46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

9 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ITMCTR2100005277	2020-07-18	2021-09-05	Observation on the efficacy of Tripterygiumwilfordii polyglycosides tablets combined with Adamumab i ...	A multicenter, prospective, observational study to evaluate the efficacy and safety of Tripterygiumw ...	rheumatoid arthritis	1:Tripterygium wilfordiipolyglycoside tablets + Adamu monoclonal antibody;2:Methotrexatetablets + Ada ...	The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine	NULL	Recruiting	18	80	Both	1:30;2:30;	Phase 4	China
2	ChiCTR2100050865	2020-07-18	2021-09-05	Observation on the efficacy of Tripterygiumwilfordii polyglycosides tablets combined with Adamumab i ...	A multicenter, prospective, observational study to evaluate the efficacy and safety of Tripterygiumw ...	rheumatoid arthritis	Group 1:Tripterygium wilfordiipolyglycoside tablets + Adamu monoclonal antibody;Group 2:Methotrexatet ...	The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine	NULL	Recruiting	18	80	Both	Group 1:30;Group 2:30;	Phase 4	China
3	NCT04136262 (ClinicalTrials.gov)	November 25, 2019	21/10/2019	Tripterygium Wilfordii Hook F and Methotrexate for Postmenopausal Women With Rheumatoid Arthritis	TripterygiumWilfordii Hook F and Methotrexate for Postmenopausal Women With Rheumatoid Arthritis: a ...	Rheumatoid Arthritis	Drug: Tripterygium wilfordii Hook F (TwHF);Drug: Methotrexate;Other: Dummy Tripterygium wilfordii Hook F ...	Guang'anmen Hospital of China Academy of Chinese Medical Sciences	NULL	Recruiting	N/A	N/A	Female	300	Phase 2/Phase 3	China
4	NCT03589833 (ClinicalTrials.gov)	May 14, 2019	5/7/2018	Effectiveness and Safety of Yisaipu Combined With Tripterygium Wilfordii for Active RA	Effectiveness and Safety of Tumor Necrosis Factor Receptor Fusion Protein(Yisaipu) Combined With Tri ...	Arthritis, Rheumatoid	Drug: Tripterygium Wilfordii;Drug: Methotrexate;Drug: Yisaipu	Peking Union Medical College Hospital	NULL	Completed	18 Years	65 Years	All	504	Phase 4	China
5	NCT03337815 (ClinicalTrials.gov)	October 28, 2017	22/10/2017	A Specification Clinical Application Research of TripterygiumWilfordii Treating Rheumatoid Arthritis ...	A 24-Week, Multicenter ,Double Blind, Randomized Study to Determine the Effects and Security of Trip ...	Rheumatoid Arthritis	Drug: Treatment of MTX and TwHF placebo;Drug: Treatment of TwHF and MTX placebo	Guang'anmen Hospital of China Academy of Chinese Medical Sciences	NULL	Recruiting	45 Years	70 Years	All	264	Phase 2/Phase 3	China
6	NCT01613079 (ClinicalTrials.gov)	May 2012	4/6/2012	Efficacy and Safety of Tripterygium Wilfordii in Patients With Rheumatoid Arthritis	Evaluation of Oral T2 (Chloroform/Methanol Extract of TripterygiumWilfordii Hook F) in the Treatment ...	Arthritis, Rheumatoid	Drug: Tripterygium wilfordii Hook F;Drug: Methotrexate	Peking Union Medical College Hospital	NULL	Completed	18 Years	65 Years	Both	201	Phase 2/Phase 3	China
7	NCT02818361 (ClinicalTrials.gov)	April 2012	15/6/2016	Topical Tripterygium Wilfordii Gel for Moderate Activity Rheumatoid Arthritis	Topical TripterygiumWilfordii Gel for Treatment in Patients With Moderate Activity Rheumatoid Arthri ...	Arthritis, Rheumatoid	Drug: Topical tripterygium gel;Drug: Placebo gel	Guang'anmen Hospital of China Academy of Chinese Medical Sciences	NULL	Completed	18 Years	65 Years	All	70	N/A	China
8	NCT01961505 (ClinicalTrials.gov)	October 2011	23/9/2013	Topical Compound Tripterygium Wilfordii Hook F for Patients With Active Rheumatoid Arthritis	A Randomized Controlled Study to Determine the Effects and Safety of Topical Compound TripterygiumWi ...	Active Rheumatoid Arthritis	Drug: Topical compound tripterygium;Drug: Placebo	Guang'anmen Hospital of China Academy of Chinese Medical Sciences	NULL	Completed	18 Years	65 Years	All	70	N/A	NULL
9	NCT00062465 (ClinicalTrials.gov)	June 2003	5/6/2003	Treating Rheumatoid Arthritis With Tripterygium Wilfordi Hook F or Sulfasalazine	A 24-Week, Double Blind, Randomized Study to Determine the Effects of 24 Weeks of Dosing With Tripte ...	Rheumatoid Arthritis	Drug: TwHF	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	NULL	Completed	N/A	N/A	Both	157	Phase 2	United States

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