DDrare: Database of Drug Development for Rare Diseases

S.c. injections of bovine intestinal alkaline phosphatase (DrugBank: Alkaline Phosphatase)

4 diseases

ID	Disease name (Link within this page)	Number of trials
46	Malignant rheumatoid arthritis	1
93	Primary biliary cholangitis [Primary biliary cirrhosis (~Mar 2017)]	0
97	Ulcerative colitis	0
172	Hypophosphatasia	0

46. Malignant rheumatoid arthritis [ 4,183 clinical trials, 2,538 drugs, (DrugBank: 401 drugs), 183 drug target genes, 219 drug target pathways]

Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 4,183 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01416493 (ClinicalTrials.gov)	May 2011	11/8/2011	Bovine Intestinal Alkaline Phosphatase (bIAP) Modulating Rheumatoid Arthritis	An OPEN LABEL Phase II Safety Study of Bovine Intestinal Alkaline Phosphatase (bIAP), an Inflammation Modulating Moiety, in RA Patients	Acute Rheumatoid Arthritis	Drug: s.c. injections of bovine intestinal Alkaline Phosphatase	Alloksys Life Sciences B.V.	Aix Scientifics	Completed	18 Years	N/A	Both	6	Phase 1;Phase 2	United Kingdom

93. Primary biliary cholangitis [Primary biliary cirrhosis (~Mar 2017)] [ 230 clinical trials, 215 drugs, (DrugBank: 51 drugs), 34 drug target genes, 107 drug target pathways]

Searched query = "Primary biliary cholangitis", "Primary biliary cirrhosis", "PBC"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 230 trial found

97. Ulcerative colitis [ 2,269 clinical trials, 1,331 drugs, (DrugBank: 241 drugs), 114 drug target genes, 181 drug target pathways]

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,269 trial found

172. Hypophosphatasia [ 32 clinical trials, 18 drugs, (DrugBank: 4 drugs), 3 drug target genes, 6 drug target pathways]

Searched query = "Hypophosphatasia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 32 trial found