Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | 
|---|---|---|---|---|---|
| 1 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00284 D00284 💬 | 
Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬 | 
| 2 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare  | 
ESR1 2件: ESR1, ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 3 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00284 D00284 💬 | 
Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬 | 
| 4 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare  | 
AR 3件: AR, ESR1, ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 5 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00284 D00284 💬 | 
Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬 | 
| 6 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00284 D00284 💬 | 
Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬 | 
| 7 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare  | 
ESR1 1件: ESR1 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 8 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare  | 
ESR1 2件: ESR1, ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 9 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare  | 
ESR1 2件: ESR1, ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 10 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare  | 
ESR2 1件: ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 11 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare  | 
MS4A1 1件: MS4A1 💬 | 
D02994 D02994 💬 | 
Rituximab | 006 49件:  6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 | 
| 12 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
MC2R 1件: MC2R 💬 | 
D00284 D00284 💬 | 
Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬 | 
| 13 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00244 D00244 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 14 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00972 D00972 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 15 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D01357 D01357 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 16 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D01402 D01402 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 17 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D01637 D01637 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 18 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D02032 D02032 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 19 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D02286 D02286 💬 | 
Betamethasone | 002 7件:  2 , 28, 46, 83, 90, 96, 235 💬 | 
| 20 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00088 D00088 💬 | 
Hydrocortisone | 006 11件:  6 , 41, 46, 53, 75, 78, 81, 83, 97, 98, 299 💬 | 
| 21 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00976 D00976 💬 | 
Hydrocortisone cypionate | 006 3件:  6 , 81, 83 💬 | 
| 22 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D01442 D01442 💬 | 
Hydrocortisone succinate | 006 3件:  6 , 81, 83 💬 | 
| 23 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00407 D00407 💬 | 
Methylprednisolone | 002 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 | 
| 24 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00751 D00751 💬 | 
Methylprednisolone | 002 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 | 
| 25 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D00979 D00979 💬 | 
Methylprednisolone | 002 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 | 
| 26 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D05000 D05000 💬 | 
Methylprednisolone | 002 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 | 
| 27 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D05001 D05001 💬 | 
Methylprednisolone | 002 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 | 
| 28 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare  | 
NR3C1 1件: NR3C1 💬 | 
D05002 D05002 💬 | 
Methylprednisolone | 002 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 | 
| 29 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare  | 
AR 1件: AR 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 30 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare  | 
AR 3件: AR, ESR1, ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 31 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare  | 
ESR1 2件: ESR1, ESR2 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 32 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare  | 
AR 1件: AR 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 33 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare  | 
ESR1 1件: ESR1 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 | 
| 34 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare  | 
ESR1 1件: ESR1 💬 | 
D08409 D08409 💬 | 
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |