Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | 
|---|---|---|---|---|---|
| 1 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
BRAF 1件: BRAF 💬 | 
D10064 D10064 💬 | 
Dabrafenib | 034 1件: 34 💬 | 
| 2 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
BRAF 2件: BRAF, RAF1 💬 | 
D06272 D06272 💬 | 
Sorafenib | 034 2件: 34, 86 💬 | 
| 3 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
BRAF 2件: BRAF, RAF1 💬 | 
D08524 D08524 💬 | 
Sorafenib | 034 2件: 34, 86 💬 | 
| 4 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D03455 D03455 💬 | 
Cetuximab | 034 5件: 34, 51, 86, 89, 331 💬 | 
| 5 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D04023 D04023 💬 | 
Erlotinib | 094 1件: 94 💬 | 
| 6 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D07907 D07907 💬 | 
Erlotinib | 094 1件: 94 💬 | 
| 7 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D01977 D01977 💬 | 
Gefitinib | 075 1件: 75 💬 | 
| 8 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D11251 D11251 💬 | 
Icotinib | 034 1件: 34 💬 | 
| 9 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D04024 D04024 💬 | 
Lapatinib | 034 3件: 34, 74, 75 💬 | 
| 10 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D08108 D08108 💬 | 
Lapatinib | 034 3件: 34, 74, 75 💬 | 
| 11 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
EGFR 1件: EGFR 💬 | 
D11772 D11772 💬 | 
Tesevatinib | 067 1件: 67 💬 | 
| 12 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IGF1R 1件: IGF1R 💬 | 
D09925 D09925 💬 | 
Linsitinib | 232 1件: 232 💬 | 
| 13 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IGF1R 1件: IGF1R 💬 | 
D03297 D03297 💬 | 
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 | 
| 14 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IGF1R 1件: IGF1R 💬 | 
D04870 D04870 💬 | 
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 | 
| 15 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IGF1R 1件: IGF1R 💬 | 
D09680 D09680 💬 | 
Teprotumumab | 051 1件: 51 💬 | 
| 16 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IL10 2件: IL10, IL6 💬 | 
D01583 D01583 💬 | 
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 | 
| 17 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D08976 D08976 💬 | 
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 | 
| 18 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D09669 D09669 💬 | 
Siltuximab | 028 2件: 28, 331 💬 | 
| 19 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D10080 D10080 💬 | 
Sirukumab | 041 2件: 41, 46 💬 | 
| 20 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
INSR 1件: INSR 💬 | 
D04539 D04539 💬 | 
Insulin detemir | 299 1件: 299 💬 | 
| 21 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
INSR 1件: INSR 💬 | 
D03250 D03250 💬 | 
Insulin glargine | 299 1件: 299 💬 | 
| 22 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
INSR 1件: INSR 💬 | 
D00085 D00085 💬 | 
Insulin human | 096 2件: 96, 156 💬 | 
| 23 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
INSR 1件: INSR 💬 | 
D03230 D03230 💬 | 
Insulin human | 096 2件: 96, 156 💬 | 
| 24 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
MAP2K1 2件: MAP2K1, MAP2K2 💬 | 
D10604 D10604 💬 | 
Binimetinib | 034 1件: 34 💬 | 
| 25 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
MAP2K1 2件: MAP2K1, MAP2K2 💬 | 
D10405 D10405 💬 | 
Cobimetinib | 280 1件: 280 💬 | 
| 26 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
MAP2K1 2件: MAP2K1, MAP2K2 💬 | 
D09666 D09666 💬 | 
Selumetinib | 034 1件: 34 💬 | 
| 27 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
MAP2K1 2件: MAP2K1, MAP2K2 💬 | 
D10175 D10175 💬 | 
Trametinib | 002 4件:  2 , 34, 279, 280 💬 | 
| 28 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 | 
D09639 D09639 💬 | 
Losmapimod | 113 2件: 113, 222 💬 | 
| 29 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 | 
D10959 D10959 💬 | 
Neflamapimod | 008 1件:  8  💬 | 
| 30 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 | 
D11158 D11158 💬 | 
Leniolisib | 053 2件: 53, 65 💬 | 
| 31 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
PIK3CD 1件: PIK3CD 💬 | 
D11437 D11437 💬 | 
Parsaclisib | 035 3件: 35, 53, 61 💬 | 
| 32 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
PLK1 1件: PLK1 💬 | 
D10154 D10154 💬 | 
Rigosertib | 036 1件: 36 💬 | 
| 33 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
PRKAA1 2件: PRKAA1, PRKAA2 💬 | 
D00944 D00944 💬 | 
Metformin | 002 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 | 
| 34 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
PRKAA1 2件: PRKAA1, PRKAA2 💬 | 
D04966 D04966 💬 | 
Metformin | 002 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 | 
| 35 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
S1PR1 1件: S1PR1 💬 | 
D11283 D11283 💬 | 
Cenerimod | 049 1件: 49 💬 | 
| 36 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
S1PR1 1件: S1PR1 💬 | 
D10001 D10001 💬 | 
Fingolimod | 013 3件: 13, 14, 156 💬 | 
| 37 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
S1PR1 1件: S1PR1 💬 | 
D11215 D11215 💬 | 
Ponesimod | 013 1件: 13 💬 | 
| 38 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
S1PR1 1件: S1PR1 💬 | 
D11460 D11460 💬 | 
Siponimod | 013 2件: 13, 50 💬 | 
| 39 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
S1PR1 2件: S1PR1, S1PR4 💬 | 
D10930 D10930 💬 | 
Etrasimod | 096 3件: 96, 97, 98 💬 | 
| 40 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
S1PR1 2件: S1PR1, S1PR4 💬 | 
D10968 D10968 💬 | 
Ozanimod | 013 3件: 13, 96, 97 💬 | 
| 41 | FoxO signaling pathway 💬 Related to 24 target genes, 35 drugs (DrugBank) and 54 diseases in DDrare  | 
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬 | 
D09620 D09620 💬 | 
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 |