Target Gene/Pathway Pathway / Gene
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| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | 
|---|---|---|---|---|---|
| 1 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
CSF2 1件: CSF2 💬 | 
D11343 D11343 💬 | 
Otilimab | 046 2件: 46, 256 💬 | 
| 2 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IFNG 1件: IFNG 💬 | 
D11120 D11120 💬 | 
Emapalumab | 049 2件: 49, 107 💬 | 
| 3 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IFNG 1件: IFNG 💬 | 
D04242 D04242 💬 | 
Fontolizumab | 046 1件: 46 💬 | 
| 4 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL10 4件: IL10, IL1B, IL6, TNF 💬 | 
D01583 D01583 💬 | 
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 | 
| 5 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL12A 2件: IL12A, IL12B 💬 | 
D09214 D09214 💬 | 
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 | 
| 6 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL1B 1件: IL1B 💬 | 
D09315 D09315 💬 | 
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 | 
| 7 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL1B 1件: IL1B 💬 | 
D09911 D09911 💬 | 
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 | 
| 8 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL1B 1件: IL1B 💬 | 
D06635 D06635 💬 | 
Rilonacept | 051 4件: 51, 106, 107, 266 💬 | 
| 9 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL1R1 2件: IL1R1, IL1R2 💬 | 
D02934 D02934 💬 | 
Anakinra | 002 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 | 
| 10 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D09669 D09669 💬 | 
Siltuximab | 028 2件: 28, 331 💬 | 
| 11 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D10080 D10080 💬 | 
Sirukumab | 041 2件: 41, 46 💬 | 
| 12 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
IL6 2件: IL6, TNF 💬 | 
D08976 D08976 💬 | 
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 | 
| 13 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
NFKB1 1件: NFKB1 💬 | 
D01146 D01146 💬 | 
Iguratimod | 046 4件: 46, 51, 53, 271 💬 | 
| 14 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 | 
D11158 D11158 💬 | 
Leniolisib | 053 2件: 53, 65 💬 | 
| 15 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
PIK3CD 1件: PIK3CD 💬 | 
D11437 D11437 💬 | 
Parsaclisib | 035 3件: 35, 53, 61 💬 | 
| 16 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
RELA 1件: RELA 💬 | 
D12181 D12181 💬 | 
Edasalonexent | 113 1件: 113 💬 | 
| 17 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬 | 
D09620 D09620 💬 | 
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 | 
| 18 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D02597 D02597 💬 | 
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 | 
| 19 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D03441 D03441 💬 | 
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 | 
| 20 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D00742 D00742 💬 | 
Etanercept | 015 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 | 
| 21 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D04358 D04358 💬 | 
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 | 
| 22 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D02598 D02598 💬 | 
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 | 
| 23 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D04687 D04687 💬 | 
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 | 
| 24 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D09944 D09944 💬 | 
Ozoralizumab | 046 1件: 46 💬 | 
| 25 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D05393 D05393 💬 | 
Pegsunercept | 046 1件: 46 💬 | 
| 26 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare  | 
TNF 1件: TNF 💬 | 
D00754 D00754 💬 | 
Thalidomide | 002 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |