Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Metformin
(Repaglinide and Metformin Hydrochloride)		5件: Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine1件: Metformin 💬 2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
2 Pioglitazone
(Pioglitazone Hydrochloride and Metformin Hydrochloride)		1件: Pioglitazone1件: Pioglitazone 💬 1件: PPARG 💬 11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
3 Repaglinide
(Repaglinide and Metformin Hydrochloride)		1件: Repaglinide1件: Repaglinide 💬 2件: ABCC8,
KCNJ11 💬 		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬4件: 6, 21, 46, 299 💬
4 Sitagliptin
(Sitagliptin Phosphate/Metformin Hydrochloride)		1件: Sitagliptin1件: Sitagliptin 💬 1件: DPP4 💬 1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299 💬