Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 6 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 7 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 8 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 9 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 10 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 11 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 12 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 13 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 14 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 15 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 16 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 17 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 18 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 19 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 20 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 21 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 3件: IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 22 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 23 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 24 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 25 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
MC2R 1件: MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 26 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 27 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL10 2件: IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 28 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 29 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 30 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 31 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 32 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 33 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 34 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 35 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 36 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 37 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 38 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 39 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 40 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 41 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 42 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 43 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 44 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 45 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
CACNA1C 2件: CACNA1C, CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 46 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 47 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 48 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 49 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 50 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 51 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 52 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 53 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 54 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 55 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
| 56 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 57 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 3件: IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 58 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 59 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 60 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 61 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 62 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 63 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 64 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 65 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 66 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 67 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL10 2件: IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 68 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 69 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 70 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 71 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL10 1件: IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 72 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
TPO 1件: TPO 💬
|
Methimazole Methimazole 💬
| Methimazole | 050 1件: 50 💬
|
| 73 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 74 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 75 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 76 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
LILRA4 1件: LILRA4 💬
|
Daxdilimab Daxdilimab 💬
| Daxdilimab | 049 2件: 49, 50 💬
|
| 77 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 78 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 79 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 80 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
| 81 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
PGR 1件: PGR 💬
|
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬
| Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬
|
| 82 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 83 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 84 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 85 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 86 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 87 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 88 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 89 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 90 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 91 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 92 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 93 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 94 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 95 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 96 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MC2R 1件: MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 97 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬
|
| 98 | Carbohydrate digestion and absorption 💬 14 genes, 19 drugs (DrugBank) and 30 diseases |
CACNA1D 1件: CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 99 | Cardiac muscle contraction 💬 13 genes, 17 drugs (DrugBank) and 26 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 100 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 101 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
PDCD1 1件: PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
| 102 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
CACNA1D 1件: CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 103 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 104 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 105 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 106 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 107 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 108 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A 1件: PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
| 109 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 110 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 111 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 112 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 113 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 114 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 115 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 116 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 117 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 118 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 119 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 120 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR 1件: PGR 💬
|
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬
| Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬
|
| 121 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 122 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
| 123 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 1件: CCL2 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 124 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 125 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 2件: JAK2, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 126 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 127 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 128 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 129 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1C 2件: CACNA1C, CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 130 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 131 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 132 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 133 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 134 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 135 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 136 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 137 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 138 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 139 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 140 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 141 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
MC2R 1件: MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 142 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 143 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MC2R 1件: MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 144 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 6件: CCL2, IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 145 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 146 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 147 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 148 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 149 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 150 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 151 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 152 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 153 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 154 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 2件: IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 155 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 156 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 157 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 158 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 159 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
CACNA1C 2件: CACNA1C, CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 160 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 161 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 162 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 163 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 1件: IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 164 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 165 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 166 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 167 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
| 168 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 169 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 2件: IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 170 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 171 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 172 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 173 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 174 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
PGR 1件: PGR 💬
|
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬
| Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬
|
| 175 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 176 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 177 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 178 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 4件: CCL2, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 179 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 180 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 181 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 182 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 183 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
| 184 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL10 2件: IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 185 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
S1PR1 1件: S1PR1 💬
|
Siponimod Siponimod 💬
| Siponimod | 013 2件: 13, 50 💬
|
| 186 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 187 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 188 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 189 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 190 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
CACNA1C 2件: CACNA1C, CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 191 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 192 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 193 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 194 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 195 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 196 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 197 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 198 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 199 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 200 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 201 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 202 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 203 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 204 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 205 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 206 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 207 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 208 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 209 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 1件: MS4A1 💬
|
Rituximab Rituximab 💬
| Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
|
| 210 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 211 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 212 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 2件: IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 213 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 214 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 215 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 216 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 217 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 218 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 2件: JAK1, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 219 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 220 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 221 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 222 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 223 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 224 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 225 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 226 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 227 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 228 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 229 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 230 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 1件: IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 231 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 232 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 233 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 234 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 235 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 236 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 237 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 238 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 239 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 240 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 241 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 242 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 243 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 244 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 245 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 246 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 247 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 248 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 249 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 250 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 2件: JAK1, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 251 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 252 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 253 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 254 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
| 255 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
FDPS 1件: FDPS 💬
|
Risedronic acid Risedronic acid 💬
| Risedronic acid | 046 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
|
| 256 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 257 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 258 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 2件: IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 259 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 260 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 2件: JAK1, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 261 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 262 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 263 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 264 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 265 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 266 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 267 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 2件: IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 268 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 269 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 270 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 271 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 272 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 273 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 274 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 275 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 276 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 277 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 278 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 279 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 280 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 281 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 282 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 283 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
| 284 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
FDPS 1件: FDPS 💬
|
Risedronic acid Risedronic acid 💬
| Risedronic acid | 046 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
|
| 285 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 286 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 287 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 288 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 289 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 290 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 291 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 2件: IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 292 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 293 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 294 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 295 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 296 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL10 2件: IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 297 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL10 2件: IL10, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 298 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 299 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 300 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 301 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 302 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 303 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
CD86 1件: CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 304 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 1件: IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 305 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 306 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 307 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 308 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 309 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 310 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 311 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 312 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 3件: IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 313 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 314 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 315 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL10 4件: IL10, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 316 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 317 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 318 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 319 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 320 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 321 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 322 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 323 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 324 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 325 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 326 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 327 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 328 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 329 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 330 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 331 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 332 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
CACNA1C 1件: CACNA1C 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 333 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 334 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 335 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 336 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 337 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A 1件: IL12A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 338 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 339 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 340 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 341 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 342 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 343 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 344 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 345 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 346 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 347 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 348 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 349 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 350 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 351 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A 3件: IL1A, IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 352 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 353 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 354 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 355 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 356 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
| 357 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
| 358 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS 1件: FDPS 💬
|
Risedronic acid Risedronic acid 💬
| Risedronic acid | 046 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
|
| 359 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬
|
| 360 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A 1件: PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
| 361 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TPO 1件: TPO 💬
|
Methimazole Methimazole 💬
| Methimazole | 050 1件: 50 💬
|
| 362 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
| 363 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬
|
| 364 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 365 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 366 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 367 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 368 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 369 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 370 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 371 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 372 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 373 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 374 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 375 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 376 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 377 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 378 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 379 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 380 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR2 1件: CNR2 💬
|
Lenabasum Lenabasum 💬
| Ajulemic acid | 050 3件: 50, 51, 299 💬
|
| 381 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC2R 1件: MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
| 382 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Methylprednisolone Methylprednisolone 💬
| Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
|
| 383 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Methylprednisolone hemisuccinate Methylprednisolone hemisuccinate 💬
| Methylprednisolone hemisuccinate | 013 7件: 13, 49, 50, 51, 53, 97, 211 💬
|
| 384 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Prednisolone Prednisolone 💬
| Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
|
| 385 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Prednisone Prednisone 💬
| Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
|
| 386 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
S1PR1 2件: S1PR1, S1PR5 💬
|
Siponimod Siponimod 💬
| Siponimod | 013 2件: 13, 50 💬
|
| 387 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 388 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 389 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 2件: IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 390 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 391 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 392 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 393 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 394 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 395 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 396 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 397 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 2件: JAK1, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 398 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 399 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 400 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 401 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 402 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 403 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 404 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 405 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
JAK3 1件: JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 406 | One carbon pool by folate 💬 3 genes, 2 drugs (DrugBank) and 38 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
| 407 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PGR 1件: PGR 💬
|
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬
| Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬
|
| 408 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 409 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 410 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 411 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 412 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 413 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 414 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 415 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 416 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
LILRA4 1件: LILRA4 💬
|
Daxdilimab Daxdilimab 💬
| Daxdilimab | 049 2件: 49, 50 💬
|
| 417 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 418 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 419 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 420 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 421 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 422 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 423 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 424 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 425 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 426 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 427 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 428 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 429 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬
|
| 430 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 431 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
| 432 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 433 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 3件: IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 434 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 435 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 436 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 437 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 438 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 439 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 1件: IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 440 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 441 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 442 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 443 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 444 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 445 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 446 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 447 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 448 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 449 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 450 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 451 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 452 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 453 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PDCD1 1件: PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
| 454 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 455 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 456 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 457 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 458 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 459 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 460 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 461 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 462 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 463 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 464 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 1件: IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 465 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 466 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 467 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 468 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
JAK3 1件: JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 469 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 470 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 471 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 472 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 473 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 474 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 475 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 476 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 477 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 478 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR 1件: PGR 💬
|
Medroxyprogesterone acetate Medroxyprogesterone acetate 💬
| Medroxyprogesterone acetate | 013 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬
|
| 479 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 480 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 1件: JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 481 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 482 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 1件: IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 483 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B 1件: IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 484 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 485 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 486 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 487 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬
|
| 488 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A 1件: PDE5A 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
|
| 489 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 490 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 491 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 492 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 493 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 494 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 495 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 496 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 497 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 498 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A 1件: IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 499 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 500 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 501 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
|
| 502 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 503 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 504 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 505 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 506 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 507 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 3件: IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 508 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 509 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 510 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 511 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 512 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 2件: IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 513 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 514 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 515 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 516 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 517 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 518 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
S1PR1 2件: S1PR1, S1PR5 💬
|
Siponimod Siponimod 💬
| Siponimod | 013 2件: 13, 50 💬
|
| 519 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 520 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 521 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 522 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 523 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
IL10 1件: IL10 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 524 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
C5 1件: C5 💬
|
Ravulizumab Ravulizumab 💬
| Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬
|
| 525 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 526 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IL10 2件: IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 527 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 528 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 529 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL10 2件: IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 530 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PDCD1 1件: PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
| 531 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 532 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 533 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 534 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 535 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 536 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
CACNA1C 1件: CACNA1C 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 537 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
| 538 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
FDPS 1件: FDPS 💬
|
Risedronic acid Risedronic acid 💬
| Risedronic acid | 046 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
|
| 539 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 540 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 541 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 542 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 543 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 544 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 545 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 546 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 547 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 548 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 549 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 550 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 2件: IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 551 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 552 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 553 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 554 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 555 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 556 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 557 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 558 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 559 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 560 | Thyroid hormone synthesis 💬 7 genes, 6 drugs (DrugBank) and 7 diseases |
TPO 1件: TPO 💬
|
Methimazole Methimazole 💬
| Methimazole | 050 1件: 50 💬
|
| 561 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
CACNA1D 1件: CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 562 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 563 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 564 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 565 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 566 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 567 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 568 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 569 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 3件: IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 570 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 571 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 572 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL10 2件: IL10, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 573 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 574 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 575 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 576 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 577 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 578 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
CD86 1件: CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 579 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 1件: IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 580 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 1件: IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 581 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 582 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 583 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 584 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 585 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 586 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 587 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 588 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 589 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 590 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 591 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
| 592 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 593 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 594 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 595 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 596 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 597 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 598 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1C 2件: CACNA1C, CACNA1D 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 599 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 600 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 601 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 602 | Tyrosine metabolism 💬 10 genes, 16 drugs (DrugBank) and 18 diseases |
TPO 1件: TPO 💬
|
Methimazole Methimazole 💬
| Methimazole | 050 1件: 50 💬
|
| 603 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
| 604 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 605 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 606 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 607 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 608 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 2件: JAK1, JAK3 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 609 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 610 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CCL2 4件: CCL2, IL10, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 611 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 612 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 613 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
LTA 2件: LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 614 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
| 615 | Virion - Adenovirus 💬 2 genes, 2 drugs (DrugBank) and 26 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 616 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 617 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 618 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 619 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 620 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 621 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
| 622 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|