PRUCALOPRIDE ( DrugBank: Prucalopride )

3 diseases

13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-023996-25-BE (EUCTR)	21/12/2010	25/11/2010	The effect of fluoxetine and 5-HT4 serotonin receptor agonists on cerebral axonal energy metabolism and glutamate levels in multiple sclerosis.	The effect of fluoxetine and 5-HT4 serotonin receptor agonists on cerebral axonal energy metabolism and glutamate levels in multiple sclerosis.	Multiple sclerosis (both relapsing remitting and progressive forms)	Product Name: fluoxetine Other descriptive name: FLUOXETINE Product Name: Cisapride INN or Proposed INN: CISAPRIDE Product Name: Prucalopride INN or Proposed INN: PRUCALOPRIDE		NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	32		Belgium

臨床試験数 : 523 / 薬物数 : 608 - (DrugBank : 156) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 215

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2012-005348-92-IT (EUCTR)	19/02/2013	11/01/2013	PROGASS PRucalopride On the GAstreonteric transit in Systemic Sclerosis	PROGASS PRucalopride On the GAstreonteric transit in Systemic Sclerosis - PROGASS	Sysemic sclerosis with gastroenteric involvement (constipation) MedDRA version: 14.1;Level: SOC;Classification code 10017947;Term: Gastrointestinal disorders;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: RESOLOR*28CPR RIV 2MG INN or Proposed INN: PRUCALOPRIDE SUCCINATE	FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: no			Italy

臨床試験数 : 2,400 / 薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02806206 (ClinicalTrials.gov)	July 2016	15/6/2016	Prucalopride Prior to Small Bowel Capsule Endoscopy	The Effect of Prucalopride on Small Bowel Transit Time in Patients Undergoing Capsule Endoscopy: A Randomized Controlled Trial	Gastrointestinal Hemorrhage;Crohn Disease;Celiac Disease;Intestinal Diseases;Inflammatory Bowel Diseases	Drug: Prucalopride;Drug: Placebo	University of British Columbia	NULL	Not yet recruiting	19 Years	N/A	Both	122	Phase 4	Canada