63. 特発性血小板減少性紫斑病 Idiopathic thrombocytopenic purpura Clinical trials / Disease details
臨床試験数 : 391 / 薬物数 : 235 - (DrugBank : 50) / 標的遺伝子数 : 49 - 標的パスウェイ数 : 139
Showing 1 to 10 of 360 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05757570 (ClinicalTrials.gov) | May 2023 | 24/2/2023 | An Open-label Study of Povetacicept in Subjects With Autoimmune Cytopenias | A Phase 1b Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4) A Phase 1b Open-Label Study to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics o ... | Immune Thrombocytopenia;Idiopathic Thrombocytopenic Purpura;Warm Autoimmune Hemolytic Anemia;Cold Agglutinin Disease Immune Thrombocytopenia;Idiopathic Thrombocytopenic Purpura;Warm Autoimmune Hemolytic Anemia;Cold Ag ... | Drug: povetacicept | Alpine Immune Sciences, Inc. | NULL | Not yet recruiting | 18 Years | N/A | All | 42 | Phase 1 | NULL |
2 | NCT05653349 (ClinicalTrials.gov) | March 31, 2023 | 23/11/2022 | Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP) Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thromb ... | A Phase III, Randomized, Double-blind Study of Ianalumab (VAY736) Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (VAYHIT1) A Phase III, Randomized, Double-blind Study of Ianalumab (VAY736) Versus Placebo in Addition to Firs ... | Primary Immune Thrombocytopenia (ITP) | Biological: Ianalumab;Drug: Placebo;Drug: Corticosteroids | Novartis Pharmaceuticals | NULL | Recruiting | 18 Years | N/A | All | 225 | Phase 3 | Belgium;Hungary;Romania;Singapore;Spain;United Kingdom |
3 | NCT05653219 (ClinicalTrials.gov) | February 2, 2023 | 23/11/2022 | A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Imm ... | A Phase 3 Randomized, Double-blind Study of Ianalumab (VAY736) Versus Placebo in Addition to Eltrombopag in Patients With Primary Immune Thrombocytopenia (ITP) Who Had an Insufficient Response or Relapsed After First Line Steroid Treatment (VAYHIT2) A Phase 3 Randomized, Double-blind Study of Ianalumab (VAY736) Versus Placebo in Addition to Eltromb ... | Primary Immune Thrombocytopenia | Biological: Ianalumab;Drug: Eltrombopag;Drug: Placebo | Novartis Pharmaceuticals | NULL | Recruiting | 18 Years | N/A | All | 150 | Phase 3 | Czechia;Hungary;Korea, Republic of;Singapore;United Kingdom |
4 | NCT05685420 (ClinicalTrials.gov) | January 23, 2023 | 6/1/2023 | Extension Study of Herombopag for Pediatric Patients With Chronic Immune Thrombocytopenia | Extension Study of Herombopag in Children and Adolescents With Chronic Primary Immune Thrombocytopenia Extension Study of Herombopag in Children and Adolescents With Chronic Primary Immune Thrombocytopen ... | Immune Thrombocytopenia | Drug: Herombopag | Jiangsu HengRui Medicine Co., Ltd. | NULL | Not yet recruiting | 6 Years | 17 Years | All | 117 | Phase 3 | NULL |
5 | EUCTR2022-001627-32-ES (EUCTR) | 23/01/2023 | 01/11/2022 | A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltrombopag in primary immune thrombocytopenia (ITP) patients who failed steroids A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltro ... | A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) - VAYHIT2 A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltromb ... | immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immu ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Farmacéutica, S.A. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 150 | Phase 3 | United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;China;Korea, Republic of;Czechia;Turkey;Austria;United Kingdom;Czech Republic;Hungary;Mexico;Belgium;Singapore;Romania;Germany;Norway;Japan United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;Ch ... | ||
6 | EUCTR2022-001627-32-NL (EUCTR) | 29/12/2022 | 31/10/2022 | A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltrombopag in primary immune thrombocytopenia (ITP) patients who failed steroids A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltro ... | A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) - VAYHIT2 A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltromb ... | immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immu ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Pharma AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 150 | Phase 3 | United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;China;Korea, Republic of;Czechia;Turkey;Austria;United Kingdom;Czech Republic;Hungary;Mexico;Argentina;Belgium;Singapore;Romania;Germany;Norway;Japan United States;Philippines;Taiwan;Thailand;Spain;Italy;India;France;Malaysia;Australia;Netherlands;Ch ... | ||
7 | EUCTR2022-001672-34-ES (EUCTR) | 23/12/2022 | 11/10/2022 | A study of ianalumab (VAY736) in addition to first-line corticosteroids in patients with primary immune thrombocytopenia A study of ianalumab (VAY736) in addition to first-line corticosteroids in patients with primary imm ... | A phase III, randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to first-line corticosteroids in primary immune thrombocytopenia (VAYHIT1) A phase III, randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to firs ... | Primary Immune thrombocytopenia (ITP);Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] Primary Immune thrombocytopenia (ITP);Therapeutic area: Diseases [C] - Blood and lymphatic diseases ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Farmacéutica, S.A. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 225 | Phase 3 | United States;Czechia;Hong Kong;Spain;Thailand;Turkey;Austria;United Kingdom;Italy;India;France;Czech Republic;Hungary;Mexico;Argentina;Belgium;Malaysia;Singapore;Romania;Viet Nam;Australia;Germany;China;Japan United States;Czechia;Hong Kong;Spain;Thailand;Turkey;Austria;United Kingdom;Italy;India;France;Czec ... | ||
8 | EUCTR2022-001627-32-CZ (EUCTR) | 05/12/2022 | 20/10/2022 | A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltrombopag in primary immune thrombocytopenia (ITP) patients who failed steroids A phase 3, randomized, double-blind, study of ianalumab (VAY736) versus placebo in addition to eltro ... | A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response or relapsed after first line steroid treatment (VAYHIT2) - VAYHIT2 A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition to eltromb ... | immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immune thrombocytopenia;System Organ Class: 10005329 - Blood and lymphatic system disorders;Therapeutic area: Diseases [C] - Blood and lymphatic diseases [C15] immune thrombocytopenia (ITP) MedDRA version: 23.0;Level: PT;Classification code 10083842;Term: Immu ... | Product Name: Ianalumab Product Code: VAY736 INN or Proposed INN: Ianalumab | Novartis Pharma AG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 150 | Phase 3 | Singapore;United States;Czechia;Malaysia;Thailand;Austria;Netherlands;China;Korea, Republic of;France;Romania;Hungary;Japan;Philippines;United Kingdom;India;Spain;Czech Republic;Turkey;Belgium;Norway;Taiwan;Mexico;Italy;Australia;Germany Singapore;United States;Czechia;Malaysia;Thailand;Austria;Netherlands;China;Korea, Republic of;Franc ... | ||
9 | NCT05325593 (ClinicalTrials.gov) | December 2, 2022 | 7/3/2022 | Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thro ... | A Multicentre, Randomized, Open-label Study of Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia A Multicentre, Randomized, Open-label Study of Romiplostim Plus Dexamethasone vs Dexamethasone in Pa ... | Primary Immune Thrombocytopenia | Drug: romiplostim plus dexamethasone;Drug: Dexamethasone | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | NULL | Recruiting | 18 Years | N/A | All | 126 | Phase 3 | Spain |
10 | NCT05562882 (ClinicalTrials.gov) | October 15, 2022 | 28/9/2022 | A Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatment of Primary Immune Thrombocytopenia A Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatment of Primary Immune Thr ... | A Investigator-initiated Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatment of Relapsed/Refractory Primary Immune Thrombocytopenia A Investigator-initiated Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatmen ... | Immune Thrombocytopenia | Drug: Daratumumab Injection | Institute of Hematology & Blood Diseases Hospital | NULL | Not yet recruiting | 18 Years | N/A | All | 20 | Early Phase 1 | NULL |