Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | 
|---|---|---|---|---|---|
| 1 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
CD3D 3件: CD3D, CD3E, CD3G 💬 | 
D05092 D05092 💬 | 
Muromonab | 060 3件: 60, 96, 97 💬 | 
| 2 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
CD3D 3件: CD3D, CD3E, CD3G 💬 | 
D08959 D08959 💬 | 
Otelixizumab | 046 1件: 46 💬 | 
| 3 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
CD3D 3件: CD3D, CD3E, CD3G 💬 | 
D06314 D06314 💬 | 
Visilizumab | 096 2件: 96, 97 💬 | 
| 4 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
CD3E 1件: CD3E 💬 | 
D11463 D11463 💬 | 
Mosunetuzumab | 049 1件: 49 💬 | 
| 5 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
HLA-DMA 14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 | 
D04318 D04318 💬 | 
Glatiramer | 002 4件:  2 , 13, 96, 156 💬 | 
| 6 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IFNG 1件: IFNG 💬 | 
D11120 D11120 💬 | 
Emapalumab | 049 2件: 49, 107 💬 | 
| 7 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IFNG 1件: IFNG 💬 | 
D04242 D04242 💬 | 
Fontolizumab | 046 1件: 46 💬 | 
| 8 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IFNGR1 2件: IFNGR1, IFNGR2 💬 | 
D00747 D00747 💬 | 
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 | 
| 9 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL17A 1件: IL17A 💬 | 
D10071 D10071 💬 | 
Ixekizumab | 036 6件: 36, 37, 107, 162, 269, 271 💬 | 
| 10 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL17A 1件: IL17A 💬 | 
D09967 D09967 💬 | 
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 | 
| 11 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL17A 1件: IL17A 💬 | 
D11127 D11127 💬 | 
Tibulizumab | 053 1件: 53 💬 | 
| 12 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL17A 2件: IL17A, IL17F 💬 | 
D11550 D11550 💬 | 
Bimekizumab | 046 3件: 46, 97, 271 💬 | 
| 13 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL1B 1件: IL1B 💬 | 
D09315 D09315 💬 | 
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 | 
| 14 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL1B 1件: IL1B 💬 | 
D09911 D09911 💬 | 
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 | 
| 15 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL1B 1件: IL1B 💬 | 
D06635 D06635 💬 | 
Rilonacept | 051 4件: 51, 106, 107, 266 💬 | 
| 16 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL1B 2件: IL1B, IL6 💬 | 
D01583 D01583 💬 | 
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 | 
| 17 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL1R1 1件: IL1R1 💬 | 
D02934 D02934 💬 | 
Anakinra | 002 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 | 
| 18 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL22 1件: IL22 💬 | 
D11953 D11953 💬 | 
Efmarodocokin alfa | 096 2件: 96, 97 💬 | 
| 19 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL23A 1件: IL23A 💬 | 
D10912 D10912 💬 | 
Brazikumab | 096 2件: 96, 97 💬 | 
| 20 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL23A 1件: IL23A 💬 | 
D10438 D10438 💬 | 
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 | 
| 21 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL23A 1件: IL23A 💬 | 
D11123 D11123 💬 | 
Mirikizumab | 037 3件: 37, 96, 97 💬 | 
| 22 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL23A 1件: IL23A 💬 | 
D11052 D11052 💬 | 
Risankizumab | 037 4件: 37, 96, 97, 271 💬 | 
| 23 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL23A 1件: IL23A 💬 | 
D10400 D10400 💬 | 
Tildrakizumab | 162 2件: 162, 271 💬 | 
| 24 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL23A 1件: IL23A 💬 | 
D09214 D09214 💬 | 
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 | 
| 25 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL2RA 1件: IL2RA 💬 | 
D03058 D03058 💬 | 
Basiliximab | 002 6件:  2 , 50, 66, 97, 222, 228 💬 | 
| 26 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL2RA 1件: IL2RA 💬 | 
D03639 D03639 💬 | 
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 | 
| 27 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 | 
D00748 D00748 💬 | 
Aldesleukin | 002 6件:  2 , 35, 49, 65, 96, 97 💬 | 
| 28 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL4 1件: IL4 💬 | 
D03117 D03117 💬 | 
Binetrakin | 046 1件: 46 💬 | 
| 29 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL4R 1件: IL4R 💬 | 
D10354 D10354 💬 | 
Dupilumab | 051 4件: 51, 98, 160, 162 💬 | 
| 30 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D08976 D08976 💬 | 
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 | 
| 31 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D09669 D09669 💬 | 
Siltuximab | 028 2件: 28, 331 💬 | 
| 32 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL6 1件: IL6 💬 | 
D10080 D10080 💬 | 
Sirukumab | 041 2件: 41, 46 💬 | 
| 33 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL6R 1件: IL6R 💬 | 
D10161 D10161 💬 | 
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 | 
| 34 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL6R 1件: IL6R 💬 | 
D11079 D11079 💬 | 
Satralizumab | 011 2件: 11, 13 💬 | 
| 35 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
IL6R 1件: IL6R 💬 | 
D02596 D02596 💬 | 
Tocilizumab | 002 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 | 
| 36 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 1件: JAK1 💬 | 
D10871 D10871 💬 | 
Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬 | 
| 37 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 1件: JAK1 💬 | 
D10944 D10944 💬 | 
Itacitinib | 046 5件: 46, 51, 60, 97, 228 💬 | 
| 38 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 1件: JAK1 💬 | 
D10994 D10994 💬 | 
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 | 
| 39 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 2件: JAK1, JAK2 💬 | 
D10308 D10308 💬 | 
Baricitinib | 041 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 | 
| 40 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 2件: JAK1, JAK2 💬 | 
D09959 D09959 💬 | 
Ruxolitinib | 228 1件: 228 💬 | 
| 41 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 3件: JAK1, JAK2, JAK3 💬 | 
D10653 D10653 💬 | 
Peficitinib | 046 1件: 46 💬 | 
| 42 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 | 
D09970 D09970 💬 | 
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 | 
| 43 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
LCK 1件: LCK 💬 | 
D03658 D03658 💬 | 
Dasatinib | 051 2件: 51, 85 💬 | 
| 44 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
LCK 1件: LCK 💬 | 
D06414 D06414 💬 | 
Dasatinib | 051 2件: 51, 85 💬 | 
| 45 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 | 
D09639 D09639 💬 | 
Losmapimod | 113 2件: 113, 222 💬 | 
| 46 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 | 
D10959 D10959 💬 | 
Neflamapimod | 008 1件:  8  💬 | 
| 47 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D02714 D02714 💬 | 
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 | 
| 48 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D00753 D00753 💬 | 
Sirolimus | 002 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 | 
| 49 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
MTOR 1件: MTOR 💬 | 
D06068 D06068 💬 | 
Temsirolimus | 013 4件: 13, 34, 89, 331 💬 | 
| 50 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
NFKB1 1件: NFKB1 💬 | 
D01146 D01146 💬 | 
Iguratimod | 046 4件: 46, 51, 53, 271 💬 | 
| 51 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | 
D00184 D00184 💬 | 
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 | 
| 52 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | 
D05480 D05480 💬 | 
Pimecrolimus | 160 1件: 160 💬 | 
| 53 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | 
D00107 D00107 💬 | 
Tacrolimus | 002 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 | 
| 54 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | 
D08556 D08556 💬 | 
Tacrolimus | 002 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 | 
| 55 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | 
D09033 D09033 💬 | 
Voclosporin | 222 1件: 222 💬 | 
| 56 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
PRKCQ 1件: PRKCQ 💬 | 
D09671 D09671 💬 | 
Sotrastaurin | 097 1件: 97 💬 | 
| 57 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 1件: RARA 💬 | 
D04162 D04162 💬 | 
Fenretinide | 299 1件: 299 💬 | 
| 58 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 1件: RARA 💬 | 
D00348 D00348 💬 | 
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 | 
| 59 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 1件: RARA 💬 | 
D01418 D01418 💬 | 
Tamibarotene | 026 2件: 26, 96 💬 | 
| 60 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 1件: RARA 💬 | 
D00094 D00094 💬 | 
Tretinoin | 002 6件:  2 , 62, 63, 75, 94, 231 💬 | 
| 61 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 1件: RARA 💬 | 
D06543 D06543 💬 | 
Vitamin A | 013 3件: 13, 53, 90 💬 | 
| 62 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 4件: RARA, RXRA, RXRB, RXRG 💬 | 
D02754 D02754 💬 | 
Acitretin | 037 1件: 37 💬 | 
| 63 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RARA 4件: RARA, RXRA, RXRB, RXRG 💬 | 
D02815 D02815 💬 | 
Alitretinoin | 049 1件: 49 💬 | 
| 64 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RELA 1件: RELA 💬 | 
D12181 D12181 💬 | 
Edasalonexent | 113 1件: 113 💬 | 
| 65 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
RXRA 3件: RXRA, RXRB, RXRG 💬 | 
D03106 D03106 💬 | 
Bexarotene | 013 2件: 13, 75 💬 | 
| 66 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
TGFB1 1件: TGFB1 💬 | 
D09620 D09620 💬 | 
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 | 
| 67 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare  | 
TYK2 1件: TYK2 💬 | 
D11817 D11817 💬 | 
Deucravacitinib | 096 2件: 96, 97 💬 |