218. アルポート症候群 Alport syndrome Clinical trials / Disease details
臨床試験数 : 26 / 薬物数 : 33 - (DrugBank : 13) / 標的遺伝子数 : 6 - 標的パスウェイ数 : 29
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05133050 (ClinicalTrials.gov) | January 1, 2022 | 27/10/2021 | Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 Variants | Safety and Efficacy of Early Angiotensin-converting Enzyme Inhibition in Patients With Alport Syndrome Carrying Pathogenic Heterozygous COL4A3,COL4A4 or COL4A5 Mutations | Alport Syndrome | Drug: Ramipril | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | NULL | Not yet recruiting | 30 Years | 50 Years | All | 510 | N/A | China |
| 2 | NCT01485978 (ClinicalTrials.gov) | March 2012 | 2/12/2011 | Efficacy and Safety Study to Delay Renal Failure in Children With Alport Syndrome | Early Prospective Therapy Trial to Delay Renal Failure in Children With Alport Syndrome | Renal Insufficiency, Chronic | Drug: Ramipril;Drug: placebo to ramipril | Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH | University Medical Center Goettingen;German Federal Ministry of Education and Research | Completed | 24 Months | 18 Years | All | 66 | Phase 3 | Germany |
| 3 | EUCTR2010-024300-10-DE (EUCTR) | 27/02/2012 | 12/12/2011 | Early prospective therapy trial to delay renal failure in children with Alport syndrome. - EARLY PRO-TECT Alport | Early prospective therapy trial to delay renal failure in children with Alport syndrome. - EARLY PRO-TECT Alport | Alport's syndrome MedDRA version: 19.1;Level: PT;Classification code 10001843;Term: Alport's syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] | Trade Name: Delix Product Name: Delix Other descriptive name: RAMIPRIL | University Medical Center Göttingen | NULL | Not Recruiting | Female: yes Male: yes | 120 | Phase 3 | Germany |