DDrare: Database of Drug Development for Rare Diseases

Bupropion hydrochloride (DrugBank: Bupropion)

5 diseases

ID	Disease name (Link within this page)	Number of trials
8	Huntington disease	0
18	Spinocerebellar degeneration	0
21	Mitochondrial disease	0
96	Crohn disease	0
171	Wilson disease	1

8. Huntington disease [ 197 clinical trials, 171 drugs, (DrugBank: 54 drugs), 82 drug target genes, 144 drug target pathways]

Searched query = "Huntington disease", "Huntington chorea"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 197 trial found

18. Spinocerebellar degeneration [ 59 clinical trials, 78 drugs, (DrugBank: 28 drugs), 44 drug target genes, 59 drug target pathways]

Searched query = "Spinocerebellar degeneration", "SCD", "Spinocerebellar ataxia type I", "SCA1", "Spinocerebellar ataxia type II", "SCA2", "Spinocerebellar ataxia type III", "SCA3", "Machado-Joseph disease", "Spinocerebellar ataxia type VI", "SCA6", "Spinocerebellar ataxia type VII", "SCA7", "Spinocerebellar ataxia type X", "SCA10", "Spinocerebellar ataxia type XII", "SCA12", "Dentatorubural pallidoluysian atrophy", "Dentatorubropallidoluysial atrophy", "DRPLA", "Naito-Koyanagi disease", "Friedreich ataxia", "FRDA", "Ataxia with vitamin E deficiency", "AVED", "Early-onset ataxia with ocular motor ataxia and hypoalbuminemia", "EOAH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 59 trial found

21. Mitochondrial disease [ 23 clinical trials, 29 drugs, (DrugBank: 28 drugs), 44 drug target genes, 65 drug target pathways]

Searched query = "Mitochondrial disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 23 trial found

96. Crohn disease [ 2,209 clinical trials, 1,276 drugs, (DrugBank: 240 drugs), 166 drug target genes, 210 drug target pathways]

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,209 trial found

171. Wilson disease [ 50 clinical trials, 59 drugs, (DrugBank: 17 drugs), 3 drug target genes, 28 drug target pathways]

Searched query = "Wilson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 50 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04526210 (ClinicalTrials.gov)	August 2020	19/8/2020	Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants	A Phase 1, Randomized, 2-Period, 2-Sequence, Cross-over Study to Determine the Effect of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants	Wilson Disease	Drug: ALXN1840;Drug: Bupropion Hydrochloride	Alexion Pharmaceuticals	NULL	Enrolling by invitation	18 Years	50 Years	All	38	Phase 1	United States