Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1150-mg IVACAFTOR1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
2150mg IVACAFTOR1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
375-mg IVACAFTOR1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
4CF patients with a G551D mutation and treated with Ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
5Deuterated Ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
6Elexacaftor / Ivacaftor / Tezacaftor3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
7Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
8Elexacaftor-tezacaftor-ivacaftor exposure3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
9Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
10IVACAFTOR1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
11Ivacaftor (proposed INN)1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
12Ivacaftor 125mg tablet1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
13Ivacaftor 150 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
14Ivacaftor 150 mg or 250 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
15Ivacaftor 25 mg/75 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
16IVACAFTOR 59,5mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
17IVACAFTOR 59.5mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
18Ivacaftor 75 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
19Ivacaftor 75 mg/150 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
20IVACAFTOR 75mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
21Ivacaftor Exposed1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
22Ivacaftor or elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
23Ivacaftor+lumacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
24Ivacaftor/Ataluren2件: Ataluren,
Ivacaftor (Ivacaftorum)		2件: Ataluren ,
Ivacaftor (Ivacaftor) 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
25Ivacaftor/Kalydeco1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
26Ivacaftor/Trikafta3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
27Lumacaftor / ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
28Lumacaftor plus Ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
29Lumacaftor Plus Ivacaftor Combination2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
30Lumacaftor, Ivacaftor Drug Combination2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
31Lumacaftor-ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
32Lumacaftor-Ivacaftor treatment2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
33Lumacaftor/Ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
34Lumacaftor/ivacaftor 100mg/125mg tablets2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
35Lumacaftor/ivacaftor 200mg/125mg2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
36Lumacaftor/ivacaftor 200mg/125mg tablets2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
37Lumacaftor/ivacaftor 200mg/83mg tablet2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
38Orkambi: contains lumacaftor and ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
39Tezacaftor/Ivacaftor2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
40Tezacaftor/Ivacaftor + Ivacaftor2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
41Tezacaftor/Ivacaftor 100mg/150mg2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
42Tezacaftor/Ivacaftor/100mg/150mg2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
43Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor4件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Lumacaftor,
Tezacaftor		4件: Ivacaftor (Ivacaftor),
Lumacaftor ,
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
44VX-659/Tezacaftor/Ivacaftor3件: Ivacaftor (Ivacaftorum),
Tezacaftor,
VX-659		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
45VX-661 Plus Ivacaftor Combination1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
46VX-661/Ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
47VX-661/ivacaftor (VX-770) 100mg/150 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
48VX-661/ivacaftor 100 mg/ 150 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
49VX-661/ivacaftor 100mg/150 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
50VX-661/ivacaftor 100mg/150mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
51VX-661/ivacaftor 50 mg/ 75 mg1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬