Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 💬1件: Abatacept2件: ABATACEPT; ORENCIA2件: CD80,
CD86 💬 		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen 💬1件: Acetaminophen4件: Acetaminophen; Paracetamol; Tylenol; Ultracet2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Acetylcysteine 💬1件: Acetylcysteine3件: ACETYLCYSTEINE; Mucomyst; N-acetylcysteine--21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
4 Afimetoran 💬1件: Afimetoran2件: Afimetoran; BMS-986256--1件: 49 💬
5 Albuterol 💬1件: Salbutamol3件: Albuterol; Salbutamol; Ventolin1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
6 Aldesleukin 💬1件: Aldesleukin4件: ALDESLEUKIN; ILT-101; Proleukin; Recombinant human interleukin-23件: IL2RA,
IL2RB,
IL2RG 💬 		14件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬6件: 2, 35, 49, 65, 96, 97 💬
7 Alemtuzumab 💬1件: Alemtuzumab4件: Alemtuzumab; Campath; Lemtrada; MABCAMPATH1件: CD52 💬 1件: 💬22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
8 Alfacalcidol 💬1件: Alfacalcidol2件: Alfacalcidol; One-alpha1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
9 Alitretinoin 💬1件: Alitretinoin2件: ALITRETINOIN; Toctino5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬 		19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 49 💬
10 Aminohippuric acid 💬1件: Aminohippuric acid1件: Aminohippurate--1件: 67 💬
11 Anakinra 💬1件: Anakinra2件: Anakinra; Kineret2件: IL1R1,
IL1R2 💬 		15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬18件: 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
12 Anifrolumab 💬1件: Anifrolumab1件: ANIFROLUMAB2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬3件: 46, 49, 53 💬
13 Artenimol 💬1件: Artenimol1件: Dihydroartemisinin--1件: 49 💬
14 Aspirin 💬1件: Acetylsalicylic acid2件: Acetylsalicylic acid; Aspirin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
15 Atacicept 💬1件: Atacicept2件: ATACICEPT; TACI-Fc52件: TNFSF13,
TNFSF13B 💬 		4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬4件: 13, 46, 49, 66 💬
16 Atorvastatin 💬1件: Atorvastatin3件: Atorvastatin; Atorvastatin calcium; Lipitor1件: HMGCR 💬 4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
17 Aviptadil 💬1件: Aviptadil1件: AVIPTADIL--5件: 49, 51, 84, 85, 86 💬
18 Azathioprine 💬1件: Azathioprine3件: Azathioprine; AZATIOPRINA; Imuran--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
19 Baricitinib 💬1件: Baricitinib2件: Baricitinib; Olumiant2件: JAK1,
JAK2 💬 		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
20 Belimumab 💬1件: Belimumab2件: BELIMUMAB; BENLYSTA1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
21 Benazepril 💬1件: Benazepril1件: Benazepril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 49, 57, 218, 224 💬
22 Blisibimod 💬1件: Blisibimod1件: Blisibimod--5件: 43, 44, 49, 63, 66 💬
23 Bortezomib 💬1件: Bortezomib3件: Bortezomib; Bortezomib Accord; Velcade1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
24 Branebrutinib 💬1件: Branebrutinib2件: BMS-986195; Branebrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬3件: 46, 49, 53 💬
25 Brentuximab vedotin 💬1件: Brentuximab vedotin2件: Brentuximab; Brentuximab Vedotin10件: TNFRSF8,
TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬 		11件: Alzheimer disease, Amyotrophic lateral sclerosis, Cytokine-cytokine receptor interaction, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬2件: 49, 51 💬
26 Busulfan 💬1件: Busulfan3件: Busilvex; Busulfan; BUSULFANO--13件: 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
27 Calcitriol 💬1件: Calcitriol1件: Calcitriol1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
28 Cenerimod 💬1件: Cenerimod1件: Cenerimod1件: S1PR1 💬 3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬1件: 49 💬
29 Certolizumab pegol 💬1件: Certolizumab pegol2件: Certolizumab pegol; Cimzia1件: TNF 💬 67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
30 Chloroquine 💬1件: Chloroquine1件: Chloroquine--3件: 46, 49, 95 💬
31 Cholecalciferol 💬1件: Cholecalciferol5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬16件: 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
32 Clopidogrel 💬1件: Clopidogrel1件: Clopidogrel1件: P2RY12 💬 1件: Platelet activation 💬3件: 49, 51, 86 💬
33 Clopidogrel besilate 💬1件: Clopidogrel1件: Clopidogrel1件: P2RY12 💬 1件: Platelet activation 💬3件: 49, 51, 86 💬
34 Clopidogrel hydrochloride 💬1件: Clopidogrel1件: Clopidogrel1件: P2RY12 💬 1件: Platelet activation 💬3件: 49, 51, 86 💬
35 Corticotropin 💬1件: Corticotropin5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin1件: MC2R 💬 5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
36 Cyclophosphamide 💬1件: Cyclophosphamide6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
37 Cyclophosphamide 💬1件: Cyclophosphamide6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
38 Cyclosporine 💬1件: Cyclosporine10件: CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; RESTASIS5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
39 Cytarabine 💬1件: Cytarabine1件: Cytarabine--7件: 11, 13, 14, 25, 49, 60, 65 💬
40 Dapagliflozin 💬1件: Dapagliflozin2件: Dapagliflozin; Forxiga1件: SLC5A2 💬 1件: 💬7件: 19, 49, 66, 67, 86, 88, 222 💬
41 Daratumumab 💬1件: Daratumumab2件: Daratumumab; Darzalex1件: CD38 💬 7件: Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬5件: 13, 28, 48, 49, 63 💬
42 Daxdilimab 💬1件: Daxdilimab1件: Daxdilimab1件: LILRA4 💬 2件: B cell receptor signaling pathway, Osteoclast differentiation 💬2件: 49, 50 💬
43 Deucravacitinib 💬1件: Deucravacitinib1件: Deucravacitinib1件: TYK2 💬 16件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis 💬3件: 49, 96, 97 💬
44 Dexchlorpheniramine 💬1件: Dexchlorpheniramine1件: Dexchlorpheniramine1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 49 💬
45 Dimethyl fumarate 💬1件: Dimethyl fumarate3件: Dimethyl fumarate; Dimethylfumarat; TECFIDERA1件: KEAP1 💬 6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 49, 51, 86, 296 💬
46 Diphenhydramine 💬1件: Diphenhydramine2件: Diphenhydramine; Diphenhydramine hydrochloride1件: HRH1 💬 3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256 💬
47 Dipyridamole 💬1件: Dipyridamole1件: Dipyridamole2件: PDE4A,
PDE5A 💬 		6件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 46, 49, 51, 66, 96, 224 💬
48 Edratide 💬1件: Edratide1件: Edratide--1件: 49 💬
49 Efalizumab 💬1件: Efalizumab2件: EFALIZUMAB; Raptiva1件: ITGAL 💬 12件: Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
50 Efavaleukin alfa 💬1件: Efavaleukin alfa1件: EFAVALEUKIN ALFA--2件: 49, 97 💬
51 Emapalumab 💬1件: Emapalumab1件: EMAPALUMAB1件: IFNG 💬 32件: African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬3件: 49, 65, 107 💬
52 Epratuzumab 💬1件: Epratuzumab1件: EPRATUZUMAB1件: CD22 💬 3件: B cell receptor signaling pathway, Cell adhesion molecules, Hematopoietic cell lineage 💬1件: 49 💬
53 Ergocalciferol 💬1件: Ergocalciferol3件: Ergocalciferol; Vitamin D; Vitamin D21件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬6件: 46, 49, 84, 96, 97, 299 💬
54 Estradiol 💬1件: Estradiol1件: Estradiol2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬7件: 13, 46, 49, 65, 76, 226, 299 💬
55 Estrogens, conjugated 💬1件: Conjugated estrogens1件: Conjugated equine estrogens--1件: 49 💬
56 Ethinyl estradiol 💬1件: Ethinylestradiol3件: Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 7771件: ESR1 💬 9件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 13, 46, 49, 299 💬
57 Evobrutinib 💬1件: Evobrutinib1件: Evobrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬3件: 13, 46, 49 💬
58 Ezetimibe 💬1件: Ezetimibe2件: Ezetimibe; Ezetrol1件: NPC1L1 💬 1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260 💬
59 Filgrastim 💬1件: Filgrastim7件: Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; NEUPOGEN; TEVAGRASTIM; ZARZIO1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
60 Fludarabine 💬1件: Fludarabine4件: FLUDARA; Fludarabina; Fludarabine; FLUDARABINE PHOSPHATE1件: RRM1 💬 6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
61 Folic acid 💬1件: Folic acid5件: Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE--6件: 6, 41, 46, 49, 84, 296 💬
62 Forigerimod 💬1件: Forigerimod1件: Forigerimod--1件: 49 💬
63 Fostamatinib 💬1件: Fostamatinib1件: Fostamatinib1件: SYK 💬 17件: B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬4件: 46, 49, 61, 66 💬
64 Fulvestrant 💬1件: Fulvestrant2件: Faslodex; Fulvestrant2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 49, 86 💬
65 Fumaric acid 💬1件: Fumaric acid1件: Fumaric acid--1件: 13 💬
66 Glucose 💬1件: D-glucose2件: D-glucose; Glucose--3件: 49, 86, 88 💬
67 Hydroxychloroquine 💬1件: Hydroxychloroquine3件: Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil--27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
68 Ianalumab 💬1件: Ianalumab1件: Ianalumab1件: TNFRSF13C 💬 5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬7件: 35, 46, 49, 53, 61, 63, 95 💬
69 Icosapent 💬1件: Icosapent2件: Eicosapentaenoic acid; Icosapent--7件: 8, 49, 96, 97, 296, 297, 338 💬
70 Infliximab 💬1件: Infliximab6件: Flixabi; INFLECTRA; INFLIXIMAB; Remicade; REMSIMA; Zessly1件: TNF 💬 67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
71 Iscalimab 💬1件: Iscalimab1件: ISCALIMAB1件: CD40 💬 17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬2件: 49, 53 💬
72 Itolizumab 💬1件: Itolizumab1件: Itolizumab1件: CD6 💬 1件: Cell adhesion molecules 💬1件: 49 💬
73 Lactobacillus casei 💬1件: Lactobacillus casei2件: Fusion; Lactobacillus casei--10件: 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
74 Lactomin 💬1件: Lactobacillus acidophilus4件: Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus--3件: 6, 49, 97 💬
75 Leflunomide 💬1件: Leflunomide3件: ARAVA; Leflunomide; Leflunomidum1件: DHODH 💬 3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
76 Lenalidomide 💬1件: Lenalidomide2件: Lenalidomide; REVLIMID1件: TNF 💬 67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
77 Levosalbutamol 💬1件: Levosalbutamol2件: R-salbutamol; Salbutamol1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 49 💬
78 Levothyroxine 💬1件: Levothyroxine2件: Levothyroxine; Thyroxine2件: THRA,
THRB 💬 		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬4件: 19, 49, 78, 80 💬
79 Lisinopril 💬1件: Lisinopril2件: Lisinopril; Zestril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
80 Lisinopril 💬1件: Lisinopril2件: Lisinopril; ZESTRIL1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222 💬
81 Medroxyprogesterone acetate 💬1件: Medroxyprogesterone acetate1件: Medroxyprogesterone1件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 49 💬
82 Melatonin 💬1件: Melatonin2件: Circadin; Melatonin2件: MTNR1A,
MTNR1B 💬 		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬12件: 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
83 Meloxicam 💬1件: Meloxicam1件: Meloxicam1件: PTGS2 💬 22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 46, 49, 271, 296 💬
84 Memantine 💬1件: Memantine3件: EBIXA; Memantine; MEMANTINE HYDROCHLORIDE5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
85 Mestranol 💬1件: Mestranol1件: Ortho-novum2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 46, 49 💬
86 Metformin 💬1件: Metformin5件: Metformin; Metformin HCl; Metformin Hydrochloride; Metformina; Metformine2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
87 Methotrexate 💬1件: Methotrexate6件: Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate2件: DHFR,
DHFR2 💬 		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
88 Methylprednisolone 💬1件: Methylprednisolone4件: Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
89 Methylprednisolone hemisuccinate 💬1件: Methylprednisolone hemisuccinate4件: Methylprednisolone hemisuccinate; METHYLPREDNISOLONE SODIUM SUCCINATE; Methylprednisolone succinate; SOLU-MEDROL1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬7件: 13, 49, 50, 51, 53, 97, 211 💬
90 Milatuzumab 💬1件: Milatuzumab1件: Milatuzumab1件: CD74 💬 3件: Antigen processing and presentation, Herpes simplex virus 1 infection, Tuberculosis 💬1件: 49 💬
91 Milnacipran 💬1件: Milnacipran1件: Milnacipran2件: SLC6A2,
SLC6A4 💬 		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 46, 49 💬
92 Mizoribine 💬1件: Mizoribine2件: BREDININ; Mizoribine2件: IMPDH1,
IMPDH2 💬 		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
93 Modafinil 💬1件: Modafinil2件: Modafinil; Provigil--5件: 6, 13, 49, 93, 113 💬
94 Monomethyl fumarate 💬1件: Monomethyl fumarate2件: Bafiertam; Monomethyl fumarate--1件: 13 💬
95 Mosunetuzumab 💬1件: Mosunetuzumab1件: Mosunetuzumab2件: CD3E,
MS4A1 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 49 💬
96 Moxifloxacin 💬1件: Moxifloxacin2件: Moxifloxacin; Moxifloxacin Hydrochloride--9件: 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
97 Mycophenolate mofetil 💬1件: Mycophenolate mofetil3件: CELLCEPT; Mycophenolate Mofetil; Mycophenolate mofetil TEVA2件: IMPDH1,
IMPDH2 💬 		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
98 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic Acid; Myfortic2件: IMPDH1,
IMPDH2 💬 		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
99 Nelfinavir 💬1件: Nelfinavir1件: Nelfinavir--3件: 49, 265, 331 💬
100 Niacinamide 💬1件: Nicotinamide3件: Multivitamin; Niacinamide; Nicotinamide--10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
101 Nipocalimab 💬1件: Nipocalimab1件: Nipocalimab1件: FCGRT 💬 1件: 💬6件: 11, 14, 46, 49, 53, 61 💬
102 Nivolumab 💬1件: Nivolumab1件: Nivolumab1件: PDCD1 💬 3件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
103 Norethindrone 💬1件: Norethisterone3件: Norethindrone; Ortho-novum; Ortho-Novum 7771件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬4件: 13, 46, 49, 299 💬
104 Obinutuzumab 💬1件: Obinutuzumab2件: Gazyvaro; Obinutuzumab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬4件: 43, 44, 49, 222 💬
105 Ocrelizumab 💬1件: Ocrelizumab3件: Ocrelizumab; OCREVUS; RhuMAb 2H71件: MS4A1 💬 1件: Hematopoietic cell lineage 💬3件: 13, 46, 49 💬
106 Olive oil 💬1件: Olive oil1件: Olive oil--5件: 13, 35, 49, 53, 162 💬
107 Orelabrutinib 💬1件: Orelabrutinib1件: Orelabrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬4件: 13, 49, 61, 63 💬
108 Oxygen 💬1件: Oxygen3件: Medical air; Nitrogen; Oxygen--13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330 💬
109 Pioglitazone 💬1件: Pioglitazone1件: Pioglitazone1件: PPARG 💬 11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
110 Prasterone 💬1件: Prasterone3件: Dehydroepiandrosterone; DHEA; Prasterone3件: AR,
ESR1,
ESR2 💬 		12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬6件: 49, 53, 83, 86, 96, 113 💬
111 Pravastatin 💬1件: Pravastatin2件: Pravastatin; Pravastatin sodium1件: HMGCR 💬 4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
112 Prednisolone 💬1件: Prednisolone3件: Prednisolona; PREDNISOLONE; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
113 Prednisone 💬1件: Prednisone3件: PREDNISONA; Prednisone; RAYOS1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
114 Prednisone acetate 💬1件: Prednisone acetate2件: Cortancyl; Prednisone acetate1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬6件: 35, 41, 46, 49, 162, 224 💬
115 Ramipril 💬1件: Ramipril1件: Ramipril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257 💬
116 Rituximab 💬1件: Rituximab6件: MabThera; Rituxan; Rituximab; Rixathon; Ruxience; Truxima1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
117 Rivaroxaban 💬1件: Rivaroxaban2件: RIVAROXABAN; Xarelto1件: F10 💬 1件: Complement and coagulation cascades 💬4件: 46, 49, 91, 210 💬
118 Rontalizumab 💬1件: Rontalizumab1件: Rontalizumab13件: IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬 		25件: Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 49 💬
119 Rosuvastatin 💬1件: Rosuvastatin3件: Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM1件: HMGCR 💬 4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
120 Royal jelly 💬1件: Royal jelly1件: Royal jelly--1件: 49 💬
121 Sifalimumab 💬1件: Sifalimumab1件: Sifalimumab13件: IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬 		25件: Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 49 💬
122 Simvastatin 💬1件: Simvastatin3件: SIMVASTATIN; Simvastatina; Simvastatine1件: HMGCR 💬 4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
123 Sirolimus 💬1件: Sirolimus3件: RAPAMUNE; Rapamycin; Sirolimus1件: MTOR 💬 51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
124 Sulfamethoxazole 💬1件: Sulfamethoxazole3件: Bactrim; SULFAMETHOXAZOLE; Sulphamethoxazole--5件: 44, 49, 61, 85, 299 💬
125 Tabalumab 💬1件: Tabalumab1件: TABALUMAB1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬2件: 46, 49 💬
126 Tacrolimus 💬1件: Tacrolimus2件: Prograf; Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
127 Tacrolimus 💬1件: Tacrolimus2件: Prograf; Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
128 Thalidomide 💬1件: Thalidomide1件: THALIDOMIDE1件: TNF 💬 67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
129 Tocilizumab 💬1件: Tocilizumab3件: ACTEMRA; RoActemra; TOCILIZUMAB1件: IL6R 💬 12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
130 Tocopherol 💬1件: Tocopherol2件: Tocoferol; TOCOPHEROL--6件: 13, 49, 90, 206, 257, 298 💬
131 Tofacitinib 💬1件: Tofacitinib4件: Tasocitinib; Tofacitinib; XELJANZ; Xeljanz XR4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
132 Trimethoprim 💬1件: Trimethoprim2件: Bactrim; Trimethoprim--7件: 36, 44, 49, 60, 61, 85, 299 💬
133 Triptorelin 💬1件: Triptorelin2件: GnRH; TRIPTORELIN1件: GNRHR 💬 2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬2件: 49, 76 💬
134 Upadacitinib 💬1件: Upadacitinib2件: Rinvoq; Upadacitinib1件: JAK1 💬 27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
135 Ustekinumab 💬1件: Ustekinumab2件: STELARA; Ustekinumab3件: IL12A,
IL12B,
IL23A 💬 		28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
136 Vitamin E 💬1件: Vitamin E2件: Alpha-tocopherol; Vitamin E--12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
137 Vobarilizumab 💬1件: Vobarilizumab1件: Vobarilizumab--1件: 49 💬
138 Voclosporin 💬1件: Voclosporin1件: Voclosporin5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 49, 222 💬
139 Warfarin 💬1件: Warfarin2件: Warfarin; Warfarin Sodium2件: NQO1,
VKORC1 💬 		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬