DDrare: Database of Drug Development for Rare Diseases

Grapefruit juice (DrugBank: Grapefruit)

5 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	0
46	Malignant rheumatoid arthritis	1
50	Dermatomyositis	1
83	Addison disease	1
97	Ulcerative colitis	1

6. Parkinson disease [ 2,123 clinical trials, 2,046 drugs, (DrugBank: 324 drugs), 183 drug target genes, 198 drug target pathways]

Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,123 trial found

46. Malignant rheumatoid arthritis [ 4,183 clinical trials, 2,538 drugs, (DrugBank: 401 drugs), 183 drug target genes, 219 drug target pathways]

Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 4,183 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus		rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulcerative colitis	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan

50. Dermatomyositis [ 157 clinical trials, 207 drugs, (DrugBank: 76 drugs), 47 drug target genes, 142 drug target pathways]

Searched query = "Dermatomyositis", "Polymyositis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 157 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus		rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulcerative colitis	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan

83. Addison disease [ 20 clinical trials, 42 drugs, (DrugBank: 13 drugs), 6 drug target genes, 17 drug target pathways]

Searched query = "Addison disease", "Primary chronic adrenocortical insufficiency", "Autoimmune polyglandular syndrome", "Hypoparathyroidism-Addison-Monilia syndrome", "HAM syndrome", "Schmidt syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 20 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01271296 (ClinicalTrials.gov)	April 2008	22/12/2010	Effects and Interactions of Liquorice and Grapefruit on Glucocorticoid Replacement Therapy in Addison's Disease	Use of Liquorice and Grapefruit in Patients With Addison's Disease	Addison Disease	Dietary Supplement: Liquorice;Dietary Supplement: Grapefruit Juice	Haukeland University Hospital	NULL	Completed	18 Years	80 Years	Both	17	N/A	Norway

97. Ulcerative colitis [ 2,269 clinical trials, 1,331 drugs, (DrugBank: 241 drugs), 114 drug target genes, 181 drug target pathways]

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 2,269 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013546	2014/06/01	31/03/2014	The effect ofgrepefruit juice on the patients with autoimmune diseases taking tacrolimus		rheumatoid arthritis, lupus nephritis, polymyositis/dermatomyositis with interstitial pneumonia, ulcerative colitis	take a glass of grapefruit juice every day do not take grapefruit juice	Department of Rheumatology and Clinical Immunology, Kyoto University Hospital	NULL	Pending	16years-old	80years-old	Male and Female	20	Not applicable	Japan