53. シェーグレン症候群 Sjogren syndrome Clinical trials / Disease details

臨床試験数 : 305 / 薬物数 : 325 - (DrugBank : 104) / 標的遺伝子数 : 58 - 標的パスウェイ数 : 188

10 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-003749-39-IT (EUCTR)	15/12/2021	15/10/2021	A 4 week, Phase III, multicenter, double-masked, study to evaluate safety and efficacy of Oxervate® ...	A 4 week, Phase III, multicenter, double-masked, vehicle-controlled study to evaluate safety and eff ...	Severe Sjogren’s dry eye disease MedDRA version: 21.0;Level: PT;Classification code 10040767;Term: S ...	Trade Name: Oxervate Product Name: OXERVATE Product Code: [Recombinant Human Nerve Growth Factor (rhNG ...	DOMPé FARMACEUTICI S.P.A.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	48	Phase 3	United States;Italy
2	NCT04835623 (ClinicalTrials.gov)	June 21, 2021	5/4/2021	CEQUA for Sjogren's Syndrome Dry Eye	Effects of CEQUA™ on Objective and Subjective Dry Eye Findings Associated With Sjogren's Syndrome	Dry Eye;Dry Eye Syndromes;Sjogren's Syndrome	Drug: Cyclosporine 0.09% Ophthalmic Solution	Center for Ophthalmic and Vision Research, LLC	Sun Pharmaceutical Industries Limited	Recruiting	18 Years	70 Years	All	50	Phase 4	United States
3	NCT04597762 (ClinicalTrials.gov)	August 31, 2020	16/10/2020	Effect of Ciclosporin Eyedrops on Sjögren Syndrome	Effect of Ciclosporin Eyedrops on Ocular Symptoms and Optical Quality in Patients With Sjögren Syndr ...	Dry Eye Syndromes	Drug: Cyclosporin;Drug: Hydrocortisone	Hospital Hietzing	NULL	Completed	18 Years	90 Years	All	12	N/A	Austria
4	NCT03865888 (ClinicalTrials.gov)	October 30, 2018	16/12/2018	Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjog ...	Evaluation of the Effect of Topical Application of Tacrolimus 0.03% (FK506) Eye Drops Versus Cyclosp ...	Dry Eye;Sjogren Syndrome	Drug: Cyclosporins;Drug: Tacrolimus	Pavly Moawd	NULL	Completed	20 Years	70 Years	All	60	Phase 3	Egypt
5	ChiCTR-IPR-15005990	2015-03-23	2015-02-10	Cyclosporine A in the Treatment of Interstitial Pneumonitis associated with Sjogren’s syndrome(CTRIP ...	Cyclosporine A in the Treatment of Interstitial Pneumonitis associated with Sjogren’s syndrome(CTRIP ...	Sjogren's syndrome	Treatment group:glucocorticoid+CsA;Control group:glucocorticoid+placebo;	Peking University People's Hospital	NULL	Pending	18	75	Both	Treatment group:120;Control group:120;		China
6	NCT02370550 (ClinicalTrials.gov)	March 2015	18/2/2015	Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome	Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome(CTRIP ...	Sjogren's Syndrome	Drug: Cyclosporin A;Drug: Prednisone;Drug: Placebo;Drug: Calcium carbonate D	Peking University People's Hospital	NULL	Recruiting	18 Years	75 Years	All	240	Phase 4	China
7	NCT02004067 (ClinicalTrials.gov)	January 2013	3/12/2013	Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease	Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease	Primary Sjogren Syndrome;Secondary Sjogren Syndrome;Aqueous Deficient Dry Eye Disease;Evaporative Dr ...	Drug: Restasis;Drug: Refresh Endura	Federal University of São Paulo	Allergan	Completed	18 Years	65 Years	All	100	Phase 4	Brazil
8	NCT01693393 (ClinicalTrials.gov)	March 2010	14/9/2012	Low Dose Cyclosporin A in Primary Sjögren Syndrome	A Phase II Pilot-Study With Low-dose Sandimmun Optoral (CyclosporinA) for the Treatment of Primary S ...	Sjögren´s Syndrome	Drug: Cyclosporine A	Charite University, Berlin, Germany	NULL	Completed	18 Years	75 Years	Both	30	Phase 2	Germany
9	NCT00001731 (ClinicalTrials.gov)	November 1997	3/11/1999	Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops	A Double-Masked, Randomized, Vehicle-Controlled Pilot Study of the Treatment of Keratoconjunctivitis ...	Keratoconjunctivitis Sicca;Sjogren's Syndrome	Drug: Cyclosporin A	National Eye Institute (NEI)	NULL	Completed	N/A	N/A	Both	30	Phase 2	United States
10	EUCTR2009-013976-38-DE (EUCTR)		07/12/2009	Phase II Trial of low-dose Sandimmun Optoral ® (Cyclosporine A) for the treatment of primary Sjögren ...	Phase II Trial of low-dose Sandimmun Optoral ® (Cyclosporine A) for the treatment of primary Sjögren ...	Primary Sjögren's Syndrome MedDRA version: 12.1;Level: LLT;Classification code 10059142;Term: Sjoegr ...	Trade Name: Sandimmun Optoral Product Name: Sandimmun Optoral INN or Proposed INN: CICLOSPORIN Trade Na ...	Charité Berlin, Department of rheumatology	Charité Berlin, department of rheumatology;Charité Berlin, department of rheumatology	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 2	Germany

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