Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
LEPR 1件: LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 1件: 265 💬
|
| 4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 6 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 7 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 8 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 9 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2A 1件: ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 10 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2A 1件: ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 11 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 12 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 13 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬
|
Atorvastatin Atorvastatin 💬
| Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
|
| 14 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬
|
Pravastatin Pravastatin 💬
| Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
|
| 15 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
| 16 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 17 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
LEPR 1件: LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 1件: 265 💬
|
| 18 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 19 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 20 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 21 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 22 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 23 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 24 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 25 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 26 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬
|
Atorvastatin Atorvastatin 💬
| Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
|
| 27 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬
|
Pravastatin Pravastatin 💬
| Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
|
| 28 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
| 29 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 1件: NR1H4 💬
|
Cholic acid Cholic acid 💬
| Cholic Acid | 020 4件: 20, 234, 265, 310 💬
|
| 30 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 1件: NR1H4 💬
|
Obeticholic acid Obeticholic acid 💬
| Obeticholic acid | 093 3件: 93, 265, 296 💬
|
| 31 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 32 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A 2件: ADORA2A, PDE1B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 33 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A 2件: ADORA2A, PDE1B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 34 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 35 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 36 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 37 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 38 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 39 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 40 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 41 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 42 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
APOC3 1件: APOC3 💬
|
Volanesorsen Volanesorsen 💬
| Volanesorsen | 265 1件: 265 💬
|
| 43 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 44 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 45 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 46 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR 1件: GHR 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 47 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR 1件: GHR 💬
|
Pegvisomant Pegvisomant 💬
| Pegvisomant | 078 2件: 78, 265 💬
|
| 48 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LEPR 1件: LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 1件: 265 💬
|
| 49 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 50 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 51 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 52 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 53 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 54 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 55 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 56 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 57 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 58 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 59 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 60 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 61 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 62 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 63 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 64 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
GHR 1件: GHR 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 65 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
GHR 1件: GHR 💬
|
Pegvisomant Pegvisomant 💬
| Pegvisomant | 078 2件: 78, 265 💬
|
| 66 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
GHRHR 1件: GHRHR 💬
|
Tesamorelin Tesamorelin 💬
| Tesamorelin | 078 2件: 78, 265 💬
|
| 67 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 68 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 69 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 70 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 71 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 72 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 73 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 74 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 75 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 76 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 77 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 78 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 79 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 80 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 81 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 82 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 83 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 84 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 85 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 86 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
GHR 1件: GHR 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 87 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
GHR 1件: GHR 💬
|
Pegvisomant Pegvisomant 💬
| Pegvisomant | 078 2件: 78, 265 💬
|
| 88 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 89 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
LEPR 1件: LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 1件: 265 💬
|
| 90 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 91 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 92 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 93 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 94 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 95 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 96 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 97 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 98 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 99 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 100 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 101 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 102 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 103 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 104 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 105 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬
|
Atorvastatin Atorvastatin 💬
| Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
|
| 106 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬
|
Pravastatin Pravastatin 💬
| Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
|
| 107 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬
|
Simvastatin Simvastatin 💬
| Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
|
| 108 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 109 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 110 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 111 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 112 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 113 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 114 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 115 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 2件: ADORA1, ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 116 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 2件: ADORA1, ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 117 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR 1件: GHR 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 118 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR 1件: GHR 💬
|
Pegvisomant Pegvisomant 💬
| Pegvisomant | 078 2件: 78, 265 💬
|
| 119 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHRHR 1件: GHRHR 💬
|
Tesamorelin Tesamorelin 💬
| Tesamorelin | 078 2件: 78, 265 💬
|
| 120 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
LEPR 1件: LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 1件: 265 💬
|
| 121 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC4R 1件: MC4R 💬
|
Setmelanotide Setmelanotide 💬
| Setmelanotide | 202 2件: 202, 265 💬
|
| 122 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 123 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
LEPR 1件: LEPR 💬
|
Metreleptin Metreleptin 💬
| Metreleptin | 265 1件: 265 💬
|
| 124 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 125 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 126 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 127 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 128 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1B 2件: PDE1B, PDE2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 129 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1B 2件: PDE1B, PDE2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 130 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 131 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 132 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 133 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 134 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 135 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 136 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 137 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 138 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 139 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A 1件: ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 140 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A 1件: ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 141 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 142 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 143 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 144 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 145 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 146 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR 1件: GHR 💬
|
Pegvisomant Pegvisomant 💬
| Pegvisomant | 078 2件: 78, 265 💬
|
| 147 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR 2件: GHR, IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 148 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 149 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
| 150 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
APOC3 1件: APOC3 💬
|
Volanesorsen Volanesorsen 💬
| Volanesorsen | 265 1件: 265 💬
|
| 151 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA 1件: PPARA 💬
|
Fenofibrate Fenofibrate 💬
| Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬
|
| 152 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG 1件: PPARG 💬
|
Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
|
| 153 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG 1件: PPARG 💬
|
Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
|
| 154 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 155 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 156 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B 1件: PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 157 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 158 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 159 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 160 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 161 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 162 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2A 1件: ADORA2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 163 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2A 1件: ADORA2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 164 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 165 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 166 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 2件: ADORA1, PDE3B 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 167 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 2件: ADORA1, PDE3B 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 168 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬
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Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 169 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬
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Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 170 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R 1件: IGF1R 💬
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Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
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| 171 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
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| 172 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 1件: ADORA1 💬
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Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 173 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 1件: ADORA1 💬
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Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 174 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1B 1件: PDE1B 💬
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Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 175 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1B 1件: PDE1B 💬
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Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 176 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬
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Atorvastatin Atorvastatin 💬
| Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
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| 177 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬
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Pravastatin Pravastatin 💬
| Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
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| 178 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬
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Simvastatin Simvastatin 💬
| Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
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| 179 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
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| 180 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
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| 181 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬
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Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
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| 182 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬
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Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
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| 183 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
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| 184 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
PPARG 1件: PPARG 💬
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Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
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| 185 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
PPARG 1件: PPARG 💬
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Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
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| 186 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
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| 187 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
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| 188 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IGF1R 1件: IGF1R 💬
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Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
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| 189 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PPARG 1件: PPARG 💬
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Pioglitazone Pioglitazone 💬
| Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
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| 190 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PPARG 1件: PPARG 💬
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Rosiglitazone Rosiglitazone 💬
| Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬
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| 191 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
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| 192 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2A 1件: ADORA2A 💬
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Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 193 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2A 1件: ADORA2A 💬
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Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
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| 194 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 1件: JAK1 💬
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Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
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