DDrare: Database of Drug Development for Rare Diseases

Depot leuprolide acetate 3.75 mg (DrugBank: Leuprolide, Acetate)

5 diseases

ID	Disease name (Link within this page)	Number of trials
1	Spinal and bulbar muscular atrophy	0
2	Amyotrophic lateral sclerosis	0
3	Spinal muscular atrophy	0
51	Scleroderma	1
76	Pituitary gonadotropin secretion hyperthyroidism	0

1. Spinal and bulbar muscular atrophy [ 17 clinical trials, 16 drugs, (DrugBank: 8 drugs), 10 drug target genes, 15 drug target pathways]

Searched query = "Spinal and bulbar muscular atrophy", "Spinobulbar muscular atrophy", "SBMA", "Kennedy disease", "Kennedy-Alter-Sung syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 17 trial found

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 508 trial found

3. Spinal muscular atrophy [ 179 clinical trials, 102 drugs, (DrugBank: 26 drugs), 52 drug target genes, 78 drug target pathways]

Searched query = "Spinal muscular atrophy", "Myelopathic muscular atrophy", "SMA I", "Werdnig-Hoffman disease", "SMA II", "Dubowitz disease", "SMA III", "Kugelberg-Welander disease", "SMA IV"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 179 trial found

51. Scleroderma [ 466 clinical trials, 536 drugs, (DrugBank: 142 drugs), 110 drug target genes, 210 drug target pathways]

Searched query = "Scleroderma", "Systemic sclerosis", "SSc", "dcSSc", "lcSSc"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 466 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01257802 (ClinicalTrials.gov)	May 2011	9/12/2010	GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases	GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases	Lupus Erythematosus, Systemic;Systemic Vasculitis;Isolated Angiitis of Central Nervous System;Lung Disease With Systemic Sclerosis;Lung Disease Interstitial Diffuse	Drug: depot leuprolide acetate 3.75 mg;Drug: Placebo	Joseph Mccune	National Institutes of Health (NIH);Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Terminated	18 Years	40 Years	Female	14	Phase 3	United States

76. Pituitary gonadotropin secretion hyperthyroidism [ 25 clinical trials, 41 drugs, (DrugBank: 11 drugs), 3 drug target genes, 10 drug target pathways]

Searched query = "Pituitary gonadotropin secretion hyperthyroidism", "Gonadotropin secreting pituitary adenoma", "Central precocious puberty", "Gonadotropin producing pituitary adenoma"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 25 trial found