Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related  | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | 
|---|---|---|---|---|---|
| 1 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 | 
D00297 D00297 💬 | 
Digitoxin | 299 1件: 299 💬 | 
| 2 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 | 
D00298 D00298 💬 | 
Digoxin | 008 3件:  8 , 46, 210 💬 | 
| 3 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00218 D00218 💬 | 
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 | 
| 4 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D01196 D01196 💬 | 
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 | 
| 5 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00518 D00518 💬 | 
Diclofenamide | 114 1件: 114 💬 | 
| 6 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00653 D00653 💬 | 
Dorzolamide | 090 1件: 90 💬 | 
| 7 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D07871 D07871 💬 | 
Dorzolamide | 090 1件: 90 💬 | 
| 8 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CA2 1件: CA2 💬 | 
D00537 D00537 💬 | 
Topiramate | 006 6件:  6 , 97, 140, 144, 156, 193 💬 | 
| 9 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CFTR 1件: CFTR 💬 | 
D11423 D11423 💬 | 
Deutivacaftor | 299 1件: 299 💬 | 
| 10 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CFTR 1件: CFTR 💬 | 
D11507 D11507 💬 | 
Elexacaftor | 299 1件: 299 💬 | 
| 11 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CFTR 1件: CFTR 💬 | 
D11724 D11724 💬 | 
Galicaftor | 299 1件: 299 💬 | 
| 12 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CFTR 1件: CFTR 💬 | 
D09916 D09916 💬 | 
Ivacaftor | 299 1件: 299 💬 | 
| 13 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CFTR 1件: CFTR 💬 | 
D10134 D10134 💬 | 
Lumacaftor | 299 1件: 299 💬 | 
| 14 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
CFTR 1件: CFTR 💬 | 
D11041 D11041 💬 | 
Tezacaftor | 299 1件: 299 💬 | 
| 15 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D00887 D00887 💬 | 
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 | 
| 16 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D07474 D07474 💬 | 
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 | 
| 17 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D00892 D00892 💬 | 
Fluvastatin | 079 3件: 79, 218, 222 💬 | 
| 18 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D07983 D07983 💬 | 
Fluvastatin | 079 3件: 79, 218, 222 💬 | 
| 19 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D00359 D00359 💬 | 
Lovastatin | 006 11件:  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 | 
| 20 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D00893 D00893 💬 | 
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 | 
| 21 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D08410 D08410 💬 | 
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 | 
| 22 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D01915 D01915 💬 | 
Rosuvastatin | 006 11件:  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 | 
| 23 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D08492 D08492 💬 | 
Rosuvastatin | 006 11件:  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 | 
| 24 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
HMGCR 1件: HMGCR 💬 | 
D00434 D00434 💬 | 
Simvastatin | 006 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 | 
| 25 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
NR1H4 1件: NR1H4 💬 | 
D00163 D00163 💬 | 
Chenodeoxycholic acid | 020 4件: 20, 96, 234, 263 💬 | 
| 26 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
NR1H4 1件: NR1H4 💬 | 
D10699 D10699 💬 | 
Cholic Acid | 020 4件: 20, 234, 265, 310 💬 | 
| 27 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
NR1H4 1件: NR1H4 💬 | 
D09360 D09360 💬 | 
Obeticholic acid | 093 3件: 93, 265, 296 💬 | 
| 28 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
NR1H4 1件: NR1H4 💬 | 
D11548 D11548 💬 | 
Tropifexor | 093 1件: 93 💬 | 
| 29 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
NR1H4 1件: NR1H4 💬 | 
D00734 D00734 💬 | 
Ursodeoxycholic acid | 006 14件:  6 ,  8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 | 
| 30 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
RXRA 1件: RXRA 💬 | 
D02754 D02754 💬 | 
Acitretin | 037 1件: 37 💬 | 
| 31 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
RXRA 1件: RXRA 💬 | 
D02815 D02815 💬 | 
Alitretinoin | 049 1件: 49 💬 | 
| 32 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
RXRA 1件: RXRA 💬 | 
D03106 D03106 💬 | 
Bexarotene | 013 2件: 13, 75 💬 | 
| 33 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
SLC10A1 2件: SLC10A1, SLC10A2 💬 | 
D10951 D10951 💬 | 
Maralixibat | 296 3件: 296, 297, 338 💬 | 
| 34 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
SLC10A2 1件: SLC10A2 💬 | 
D10796 D10796 💬 | 
Elobixibat | 006 1件:  6  💬 | 
| 35 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare  | 
SLC10A2 1件: SLC10A2 💬 | 
D11716 D11716 💬 | 
Odevixibat | 296 3件: 296, 297, 338 💬 |