17. 多系統萎縮症 Multiple system atrophy Clinical trials / Disease details
臨床試験数 : 118 / 薬物数 : 163 - (DrugBank : 49) / 標的遺伝子数 : 61 - 標的パスウェイ数 : 112
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04616456 (ClinicalTrials.gov) | December 30, 2020 | 26/10/2020 | Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients | Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients | Multiple System Atrophy;Multiple System Atrophy, Cerebellar Variant;Multiple System Atrophy, Parkinson Variant (Disorder);Multiple System Atrophy (MSA) With Orthostatic Hypotension | Drug: [F-18]PBR06;Drug: Verdiperstat | Brigham and Women's Hospital | Biohaven Pharmaceuticals, Inc. | Active, not recruiting | 18 Years | N/A | All | 25 | Early Phase 1 | United States |
| 2 | EUCTR2019-001100-38-IT (EUCTR) | 19/02/2020 | 26/01/2021 | A study to assess whether a drug called BHV-3241 works and is safe to use in people with Multiple System Atrophy (M-STAR Study) | Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of BHV-3241 in Subjects with Multiple System Atrophy (M-STAR Study) - M-STAR Study | Multiple System Atrophy MedDRA version: 21.1;Level: PT;Classification code 10064060;Term: Multiple system atrophy;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Product Name: BHV-3241 Product Code: [/] INN or Proposed INN: Verdiperstat | Biohaven Pharmaceuticals, Inc. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 252 | Phase 3 | France;United States;Austria;Germany;United Kingdom;China;Italy | ||
| 3 | EUCTR2019-001100-38-DE (EUCTR) | 07/01/2020 | 07/10/2019 | A study to assess whether a drug called BHV-3241 works and is safe to use in people with Multiple System Atrophy (M-STAR Study) | Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of BHV-3241 in Subjects with Multiple System Atrophy (M-STAR Study) | Multiple System Atrophy MedDRA version: 21.1;Level: PT;Classification code 10064060;Term: Multiple system atrophy;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Product Name: BHV-3241 INN or Proposed INN: Verdiperstat | Biohaven Pharmaceuticals, Inc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 422 | Phase 3 | United States;France;Austria;Germany;United Kingdom;Italy;China | ||
| 4 | EUCTR2019-001100-38-AT (EUCTR) | 20/12/2019 | 29/10/2019 | A study to assess whether a drug called BHV-3241 works and is safe to use in people with Multiple System Atrophy (M-STAR Study) | Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of BHV-3241 in Subjects with Multiple System Atrophy (M-STAR Study) | Multiple System Atrophy MedDRA version: 21.1;Level: PT;Classification code 10064060;Term: Multiple system atrophy;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Product Name: BHV-3241 INN or Proposed INN: Verdiperstat | Biohaven Pharmaceuticals, Inc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 422 | Phase 3 | United States;France;Austria;Germany;United Kingdom;Italy;China | ||
| 5 | EUCTR2019-001100-38-FR (EUCTR) | 13/12/2019 | 03/10/2019 | A study to assess whether a drug called BHV-3241 works and is safe to use in people with Multiple System Atrophy(M-STAR Study) | Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of BHV-3241 in Subjects with Multiple System Atrophy (M-STAR Study) | Multiple System Atrophy MedDRA version: 21.1;Level: PT;Classification code 10064060;Term: Multiple system atrophy;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Product Name: BHV-3241 INN or Proposed INN: Verdiperstat | Biohaven Pharmaceuticals, Inc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 252 | Phase 3 | United States;France;Austria;Germany;Italy;United Kingdom | ||
| 6 | EUCTR2019-001100-38-GB (EUCTR) | 06/12/2019 | 11/10/2019 | A study to assess whether a drug called BHV-3241 works and is safe to use in people with Multiple System Atrophy(M-STAR Study) | Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of BHV-3241 in Subjects with Multiple System Atrophy (M-STAR Study) | Multiple System Atrophy MedDRA version: 21.1;Level: PT;Classification code 10064060;Term: Multiple system atrophy;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Product Name: BHV-3241 INN or Proposed INN: Verdiperstat | Biohaven Pharmaceuticals, Inc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 422 | Phase 3 | United States;France;Austria;Germany;Italy;United Kingdom | ||
| 7 | NCT03952806 (ClinicalTrials.gov) | July 29, 2019 | 15/5/2019 | Study of BHV-3241 in Subjects With Multiple System Atrophy | A Randomized, Double-Blind, Placebo-Controlled, Parallel- Group Study to Evaluate the Efficacy and Safety of BHV-3241 in Subjects With Multiple System Atrophy (M-STAR Study) | Multiple System Atrophy | Drug: Verdiperstat;Drug: Placebo | Biohaven Pharmaceuticals, Inc. | NULL | Active, not recruiting | 40 Years | 80 Years | All | 336 | Phase 3 | United States;Austria;France;Germany;Italy;United Kingdom |