Infliximab, etanercept ( DrugBank: Etanercept, Infliximab )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
46	悪性関節リウマチ	3

46. 悪性関節リウマチ

臨床試験数 : 4,325 / 薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000013750	2011/07/31	21/04/2014	Study on effects of cytokine targeted therapy on periodontal condition in patients with rheumatoid arthritis		Rheumatoid arthritis, Periodontitis	IL-6 receptor inhibition group: Tocilizumab will be infused in 20 patients, and its effectiveness will be evaluated at 3 and 6 months later. TNF inhibition group: Infliximab, Etanercept, and Adalimumab will be infused in 20 patients, and its effectiveness will be evaluated at 3 and 6 months later.	Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences	NULL	Complete: follow-up complete	Not applicable	Not applicable	Male and Female	80	Not selected	Japan
2	NCT01000441 (ClinicalTrials.gov)	December 23, 2009	22/10/2009	Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis	Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: infliximab, etanercept, adalimumab;Drug: abatacept, rituximab or tocilizumab	University Hospital, Strasbourg, France	NULL	Completed	18 Years	N/A	All	300	Phase 4	France;Monaco
3	NCT00317538 (ClinicalTrials.gov)	June 2003	21/4/2006	Open-label, Pilot Protocol of Patients With Rheumatoid Arthritis Who Switch to Infliximab After Incomplete Response to Etanercept	Open-label, Pilot Protocol of Patients With Rheumatoid Arthritis Who Switch to Infliximab After Incomplete Response to Etanercept	Rheumatoid Arthritis	Drug: infliximab, etanercept	Centocor Ortho Biotech Services, L.L.C.	NULL	Completed	18 Years	N/A	Both	28	Phase 3	NULL