Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
| 2 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
| 3 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 4 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 5 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
CDK4 1件: CDK4 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
| 6 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 5件: 34, 51, 86, 89, 331 💬 |
| 7 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 1件: 94 💬 |
| 8 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
| 9 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
| 10 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
| 11 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 12 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 13 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 14 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
| 15 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
| 16 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 4件: 13, 46, 49, 299 💬 |
| 17 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 1件: 74 💬 |
| 18 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 1件: 74 💬 |
| 19 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 1件: 53 💬 |
| 20 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 1件: 53 💬 |
| 21 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 22 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 23 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01617 D01617 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 24 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01953 D01953 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 25 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D04061 D04061 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 26 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D04063 D04063 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 27 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D04064 D04064 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 28 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D04065 D04065 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
| 29 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
| 30 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 2件: 13, 227 💬 |
| 31 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 2件: 13, 227 💬 |
| 32 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
| 33 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 2件: 46, 49 💬 |
| 34 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
| 35 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D02217 D02217 💬 |
Raloxifene | 046 1件: 46 💬 |
| 36 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 1件: 46 💬 |
| 37 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 4件: 2 , 86, 113, 227 💬 |
| 38 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 2件: ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 4件: 2 , 86, 113, 227 💬 |
| 39 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
| 40 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 41 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 42 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
| 43 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 44 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 45 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 46 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 47 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
| 48 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
| 49 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 50 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 51 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 4件: 13, 34, 89, 331 💬 |
| 52 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 53 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 54 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
SRC 1件: SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 2件: 2 , 67 💬 |
| 55 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
SRC 1件: SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 56 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
SRC 1件: SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 57 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
SRC 1件: SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 3件: 6 , 89, 272 💬 |