DDrare: Database of Drug Development for Rare Diseases

Other: 13c6 leucine (DrugBank: Leucine)

3 diseases

ID	Disease name (Link within this page)	Number of trials
5	Progressive supranuclear palsy	1
7	Corticobasal degeneration	1
127	Frontotemporal lobar degeneration	1

5. Progressive supranuclear palsy [ 82 clinical trials, 107 drugs, (DrugBank: 36 drugs), 60 drug target genes, 90 drug target pathways]

Searched query = "Progressive supranuclear palsy", "PSP"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 82 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03545126 (ClinicalTrials.gov)	August 21, 2017	12/3/2018	Human CNS Tau Kinetics in Tauopathies	Human CNS Tau Kinetics in Tauopathies	Progressive Supranuclear Palsy (PSP);Corticobasal Degeneration (CBD);Frontotemporal Dementia (FTD MAPT Mutation)	Other: 13C6 Leucine	Washington University School of Medicine	Association of Frontotemporal Degeneration;Tau Consortium	Recruiting	18 Years	N/A	All	32		United States

7. Corticobasal degeneration [ 16 clinical trials, 33 drugs, (DrugBank: 11 drugs), 6 drug target genes, 13 drug target pathways]

Searched query = "Corticobasal degeneration", "Corticobasal syndrome", "CBD"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 16 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03545126 (ClinicalTrials.gov)	August 21, 2017	12/3/2018	Human CNS Tau Kinetics in Tauopathies	Human CNS Tau Kinetics in Tauopathies	Progressive Supranuclear Palsy (PSP);Corticobasal Degeneration (CBD);Frontotemporal Dementia (FTD MAPT Mutation)	Other: 13C6 Leucine	Washington University School of Medicine	Association of Frontotemporal Degeneration;Tau Consortium	Recruiting	18 Years	N/A	All	32		United States

127. Frontotemporal lobar degeneration [ 74 clinical trials, 83 drugs, (DrugBank: 28 drugs), 29 drug target genes, 99 drug target pathways]

Searched query = "Frontotemporal lobar degeneration", "Frontotemporal dementia", "Semantic dementia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 74 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03545126 (ClinicalTrials.gov)	August 21, 2017	12/3/2018	Human CNS Tau Kinetics in Tauopathies	Human CNS Tau Kinetics in Tauopathies	Progressive Supranuclear Palsy (PSP);Corticobasal Degeneration (CBD);Frontotemporal Dementia (FTD MAPT Mutation)	Other: 13C6 Leucine	Washington University School of Medicine	Association of Frontotemporal Degeneration;Tau Consortium	Recruiting	18 Years	N/A	All	32		United States