Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
2 Apelin signaling pathway 💬
 1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
3 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00522 💬 Candesartan 2件: 58, 67 💬
4 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00522 💬 Candesartan cilexetil 1件: 67 💬
5 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00626 💬 Candesartan cilexetil 1件: 67 💬
6 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00523 💬 Irbesartan 4件: 66, 167, 168, 222 💬
7 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
8 Apelin signaling pathway 💬
 1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
9 Apelin signaling pathway 💬
 1件: AGTR1 💬 D11776 💬 Sparsentan 3件: 66, 218, 222 💬
10 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00627 💬 Telmisartan 2件: 66, 67 💬
11 Apelin signaling pathway 💬
 1件: AGTR1 💬 D00400 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬
12 Apelin signaling pathway 💬
 1件: CCN2 💬 D10969 💬 Pamrevlumab 2件: 85, 113 💬
13 Apelin signaling pathway 💬
 2件: HDAC4, HDAC5 💬 D06320 💬 Vorinostat 3件: 19, 75, 96 💬
14 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
15 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
16 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
17 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
18 Apelin signaling pathway 💬
 1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
19 Apelin signaling pathway 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
20 Apelin signaling pathway 💬
 1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
21 Apelin signaling pathway 💬
 1件: PDE3B 💬 D00227 💬 Aminophylline 1件: 63 💬
22 Apelin signaling pathway 💬
 1件: PDE3B 💬 D05429 💬 Aminophylline 1件: 63 💬
23 Apelin signaling pathway 💬
 1件: PDE3B 💬 D07546 💬 Bucladesine 1件: 246 💬
24 Apelin signaling pathway 💬
 1件: PDE3B 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
25 Apelin signaling pathway 💬
 1件: PDE3B 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
26 Apelin signaling pathway 💬
 1件: PDE3B 💬 D01896 💬 Cilostazol 3件: 51, 70, 124 💬
27 Apelin signaling pathway 💬
 1件: PDE3B 💬 D00718 💬 Flavoxate 1件: 226 💬
28 Apelin signaling pathway 💬
 1件: PDE3B 💬 D07961 💬 Flavoxate 1件: 226 💬
29 Apelin signaling pathway 💬
 1件: PDE3B 💬 D01385 💬 Ibudilast 2件:  2 , 13 💬
30 Apelin signaling pathway 💬
 1件: PDE3B 💬 D04720 💬 Levosimendan 1件:  2  💬
31 Apelin signaling pathway 💬
 1件: PDE3B 💬 D00417 💬 Milrinone 1件: 294 💬
32 Apelin signaling pathway 💬
 1件: PDE3B 💬 D02085 💬 Milrinone 1件: 294 💬
33 Apelin signaling pathway 💬
 1件: PDE3B 💬 D00371 💬 Theophylline 2件: 236, 299 💬
34 Apelin signaling pathway 💬
 1件: PDE3B 💬 D01712 💬 Theophylline 2件: 236, 299 💬
35 Apelin signaling pathway 💬
 1件: PDE3B 💬 D02017 💬 Theophylline 2件: 236, 299 💬
36 Apelin signaling pathway 💬
 1件: PDE3B 💬 D06103 💬 Theophylline 2件: 236, 299 💬
37 Apelin signaling pathway 💬
 1件: PDE3B 💬 D06104 💬 Theophylline 2件: 236, 299 💬
38 Apelin signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
39 Apelin signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
40 Apelin signaling pathway 💬
 1件: PRKCE 💬 D09671 💬 Sotrastaurin 1件: 97 💬
41 Apelin signaling pathway 💬
 1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
42 Apelin signaling pathway 💬
 1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬