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Target Gene/Pathway💬 Info on mouse-over

e.g. Sirolimus, Adalimumab, MAP2K

ABCDEFGH I JKLMNOPQRSTUVWXYZother

131 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related		 KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [2] PML, RARA 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
2 Adherens junction 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
3 Adherens junction 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
4 Adipocytokine signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
5 Adipocytokine signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
6 Adipocytokine signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
7 African trypanosomiasis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
8 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
9 Allograft rejection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10 Alzheimer disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
11 Amoebiasis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
12 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
13 Amyotrophic lateral sclerosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
14 Antifolate resistance 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
15 Antifolate resistance 💬
 [1] TYMS 💬 D01223 💬 Capecitabine [1] 94 💬
16 Antigen processing and presentation 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
17 Apoptosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
18 Arrhythmogenic right ventricular cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
19 Asthma 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
20 Bile secretion 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
21 Bile secretion 💬
 [1] NR1H4 💬 D00734 💬 Ursodeoxycholic acid [13]  6 ,  8 , 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
22 Bladder cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
23 Bladder cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
24 Breast cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
25 Breast cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
26 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
27 Calcium signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
28 Calcium signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
29 cAMP signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
30 cAMP signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
31 Cell adhesion molecules 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
32 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
33 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
34 Chagas disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
35 Chemokine signaling pathway 💬
 [2] CCR2, CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
36 Choline metabolism in cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
37 Choline metabolism in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
38 Colorectal cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
39 Colorectal cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
40 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
41 Coronavirus disease - COVID-19 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
42 Coronavirus disease - COVID-19 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
43 Cushing syndrome 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
44 Cushing syndrome 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
45 Cytokine-cytokine receptor interaction 💬
 [2] CCR2, CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
46 Cytokine-cytokine receptor interaction 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
47 Diabetic cardiomyopathy 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
48 Diabetic cardiomyopathy 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
49 Dilated cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
50 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
51 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
52 Drug metabolism - other enzymes 💬
 [1] RRM1 💬 D01370 💬 Cladribine [2] 13, 94 💬
53 ECM-receptor interaction 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
54 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
55 EGFR tyrosine kinase inhibitor resistance 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
56 Endocrine resistance 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
57 Endocrine resistance 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
58 Endocytosis 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
59 Endocytosis 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
60 Endocytosis 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
61 Endocytosis 💬
 [1] PML 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
62 Endometrial cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
63 Endometrial cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
64 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
65 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
66 Epstein-Barr virus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
67 ErbB signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
68 ErbB signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
69 Estrogen signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
70 Estrogen signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
71 Estrogen signaling pathway 💬
 [1] RARA 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
72 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
73 Fluid shear stress and atherosclerosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
74 Focal adhesion 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
75 Focal adhesion 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
76 Focal adhesion 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
77 FoxO signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
78 FoxO signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
79 Gap junction 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
80 Gap junction 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
81 Gastric cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
82 Gastric cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
83 Gastric cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
84 Glioma 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
85 Glioma 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
86 Glucagon signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
87 Glucagon signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
88 Glutathione metabolism 💬
 [1] RRM1 💬 D01370 💬 Cladribine [2] 13, 94 💬
89 GnRH signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
90 GnRH signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
91 Graft-versus-host disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
92 Hematopoietic cell lineage 💬
 [1] ITGA4 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
93 Hematopoietic cell lineage 💬
 [1] MS4A1 💬 D02994 💬 Rituximab [47] 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
94 Hematopoietic cell lineage 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
95 Hepatitis B 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
96 Hepatitis C 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
97 Hepatitis C 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
98 Hepatitis C 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
99 Hepatitis C 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
100 Hepatitis C 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
101 Hepatocellular carcinoma 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
102 Hepatocellular carcinoma 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
103 Herpes simplex virus 1 infection 💬
 [1] PML 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
104 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
105 HIF-1 signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
106 HIF-1 signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
107 Human cytomegalovirus infection 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
108 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
109 Human cytomegalovirus infection 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
110 Human cytomegalovirus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
111 Human immunodeficiency virus 1 infection 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
112 Human immunodeficiency virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
113 Human papillomavirus infection 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
114 Human papillomavirus infection 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
115 Human papillomavirus infection 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
116 Human papillomavirus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
117 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
118 Hypertrophic cardiomyopathy 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
119 Hypertrophic cardiomyopathy 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
120 IL-17 signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
121 Inflammatory bowel disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
122 Influenza A 💬
 [1] PML 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
123 Influenza A 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
124 Insulin resistance 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
125 Insulin resistance 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
126 Insulin resistance 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
127 Intestinal immune network for IgA production 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
128 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
129 JAK-STAT signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
130 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
131 Legionellosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
132 Leishmaniasis 💬
 [1] ITGA4 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
133 Leishmaniasis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
134 Leukocyte transendothelial migration 💬
 [1] ITGA4 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
135 Malaria 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
136 MAPK signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
137 MAPK signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
138 MAPK signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
139 Melanoma 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
140 Melanoma 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
141 Metabolic pathways 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
142 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
143 Metabolic pathways 💬
 [1] RRM1 💬 D01370 💬 Cladribine [2] 13, 94 💬
144 Metabolic pathways 💬
 [1] TYMS 💬 D01223 💬 Capecitabine [1] 94 💬
145 MicroRNAs in cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
146 MicroRNAs in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
147 mTOR signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
148 Natural killer cell mediated cytotoxicity 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
149 Necroptosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
150 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00246 💬 Budesonide [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
151 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
152 NOD-like receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
153 Non-alcoholic fatty liver disease 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
154 Non-alcoholic fatty liver disease 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
155 Non-alcoholic fatty liver disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
156 Non-small cell lung cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
157 Non-small cell lung cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
158 Non-small cell lung cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
159 One carbon pool by folate 💬
 [1] TYMS 💬 D01223 💬 Capecitabine [1] 94 💬
160 Osteoclast differentiation 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
161 Oxytocin signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
162 Oxytocin signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
163 Pancreatic cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
164 Pancreatic cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
165 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
166 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
167 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
168 Pathways in cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
169 Pathways in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
170 Pathways in cancer 💬
 [3] PML, RARA, RARB 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
171 Pathways of neurodegeneration - multiple diseases 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
172 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
173 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
174 Pertussis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
175 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
176 Phospholipase D signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
177 PI3K-Akt signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
178 PI3K-Akt signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
179 PI3K-Akt signaling pathway 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
180 PPAR signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [6] 20, 93, 94, 160, 316, 324 💬
181 PPAR signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
182 Prion disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
183 Prostate cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
184 Prostate cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
185 Proteoglycans in cancer 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
186 Proteoglycans in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
187 Proteoglycans in cancer 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
188 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
189 Purine metabolism 💬
 [1] RRM1 💬 D01370 💬 Cladribine [2] 13, 94 💬
190 Pyrimidine metabolism 💬
 [1] RRM1 💬 D01370 💬 Cladribine [2] 13, 94 💬
191 Pyrimidine metabolism 💬
 [1] TYMS 💬 D01223 💬 Capecitabine [1] 94 💬
192 Rap1 signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
193 Rap1 signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
194 Ras signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
195 Ras signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
196 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
197 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
198 Regulation of actin cytoskeleton 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
199 Relaxin signaling pathway 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
200 Relaxin signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
201 Rheumatoid arthritis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
202 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
203 Salmonella infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
204 Shigellosis 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
205 Shigellosis 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
206 Shigellosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
207 Small cell lung cancer 💬
 [1] RARB 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
208 Sphingolipid signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
209 Systemic lupus erythematosus 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
210 T cell receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
211 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
212 TGF-beta signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
213 Th17 cell differentiation 💬
 [1] RARA 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
214 TNF signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
215 Toll-like receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
216 Toxoplasmosis 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
217 Toxoplasmosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
218 Transcriptional misregulation in cancer 💬
 [1] ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
219 Transcriptional misregulation in cancer 💬
 [2] PML, RARA 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
220 Tuberculosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
221 Type I diabetes mellitus 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
222 Type II diabetes mellitus 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
223 Ubiquitin mediated proteolysis 💬
 [1] PML 💬 D00094 💬 Tretinoin [5]  2 , 63, 75, 94, 231 💬
224 Viral carcinogenesis 💬
 [1] CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
225 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] CCR2, CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
226 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
227 Yersinia infection 💬
 [1] ITGA4 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
228 Yersinia infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

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