DDrare: Database of Drug Development for Rare Diseases

Leuprolide (gnrh agonists) (DrugBank: Leuprolide, GnRH)

5 diseases

ID	Disease name (Link within this page)	Number of trials
1	Spinal and bulbar muscular atrophy	0
2	Amyotrophic lateral sclerosis	0
3	Spinal muscular atrophy	0
51	Scleroderma	0
76	Pituitary gonadotropin secretion hyperthyroidism	1

1. Spinal and bulbar muscular atrophy [ 17 clinical trials, 16 drugs, (DrugBank: 8 drugs), 10 drug target genes, 15 drug target pathways]

Searched query = "Spinal and bulbar muscular atrophy", "Spinobulbar muscular atrophy", "SBMA", "Kennedy disease", "Kennedy-Alter-Sung syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 17 trial found

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 508 trial found

3. Spinal muscular atrophy [ 179 clinical trials, 102 drugs, (DrugBank: 26 drugs), 52 drug target genes, 78 drug target pathways]

Searched query = "Spinal muscular atrophy", "Myelopathic muscular atrophy", "SMA I", "Werdnig-Hoffman disease", "SMA II", "Dubowitz disease", "SMA III", "Kugelberg-Welander disease", "SMA IV"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 179 trial found

51. Scleroderma [ 466 clinical trials, 536 drugs, (DrugBank: 142 drugs), 110 drug target genes, 210 drug target pathways]

Searched query = "Scleroderma", "Systemic sclerosis", "SSc", "dcSSc", "lcSSc"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 466 trial found

76. Pituitary gonadotropin secretion hyperthyroidism [ 25 clinical trials, 41 drugs, (DrugBank: 11 drugs), 3 drug target genes, 10 drug target pathways]

Searched query = "Pituitary gonadotropin secretion hyperthyroidism", "Gonadotropin secreting pituitary adenoma", "Central precocious puberty", "Gonadotropin producing pituitary adenoma"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 25 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00438217 (ClinicalTrials.gov)	May 2006	21/2/2007	Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children	Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children	Central Precocious Puberty	Drug: Triptorelin (GnRH agonists);Drug: Leuprolide (GnRH agonists)	University of Pisa	NULL	Recruiting	1 Year	18 Years	Both	100	Phase 4	Italy