AZITHROMYCIN ( DrugBank: Azithromycin )

6 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
13	多発性硬化症／視神経脊髄炎	1
84	サルコイドーシス	4
85	特発性間質性肺炎	2
96	クローン病	7
228	閉塞性細気管支炎	11
299	嚢胞性線維症	19

13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00043264 (ClinicalTrials.gov)	June 2001	7/8/2002	Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis	Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis	Multiple Sclerosis	Drug: Rifampin;Drug: Azithromycin	National Center for Research Resources (NCRR)	National Multiple Sclerosis Society	Completed	18 Years	65 Years	Both	40	Phase 2	United States

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84. サルコイドーシス

臨床試験数 : 149 / 薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04020380 (ClinicalTrials.gov)	September 6, 2019	11/7/2019	Azithromycin a Treatment for Pulmonary Sarcoidosis	A Single Arm, Open-label Exploratory Clinical Trial of Azithromycin in Pulmonary Sarcoidosis	Sarcoidosis, Pulmonary	Drug: Azithromycin 250Mg Capsule	Hull University Teaching Hospitals NHS Trust	NULL	Completed	18 Years	80 Years	All	21	Phase 2	United Kingdom
2	EUCTR2019-000580-24-GB (EUCTR)	17/05/2019	25/03/2019	A clinical trial of the antibiotic azithromycin for patients with sarcoidosis	A single arm, open-label clinical trial of azithromycinin pulmonary sarcoidosis - Azithromycinfor sa ...	Sarcoidosis;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]	Trade Name: Azithromycin Product Name: Azithromycin INN or Proposed INN: azithromycin monohydrate	Hull & East Yorkshire Hospitals NHS trust	NULL	Not Recruiting			Female: yes Male: yes	30	Phase 2	United Kingdom
3	NCT02024555 (ClinicalTrials.gov)	March 2014	26/12/2013	Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis	Investigation of the Efficacy of Antimycobacterial Therapy on Pulmonary Sarcoidosis Phase II Randomi ...	Sarcoidosis; Antimycobacterial Therapy	Drug: Levofloxacin;Drug: Ethambutol;Drug: Azithromycin;Drug: Rifampin;Drug: Placebo	Vanderbilt University	National Heart, Lung, and Blood Institute (NHLBI)	Completed	18 Years	N/A	All	97	Phase 2	United States
4	NCT01169038 (ClinicalTrials.gov)	July 2010	22/7/2010	Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis	Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis	Pulmonary Sarcoidosis;Lung Function	Drug: levaquin; ethambutol; rifampin and azithromycin.	Vanderbilt University	NULL	Completed	18 Years	75 Years	All	15	Phase 1	United States

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85. 特発性間質性肺炎

臨床試験数 : 627 / 薬物数 : 443 - (DrugBank : 120) / 標的遺伝子数 : 99 - 標的パスウェイ数 : 212

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02173145 (ClinicalTrials.gov)	August 19, 2014	23/6/2014	Azithromycin in Idiopathic Pulmonary Fibrosis	Azithromycin for the Treatment of Cough in Idiopathic Pulmonary Fibrosis- a Clinical Trial	Idiopathic Pulmonary Fibrosis;Cough	Drug: azithromycin;Drug: placebo	University Hospital Inselspital, Berne	University of Bern	Completed	18 Years	N/A	All	27	N/A	Switzerland
2	NCT01432080 (ClinicalTrials.gov)	September 2011	8/9/2011	Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post ...	Does Increasing Immunosuppression Prevent Transplant-associated Lung-disease Triggered by Viral Resp ...	Respiratory Tract Infections;Bronchiolitis Obliterans;Cryptogenic Organizing Pneumonia;Lung Diseases ...	Drug: Prednisone;Drug: Azithromycin;Drug: Montelukast;Drug: Symbicort	Maisonneuve-Rosemont Hospital	The Canadian Blood and Marrow Transplant Group	Terminated	18 Years	N/A	All	12	Phase 2	Canada

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96. クローン病

臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04186247 (ClinicalTrials.gov)	August 13, 2021	2/12/2019	Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)	Personalized AZithromycin/metronidAZole, in Combination With Standard Induction Therapy, to Achieve ...	Crohn Disease;Pediatric Crohns Disease	Drug: Azithromycin;Drug: Metronidazole;Other: Standard of Care	University of North Carolina, Chapel Hill	Crohn's and Colitis Foundation;University of Amsterdam	Recruiting	3 Years	17 Years	All	20	Phase 2	United States;Canada;Israel;Netherlands
2	EUCTR2019-004219-29-NL (EUCTR)	21/04/2020	04/02/2020	Personalized antibiotic therapy in combination with standard therapy to achieve a fecal profile asso ...	Personalized AZithromycin/metronidAZole, in combination with standard induction therapy, to achieve ...	Crohn's Disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: Azithromycin Product Name: Azithromycin INN or Proposed INN: Azithromycin Other descriptive ...	Amsterdam UMC	NULL	Not Recruiting			Female: yes Male: yes	20	Phase 2	United States;Canada;Israel;Netherlands
3	EUCTR2012-005226-29-PL (EUCTR)	16/01/2014	19/09/2013	Antibiotic therapy for children with active Crohn's disease	Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease - AZCRO	Crohn's disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: azithromycin Trade Name: metronidazole Product Name: metronidazole Product Name: azithrom ...	Erasmus MC	Hospital S. Joao;University hospital Brussel;Jagiellonian University Medical College	Not Recruiting			Female: yes Male: yes	70		Portugal;United States;Canada;Belgium;Poland;Israel;Netherlands
4	EUCTR2012-005226-29-PT (EUCTR)	20/12/2013	24/09/2013	Antibiotic therapy for children with active Crohn's disease	Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease - AZCRO	Crohn's disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: azithromycin INN or Proposed INN: azithromycin Other descriptive name: AZITHROMYCIN Trade ...	Centro Hospitalar de São João E.P.E.	NULL	Not Recruiting			Female: yes Male: yes	70	Phase 3	United States;Portugal;Canada;Poland;Belgium;Israel;Netherlands
5	EUCTR2012-005226-29-BE (EUCTR)	26/04/2013	14/03/2013	Antibiotic therapy for children with active Crohn's disease	Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease - AZCRO	Crohn's disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: azithromycin Trade Name: metronidazole Product Name: metronidazole	Wolfson Medical Center	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	70		Portugal;United States;Canada;Poland;Belgium;Israel;Netherlands
6	NCT01596894 (ClinicalTrials.gov)	October 2012	12/4/2012	Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease	A Randomized, Single Blinded, Controlled, Multi Center Phase 4 Study for Induction of Remission in A ...	Crohn's Disease	Drug: Azithromycin + Metronidazole;Drug: Metronidazole	Prof. Arie Levine	NULL	Completed	5 Years	17 Years	All	73	Phase 4	Israel
7	EUCTR2012-005226-29-NL (EUCTR)		08/03/2013	Antibiotic therapy for children with active Crohn's disease	Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease - AZCRO	Crohn's disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Product Name: azithromycin Trade Name: metronidazole Product Name: metronidazole	Wolfson Medical Center	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	70		United States;Canada;Israel;Netherlands

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228. 閉塞性細気管支炎

臨床試験数 : 97 / 薬物数 : 118 - (DrugBank : 32) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 156

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01959100 (ClinicalTrials.gov)	February 2014	7/10/2013	Efficacy of Azithromycinto Prevent Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic ...	Evaluation of the Efficacy of Azithromycinto Prevent Bronchiolitis Obliterans Syndrome After Allogen ...	Malignant Hematological Diseases	Drug: Azithromycin;Drug: Placebo	Assistance Publique - Hôpitaux de Paris	NULL	Active, not recruiting	16 Years	N/A	All	480	Phase 3	France
2	EUCTR2013-000499-14-FR (EUCTR)	30/08/2013	25/09/2015	N/A	N/A - ALLOZITHRO	MedDRA version: 18.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System ...	Trade Name: AZITHROMYCINE 250 mg Product Name: AZITHROMYCINE 250 mg INN or Proposed INN: AZITHROMYCINE ...	ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)	NULL	Not Recruiting			Female: yes Male: yes		Phase 3	France
3	EUCTR2012-003331-32-BE (EUCTR)	18/06/2013	12/11/2012	A PROSPECTIVE, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF PRE-TRANSPLANT AND PROMPT POST-TRANSPLANT TRE ...	A PROSPECTIVE, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF PRE-TRANSPLANT AND PROMPT POST-TRANSPLANT TRE ...	EARLY LUNG ALLOGRAFT FUNCTION AND OUTCOME AFTER LUNG TRANSPLANTATION MedDRA version: 14.1;Level: LLT ...	Trade Name: Azithromycin(Zitromax°) Product Name: Zitromax Product Code: not applicable INN or Proposed ...	KULeuven and University Hospitals Leuven	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 4	Belgium
4	NCT01432080 (ClinicalTrials.gov)	September 2011	8/9/2011	Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post ...	Does Increasing Immunosuppression Prevent Transplant-associated Lung-disease Triggered by Viral Resp ...	Respiratory Tract Infections;Bronchiolitis Obliterans;Cryptogenic Organizing Pneumonia;Lung Diseases ...	Drug: Prednisone;Drug: Azithromycin;Drug: Montelukast;Drug: Symbicort	Maisonneuve-Rosemont Hospital	The Canadian Blood and Marrow Transplant Group	Terminated	18 Years	N/A	All	12	Phase 2	Canada
5	NCT01307462 (ClinicalTrials.gov)	June 2011	1/3/2011	Targeted Therapy of Bronchiolitis Obliterans Syndrome	Fluticasone Propionate, Azithromycin, and Montelukast Sodium in Treating Patients With Bronchiolitis ...	Bronchiolitis Obliterans	Drug: fluticasone propionate;Drug: montelukast sodium;Drug: azithromycin	Stephanie Lee	National Cancer Institute (NCI)	Completed	6 Years	99 Years	All	36	Phase 2	United States
6	NCT01327625 (ClinicalTrials.gov)	March 2011	31/3/2011	Efficacy Study of Azithromycin-based Therapy for Bronchiolitis Obliterans	A Pilot Study Evaluating the Efficacy of Azithromycin, N-acetylcystein and Inhaled Corticosteroid Co ...	Graft vs Host Disease;Bronchiolitis Obliterans	Drug: azithromycin + N-acetylcystein + inhaled corticosteroid	Asan Medical Center	NULL	Terminated	15 Years	75 Years	Both	6	N/A	Korea, Republic of
7	EUCTR2010-018724-16-BE (EUCTR)	15/04/2010	07/04/2010	A prospective, open-label, pilot-study of azithromycinfor lymphocytic bronchi(oli)tis after lung tra ...	A prospective, open-label, pilot-study of azithromycinfor lymphocytic bronchi(oli)tis after lung tra ...	Lymphocytic airway inflammation (so-called Lymphocytic Bronchitis or Bronchiolitis) post-lung transp ...	Trade Name: Zitromax Product Name: Zitromax Product Code: Na INN or Proposed INN: OTHER SOURCES Other de ...	KULeuven and University Hospitals Leuven (Leuven Lung Transplant Group)	NULL	Not Recruiting			Female: yes Male: yes	20	Phase 4	Belgium
8	EUCTR2005-003893-46-BE (EUCTR)	03/11/2009	21/10/2009	AZITHROMYCIN IN BRONCHIOLITIS OBLITERANS SYNDROME - AZI001	AZITHROMYCIN IN BRONCHIOLITIS OBLITERANS SYNDROME - AZI001	- Chronic rejection at 1 and 2 year post-lung transplantation- Mortality at 1 and 2 year post-lung t ...	Trade Name: Zithromax Product Name: Zithromax Product Code: NA INN or Proposed INN: AZITHROMYCINDIHYDRA ...	KULeuven and University Hospitals Leuven (Leuven Lung Transplant Group)	NULL	Not Recruiting			Female: yes Male: yes	80	Phase 4	Belgium
9	EUCTR2006-000485-36-GB (EUCTR)	23/08/2006	18/09/2006	A randomised, double blind, placebo controlled study to Assess The Effect of Antibiotic Therapy on C ...	A randomised, double blind, placebo controlled study to Assess The Effect of Antibiotic Therapy on C ...	Post Lung Transplantation Chronic Rejection identified as bronchiolitis obliterans syndrome (BOS)	Product Name: Azithromycin	Newcastle upon Tyne Hospitals NHS Trust	NULL	Not Recruiting			Female: yes Male: yes	64		United Kingdom
10	NCT01009619 (ClinicalTrials.gov)	September 2005	6/11/2009	Azithromycin in Bronchiolitis Obliterans Syndrome	Randomized Double-blind Placebo-controlled Prevention Trial of Azithromycin in Lung Transplantation.	Bronchiolitis Obliterans Syndrome;Graft Rejection;Lymphocytic Bronchiolitis;Respiratory Infection	Drug: Azithromycin;Drug: Placebo	Katholieke Universiteit Leuven	University Hospital, Gasthuisberg;Fund for Scientific Research, Flanders, Belgium	Completed	18 Years	N/A	All	83	Phase 4	Belgium

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299. 嚢胞性線維症

臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05663255 (ClinicalTrials.gov)	March 1, 2023	15/12/2022	Effectiveness of CFTR Modulators According to Co-therapy	Is Effectiveness of CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators Impacted b ...	Cystic Fibrosis	Drug: Discontinuation of respiratory co-therapy (azithromycin, RhDNase, or inhaled antibiotics)	Hospices Civils de Lyon	NULL	Not yet recruiting	6 Years	N/A	All	1990		NULL
2	ChiCTR2100052906	2022-01-01	2021-11-06	A randomized controlled study of comparing the effect of two azithromycinregimens in reducing exacer ...	A randomized controlled study of comparing the effect of two azithromycinregimens in reducing exacer ...	Bronchiectasis	Daily AzithromycinGroup:Azithromycin250mg QD;Weekly AzithromycinGroup:Azithromycin500mg TIW;Placebo ...	The First People' Hospital of Jiashan	NULL	Recruiting			Both	Daily Azithromycin Group:41;Weekly Azithromycin Group:41;Placebo Group:41;	Phase 4	China
3	EUCTR2016-001440-18-NL (EUCTR)	30/05/2018	16/01/2018	The influence of cytochrome P450 3A4 inhibitors on serum levels of Ivacaftor in cystic fibrosis pati ...	Pharmacokinetic interactions between ivacaftor and cytochrome P450 3A4 inhibitors in cystic fibrosis ...	cystic fibrosis and healthy subjects;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Ne ...	Trade Name: Ivacaftor Trade Name: claritromycin 500mg film coated tablets Product Name: Claritromycin T ...	university medical center utrecht	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	12	Phase 4	Netherlands
4	NCT02677701 (ClinicalTrials.gov)	October 21, 2016	29/1/2016	Testing the Effect of Adding Chronic Oral Azithromycinto Inhaled Tobramycin in People With Cystic Fi ...	TEACH Trial: Testing the Effect of Adding CHronic Azithromycinto Inhaled Tobramycin. A Randomized, P ...	Cystic Fibrosis	Drug: azithromycin;Drug: placebo (for azithromycin);Drug: inhaled tobramycin	Seattle Children's Hospital	National Heart, Lung, and Blood Institute (NHLBI);Cystic Fibrosis Foundation;CF Therapeutics Develop ...	Completed	12 Years	N/A	All	119	Phase 4	United States
5	NCT02531984 (ClinicalTrials.gov)	August 2015	21/8/2015	The Efficacy of Azithromycin in Treating Children With Non Cystic Fibrosis Bronchiectasis	Open Trial With Randomized Withdrawal of Treatment, to Evaluate the Efficacy of Azithromycinin the T ...	Non Cystic Fibrosis Bronchiectasis in Children	Drug: Azithromycin	Assistance Publique Hopitaux De Marseille	NULL	Active, not recruiting	3 Years	17 Years	Both	100	Phase 3	NULL
6	NCT02372383 (ClinicalTrials.gov)	October 2014	20/6/2014	Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis	Pharmacokinetic Evaluation of Nontuberculous Mycobacterial Antibiotics in Cystic Fibrosis Versus Con ...	Cystic Fibrosis	Drug: Ethambutol;Drug: Rifampin;Drug: Azithromycin;Drug: Pancrelipase	University of Colorado, Denver	Cystic Fibrosis Foundation Therapeutics;Colorado Clinical & Translational Sciences Institute	Completed	16 Years	45 Years	Both	32	N/A	United States
7	NCT02803944 (ClinicalTrials.gov)	September 2014	14/6/2016	Continuous Azithromycin in Cystic Fibrosis Patients Beyond Two Years	Long Term Effects of Azithromycin in Patients With Cystic Fibrosis Using the National Database	Cystic Fibrosis	Drug: Azithromycin	Hospices Civils de Lyon	NULL	Completed	7 Years	N/A	Both	2055	N/A	France
8	NCT02054156 (ClinicalTrials.gov)	June 2014	1/2/2014	OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis	OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis: The OPTIMIZE Mul ...	Cystic Fibrosis	Drug: azithromycin;Drug: placebo;Drug: Tobramycin solution for inhalation	Bonnie Ramsey	National Heart, Lung, and Blood Institute (NHLBI)	Completed	6 Months	18 Years	All	221	Phase 3	United States
9	NCT01270074 (ClinicalTrials.gov)	April 2012	23/12/2010	Prevention of Bronchiectasis in Infants With Cystic Fibrosis	A Phase 3 Multi-centre Randomised Placebo-controlled Study of Azithromycinin the Primary Prevention ...	Cystic Fibrosis;Bronchiectasis	Drug: Azithromycin;Drug: Placebo control	The University of Queensland	Telethon Kids Institute	Completed	6 Weeks	6 Months	All	130	Phase 3	Australia;New Zealand
10	NCT03045198 (ClinicalTrials.gov)	March 2012	2/2/2017	Effect of Azithromycin on Fatty Acids in CF	Effect of Azithromycin on Lipoproteins and Docosahexaenoic Acid in Patients With Cystic Fibrosis	Cystic Fibrosis	Drug: Azithromycin	University Childrens' Hospital (Zentrum für Kinderheilkunde des Universitätsklinikum Bonn)	University of Bonn;University Hospital, Frankfurt	Unknown status	10 Years	60 Years	All	20	Phase 4	NULL

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