72. 下垂体性ADH分泌異常症 Pituitary ADH secretion disorder Clinical trials / Disease details

臨床試験数 : 41 / 薬物数 : 27 - (DrugBank : 8) / 標的遺伝子数 : 7 - 標的パスウェイ数 : 10

14 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04790175 (ClinicalTrials.gov)	March 29, 2021	25/2/2021	Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH	Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in Syndrome of I ...	Antidiuretic Hormone, Inappropriate Secretion	Drug: Tolvaptan (SAMSCA)	Otsuka Pharmaceutical Co., Ltd.	NULL	Recruiting	N/A	N/A	All	300		Japan
2	NCT03048747 (ClinicalTrials.gov)	March 2, 2017	7/2/2017	A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptanin Patients With Hyponatremia ...	A Multicenter, Uncontrolled, Open-label, Dose-titration Trial to Investigate the Efficacy and Safety ...	Syndrome of Inappropriate Antidiuretic Hormone Secretion	Drug: Tolvaptan Oral Tablet	Otsuka Pharmaceutical Co., Ltd.	NULL	Completed	20 Years	85 Years	All	16	Phase 3	Japan
3	JPRN-JapicCTI-173512	02/3/2017	08/02/2017	Tolvaptan SIADH Study	A Multicenter, Uncontrolled, Open-label, Dose-titration Trial to Investigate theEfficacy and Safety ...	Syndrome of inappropriate secretion of antidiuretic hormones (SIADH)	Intervention name : Tolvaptan INN of the intervention : - Dosage And administration of the interventio ...	Otsuka Pharmaceutical Co., LTD.	NULL	complete	20	85	BOTH	16	Phase 3	Japan
4	NCT02545114 (ClinicalTrials.gov)	August 2015	2/9/2015	Tolvaptan for Patients With Acute Neurological Injuries	Use of Tolvaptanto Treat SIADH-induced Hyponatremia in Selected Patients With Acute Neurological Inj ...	Hyponatremia;SIADH	Drug: Tolvaptan	Polderman, Kees, H., MD, PhD	University of Pittsburgh	Terminated	18 Years	N/A	All	25	N/A	United States
5	EUCTR2014-001973-15-DK (EUCTR)	18/11/2014	27/06/2014	The effcts of tolvaptanon renal handling of water and salt, hormones in the blood at the circulation ...	Renal Handling of Water and Sodium in Autosomal Dominant Polycystic Kidney Disease.The effects of to ...	HyponatreamiaSIADH ( Syndrome of Inappropriate Antidiuretic Hormone Secretion) OverhydrationAutosoma ...	Trade Name: Samsca Product Name: Tolvaptan Product Code: C03XA01 INN or Proposed INN: Tolvaptan Other de ...	University Clinic in Nephrology and Hypertension, Department of Medical Research	NULL	Not Recruiting			Female: yes Male: yes			Denmark
6	EUCTR2013-003800-38-DK (EUCTR)	24/02/2014	09/12/2013	The effects of tolvaptanon renal handeling of water and salt, hormones in the blood and the circulat ...	The effects of tolvaptanon renal handling of water and sodium, vasoactive hormones and circulatory s ...	HyponatremiaSIADH (Syndrome of Inappropriate Antidiuretic Hormone secretion) MedDRA version: 14.1;Le ...	Trade Name: Samsca Product Name: Tolvaptan Product Code: C03XA01 INN or Proposed INN: Tolvaptan Other de ...	Department of Medical Research	NULL	Not Recruiting			Female: yes Male: yes	22	Phase 2	Denmark
7	NCT02009878 (ClinicalTrials.gov)	November 2013	9/12/2013	A PK Study of 3 Dosages of Tolvaptanin Patients With Syndrome of Inappropriate Antidiuretic Hormone ...	A Phase 1b, Multicenter, Pilot, Randomized, Double-blind Trial to Determine the Pharmacokinetics and ...	Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)	Drug: tolvaptan	Otsuka Pharmaceutical Development & Commercialization, Inc.	NULL	Completed	18 Years	N/A	All	30	Phase 1/Phase 2	Czech Republic;Denmark;Germany;Hungary;Spain;Sweden;United Kingdom
8	EUCTR2012-004071-39-IT (EUCTR)	16/10/2012	31/10/2012	Study on the effectiveness and safety of the treatment of hyponatremia due to inappropriate secretio ...	Study on the effectiveness and safety of the treatment of mild-moderate symptomatic hyponatremia due ...	Mild-moderate symptomatic hyponatremia due to syndrome of inappropriate secretion of antidiuretic ho ...	Trade Name: SAMSCA *10CPR 15MG INN or Proposed INN: TOLVAPTAN	FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO DI MILANO	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy
9	EUCTR2012-001169-33-DK (EUCTR)	02/07/2012	14/06/2012	Effects of the diuretic tolvaptan on nitric oxide system	Effects of tolvaptanon renal sodium and water handling and circulation during inhibition of the nitr ...	SIADH (Syndrome of inappropriate ADH production)OverhydrationHyponatrimia MedDRA version: 14.1;Level ...	Trade Name: Samsca Product Name: Tolvaptan INN or Proposed INN: Tolvaptan Other descriptive name: TOLVA ...	Department of Medical Research	NULL	Not Recruiting			Female: yes Male: yes	20	Phase 2	Denmark
10	NCT01425125 (ClinicalTrials.gov)	November 2011	25/8/2011	Fractional Urate Excretion in Nonedematous Hyponatremia	Study of Nonedematous Hyponatremia and the Utility of Fractional Urate Excretion in Hyponatremia and ...	Cerebral Hyponatremia;SIADH;Cerebral Salt-wasting Syndrome;Reset Hypothalamic Osmostat	Drug: Tolvaptan in euvolemic hyponatremia	NYU Langone Health	NULL	Withdrawn	18 Years	N/A	All	0	N/A	United States

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