Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D01977	Gefitinib	1件: 75
2	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D03455	Cetuximab	2件: 51, 86
3	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D07907	Erlotinib	1件: 94
4	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D08108	Lapatinib	3件: 34, 74, 75
5	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D08950	Neratinib	1件: 34
6	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D11251	Icotinib	1件: 34
7	EGFR	40件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D11772	Tesevatinib	1件: 67
8	MTOR	38件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D00753	Sirolimus	40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, ...
9	MTOR	38件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D02714	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
10	MTOR	38件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D06068	Temsirolimus	1件: 13

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