46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

6 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-004101-27-NL (EUCTR)	15/01/2020	12/12/2019	Research into injecting golimumab less frequently by using increased doses	INDIGO: Comparing pharmacokinetic parameters of golimumab 50 mgand golimumab 100 mg with a prolonged ...	rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis MedDRA version: 21.0;Level: PT;Cl ...	Trade Name: Simponi INN or Proposed INN: GOLIMUMAB	Sint Maartenskliniek	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	35	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Netherlands
2	NCT01715896 (ClinicalTrials.gov)	March 2013	16/10/2012	A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis	A Phase 2 Exploratory Study of Mavrilimumab Versus Anti-tumor Necrosis Factor in Subjects With Rheum ...	Rheumatoid Arthritis	Biological: Golimumab 50 mg;Biological: Mavrilimumab 100 mg	MedImmune LLC	NULL	Completed	18 Years	80 Years	All	215	Phase 2	Argentina;Colombia;Czech Republic;France;Greece;Hungary;Israel;Mexico;Portugal;Russian Federation;Se ...
3	NCT01004432 (ClinicalTrials.gov)	December 2009	29/10/2009	Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or ...	A Golimumab Phase 3b, Multicenter, Switch Assessment of Subcutaneous and Intravenous Efficacy in Rhe ...	Arthritis;Arthritis, Rheumatoid;Autoimmune Diseases	Drug: Golimumab 50 mgSC;Drug: Golimumab 2 mg/kg IV;Drug: Methotrexate (MTX);Drug: Placebo SC;Drug: Plac ...	Janssen Biotech, Inc.	Merck Sharp & Dohme Corp.	Completed	18 Years	N/A	All	433	Phase 3	United States;Austria;Belgium;Canada;Germany;Greece;Sweden;United Kingdom;France;Spain
4	NCT00299546 (ClinicalTrials.gov)	February 2006	3/3/2006	A Study of the Safety and Efficacy of Golimumab (CNTO 148) in Subjects With Active Rheumatoid Arthri ...	A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Golimumab, a Fully Human Anti-T ...	Arthritis, Rheumatoid	Drug: Placebo;Biological: Golimumab 50 mg;Biological: Golimumab 100 mg	Centocor, Inc.	Schering-Plough	Completed	18 Years	N/A	All	461	Phase 3	United States;Australia;Austria;Canada;Finland;Germany;Netherlands;New Zealand;Spain;United Kingdom; ...
5	NCT00264537 (ClinicalTrials.gov)	December 2005	11/12/2005	A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Metho ...	A Multicenter, Randomized, Double-blind, Placebo-controlledTrial of Golimumab, a Fully Human Anti-TN ...	Rheumatoid Arthritis	Drug: Placebo injections;Drug: Placebo capsules;Drug: Methotrexate capsules;Biological: Golimumab 50 m ...	Centocor, Inc.	Schering-Plough	Completed	18 Years	N/A	All	637	Phase 3	United States;Argentina;Australia;Austria;Belgium;Canada;Chile;Hungary;India;Korea, Republic of;Mala ...
6	NCT00264550 (ClinicalTrials.gov)	December 2005	11/12/2005	An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Metho ...	A Multicenter, Randomized, Double-blind, Placebo-controlledTrial of Golimumab, a Fully Human Anti-TN ...	Rheumatoid Arthritis	Drug: Golimumab 100 mg;Drug: Golimumab 50 mg;Drug: Methotrexate;Drug: Placebo injection;Drug: Placebo ...	Centocor, Inc.	Schering-Plough	Completed	18 Years	N/A	All	444	Phase 3	United States;Argentina;Australia;Canada;Chile;Germany;Hungary;Korea, Republic of;Mexico;New Zealand ...

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