Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | 
|---|---|---|---|---|---|
| 1 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 7 diseases in DDrare  | 
ABCC8 1件: ABCC8 💬 | 
D00294 D00294 💬 | 
Diazoxide | 013 2件: 13, 193 💬 | 
| 2 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 4 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 5 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 6 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 7 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 81 drugs (DrugBank) and 73 diseases in DDrare  | 
CACNA1C 5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 8 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 9 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00146 D00146 💬 | 
Corticotropin | 002 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 | 
| 10 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 11 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 12 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare  | 
CACNA1C 6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 13 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 14 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare  | 
GRIA1 2件: GRIA1, GRIA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 15 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 16 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 17 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 18 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 19 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 42 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 20 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 21 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 22 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 23 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 24 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 25 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 26 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D07229 D07229 💬 | 
Carbetocin | 193 1件: 193 💬 | 
| 27 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D00089 D00089 💬 | 
Oxytocin | 006 6件:  6 , 72, 127, 193, 206, 226 💬 | 
| 28 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 29 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 30 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 31 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
CACNA1C 8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 32 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
GLP1R 1件: GLP1R 💬 | 
D04121 D04121 💬 | 
Exenatide | 006 6件:  6 , 17, 72, 78, 193, 233 💬 | 
| 33 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
GLP1R 1件: GLP1R 💬 | 
D06404 D06404 💬 | 
Liraglutide | 006 3件:  6 , 75, 193 💬 | 
| 34 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00146 D00146 💬 | 
Corticotropin | 002 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 | 
| 35 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D07229 D07229 💬 | 
Carbetocin | 193 1件: 193 💬 | 
| 36 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D00089 D00089 💬 | 
Oxytocin | 006 6件:  6 , 72, 127, 193, 206, 226 💬 | 
| 37 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D00442 D00442 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 38 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D06495 D06495 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 39 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare  | 
CACNA1D 1件: CACNA1D 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 40 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 41 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare  | 
CACNA1D 1件: CACNA1D 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 42 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 43 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 44 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
ADRA2A 1件: ADRA2A 💬 | 
D00606 D00606 💬 | 
Guanfacine | 193 1件: 193 💬 | 
| 45 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
ADRA2A 1件: ADRA2A 💬 | 
D08031 D08031 💬 | 
Guanfacine | 193 1件: 193 💬 | 
| 46 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 47 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 48 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 49 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 50 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 51 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 52 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 53 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 54 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 55 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 56 | Cholinergic synapse 💬 Related to 31 target genes, 51 drugs (DrugBank) and 62 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 57 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare  | 
CACNA1C 6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 58 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare  | 
GRIA2 1件: GRIA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 59 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 60 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 61 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 62 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D00410 D00410 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 63 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D05019 D05019 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 64 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00146 D00146 💬 | 
Corticotropin | 002 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 | 
| 65 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 66 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D00410 D00410 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 67 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D05019 D05019 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 68 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00146 D00146 💬 | 
Corticotropin | 002 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 | 
| 69 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare  | 
GHR 1件: GHR 💬 | 
D02691 D02691 💬 | 
Somatotropin | 002 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 | 
| 70 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 71 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 72 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 73 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 74 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 75 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare  | 
CACNA1C 7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 76 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 77 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 78 | ErbB signaling pathway 💬 Related to 12 target genes, 22 drugs (DrugBank) and 52 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 79 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare  | 
CACNA1C 20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 80 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 81 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 82 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 83 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 84 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D00442 D00442 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 85 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D06495 D06495 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 86 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 87 | Glioma 💬 Related to 14 target genes, 26 drugs (DrugBank) and 57 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 88 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare  | 
CACNA1C 11件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 89 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 90 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare  | 
KCNJ11 1件: KCNJ11 💬 | 
D00294 D00294 💬 | 
Diazoxide | 013 2件: 13, 193 💬 | 
| 91 | GnRH signaling pathway 💬 Related to 15 target genes, 34 drugs (DrugBank) and 38 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 92 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 93 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare  | 
GHR 1件: GHR 💬 | 
D02691 D02691 💬 | 
Somatotropin | 002 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 | 
| 94 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 95 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D00442 D00442 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 96 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D06495 D06495 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 97 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 98 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 99 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 100 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 101 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 102 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 103 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare  | 
GRIA1 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 104 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 105 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 106 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 107 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare  | 
ABCC8 2件: ABCC8, KCNJ11 💬 | 
D00294 D00294 💬 | 
Diazoxide | 013 2件: 13, 193 💬 | 
| 108 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 109 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare  | 
GLP1R 1件: GLP1R 💬 | 
D04121 D04121 💬 | 
Exenatide | 006 6件:  6 , 17, 72, 78, 193, 233 💬 | 
| 110 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare  | 
GLP1R 1件: GLP1R 💬 | 
D06404 D06404 💬 | 
Liraglutide | 006 3件:  6 , 75, 193 💬 | 
| 111 | Insulin signaling pathway 💬 Related to 12 target genes, 24 drugs (DrugBank) and 64 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 112 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare  | 
GHR 1件: GHR 💬 | 
D02691 D02691 💬 | 
Somatotropin | 002 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 | 
| 113 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 114 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 115 | Long-term depression 💬 Related to 12 target genes, 17 drugs (DrugBank) and 33 diseases in DDrare  | 
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 116 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare  | 
CACNA1C 3件: CACNA1C, GRIA1, GRIA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 117 | Longevity regulating pathway 💬 Related to 11 target genes, 18 drugs (DrugBank) and 65 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 118 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 14 drugs (DrugBank) and 59 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 119 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 120 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare  | 
CA2 2件: CA2, CA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 121 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D00410 D00410 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 122 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D05019 D05019 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 123 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare  | 
CYP19A1 1件: CYP19A1 💬 | 
D00960 D00960 💬 | 
Anastrozole | 078 3件: 78, 86, 193 💬 | 
| 124 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 125 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare  | 
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 126 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 127 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
ADRA2A 1件: ADRA2A 💬 | 
D00606 D00606 💬 | 
Guanfacine | 193 1件: 193 💬 | 
| 128 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
ADRA2A 1件: ADRA2A 💬 | 
D08031 D08031 💬 | 
Guanfacine | 193 1件: 193 💬 | 
| 129 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 130 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 131 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 132 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D05731 D05731 💬 | 
Rimonabant | 193 1件: 193 💬 | 
| 133 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
CNR1 2件: CNR1, CNR2 💬 | 
D10915 D10915 💬 | 
Cannabidiol | 002 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 | 
| 134 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
GABRA1 25件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 135 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
GHR 1件: GHR 💬 | 
D02691 D02691 💬 | 
Somatotropin | 002 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 | 
| 136 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
GLP1R 1件: GLP1R 💬 | 
D04121 D04121 💬 | 
Exenatide | 006 6件:  6 , 17, 72, 78, 193, 233 💬 | 
| 137 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
GLP1R 1件: GLP1R 💬 | 
D06404 D06404 💬 | 
Liraglutide | 006 3件:  6 , 75, 193 💬 | 
| 138 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
HRH3 1件: HRH3 💬 | 
D10749 D10749 💬 | 
Pitolisant | 006 3件:  6 , 113, 193 💬 | 
| 139 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00146 D00146 💬 | 
Corticotropin | 002 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬 | 
| 140 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D07229 D07229 💬 | 
Carbetocin | 193 1件: 193 💬 | 
| 141 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D00089 D00089 💬 | 
Oxytocin | 006 6件:  6 , 72, 127, 193, 206, 226 💬 | 
| 142 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D00442 D00442 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 143 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
SSTR2 1件: SSTR2 💬 | 
D06495 D06495 💬 | 
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 | 
| 144 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 145 | Nicotine addiction 💬 Related to 30 target genes, 33 drugs (DrugBank) and 43 diseases in DDrare  | 
GABRA1 20件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 146 | Nitrogen metabolism 💬 Related to 14 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare  | 
CA2 2件: CA2, CA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 147 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare  | 
CYP19A1 1件: CYP19A1 💬 | 
D00960 D00960 💬 | 
Anastrozole | 078 3件: 78, 86, 193 💬 | 
| 148 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 149 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D07229 D07229 💬 | 
Carbetocin | 193 1件: 193 💬 | 
| 150 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare  | 
OXTR 1件: OXTR 💬 | 
D00089 D00089 💬 | 
Oxytocin | 006 6件:  6 , 72, 127, 193, 206, 226 💬 | 
| 151 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 152 | Pancreatic secretion 💬 Related to 12 target genes, 38 drugs (DrugBank) and 39 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 153 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 154 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
CACNA1C 8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 155 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 156 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 157 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 158 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare  | 
GHR 1件: GHR 💬 | 
D02691 D02691 💬 | 
Somatotropin | 002 23件:  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 | 
| 159 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 160 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 161 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 162 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 163 | Proximal tubule bicarbonate reclamation 💬 Related to 6 target genes, 6 drugs (DrugBank) and 19 diseases in DDrare  | 
CA2 2件: CA2, CA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 164 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D10915 D10915 💬 | 
Cannabidiol | 002 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 | 
| 165 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D05731 D05731 💬 | 
Rimonabant | 193 1件: 193 💬 | 
| 166 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 167 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 168 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 169 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 170 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 171 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 172 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 173 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare  | 
CACNA1C 24件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 174 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D10915 D10915 💬 | 
Cannabidiol | 002 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 | 
| 175 | Retrograde endocannabinoid signaling 💬 Related to 33 target genes, 63 drugs (DrugBank) and 67 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D05731 D05731 💬 | 
Rimonabant | 193 1件: 193 💬 | 
| 176 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D00601 D00601 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 177 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D02358 D02358 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 178 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare  | 
ADRB1 1件: ADRB1 💬 | 
D05011 D05011 💬 | 
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 | 
| 179 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare  | 
CACNA1C 7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 180 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 181 | Spinocerebellar ataxia 💬 Related to 16 target genes, 23 drugs (DrugBank) and 68 diseases in DDrare  | 
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 182 | Spinocerebellar ataxia 💬 Related to 16 target genes, 23 drugs (DrugBank) and 68 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 183 | Steroid hormone biosynthesis 💬 Related to 7 target genes, 10 drugs (DrugBank) and 14 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D00410 D00410 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 184 | Steroid hormone biosynthesis 💬 Related to 7 target genes, 10 drugs (DrugBank) and 14 diseases in DDrare  | 
CYP11B1 1件: CYP11B1 💬 | 
D05019 D05019 💬 | 
Metyrapone | 075 2件: 75, 193 💬 | 
| 185 | Steroid hormone biosynthesis 💬 Related to 7 target genes, 10 drugs (DrugBank) and 14 diseases in DDrare  | 
CYP19A1 1件: CYP19A1 💬 | 
D00960 D00960 💬 | 
Anastrozole | 078 3件: 78, 86, 193 💬 | 
| 186 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare  | 
CACNA1C 10件: CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 187 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 188 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D10915 D10915 💬 | 
Cannabidiol | 002 19件:  2 ,  6 ,  8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 | 
| 189 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare  | 
CNR1 1件: CNR1 💬 | 
D05731 D05731 💬 | 
Rimonabant | 193 1件: 193 💬 | 
| 190 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 191 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 192 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare  | 
CACNA1D 1件: CACNA1D 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 193 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare  | 
GRIA3 1件: GRIA3 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 194 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare  | 
ABCC8 2件: ABCC8, KCNJ11 💬 | 
D00294 D00294 💬 | 
Diazoxide | 013 2件: 13, 193 💬 | 
| 195 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare  | 
CACNA1C 2件: CACNA1C, CACNA1D 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 196 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 197 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare  | 
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 |