Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Breast cancer 💬
 4件: BRAF, FLT4, KIT, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
2 Breast cancer 💬
 3件: EGFR, ERBB2, FLT4 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
3 Breast cancer 💬
 2件: FGFR1, FLT4 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
4 Breast cancer 💬
 1件: FLT4 💬 Axitinib 💬 Axitinib 1件: 34 💬
5 Breast cancer 💬
 1件: FLT4 💬 Cediranib 💬 Cediranib 1件: 34 💬
6 Breast cancer 💬
 2件: FLT4, KIT 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
7 Calcium signaling pathway 💬
 4件: EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
8 Calcium signaling pathway 💬
 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
9 Calcium signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
10 Calcium signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
11 Calcium signaling pathway 💬
 6件: FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
12 Calcium signaling pathway 💬
 4件: FLT4, KDR, PDGFRB, RET 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
13 Focal adhesion 💬
 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
14 Focal adhesion 💬
 4件: EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
15 Focal adhesion 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
16 Focal adhesion 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
17 Focal adhesion 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
18 Focal adhesion 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
19 MAPK signaling pathway 💬
 7件: BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
20 MAPK signaling pathway 💬
 8件: CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
21 MAPK signaling pathway 💬
 4件: EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
22 MAPK signaling pathway 💬
 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
23 MAPK signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
24 MAPK signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
25 Pathways in cancer 💬
 7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
26 Pathways in cancer 💬
 7件: CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
27 Pathways in cancer 💬
 3件: EGFR, ERBB2, FLT4 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
28 Pathways in cancer 💬
 6件: FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
29 Pathways in cancer 💬
 1件: FLT4 💬 Axitinib 💬 Axitinib 1件: 34 💬
30 Pathways in cancer 💬
 1件: FLT4 💬 Cediranib 💬 Cediranib 1件: 34 💬
31 PI3K-Akt signaling pathway 💬
 8件: CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
32 PI3K-Akt signaling pathway 💬
 4件: EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
33 PI3K-Akt signaling pathway 💬
 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
34 PI3K-Akt signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
35 PI3K-Akt signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
36 PI3K-Akt signaling pathway 💬
 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
37 Rap1 signaling pathway 💬
 6件: BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
38 Rap1 signaling pathway 💬
 7件: CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
39 Rap1 signaling pathway 💬
 3件: EGFR, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
40 Rap1 signaling pathway 💬
 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
41 Rap1 signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
42 Rap1 signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
43 Ras signaling pathway 💬
 8件: CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
44 Ras signaling pathway 💬
 3件: EGFR, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
45 Ras signaling pathway 💬
 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
46 Ras signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
47 Ras signaling pathway 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
48 Ras signaling pathway 💬
 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬

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