Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CDK4	4件: Tight junction, T cell receptor signaling pathway, Viral carcinogenesis, Small cell lung cancer	D10688	Abemaciclib	1件: 34
2	CDK6	2件: Viral carcinogenesis, Small cell lung cancer	D10688	Abemaciclib	1件: 34
3	NFKB1	12件: Sphingolipid signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differen ...	D01146	Iguratimod	5件: 46, 51, 53, 271, 300
4	PIK3CA	11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T ...	D11011	Alpelisib	1件: 138
5	PIK3CA	11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T ...	D11158	Leniolisib	2件: 53, 65
6	PIK3CB	11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T ...	D11158	Leniolisib	2件: 53, 65
7	PIK3CD	11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T ...	D11158	Leniolisib	2件: 53, 65
8	PIK3CD	11件: Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T ...	D11437	Parsaclisib	3件: 35, 53, 61
9	PTGS2	3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer	D00109	Acetylsalicylic acid	14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
10	PTGS2	3件: VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer	D00118	Naproxen	4件: 13, 46, 107, 271

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