 💬	D01984 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
755	Oxidative phosphorylation 💬	[2] ATP4A, ATP4B 💬	D04056 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
756	Oxidative phosphorylation 💬	[2] ATP4A, ATP4B 💬	D07917 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
757	Oxidative phosphorylation 💬	[2] ATP4A, ATP4B 💬	D09339 💬	Esomeprazole	[6] 13, 46, 86, 98, 298, 299 💬
758	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
759	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
760	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
761	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
762	Oxytocin signaling pathway 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
763	Oxytocin signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
764	Oxytocin signaling pathway 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
765	Oxytocin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
766	Oxytocin signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
767	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
768	Oxytocin signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
769	Oxytocin signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
770	Oxytocin signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
771	p53 signaling pathway 💬	[1] RRM2 💬	D00341 💬	Hydroxyurea	[8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
772	Pancreatic cancer 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
773	Pancreatic cancer 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
774	Pancreatic cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
775	Pancreatic cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
776	Pancreatic cancer 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
777	Pancreatic secretion 💬	[1] CA2 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
778	Pancreatic secretion 💬	[1] CA2 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
779	Pancreatic secretion 💬	[1] CHRM3 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
780	Parathyroid hormone synthesis, secretion and action 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
781	Parathyroid hormone synthesis, secretion and action 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
782	Parathyroid hormone synthesis, secretion and action 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
783	Parkinson disease 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
784	Parkinson disease 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
785	Parkinson disease 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
786	Parkinson disease 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
787	Pathogenic Escherichia coli infection 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
788	Pathogenic Escherichia coli infection 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
789	Pathogenic Escherichia coli infection 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
790	Pathogenic Escherichia coli infection 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
791	Pathways in cancer 💬	[3] ABL1, KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
792	Pathways in cancer 💬	[3] ABL1, KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
793	Pathways in cancer 💬	[4] ABL1, KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
794	Pathways in cancer 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
795	Pathways in cancer 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
796	Pathways in cancer 💬	[3] AR, ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
797	Pathways in cancer 💬	[7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
798	Pathways in cancer 💬	[7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
799	Pathways in cancer 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
800	Pathways in cancer 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
801	Pathways in cancer 💬	[2] EDNRA, EDNRB 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
802	Pathways in cancer 💬	[2] EDNRA, EDNRB 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
803	Pathways in cancer 💬	[2] EDNRA, EDNRB 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
804	Pathways in cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
805	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
806	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
807	Pathways in cancer 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
808	Pathways in cancer 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
809	Pathways in cancer 💬	[1] KEAP1 💬	D03846 💬	Dimethyl fumarate	[4] 13, 51, 86, 296 💬
810	Pathways in cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
811	Pathways in cancer 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
812	Pathways in cancer 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
813	Pathways in cancer 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
814	Pathways in cancer 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
815	Pathways in cancer 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
816	Pathways of neurodegeneration - multiple diseases 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
817	Pathways of neurodegeneration - multiple diseases 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
818	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
819	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
820	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
821	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
822	Pathways of neurodegeneration - multiple diseases 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
823	Pathways of neurodegeneration - multiple diseases 💬	[3] CHRM1, CHRM3, CHRM5 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
824	Pathways of neurodegeneration - multiple diseases 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
825	Pathways of neurodegeneration - multiple diseases 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
826	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
827	Pathways of neurodegeneration - multiple diseases 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
828	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
829	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
830	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
831	PD-L1 expression and PD-1 checkpoint pathway in cancer 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
832	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
833	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
834	Phospholipase D signaling pathway 💬	[2] AVPR1A, AVPR2 💬	D01236 💬	Conivaptan	[1] 86 💬
835	Phospholipase D signaling pathway 💬	[2] AVPR1A, AVPR2 💬	D07748 💬	Conivaptan	[1] 86 💬
836	Phospholipase D signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
837	Phospholipase D signaling pathway 💬	[2] KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
838	Phospholipase D signaling pathway 💬	[2] KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
839	Phospholipase D signaling pathway 💬	[3] KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
840	Phospholipase D signaling pathway 💬	[3] KIT, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
841	Phospholipase D signaling pathway 💬	[3] KIT, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
842	Phospholipase D signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
843	PI3K-Akt signaling pathway 💬	[2] CHRM1, CHRM2 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
844	PI3K-Akt signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
845	PI3K-Akt signaling pathway 💬	[6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
846	PI3K-Akt signaling pathway 💬	[6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
847	PI3K-Akt signaling pathway 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
848	PI3K-Akt signaling pathway 💬	[2] KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
849	PI3K-Akt signaling pathway 💬	[2] KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
850	PI3K-Akt signaling pathway 💬	[3] KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
851	PI3K-Akt signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
852	PI3K-Akt signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
853	PI3K-Akt signaling pathway 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
854	PI3K-Akt signaling pathway 💬	[1] PRL 💬	D01348 💬	Terguride	[2] 51, 86 💬
855	PI3K-Akt signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
856	Platelet activation 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
857	Platelet activation 💬	[1] P2RY12 💬	D00769 💬	Clopidogrel	[2] 49, 86 💬
858	Platelet activation 💬	[1] P2RY12 💬	D07729 💬	Clopidogrel	[2] 49, 86 💬
859	Platelet activation 💬	[1] P2RY12 💬	D10823 💬	Clopidogrel	[2] 49, 86 💬
860	Platelet activation 💬	[1] P2RY12 💬	D10824 💬	Clopidogrel	[2] 49, 86 💬
861	Platelet activation 💬	[1] PTGIR 💬	D02720 💬	Beraprost	[1] 86 💬
862	Platelet activation 💬	[1] PTGIR 💬	D00106 💬	Epoprostenol	[1] 86 💬
863	Platelet activation 💬	[1] PTGIR 💬	D01337 💬	Epoprostenol	[1] 86 💬
864	Platelet activation 💬	[1] PTGIR 💬	D02721 💬	Iloprost	[4] 51, 84, 85, 86 💬
865	Platelet activation 💬	[1] PTGIR 💬	D10725 💬	Ralinepag	[1] 86 💬
866	Platelet activation 💬	[1] PTGIR 💬	D09994 💬	Selexipag	[5] 51, 70, 84, 86, 88 💬
867	Platelet activation 💬	[1] PTGIR 💬	D06213 💬	Treprostinil	[6] 51, 84, 85, 86, 88, 210 💬
868	Platelet activation 💬	[1] PTGS1 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
869	Platelet activation 💬	[1] PTGS1 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
870	Platelet activation 💬	[1] TBXA2R 💬	D04500 💬	Ifetroban	[3] 51, 86, 113 💬
871	Platinum drug resistance 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
872	PPAR signaling pathway 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
873	PPAR signaling pathway 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
874	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
875	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
876	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
877	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
878	Prion disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
879	Progesterone-mediated oocyte maturation 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
880	Progesterone-mediated oocyte maturation 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
881	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
882	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
883	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
884	Prolactin signaling pathway 💬	[2] ESR1, ESR2 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
885	Prolactin signaling pathway 💬	[1] PRL 💬	D01348 💬	Terguride	[2] 51, 86 💬
886	Prolactin signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
887	Prolactin signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
888	Prostate cancer 💬	[1] AR 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
889	Prostate cancer 💬	[3] BRAF, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
890	Prostate cancer 💬	[3] BRAF, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
891	Prostate cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
892	Prostate cancer 💬	[1] IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
893	Prostate cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
894	Prostate cancer 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
895	Prostate cancer 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
896	Prostate cancer 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
897	Protein processing in endoplasmic reticulum 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
898	Proteoglycans in cancer 💬	[3] BRAF, KDR, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
899	Proteoglycans in cancer 💬	[3] BRAF, KDR, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
900	Proteoglycans in cancer 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
901	Proteoglycans in cancer 💬	[1] ESR1 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
902	Proteoglycans in cancer 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
903	Proteoglycans in cancer 💬	[1] ESR1 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
904	Proteoglycans in cancer 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
905	Proteoglycans in cancer 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
906	Proteoglycans in cancer 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
907	Proximal tubule bicarbonate reclamation 💬	[2] CA2, CA4 💬	D00218 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
908	Proximal tubule bicarbonate reclamation 💬	[2] CA2, CA4 💬	D01196 💬	Acetazolamide	[7] 13, 86, 90, 115, 155, 225, 230 💬
909	Purine metabolism 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
910	Purine metabolism 💬	[1] PDE5A 💬	D02229 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
911	Purine metabolism 💬	[1] PDE5A 💬	D08514 💬	Sildenafil	[17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
912	Purine metabolism 💬	[1] PDE5A 💬	D02008 💬	Tadalafil	[7] 6 , 51, 75, 84, 86, 113, 210 💬
913	Purine metabolism 💬	[1] PDE5A 💬	D10027 💬	Udenafil	[2] 86, 210 💬
914	Purine metabolism 💬	[1] PDE5A 💬	D02731 💬	Vardenafil	[3] 13, 86, 299 💬
915	Purine metabolism 💬	[1] PDE5A 💬	D03260 💬	Vardenafil	[3] 13, 86, 299 💬
916	Purine metabolism 💬	[1] PDE5A 💬	D08668 💬	Vardenafil	[3] 13, 86, 299 💬
917	Purine metabolism 💬	[1] RRM2 💬	D00341 💬	Hydroxyurea	[8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
918	Pyrimidine metabolism 💬	[1] RRM2 💬	D00341 💬	Hydroxyurea	[8] 3 , 13, 19, 20, 65, 85, 86, 284 💬
919	Rap1 signaling pathway 💬	[6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
920	Rap1 signaling pathway 💬	[6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
921	Rap1 signaling pathway 💬	[1] DRD2 💬	D01462 💬	Lisuride	[2] 6 , 86 💬
922	Rap1 signaling pathway 💬	[1] DRD2 💬	D08132 💬	Lisuride	[2] 6 , 86 💬
923	Rap1 signaling pathway 💬	[1] DRD2 💬	D01348 💬	Terguride	[2] 51, 86 💬
924	Rap1 signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
925	Rap1 signaling pathway 💬	[2] KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
926	Rap1 signaling pathway 💬	[2] KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
927	Rap1 signaling pathway 💬	[3] KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
928	Rap1 signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
929	Ras signaling pathway 💬	[3] ABL1, KIT, PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
930	Ras signaling pathway 💬	[3] ABL1, KIT, PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
931	Ras signaling pathway 💬	[4] ABL1, KIT, PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
932	Ras signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
933	Ras signaling pathway 💬	[6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
934	Ras signaling pathway 💬	[6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
935	Ras signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
936	Regulation of actin cytoskeleton 💬	[3] BRAF, PDGFRB, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
937	Regulation of actin cytoskeleton 💬	[3] BRAF, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
938	Regulation of actin cytoskeleton 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
939	Regulation of actin cytoskeleton 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
940	Regulation of actin cytoskeleton 💬	[1] PDGFRA 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
941	Regulation of actin cytoskeleton 💬	[1] PDGFRA 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
942	Regulation of actin cytoskeleton 💬	[2] PDGFRA, PDGFRB 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
943	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
944	Regulation of lipolysis in adipocytes 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
945	Regulation of lipolysis in adipocytes 💬	[2] ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
946	Regulation of lipolysis in adipocytes 💬	[2] ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
947	Regulation of lipolysis in adipocytes 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
948	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
949	Regulation of lipolysis in adipocytes 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
950	Relaxin signaling pathway 💬	[1] EDNRB 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
951	Relaxin signaling pathway 💬	[1] EDNRB 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
952	Relaxin signaling pathway 💬	[1] EDNRB 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
953	Relaxin signaling pathway 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
954	Relaxin signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
955	Relaxin signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
956	Relaxin signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
957	Renal cell carcinoma 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
958	Renal cell carcinoma 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
959	Renal cell carcinoma 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
960	Renin secretion 💬	[1] ACE 💬	D00251 💬	Captopril	[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬
961	Renin secretion 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
962	Renin secretion 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
963	Renin secretion 💬	[2] ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
964	Renin secretion 💬	[2] ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
965	Renin secretion 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
966	Renin secretion 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
967	Renin secretion 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
968	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
969	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
970	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
971	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
972	Renin secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
973	Renin secretion 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
974	Renin secretion 💬	[1] EDNRA 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
975	Renin secretion 💬	[1] EDNRA 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
976	Renin secretion 💬	[1] EDNRA 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
977	Renin secretion 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
978	Renin secretion 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
979	Renin-angiotensin system 💬	[1] ACE 💬	D00251 💬	Captopril	[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬
980	Renin-angiotensin system 💬	[2] AGTR1, AGTR2 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
981	Renin-angiotensin system 💬	[2] AGTR1, AGTR2 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
982	Renin-angiotensin system 💬	[1] ANPEP 💬	D00087 💬	Ubenimex	[1] 86 💬
983	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
984	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
985	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
986	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
987	Retrograde endocannabinoid signaling 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
988	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
989	Retrograde endocannabinoid signaling 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
990	Rheumatoid arthritis 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
991	Salivary secretion 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
992	Salivary secretion 💬	[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
993	Salivary secretion 💬	[1] ADRB1 💬	D00634 💬	Bisoprolol	[3] 67, 86, 113 💬
994	Salivary secretion 💬	[1] ADRB1 💬	D02342 💬	Bisoprolol	[3] 67, 86, 113 💬
995	Salivary secretion 💬	[1] ADRB2 💬	D02147 💬	Salbutamol	[14] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
996	Salivary secretion 💬	[1] CHRM3 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
997	Salivary secretion 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
998	Salmonella infection 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
999	Salmonella infection 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1000	Serotonergic synapse 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1001	Serotonergic synapse 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1002	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
1003	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
1004	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
1005	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
1006	Serotonergic synapse 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
1007	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
1008	Serotonergic synapse 💬	[2] PTGS1, PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
1009	Serotonergic synapse 💬	[1] SLC6A4 💬	D00326 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
1010	Serotonergic synapse 💬	[1] SLC6A4 💬	D00823 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
1011	Shigellosis 💬	[1] EGFR 💬	D03455 💬	Cetuximab	[5] 34, 51, 86, 89, 331 💬
1012	Shigellosis 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
1013	Shigellosis 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
1014	Signaling pathways regulating pluripotency of stem cells 💬	[1] ACVR2A 💬	D09670 💬	Sotatercept	[2] 86, 284 💬
1015	Signaling pathways regulating pluripotency of stem cells 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1016	Signaling pathways regulating pluripotency of stem cells 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1017	Small cell lung cancer 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
1018	Small cell lung cancer 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
1019	Sphingolipid signaling pathway 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
1020	Sphingolipid signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1021	Sphingolipid signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1022	Spinocerebellar ataxia 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
1023	Spinocerebellar ataxia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
1024	Steroid hormone biosynthesis 💬	[1] CYP19A1 💬	D00960 💬	Anastrozole	[3] 78, 86, 193 💬
1025	Synaptic vesicle cycle 💬	[1] SLC6A4 💬	D00326 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
1026	Synaptic vesicle cycle 💬	[1] SLC6A4 💬	D00823 💬	Fluoxetine	[6] 13, 17, 78, 86, 179, 206 💬
1027	T cell receptor signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1028	T cell receptor signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1029	Taste transduction 💬	[1] CACNA1C 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
1030	Taste transduction 💬	[1] CACNA1C 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
1031	Taste transduction 💬	[1] CACNA1C 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
1032	Taste transduction 💬	[1] CACNA1C 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
1033	Taste transduction 💬	[1] CACNA1C 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
1034	Taste transduction 💬	[1] CHRM3 💬	D02212 💬	Ipratropium	[2] 6 , 86 💬
1035	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00358 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
1036	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D02086 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
1037	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08127 💬	Lidocaine	[12] 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
1038	Taste transduction 💬	[2] TAS1R2, TAS1R3 💬	D02381 💬	Aspartame	[5] 6 , 13, 67, 86, 230 💬
1039	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
1040	TGF-beta signaling pathway 💬	[1] ACVR2A 💬	D09670 💬	Sotatercept	[2] 86, 284 💬
1041	Th17 cell differentiation 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
1042	Th17 cell differentiation 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
1043	Th17 cell differentiation 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
1044	Thermogenesis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
1045	Thermogenesis 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
1046	Thermogenesis 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
1047	Thermogenesis 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
1048	Thermogenesis 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
1049	Thermogenesis 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
1050	Thyroid cancer 💬	[2] BRAF, RET 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1051	Thyroid cancer 💬	[2] BRAF, RET 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1052	Thyroid cancer 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
1053	Thyroid cancer 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
1054	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
1055	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
1056	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00966 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
1057	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[4] 2 , 86, 113, 227 💬
1058	Thyroid hormone signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
1059	Thyroid hormone signaling pathway 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1060	Thyroid hormone signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1061	Tight junction 💬	[1] CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
1062	Tight junction 💬	[1] CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
1063	Tight junction 💬	[1] CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
1064	Tight junction 💬	[1] CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
1065	Tight junction 💬	[1] CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
1066	Tight junction 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
1067	Tight junction 💬	[2] PRKAA1, PRKAA2 💬	D00944 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
1068	Tight junction 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[21] 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
1069	TNF signaling pathway 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
1070	TNF signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
1071	TNF signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
1072	Transcriptional misregulation in cancer 💬	[1] FLT3 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1073	Transcriptional misregulation in cancer 💬	[1] FLT3 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1074	Transcriptional misregulation in cancer 💬	[1] IL1R2 💬	D02934 💬	Anakinra	[19] 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
1075	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D00945 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
1076	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
1077	Tuberculosis 💬	[1] RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1078	Tuberculosis 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1079	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
1080	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
1081	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
1082	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
1083	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
1084	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D01303 💬	Flunarizine	[4] 58, 86, 149, 215 💬
1085	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D07971 💬	Flunarizine	[4] 58, 86, 149, 215 💬
1086	Type II diabetes mellitus 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
1087	Ubiquitin mediated proteolysis 💬	[1] KEAP1 💬	D03846 💬	Dimethyl fumarate	[4] 13, 51, 86, 296 💬
1088	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D00255 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
1089	Vascular smooth muscle contraction 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D03415 💬	Carvedilol	[5] 6 , 57, 86, 113, 210 💬
1090	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D00150 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
1091	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D02014 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬
1092	Vascular smooth muscle contraction 💬	[1] AVPR1A 💬	D01236 💬	Conivaptan	[1] 86 💬
1093	Vascular smooth muscle contraction 💬	[1] AVPR1A 💬	D07748 💬	Conivaptan	[1] 86 💬
1094	Vascular smooth muscle contraction 💬	[2] BRAF, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1095	Vascular smooth muscle contraction 💬	[2] BRAF, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1096	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00616 💬	Diltiazem	[3] 51, 58, 86 💬
1097	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D03830 💬	Diltiazem	[3] 51, 58, 86 💬
1098	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
1099	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00617 💬	Nicardipine	[2] 70, 86 💬
1100	Vascular smooth muscle contraction 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
1101	Vascular smooth muscle contraction 💬	[1] EDNRA 💬	D07077 💬	Ambrisentan	[7] 51, 84, 85, 86, 88, 210, 211 💬
1102	Vascular smooth muscle contraction 💬	[1] EDNRA 💬	D01227 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
1103	Vascular smooth muscle contraction 💬	[1] EDNRA 💬	D07538 💬	Bosentan	[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
1104	Vascular smooth muscle contraction 💬	[1] EDNRA 💬	D10135 💬	Macitentan	[5] 51, 85, 86, 88, 210 💬
1105	Vascular smooth muscle contraction 💬	[1] EDNRA 💬	D07171 💬	Sitaxentan	[1] 86 💬
1106	Vascular smooth muscle contraction 💬	[3] GUCY1A1, GUCY1A2, GUCY1B1 💬	D09572 💬	Riociguat	[6] 51, 84, 86, 88, 225, 299 💬
1107	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D02720 💬	Beraprost	[1] 86 💬
1108	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D00106 💬	Epoprostenol	[1] 86 💬
1109	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D01337 💬	Epoprostenol	[1] 86 💬
1110	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D02721 💬	Iloprost	[4] 51, 84, 85, 86 💬
1111	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D10725 💬	Ralinepag	[1] 86 💬
1112	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D09994 💬	Selexipag	[5] 51, 70, 84, 86, 88 💬
1113	Vascular smooth muscle contraction 💬	[1] PTGIR 💬	D06213 💬	Treprostinil	[6] 51, 84, 85, 86, 88, 210 💬
1114	Vasopressin-regulated water reabsorption 💬	[1] AVPR2 💬	D01236 💬	Conivaptan	[1] 86 💬
1115	Vasopressin-regulated water reabsorption 💬	[1] AVPR2 💬	D07748 💬	Conivaptan	[1] 86 💬
1116	VEGF signaling pathway 💬	[2] KDR, RAF1 💬	D06272 💬	Sorafenib	[2] 34, 86 💬
1117	VEGF signaling pathway 💬	[2] KDR, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
1118	VEGF signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[16] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
1119	VEGF signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 34, 46, 49, 51, 86, 96, 97, 113, 158, 210, 231, 251 💬
1120	VEGF signaling pathway 💬	[1] VEGFA 💬	D06409 💬	Bevacizumab	[9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
1121	Viral myocarditis 💬	[1] ABL1 💬	D01441 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
1122	Viral myocarditis 💬	[1] ABL1 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
1123	Viral myocarditis 💬	[1] ABL1 💬	D08953 💬	Nilotinib	[5] 6 , 8 , 34, 51, 86 💬
1124	Viral protein interaction with cytokine and cytokine receptor 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[18] 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬